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Vision Sharp Multi-Nutrient Eye Health

Irwin Naturals
4.5
★ ★ ★ ★ ★
(2571 ratings)
Flavonoid 30 mg
Ginkgo
Manganese 2 mg
Omega-3 303 mg
Fish Oil 1010 mg
Protein 1 Gram(s)
Product Image
Score75
A broad, well-disclosed eye-support blend with useful carotenoids and botanical markers. The high vitamin A amount and poorly characterized fish oil are meaningful drawbacks.
How scoring works
Quantity:42 Softgel(s) • (21 servings)
Goals:
Vision Support
Mental Focus
Brain Health
Productivity Boost

Score 75

A broad, well-disclosed eye-support blend with useful carotenoids and botanical markers. The high vitamin A amount and poorly characterized fish oil are meaningful drawbacks.
How scoring works
$24.99($1.19 per serving)
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$ 24.99
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$ 24.99
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$ 24.99
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$ 24.99
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Analysis

The eye-focused core is the main strength. Lutein and zeaxanthin use a practical pairing, while bilberry discloses its anthocyanidin content and ginkgo lists both flavone glycosides and terpene lactones.

Antioxidant vitamins, zinc, and omega-3 fats broaden the formula, but quality is uneven. Zinc oxide is a less appealing form, and the fish oil provides only a modest total omega-3 amount without separate EPA and DHA figures or a stated molecular form.

The formula fits someone who wants broad eye support and also values some circulation-related cognitive support from ginkgo. The high vitamin A amount and the combination of ginkgo with fish oil make the safety trade-offs more important than they would be in a simpler lutein-and-zeaxanthin product.

Who is it for
  • Adults seeking broad daily eye-nutrient support
  • People who want lutein and zeaxanthin alongside antioxidant nutrients
  • Adults interested in added ginkgo and bilberry rather than a basic carotenoid formula
Best for
  • Vision support
  • Macular pigment nutrient coverage
  • Broad antioxidant support for the eyes

Pros

  • Provides lutein and zeaxanthin in a complementary pairing
  • Quantifies bilberry anthocyanidins
  • Discloses ginkgo flavone glycosides and terpene lactones
  • Uses anchovy and sardine as the fish-oil sources
  • Combines carotenoids, botanicals, and antioxidant nutrients

Cons

  • Vitamin A amount is unusually high for routine general use
  • Fish oil does not separate EPA from DHA
  • Omega-3 molecular form is not stated
  • Zinc is supplied as zinc oxide
  • Omega-3 concentration is modest relative to the total fish-oil amount

Warnings

  • The high vitamin A amount includes beta-carotene; current and former smokers should discuss high-dose beta-carotene supplementation with a clinician before use.
  • Ginkgo combined with fish oil may add to bleeding risk with anticoagulant or antiplatelet medicines such as warfarin, clopidogrel, or aspirin.
  • The fish oil comes from anchovy and sardine, so it is not suitable for people with allergies to those fish.

Nutrient quality

85 Highest impact

Well-characterized carotenoids, bilberry markers, and ginkgo markers give the eye formula strong active quality and useful doses. Zinc oxide, unspecified omega-3 form, and a bleeding concern from ginkgo with fish oil are the main limitations.

.

Ingredient transparency

68 High impact

Major carotenoids and botanical marker amounts are disclosed clearly. Unspecified omega-3 form, missing EPA and DHA amounts, unusable minor-ingredient entries, and absent non-active ingredients leave important gaps.

.

Customer satisfaction

69 High impact

The available satisfaction metric is moderately favorable and supported by a large sample. Specific experience details are absent, so repeated complaints and purpose fit remain uncertain.

.

Value for money

81 Highest impact

Comprehensive eye-specific ingredients and quantified botanical markers support reasonable value at a premium serving cost. Weak omega-3 disclosure and incomplete minor-ingredient details prevent the formula from leading its category.

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Report analysis

Goals

Vision Support
Vision Support
Impact
Highest effect
A Goal FitA- Strength of SupportA CoverageA- Formula Quality
Zinc · 15 mgVitamin E · 80 mgVitamin C · 400 mgVitamin A · 8600 mcg

Lutein, zeaxanthin, omega-3, bilberry, ginkgo, vitamins A, C, and E, and zinc create excellent eye-specific alignment. The 10-to-2 macular pigment pattern and broad antioxidants closely reflect established ocular support logic.

Zinc uses oxide and omega-3 is moderate, but the main carotenoids and botanical markers are well disclosed. It is the most complete vision-focused formula in this batch.

Study evidence
Ginkgo Supportive 11 studies
Zinc Supportive 39 studies
Mental Focus
Mental Focus
Impact
High effect
B Goal FitB+ Strength of SupportC+ CoverageC+ Formula Quality

A standardized ginkgo extract provides meaningful focus support through cerebral blood flow, while bilberry and omega-3s add eye and membrane-related context. The product's main purpose is vision, but ginkgo remains directly relevant to attention.

No stimulant, theanine, or neurotransmitter precursor broadens the cognitive effect. Ginkgo combined with fish oil may increase bleeding risk for people using anticoagulant or antiplatelet medicines.

Study evidence
Ginkgo Supportive 28 studies
Brain Health
Brain Health
Impact
High effect
C+ Goal FitB+ Strength of SupportC+ CoverageC Formula Quality

A clinically relevant ginkgo amount with disclosed flavone and terpene markers provides situational cognitive support. Omega fats and antioxidant nutrients add some structural and oxidative-stress coverage, although the formula is aimed mainly at eye health.

Disclosure for the lead brain-relevant ingredient is stronger than in many generic ginkgo products. Ginkgo with fish oil may increase bleeding concern for people using anticoagulant or antiplatelet medicines.

Study evidence
Ginkgo Supportive 90 studies
Productivity Boost
Productivity Boost
Impact
High effect
B- Goal FitB Strength of SupportC+ CoverageD+ Formula Quality
Zinc · 15 mgOmega-3 · 303 mg

A standardized ginkgo dose provides the strongest case for focus and mental clarity. The label specifies flavone glycosides and terpene lactones, which improves confidence in the extract.

The omega-3 amount is modest and no stimulant, precursor, or adaptogen broadens acute productivity support. Most remaining ingredients target eye health rather than cognitive performance.

Study evidence
Ginkgo Supportive 20 studies
Ginkgo Supportive 12 studies
Omega-3 Supportive 46 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Moderate effect
C Goal FitD+ Strength of SupportD+ CoverageC+ Formula Quality
Fish Oil · 1010 mgVitamin E · 80 mgVitamin C · 400 mg

Omega-3 fats, vitamin C, vitamin E, and zinc provide antioxidant and lipid-mediator support. The eye-health formula has moderate anti-inflammatory relevance but no direct botanical centerpiece.

Omega-3 content is only 303 mg, and ginger has no disclosed amount. Clear antioxidant doses help, while fish-oil form and botanical detail remain limited.

Study evidence
Fish Oil Supportive 68 studies
Ginger Supportive 30 studies
Vitamin C Supportive 50 studies
Vitamin E Supportive 20 studies
Zinc Supportive 64 studies
Cardiovascular Support
Cardiovascular Support
Impact
Moderate effect
C- Goal FitC- Strength of SupportC- CoverageC- Formula Quality
Fish Oil · 1010 mgVitamin E · 80 mgVitamin C · 400 mg

Standardized ginkgo adds circulation support, while omega-three fats and vitamin C provide smaller lipid and antioxidant contributions. Disclosure of ginkgo terpene lactones improves confidence in that botanical.

The omega-three amount is modest and does not separate EPA from DHA or identify molecular form. Ginkgo may increase bleeding tendency when combined with anticoagulant or antiplatelet medicines.

Study evidence
Fish Oil Supportive 185 studies
Vitamin C Supportive 101 studies
Cognitive Support
Cognitive Support
Impact
Moderate effect
D+ Goal FitB- Strength of SupportD- CoverageD- Formula Quality

Standardized ginkgo provides a credible circulation-related cognitive pathway. The disclosed terpene lactone amount supports confidence in the extract quality.

The rest of the formula is designed for eye health and does not add meaningful memory, neurotransmitter, or stress support. Cognitive relevance is therefore narrow despite a well-characterized ginkgo ingredient.

Study evidence
Ginkgo Supportive 87 studies

Ingredients

IngredientAmount per serving
Calories
20 Calorie(s)
Total Fat
1 Gram(s)
Cholesterol
5 mg
Total Carbohydrates
1 Gram(s)
Protein
1 Gram(s)
Vitamin A
8600 mcg
Vitamin C
400 mg
Vitamin E
80 mg
Zinc
15 mg
Manganese
2 mg
Fish Oil
1010 mg
Omega-3 Fatty Acids
303 mg
Bilberry Fruit Extract
320 mg
Anthocyanidins
80 mg
Ginkgo leaf extract
120 mg
Flavone Glycosides
29 mg
Terpene Lactones
7.2 mg
Citrus Bioflavonoids
38 mg
Bioflavonoids
30 mg
Lutein
10 mg
Zeaxanthin
2 mg
BioPerine Complex
12 mg
BioPerine
0 NP
Ginger Rhizome Extract
0 NP
Adults 18–50 Women
Report overview
Flavonoid · 30 mg OverallScore98
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA Value

Bilberry anthocyanidins and ginkgo flavone glycosides are quantified at substantial amounts, creating unusually strong marker disclosure. Liquid softgels with fish oil, BioPerine, and ginger provide multiple absorption supports.

The active-flavonoid dose is well within the useful range and justifies the premium better than a basic extract. Ginkgo and fish oil may add to bleeding risk with warfarin or antiplatelet medicines, so that combination warrants clinician review.

View ingredientView products
Ginkgo · 120 mg OverallScore59
D- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The extract reaches an effective amount and confirms the terpene lactone level, but flavone glycoside standardization remains unverified. The exact standalone amount is clear, but no qualifying ginkgolic acid purity assurance is supplied. Ginkgo may increase bleeding risk with anticoagulant or antiplatelet medicines.

View ingredientView products
Manganese · 2 mg OverallScore38
F Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value

The eye-health formula discloses a maintenance manganese amount but omits the chemical source. The elemental amount is suitable for daily maintenance but modest for targeted bone or joint support. The high serving cost weakens value for someone focused on manganese alone.

View ingredientView products
Loading alternative details
64 Performance

AREDS 2 Plus Multi-Vitamin

EyePromise
<p>The closest eye-focused option keeps lutein at 10 mg, raises zeaxanthin to 10 mg, and adds vitamin D3 plus natural vitamin E. It lacks bilberry, ginkgo, zinc, vitamin C, and manganese, while its 190 mg of omega-3 is smaller and does not separate EPA from DHA.</p>
70 Performance

Fish Oil 1000 mg

Spring Valley
<p>Triglyceride fish oil and a clearly stated 260 mg combined EPA and DHA amount improve the form and fatty-acid disclosure of the omega-3 portion. The total omega-3 amount is similar to the original, but the formula does not provide its carotenoids, bilberry, ginkgo, antioxidant vitamins, or minerals.</p>
64 Performance

Fish Oil 2400 mg

Nature's Bounty
<p>A 1,200 mg total omega-3 amount provides much deeper marine-fatty-acid coverage than the original 303 mg. The ethyl-ester form is stated, but EPA and DHA are not quantified separately and the product offers none of the original eye-focused carotenoids, botanicals, vitamins, or minerals.</p>
71 Budget

Fish Oil 1200 mg

Nature's Bounty
<p>The much lower serving cost still provides 360 mg of total omega-3 and names anchovy, herring, mackerel, and sardine as sources. It does not replace lutein, zeaxanthin, bilberry, ginkgo, or the antioxidant vitamins, and separate EPA and DHA amounts remain unclear.</p>
65 Budget

Fish Oil 1000 mg

Sundown
<p>The low serving cost provides 300 mg of total omega-3, close to the original fish-oil contribution. It gives up the original eye-focused nutrients, while EPA, DHA, molecular form, source, and quality testing are not disclosed.</p>
65 Budget

Fish Oil 1200 mg

21st Century
<p>The lower-cost serving raises total omega-3 slightly to 360 mg in a simple fish-oil concentrate. It is economical for basic omega-3 use, but it lacks the original lutein, zeaxanthin, bilberry, ginkgo, vitamins, and minerals and does not state EPA or DHA amounts.</p>
63 Value

Fish Oil 1200 mg

Nature's Bounty
<p>A substantially lower serving cost delivers 720 mg of total omega-3, more than twice the original amount. The value is strongest for general fish-oil use because EPA, DHA, oil form, source, and testing are unclear and all eye-focused nutrients are absent.</p>
64 Value

Fish Oil 1200 mg

Sundown
<p>The inexpensive serving supplies 720 mg of total omega-3, giving more active marine fat for the recurring cost. It does not replace lutein, zeaxanthin, bilberry, ginkgo, vitamins, or minerals, and separate EPA and DHA amounts are missing.</p>
65 Value

Fish Oil 1000 mg

21st Century
<p>The low serving cost preserves a similar 300 mg total omega-3 amount in a simple concentrate. It offers practical economy only for basic fish-oil use, since EPA, DHA, molecular form, sourcing, quality testing, and the original eye-support ingredients are not provided.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Efficacy and adverse effects of ginkgo biloba for cognitive impairment and dementia: a systematic review and meta-analysis.
    Tan MS; Yu JT; Tan CC; Wang HF; Meng XF; Wang C; Jiang T; Zhu XC; Tan L · Journal of Alzheimer's disease : JAD · 2015
    Meta-analysis2,561 participants9 studies pooledBrain Health forGinkgo
  2. Ginkgo for elderly people with dementia and age-associated memory impairment: a randomized clinical trial.
    van Dongen M; van Rossum E; Kessels A; Sielhorst H; Knipschild P · Journal of clinical epidemiology · 2003
    Randomized trial214 participantsBrain Health forGinkgo
  3. Ginkgo biloba for cognitive impairment and dementia.
    Wieland LS; Ludeman E; Chi Y; Feinberg TM; Chen IH; Chen KH; Zhu Y; Wolverson E; Amri H · The Cochrane database of systematic reviews · 2026
    Meta-analysis10,613 participants82 studies pooledBrain Health Cognitive Support forGinkgo
  4. Effect of Ginkgo biloba extracts in the prevention of posterior capsule opacification after cataract surgery: A randomized clinical trial.
    Amiri AA; Jafari R; Amiri AA; Rad HA; Daneshvar F; Charati JY; Amiri AA · Oman journal of ophthalmology · 2025
    Randomized trial144 participantsVision Support forGinkgo
  5. Ginkgo biloba--an appraisal.
    Dubey AK; Shankar PR; Upadhyaya D; Deshpande VY · Kathmandu University medical journal (KUMJ) · 2007
    Narrative reviewVision Support forGinkgo
  6. Electrophysiological analysis of the effects of ginkgo biloba on visual processing in older healthy adults.
    Page JW; Findley J; Crognale MA · The journals of gerontology. Series A, Biological sciences and medical sciences · 2006
    Clinical trialVision Support forGinkgo
  7. Efficacy of Ginkgo biloba extract EGb 761® in dementia with behavioural and psychological symptoms: A systematic review.
    von Gunten A; Schlaefke S; Überla K · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2017
    Meta-analysis1,628 participants4 studies pooledCognitive Support Brain Health forGinkgo
  8. Ginkgo biloba Extract (EGb761), Cholinesterase Inhibitors, and Memantine for the Treatment of Mild-to-Moderate Alzheimer's Disease: A Network Meta-Analysis.
    Thancharoen O; Limwattananon C; Waleekhachonloet O; Rattanachotphanit T; Limwattananon P; Limpawattana P · Drugs & aging · 2019
    Meta-analysisCognitive Support forGinkgo
  9. Dose-dependent effects of fish oil on cardio-metabolic biomarkers in healthy middle-aged and elderly Chinese people: a double-blind randomized controlled trial.
    Song J; Hu M; Li C; Yang B; Ding Q; Wang C; Mao L · Food & function · 2018
    Randomized trial201 participantsAnti-Inflammatory Support forFish Oil
  10. Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients.
    Lin YL; Wang CL; Chiang TI · Frontiers in nephrology · 2024
    Randomized trial60 participantsAnti-Inflammatory Support forFish Oil
  11. Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial.
    Yang B; Ren XL; Li ZH; Shi MQ; Ding F; Su KP; Guo XJ; Li D · Food & function · 2020
    Randomized trial77 participantsAnti-Inflammatory Support forFish Oil
  12. The effects of ω-3 fish oil emulsion-based parenteral nutrition plus combination treatment for acute paraquat poisoning.
    Meng Z; Dong Y; Gao H; Yao D; Gong Y; Meng Q; Zheng T; Cui X; Su X; Tian Y · The Journal of international medical research · 2019
    Randomized trial174 participantsAnti-Inflammatory Support forFish Oil
  13. Effects of Omega-3 Fatty Acid Intake in Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Liu R; Jiang J; Fu Z; Liu C; Yao L; Quan H · Journal of the American Nutrition Association · 2022
    Meta-analysis49 studies pooledAnti-Inflammatory Support forFish Oil
  14. The effect of ginger supplementation on serum C-reactive protein, lipid profile and glycaemia: a systematic review and meta-analysis.
    Mazidi M; Gao HK; Rezaie P; Ferns GA · Food & nutrition research · 2022
    Meta-analysis9 studies pooledAnti-Inflammatory Support forGinger
  15. Ginger supplementation and metabolic health: an umbrella review of meta-analyses of randomized trials.
    Musazadeh V; Morvaridi M; Hosseini-Roknabadi SM; Mahmoudinezhad M; Jafari A; Shidfar F · Diabetology & metabolic syndrome · 2026
    Meta-analysis43,570 participants36 studies pooledAnti-Inflammatory Support forGinger
  16. Effect of Ginger Supplementation on Proinflammatory Cytokines in Older Patients with Osteoarthritis: Outcomes of a Randomized Controlled Clinical Trial.
    Mozaffari-Khosravi H; Naderi Z; Dehghan A; Nadjarzadeh A; Fallah Huseini H · Journal of nutrition in gerontology and geriatrics · 2017
    Randomized trial120 participantsAnti-Inflammatory Support forGinger
  17. Effects of Ginger Supplementation on Markers of Inflammation and Functional Capacity in Individuals with Mild to Moderate Joint Pain.
    Broeckel J; Estes L; Leonard M; Dickerson BL; Gonzalez DE; Purpura M; Jäger R; Sowinski RJ; Rasmussen CJ; Kreider RB · Nutrients · 2025
    Randomized trial30 participantsAnti-Inflammatory Support forGinger
  18. The effect of ginger supplementation on some immunity and inflammation intermediate genes expression in patients with active Rheumatoid Arthritis.
    Aryaeian N; Shahram F; Mahmoudi M; Tavakoli H; Yousefi B; Arablou T; Jafari Karegar S · Gene · 2019
    Randomized trial70 participantsAnti-Inflammatory Support forGinger
  19. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  20. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  21. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  22. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  23. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  24. Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
    Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
    Randomized trial110 participantsAnti-Inflammatory Support forVitamin E
  25. Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
    Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
    Meta-analysis495 participants12 studies pooledAnti-Inflammatory Support forVitamin E
  26. Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
    Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
    Meta-analysis46 studies pooledAnti-Inflammatory Support forVitamin E
  27. Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
    Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
    Meta-analysis8 studies pooledAnti-Inflammatory Support forVitamin E
  28. Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
    Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
    Randomized trial71 participantsAnti-Inflammatory Support forVitamin E
  29. Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agent.
    Bao B; Prasad AS; Beck FW; Fitzgerald JT; Snell D; Bao GW; Singh T; Cardozo LJ · The American journal of clinical nutrition · 2010
    Randomized trial40 participantsAnti-Inflammatory Support forZinc
  30. Zinc Supplementation in Individuals with Prediabetes and type 2 Diabetes: a GRADE-Assessed Systematic Review and Dose-Response Meta-analysis.
    Nazari M; Nikbaf-Shandiz M; Pashayee-Khamene F; Bagheri R; Goudarzi K; Hosseinnia NV; Dolatshahi S; Omran HS; Amirani N; Ashtary-Larky D; Asbaghi O; Ghanavati M · Biological trace element research · 2024
    Meta-analysis23 studies pooledAnti-Inflammatory Support forZinc
  31. The Effects of Zinc Supplementation on C-Reactive Protein and Inflammatory Cytokines: A Meta-Analysis and Systematical Review.
    Ceylan MN; Akdas S; Yazihan N · Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2022
    Meta-analysis73 studies pooledAnti-Inflammatory Support forZinc
  32. The Effects of Zinc Sulfate Supplementation on Serum Copeptin, C-Reactive Protein and Metabolic Markers in Zinc-Deficient Diabetic Patients on Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Hosseini R; Montazerifar F; Shahraki E; Karajibani M; Mokhtari AM; Dashipour AR; Ferns GA; Jalali M · Biological trace element research · 2021
    Randomized trial46 participantsAnti-Inflammatory Support forZinc
  33. Zinc supplementation and cardiovascular disease risk factors: A GRADE-assessed systematic review and dose-response meta-analysis.
    Nazari M; Ashtary-Larky D; Nikbaf-Shandiz M; Goudarzi K; Bagheri R; Dolatshahi S; Omran HS; Amirani N; Ghanavati M; Asbaghi O · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2023
    Meta-analysis75 studies pooledAnti-Inflammatory Support forZinc
  34. Ginkgo biloba extract EGb 761 is safe and effective in the treatment of mild dementia - a meta-analysis of patient subgroups in randomised controlled trials.
    Riepe M; Hoerr R; Schlaefke S · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2025
    Meta-analysis782 participants4 studies pooledBrain Health Productivity Boost forGinkgo
  35. Ginkgo biloba extract EGb 761® improves cognition and overall condition after ischemic stroke: Results from a pilot randomized trial.
    Cui M; You T; Zhao Y; Liu R; Guan Y; Liu J; Liu X; Wang X; Dong Q · Frontiers in pharmacology · 2023
    Randomized trial201 participantsBrain Health Productivity Boost forGinkgo
  36. Ginkgo biloba extract EGb 761® in dementia with neuropsychiatric features: a randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of 240 mg.
    Herrschaft H; Nacu A; Likhachev S; Sholomov I; Hoerr R; Schlaefke S · Journal of psychiatric research · 2012
    Randomized trial410 participantsBrain Health forGinkgo
  37. Marine Omega-3 Supplementation and Cardiovascular Disease: An Updated Meta-Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants.
    Hu Y; Hu FB; Manson JE · Journal of the American Heart Association · 2020
    Meta-analysis127,477 participants13 studies pooledCardiovascular Support forFish Oil
  38. Impact of omega-3 fatty acids on hypertriglyceridemia, lipidomics, and gut microbiome in patients with type 2 diabetes.
    Lu J; Liu R; Ren H; Wang S; Hu C; Shi Z; Li M; Liu W; Wan Q; Su Q; Li Q; Zheng H; Qu S; Yang F; Ji H; Lin H; Qi H; Wu X; Wu K; Chen Y; Xu Y; Xu M; Wang T; Zheng J; Ning G; Zheng R; Bi Y; Zhong H; Wang W · Med (New York, N.Y.) · 2025
    Randomized trial309 participantsCardiovascular Support forFish Oil
  39. A systematic review of fish-oil supplements for the prevention and treatment of hypertension.
    Campbell F; Dickinson HO; Critchley JA; Ford GA; Bradburn M · European journal of preventive cardiology · 2013
    Meta-analysis1,524 participants17 studies pooledCardiovascular Support forFish Oil
  40. Effects of fish oil-derived fatty acids on suboptimal cardiovascular health: A multicenter, randomized, double-blind, placebo-controlled trial.
    Zeng Q; Dong SY; Liu YP; Fu J; Shuai P; Zhao ZM; Li TX · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2017
    Randomized trial422 participantsCardiovascular Support forFish Oil
  41. Effect of High-Dose Marine Omega-3 Fatty Acids on Atherosclerosis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Sekikawa A; Cui C; Sugiyama D; Fabio A; Harris WS; Zhang X · Nutrients · 2020
    Meta-analysis6 studies pooledCardiovascular Support forFish Oil
  42. Vitamin C may reduce troponin and CKMB levels after PCI and CABG: a meta-analysis.
    Rozemeijer S; Hemilä H; van Baaren M; de Man AME · BMC cardiovascular disorders · 2023
    Meta-analysis872 participants7 studies pooledCardiovascular Support forVitamin C
  43. Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension.
    Taddei S; Virdis A; Ghiadoni L; Magagna A; Salvetti A · Circulation · 1998
    Clinical trial49 participantsCardiovascular Support forVitamin C
  44. Vitamin C supplementation improves blood pressure and oxidative stress after acute exercise in patients with poorly controlled type 2 diabetes mellitus: A randomized, placebo-controlled, cross-over study.
    Boonthongkaew C; Tong-Un T; Kanpetta Y; Chaungchot N; Leelayuwat C; Leelayuwat N · The Chinese journal of physiology · 2021
    Randomized trial24 participantsCardiovascular Support forVitamin C
  45. Vascular benefits of vitamin C supplementation against fine particulate air pollution in healthy adults: A double-blind randomised crossover trial.
    Ren J; Liang J; Wang J; Yin B; Zhang F; Li X; Zhu S; Tian H; Cui Q; Song J; Liu G; Ling W; Ma Y · Ecotoxicology and environmental safety · 2022
    Randomized trial58 participantsCardiovascular Support forVitamin C
  46. Ascorbic acid reduces blood pressure and arterial stiffness in type 2 diabetes.
    Mullan BA; Young IS; Fee H; McCance DR · Hypertension (Dallas, Tex. : 1979) · 2003
    Randomized trial30 participantsCardiovascular Support forVitamin C
  47. Efficacy of ginkgo diterpene lactone meglumine on cognitive function in patients with acute ischemic stroke: a predefined exploratory analysis of a multicenter, double-blind, randomized controlled trial.
    Tian X; Xu Q; Xia X; Zhang Y; Meng X; Wang A · Journal of neurology · 2024
    Randomized trial3,163 participantsCognitive Support forGinkgo
  48. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group.
    Le Bars PL; Katz MM; Berman N; Itil TM; Freedman AM; Schatzberg AF · JAMA · 1997
    Randomized trial309 participantsCognitive Support Productivity Boost forGinkgo
  49. Alleviating neuropsychiatric symptoms in dementia: the effects of Ginkgo biloba extract EGb 761. Findings from a randomized controlled trial.
    Bachinskaya N; Hoerr R; Ihl R · Neuropsychiatric disease and treatment · 2011
    Randomized trial410 participantsCognitive Support forGinkgo
  50. Efficacy and safety of a once-daily formulation of Ginkgo biloba extract EGb 761 in dementia with neuropsychiatric features: a randomized controlled trial.
    Ihl R; Bachinskaya N; Korczyn AD; Vakhapova V; Tribanek M; Hoerr R; Napryeyenko O; GOTADAY Study Group · International journal of geriatric psychiatry · 2013
    Randomized trial410 participantsCognitive Support forGinkgo
  51. Ginkgo biloba Extract EGb 761 in the Treatment of Patients with Mild Neurocognitive Impairment: A Systematic Review.
    Hort J; Duning T; Hoerr R · Neuropsychiatric disease and treatment · 2023
    Systematic review946 participants9 studies pooledMental Focus forGinkgo
  52. Proof of efficacy of the Ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia.
    Kanowski S; Herrmann WM; Stephan K; Wierich W; Hörr R · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
    Randomized trial216 participantsMental Focus forGinkgo
  53. Proof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia.
    Kanowski S; Herrmann WM; Stephan K; Wierich W; Hörr R · Pharmacopsychiatry · 1996
    Randomized trial216 participantsMental Focus forGinkgo
  54. Ginkgo biloba extract improved cognitive and neurological functions of acute ischaemic stroke: a randomised controlled trial.
    Li S; Zhang X; Fang Q; Zhou J; Zhang M; Wang H; Chen Y; Xu B; Wu Y; Qian L; Xu Y · Stroke and vascular neurology · 2021
    Randomized trial348 participantsMental Focus forGinkgo
  55. Ginkgo biloba in the Aging Process: A Narrative Review.
    Barbalho SM; Direito R; Laurindo LF; Marton LT; Guiguer EL; Goulart RA; Tofano RJ; Carvalho ACA; Flato UAP; Capelluppi Tofano VA; Detregiachi CRP; Bueno PCS; Girio RSJ; Araújo AC · Antioxidants (Basel, Switzerland) · 2024
    Narrative review14 studies pooledMental Focus forGinkgo
  56. [Ginkgo biloba extract EGb 761 in the treatment of dementia: evidence of efficacy and tolerability].
    Kasper S; Schubert H · Fortschritte der Neurologie-Psychiatrie · 2009
    Meta-analysis10 studies pooledProductivity Boost forGinkgo
  57. Dietary Flavonoids and Human Cognition: A Meta-Analysis.
    Cheng N; Bell L; Lamport DJ; Williams CM · Molecular nutrition & food research · 2022
    Meta-analysis5,519 participants80 studies pooledProductivity Boost forGinkgo
  58. Limited cognitive benefits in Stage +2 postmenopausal women after 6 weeks of treatment with Ginkgo biloba.
    Elsabagh S; Hartley DE; File SE · Journal of psychopharmacology (Oxford, England) · 2005
    Randomized trial87 participantsProductivity Boost forGinkgo
  59. Efficacy and safety of Ginkgo biloba extract EGb 761 in mild cognitive impairment with neuropsychiatric symptoms: a randomized, placebo-controlled, double-blind, multi-center trial.
    Gavrilova SI; Preuss UW; Wong JW; Hoerr R; Kaschel R; Bachinskaya N; GIMCIPlus Study Group · International journal of geriatric psychiatry · 2015
    Randomized trial160 participantsProductivity Boost forGinkgo
  60. Modulation of cognitive performance following single doses of 120 mg Ginkgo biloba extract administered to healthy young volunteers.
    Kennedy DO; Jackson PA; Haskell CF; Scholey AB · Human psychopharmacology · 2008
    Randomized trial78 participantsProductivity Boost forGinkgo
  61. DHA supplementation improved both memory and reaction time in healthy young adults: a randomized controlled trial.
    Stonehouse W; Conlon CA; Podd J; Hill SR; Minihane AM; Haskell C; Kennedy D · The American journal of clinical nutrition · 2013
    Randomized trial176 participantsProductivity Boost forOmega-3
  62. Effects of supplementation with n-3 polyunsaturated fatty acids on cognitive performance and cardiometabolic risk markers in healthy 51 to 72 years old subjects: a randomized controlled cross-over study.
    Nilsson A; Radeborg K; Salo I; Björck I · Nutrition journal · 2013
    Randomized trial40 participantsProductivity Boost forOmega-3
  63. Supplementation with oil rich in eicosapentaenoic acid, but not in docosahexaenoic acid, improves global cognitive function in healthy, young adults: results from randomized controlled trials.
    Patan MJ; Kennedy DO; Husberg C; Hustvedt SO; Calder PC; Khan J; Forster J; Jackson PA · The American journal of clinical nutrition · 2021
    Randomized trial310 participantsProductivity Boost forOmega-3
  64. Clinical significance of neuropsychological improvement after supplementation with omega-3 in 8-12 years old malnourished Mexican children: a randomized, double-blind, placebo and treatment clinical trial.
    Portillo-Reyes V; Pérez-García M; Loya-Méndez Y; Puente AE · Research in developmental disabilities · 2014
    Randomized trial59 participantsProductivity Boost forOmega-3
  65. Effects of seafood consumption and toenail mercury and selenium levels on cognitive function among American adults: 25 y of follow up.
    Mao X; Chen C; Xun P; Daviglus M; Steffen LM; Jacobs DR; Van Horn L; Sidney S; Zhu N; He K · Nutrition (Burbank, Los Angeles County, Calif.) · 2020
    Cohort study3,231 participantsProductivity Boost forOmega-3
  66. Effect of Ginkgo biloba extract on preexisting visual field damage in normal tension glaucoma.
    Quaranta L; Bettelli S; Uva MG; Semeraro F; Turano R; Gandolfo E · Ophthalmology · 2003
    Randomized trial27 participantsVision Support forGinkgo
  67. [Ginkgo extract in impaired vision--treatment with special extract EGb 761 of impaired vision due to dry senile macular degeneration].
    Fies P; Dienel A · Wiener medizinische Wochenschrift (1946) · 2002
    Randomized trial99 participantsVision Support forGinkgo
  68. Short-term effects of Ginkgo biloba extract on peripapillary retinal blood flow in normal tension glaucoma.
    Park JW; Kwon HJ; Chung WS; Kim CY; Seong GJ · Korean journal of ophthalmology : KJO · 2012
    Randomized trial30 participantsVision Support forGinkgo
  69. [The course of color vision in early diabetic retinopathy treated with Ginkgo biloba extract. A preliminary double-blind versus placebo study].
    Lanthony P; Cosson JP · Journal francais d'ophtalmologie · 1989
    Randomized trial29 participantsVision Support forGinkgo
  70. Antioxidant vitamin and mineral supplements for age-related macular degeneration.
    Evans JR · The Cochrane database of systematic reviews · 2002
    Systematic review170 participants7 studies pooledVision Support forZinc
  71. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2023
    Meta-analysis3,790 participants5 studies pooledVision Support forZinc
  72. Oral zinc in macular degeneration.
    Newsome DA; Swartz M; Leone NC; Elston RC; Miller E · Archives of ophthalmology (Chicago, Ill. : 1960) · 1988
    Randomized trial151 participantsVision Support forZinc
  73. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
    Age-Related Eye Disease Study Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2001
    Randomized trial3,640 participantsVision Support forZinc
  74. Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand.
    Udomkesmalee E; Dhanamitta S; Sirisinha S; Charoenkiatkul S; Tuntipopipat S; Banjong O; Rojroongwasinkul N; Kramer TR; Smith JC · The American journal of clinical nutrition · 1992
    Randomized trial133 participantsVision Support forZinc