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One Daily Multivitamin for Men 50+

NATURELO Premium Supplements
4.8
★ ★ ★ ★ ★
(2683 ratings)
Vitamin K 120 mcg
Molybdenum 40 mcg
Product Image
Score79
A thoughtfully formed iron-free multi for men over 50, with good active vitamins but limited calcium and magnesium depth.
How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
General Health
Heart Health
Anti-Aging
Cardiovascular Support
Bone Health

Score 79

A thoughtfully formed iron-free multi for men over 50, with good active vitamins but limited calcium and magnesium depth.
How scoring works
$23.95($0.39 per serving)
Vitacost
$ 23.95
iHerb
$ 23.95
Pure Formulas
$ 23.95
Walmart
$ 23.95
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Analysis

Methylfolate, methylcobalamin, active vitamin B6, lichen-derived vitamin D3, MK-7, and natural vitamin E are strong form choices. The iron-free profile is generally appropriate for many men over 50.

Calcium and magnesium remain partial contributions, and phosphorus is minimal. The fruit and vegetable blend has no usable amount, so its practical role cannot be assessed.

One capsule simplifies long-term use and the serving cost is moderate. Vitamin K2 remains the main medicine-related consideration.

Who is it for
  • Men over 50 seeking an iron-free one-daily
  • Adults who value lichen vitamin D3 and active B vitamins
Best for
  • Age-focused maintenance
  • Vitamin D3 and K2 support
  • One-capsule convenience

Pros

  • Iron-free profile
  • Methylfolate and methylcobalamin
  • Lichen vitamin D3 and MK-7
  • One capsule daily

Cons

  • Modest calcium and magnesium
  • Unquantified food blend
  • Limited targeted mineral support

Warnings

  • Vitamin K2 can interfere with warfarin and should be taken consistently under medical guidance.

Nutrient quality

86 Highest impact

Favorable active vitamin and mineral forms strengthen broad maintenance coverage. Modest major minerals and an unquantified produce blend limit depth.

Ingredient transparency

74 High impact

Core nutrient forms and amounts are mostly specific. The produce blend, complete directions, and other ingredients remain insufficiently disclosed.

Customer satisfaction

72 High impact

The supplied average rating is very strong. Specific feedback is absent, so complaint consistency and purpose fit remain uncertain.

Value for money

86 Highest impact

Strong forms and broad maintenance coverage justify the price. Low serving cost supports good category competitiveness despite the weak produce blend.

Report analysis

Goals

General Health
General Health
Impact
Highest effect
A Goal FitB+ Strength of SupportA- CoverageB+ Formula Quality
Folate · 400 mcg DFEVitamin B12 · 2.9 mcgVitamin D · 25 mcgMagnesium · 60 mgVitamin K · 120 mcgSelenium · 50 mcgZinc · 10 mgVitamin C · 100 mg

The broad vitamin and mineral profile is well aligned with nutritional backup for older men. Active B vitamins, vitamin D3, MK-7, chelated zinc, and selenium glycinate support good form quality.

Calcium and magnesium are still modest, and the fruit and vegetable blend has no measurable amount. Vitamin K can interfere with warfarin dose control, so people taking that anticoagulant need prescriber guidance.

Study evidence
Magnesium Supportive 114 studies
Selenium Supportive 70 studies
Vitamin K Supportive 34 studies
Zinc Supportive 60 studies
Heart Health
Heart Health
Impact
Highest effect
B+ Goal FitB+ Strength of SupportB+ CoverageB- Formula Quality
Vitamin K · 120 mcgMagnesium · 60 mgVitamin B12 · 2.9 mcgVitamin B6 · 2 mgFolate · 400 mcg DFEVitamin D · 25 mcg

MK-7, vitamin D3, methylfolate, active B6, and several minerals give this older-men’s multivitamin meaningful cardiovascular relevance. The formula supports calcium handling, homocysteine metabolism, and general micronutrient adequacy, but it is not a dedicated heart product.

The MK-7 amount is clearly stated and well aligned, while 25 mcg vitamin D3 provides complementary calcium-management support. Vitamin K can interfere with warfarin and related vitamin K antagonists, so users of those medicines need clinician-guided consistency.

Study evidence
Magnesium Supportive 158 studies
Vitamin K Mixed 62 studies
Anti-Aging
Anti-Aging
Impact
High effect
B+ Goal FitB+ Strength of SupportB CoverageB- Formula Quality
Folate · 400 mcg DFEMagnesium · 60 mgVitamin B12 · 2.9 mcgVitamin K · 120 mcgVitamin D · 25 mcg

MK-7, vitamin D3, active B vitamins, and antioxidant nutrients give this older-men’s multivitamin several aging-relevant mechanisms. The formula supports vascular calcium handling, homocysteine metabolism, and micronutrient adequacy without directly targeting NAD production or mitochondrial decline.

The MK-7 amount is well aligned, and 25 mcg of vitamin D3 provides complementary support. Vitamin K can interfere with warfarin and related vitamin K antagonists, so users need clinician-guided consistency.

Study evidence
Vitamin K Supportive 27 studies
Cardiovascular Support
Cardiovascular Support
Impact
High effect
B- Goal FitB Strength of SupportC+ CoverageC+ Formula Quality
Vitamin K · 120 mcgMagnesium · 60 mgVitamin D · 25 mcgSelenium · 50 mcgVitamin B12 · 2.9 mcgVitamin B6 · 2 mgVitamin E · 17 mg a-tocopherolFolate · 400 mcg DFENiacin · 17.6 mg NEVitamin C · 100 mg

Vitamin K2 as MK-7 supports healthy calcium placement, while magnesium and antioxidant vitamins add basic cardiovascular support. The formula also supplies active folate, vitamin B6, and methylcobalamin for homocysteine-related metabolism.

Most nutrients sit near maintenance amounts, so the product is broader than it is deep for heart health. Vitamin K2 can interfere with warfarin and other vitamin K antagonist treatment, making consistent intake and clinician-directed dosing important for those users.

Study evidence
Folate Supportive 93 studies
Magnesium Supportive 123 studies
Vitamin B6 Supportive 35 studies
Vitamin K Supportive 40 studies
Bone Health
Bone Health
Impact
High effect
B Goal FitB- Strength of SupportC- CoverageC Formula Quality
Phosphorus · 8 mgVitamin K · 120 mcgMagnesium · 60 mgCalcium · 60 mgVitamin D · 25 mcgCopper · 0.5 mgManganese · 1.5 mgZinc · 10 mgVitamin C · 100 mg

Vitamin D3 and MK-7 directly support calcium absorption and placement, giving the multivitamin a useful bone-health core. Small calcium and magnesium amounts contribute breadth but cannot replace dedicated mineral intake.

The active vitamin forms are favorable and practical in one capsule. Most of the broad nutrient list is not bone specific, while MK-7 can interfere with stable warfarin dosing.

Study evidence
Calcium Supportive 144 studies
Magnesium Supportive 48 studies
Vitamin K Supportive 78 studies

Ingredients

IngredientAmount per serving
Vitamin A (natural Beta-Carotene)
 1100 mcg RAE
Vitamin C (Acerola Cherry Extract, L-Ascorbate)
 100 mg
Vitamin D3 (Cholecalciferol, Lichen)
 25 mcg
Vitamin E (D-Alpha-Tocopheryl)
 17 mg a-tocopherol
Vitamin K2 (Menaquinone, Menaquinone-7)
 120 mcg
Vitamin B1 (Thiamine Hydrochloride)
 1.3 mg
Vitamin B2 (Riboflavin)
 1.4 mg
Vitamin B3 (Niacinamide)
 17.6 mg NE
Vitamin B6 (Pyridoxal 5-Phosphate)
 2 mg
Folate (L-5-Methylfolate)
 400 mcg DFE
Vitamin B12 (Methylcobalamin)
 2.9 mcg
Biotin (D-Biotin)
 60 mcg
Vitamin B5 (D-Calcium Pantothenate)
 5.5 mg
Calcium (Aquamin, Dicalcium Phosphate)
 60 mg
Phosphorus (Dicalcium Phosphate)
 8 mg
Iodine (Kelp)
 100 mcg
Magnesium (Aquamin Magnesium)
 60 mg
Zinc (Zinc Amino Acid Chelate)
 10 mg
Selenium (Albion Selenium Glycinate Complex)
 50 mcg
Copper (Copper Aminomin)
 0.5 mg
Manganese (Manganese Sulfate)
 1.5 mg
Chromium (Chromium Polynicotinate)
 30 mcg
Molybdenum (Molybdenum Krebs Complex)
 40 mcg
Organic Fruit & Vegetable Blend
0 NP
Men 50+ Gluten Free Vegan Dairy Free Vegetarian
Report overview
Vitamin K (Menaquinone, Menaquinone-7) · 120 mcg OverallScore87
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The multivitamin for older men clearly provides MK-7 at a well-aligned amount. Dry delivery without a lipid base may reduce absorption unless the serving is taken with dietary fat. The low serving cost and effective MK-7 amount provide strong value within a broad formula. Vitamin K can counteract warfarin and other vitamin K antagonists, so users of those medicines should keep intake consistent and coordinate changes with their prescriber.

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Molybdenum (Molybdenum Krebs Complex) · 40 mcg OverallScore50
F Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyD+ Value

Vague complex or chelate naming limits confidence in the molybdenum source and its processing. The 40 mcg amount is below the target range, though it remains comfortably within adult safety limits. Serving value is limited when molybdenum is the main reason for purchase.

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Loading alternative details
87 Performance

Vitamin D3 25 mcg (1000 IU) & K2 120 mcg

Natural Factors
<p>Moderate vitamin D3 and a meaningful MK-7 amount create a focused bone and cardiovascular formula. Compared with the broad men’s over-50 multivitamin, It improves vitamin K form and purpose but leaves out the broader nutrient coverage of a daily multivitamin.</p>
86 Performance

NAC Detox Regulators

Doctor's Best
<p>A substantial NAC serving with selenium and molybdenum creates a compact antioxidant-support formula with clearly named forms. Compared with the broad men’s over-50 multivitamin, Its purpose is narrower than a multivitamin, and NAC can intensify nitroglycerin-related headache or low blood pressure.</p>
86 Performance

Liquid D-3 & MK-7

NOW
<p>Menaquinone-7 and substantial vitamin D3 provide focused bone and cardiovascular support in a convenient liquid. Compared with the broad men’s over-50 multivitamin, The formula is stronger for this narrow goal but omits the original product's broad vitamin and mineral base.</p>
78 Budget

Women's One Daily

INNATE Response Formulas
<p>Broad vitamin coverage and chelated minerals preserve a one-daily format at a lower serving cost. Older folate and vitamin B12 forms and a women-focused design make it a weak match for men over 50.</p>
88 Budget

Vitamin K2 MK-7 100 mcg

Nutricost
<p>A meaningful MK-7 amount offers focused vitamin K support at a substantially lower serving cost. Compared with the broad men’s over-50 multivitamin, It does not replace broad vitamin and mineral coverage, and vitamin K can interfere with warfarin-type medicines.</p>
86 Budget

Moly-B

Carlson
<p>Molybdenum glycinate chelate provides a specific, easy-to-assess form at a much lower recurring cost. Compared with the broad men’s over-50 multivitamin, It is a targeted molybdenum product rather than a multivitamin and should not be treated as a complete replacement.</p>
86 Value

Vitamin K2 100 mcg + Vitamin D3 125 mcg

Nutricost
<p>A softgel combines meaningful MK-7 with concentrated vitamin D3 at a very low serving cost. Compared with the broad men’s over-50 multivitamin, It offers strong targeted value but is not a full multivitamin, and total vitamin D intake needs consideration.</p>
83 Value

Liquid Molybdenum

NutriCology
<p>A clearly identified soluble molybdate form and conservative amount provide focused molybdenum support at a low recurring cost. Compared with the broad men’s over-50 multivitamin, Missing complete directions are a limitation, and the single-mineral formula cannot replace broad daily coverage.</p>
86 Value

Vitamins D3 2500 IU (62.5 mcg) & K2 120 mcg

NaturesPlus
<p>MK-7 and substantial vitamin D3 provide strong targeted value for bone and cardiovascular support. Compared with the broad men’s over-50 multivitamin, The dry tablet lacks a lipid carrier and omits the many vitamins and minerals supplied by a multivitamin.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  2. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials.
    Huang ZB; Wan SL; Lu YJ; Ning L; Liu C; Fan SW · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Meta-analysis6,759 participants19 studies pooledBone Health forVitamin K
  3. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  4. Comparison of concurrent treatment with vitamin K2 and risedronate compared with treatment with risedronate alone in patients with osteoporosis: Japanese Osteoporosis Intervention Trial-03.
    Tanaka S; Miyazaki T; Uemura Y; Miyakawa N; Gorai I; Nakamura T; Fukunaga M; Ohashi Y; Ohta H; Mori S; Hagino H; Hosoi T; Sugimoto T; Itoi E; Orimo H; Shiraki M · Journal of bone and mineral metabolism · 2018
    Randomized trial1,874 participantsBone Health forVitamin K
  5. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  6. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  7. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  8. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
  9. Interventions to Attenuate Cardiovascular Calcification Progression: A Systematic Review of Randomized Clinical Trials.
    Murali S; Smith ER; Tiong MK; Tan SJ; Toussaint ND · Journal of the American Heart Association · 2024
    Systematic review9,901 participants49 studies pooledCardiovascular Support forVitamin K
  10. Intake of dietary phylloquinone and menaquinones and risk of stroke.
    Vissers LE; Dalmeijer GW; Boer JM; Monique Verschuren WM; van der Schouw YT; Beulens JW · Journal of the American Heart Association · 2014
    Cohort study35,476 participantsCardiovascular Support forVitamin K
  11. Circulating uncarboxylated matrix Gla protein, a marker of vitamin K status, as a risk factor of cardiovascular disease.
    van den Heuvel EG; van Schoor NM; Lips P; Magdeleyns EJ; Deeg DJ; Vermeer C; den Heijer M · Maturitas · 2014
    Cohort study577 participantsCardiovascular Support forVitamin K
  12. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging General Health forVitamin K
  13. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  14. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  15. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  16. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  17. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  18. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  19. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  20. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  21. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  22. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  23. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  24. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  25. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  26. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  27. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  28. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  29. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  30. Associations of dietary folate, vitamin B6 and B12 intake with cardiovascular outcomes in 115664 participants: a large UK population-based cohort.
    Zhang B; Dong H; Xu Y; Xu D; Sun H; Han L · European journal of clinical nutrition · 2023
    Cohort study115,664 participantsCardiovascular Support forFolate
  31. Folate, Homocysteine, and Adverse Outcomes After Ischemic Stroke.
    Shi M; Zheng J; Liu Y; Mao X; Wu X; Chu M; Niu H; Sun L; Chang X; He Y; Liu Y; Guo D; Zhang Y; Zhu Z; Zhao J · Journal of the American Heart Association · 2024
    Cohort study3,530 participantsCardiovascular Support forFolate
  32. Effect of folic acid on endothelial function following acute myocardial infarction.
    Moens AL; Claeys MJ; Wuyts FL; Goovaerts I; Van Hertbruggen E; Wendelen LC; Van Hoof VO; Vrints CJ · The American journal of cardiology · 2007
    Randomized trial40 participantsCardiovascular Support forFolate
  33. Folic acid enhances endothelial function and reduces blood pressure in smokers: a randomized controlled trial.
    Mangoni AA; Sherwood RA; Swift CG; Jackson SH · Journal of internal medicine · 2003
    Randomized trial24 participantsCardiovascular Support forFolate
  34. 5-methyltetrahydrofolate, the active form of folic acid, restores endothelial function in familial hypercholesterolemia.
    Verhaar MC; Wever RM; Kastelein JJ; van Dam T; Koomans HA; Rabelink TJ · Circulation · 1998
    Non-randomized trial20 participantsCardiovascular Support forFolate
  35. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  36. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  37. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  38. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  39. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  40. Association between serum pyridoxal 5'-phosphate levels and all-cause, cardiovascular mortality, and cardiovascular disease in adults: a population-based cohort study.
    Xuan C; Liu RH; Zhao C; Li J; Zhou TT; Tian QW; He GW · Therapeutic advances in chronic disease · 2024
    Cohort studyCardiovascular Support forVitamin B6
  41. Folate and vitamin B6 rapidly normalize endothelial dysfunction in children with type 1 diabetes mellitus.
    MacKenzie KE; Wiltshire EJ; Gent R; Hirte C; Piotto L; Couper JJ · Pediatrics · 2006
    Randomized trial124 participantsCardiovascular Support forVitamin B6
  42. Pyridoxine improves endothelial function in cardiac transplant recipients.
    Miner SE; Cole DE; Evrovski J; Forrest Q; Hutchison S; Holmes K; Ross HJ · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2001
    Randomized trial31 participantsCardiovascular Support forVitamin B6
  43. Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women.
    Rimm EB; Willett WC; Hu FB; Sampson L; Colditz GA; Manson JE; Hennekens C; Stampfer MJ · JAMA · 1998
    Cohort study80,082 participantsCardiovascular Support forVitamin B6
  44. Efficacy and safety of pyridoxal 5'-phosphate (MC-1) in high-risk patients undergoing coronary artery bypass graft surgery: the MEND-CABG II randomized clinical trial.
    MEND-CABG II Investigators; Alexander JH; Emery RW; Carrier M; Ellis SJ; Mehta RH; Hasselblad V; Menasche P; Khalil A; Cote R; Bennett-Guerrero E; Mack MJ; Schuler G; Harrington RA; Tardif JC · JAMA · 2008
    Randomized trial3,023 participantsCardiovascular Support forVitamin B6
  45. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  46. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support Heart Health forVitamin K
  47. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  48. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  49. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  50. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  51. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  52. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  53. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  54. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  55. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  56. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  57. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  58. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  59. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  60. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  61. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  62. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  63. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  64. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  65. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  66. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  67. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  68. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  69. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K