Product Image

Higher Mind

Source Naturals
4.4
★ ★ ★ ★ ★
(210 ratings)
Vinpocetine 30 mg
Acetyl L-Carnitine 500 mg
Huperzine 200 mcg
Manganese 5 mg
Deanol 160 mg
GABA 100 mg
Vitamin B5 100 mg
Product Image
Score61
A deep cognitive stack with meaningful phosphatidylserine, carnitine, tyrosine, ginkgo, and huperzine A. Extreme B6 and niacin plus vinpocetine and broad interaction risk outweigh much of that depth.
How scoring works
Quantity:90 Tablet(s) • (22 servings)
Goals:
Mental Focus
Productivity Boost
Brain Health
Cognitive Support
Anti-Aging
Energy
Mood Support
Stress Relief

Score 61

A deep cognitive stack with meaningful phosphatidylserine, carnitine, tyrosine, ginkgo, and huperzine A. Extreme B6 and niacin plus vinpocetine and broad interaction risk outweigh much of that depth.
How scoring works
$29.81($1.35 per serving)
iHerb
$ 47.61
Amazon
$ 29.81
Vitacost
$ 47.61
Report prices

Analysis

The formula covers membrane support, acetylcholine signaling, amino-acid precursors, cerebral circulation, stress response, and cellular energy. Phosphatidylserine, acetyl-L-carnitine, gotu kola, tyrosine, ginkgo, alpha-lipoic acid, and huperzine A are the most relevant cognitive ingredients.

Many active weights are substantial, but extract standardization is incomplete and several duplicate nutrient lines make actual totals difficult to read. Vitamin B6, niacin, and folate are especially aggressive, while basic cyanocobalamin is used despite the premium complexity.

Only experienced users who can screen medicines and health conditions should consider this stack. Pregnancy, anticoagulant use, cholinergic medicines, liver concerns, and long-term unsupervised use are poor fits.

Who is it for
  • Experienced supplement users seeking multi-pathway cognitive support
  • Adults able to review medication interactions carefully
Best for
  • Broad cognitive pathway coverage
  • Combining membrane, circulation, precursor, and cholinergic support

Pros

  • Meaningful phosphatidylserine and acetyl-L-carnitine
  • Includes ginkgo, tyrosine, and huperzine A
  • Broad cognitive mechanism coverage
  • Most active weights are disclosed

Cons

  • Vitamin B6 and niacin are extremely high
  • Four-tablet serving
  • Extract standardization is incomplete
  • Duplicate nutrient lines reduce clarity
  • High interaction burden

Warnings

  • Vinpocetine should not be used during pregnancy because it may harm fetal development.
  • Vitamin B6 at 100 mg may cause nerve symptoms with repeated use.
  • Niacin at 164 mg may cause flushing and may affect liver or glucose management.
  • Ginkgo may increase bleeding risk with anticoagulant or antiplatelet medicines.
  • Huperzine A may interact with cholinergic or anticholinergic medicines and can cause nausea, vivid dreams, or a slow heart rate.

Nutrient quality

60 Moderate impact

Phosphatidylserine, acetyl-L-carnitine, magnesium malate, and active B6 provide several useful forms. The apparent B6 total is extremely high, and high niacin plus potent neurological actives make the formula aggressive.

Ingredient transparency

70 High impact

Every listed active has an amount, though duplicate vitamin entries make some totals ambiguous. No proprietary blend hides a listed active dose; daily directions and a complete inactive-ingredient list are not supplied.

Customer satisfaction

58 Moderate impact

The supplied rating is mixed to favorable, with limited volume behind it. Detailed feedback themes are absent, leaving repeated complaints and purpose fit uncertain.

Value for money

52 Moderate impact

Many meaningful cognitive actives partly justify the premium. The serving cost is high for a formula with major long-term dosing concerns.

Report analysis

Goals

Mental Focus
Mental Focus
Impact
Highest effect
A- Goal FitB+ Strength of SupportA CoverageB Formula Quality
Folate · 1360 mcg DFEVitamin B6 · 100 mgVitamin B12 · 400 mcgMagnesium · 200 mgAcetyl L-Carnitine · 500 mgHuperzine · 200 mcg

Acetyl-L-carnitine, phosphatidylserine, ginkgo, huperzine A, vinpocetine, and tyrosine make this a highly relevant nootropic formula. Several lead ingredients reach useful amounts, though extract standardization and some precursor doses remain imperfect.

The wide stack covers cognitive energy, cholinergic signaling, circulation, stress response, and neurotransmitter production. Ginkgo and vinpocetine may matter with blood-thinning medicines, huperzine A can interact with cholinergic drugs, phenylalanine is unsuitable for phenylketonuria, and the high B6 amount may raise neuropathy risk with prolonged use.

Study evidence
Acetyl L-Carnitine Supportive 7 studies
Ginkgo Supportive 28 studies
Huperzine Not classified

No linked studies yet.

Phenylalanine No effect 7 studies
Vinpocetine Supportive 3 studies
Productivity Boost
Productivity Boost
Impact
Highest effect
A- Goal FitB Strength of SupportA- CoverageB- Formula Quality
Vitamin B12 · 400 mcgVitamin B12 · 400 mcgVitamin B6 · 100 mgZinc · 10 mgMagnesium · 200 mgAcetyl L-Carnitine · 500 mgAcetyl L-Carnitine · 500 mgEleuthero · 60 mgEleuthero · 60 mgVinpocetine · 30 mgHuperzine · 200 mcg

Acetyl-L-carnitine, phosphatidylserine, ginkgo, vinpocetine, huperzine A, tyrosine, and adaptogens directly target cognitive energy and focus. Acetyl-L-carnitine, phosphatidylserine, ginkgo, vinpocetine, and huperzine A reach meaningful disclosed amounts.

The formula covers cellular energy, membrane support, cholinergic signaling, circulation, neurotransmitter precursors, and stress response. Most major pathways receive useful amounts, though some amino acids and adaptogens are comparatively light.

Study evidence
Acetyl L-Carnitine Supportive 1 study
Acetyl L-Carnitine Supportive 1 study
Ginkgo Supportive 20 studies
Ginkgo Supportive 12 studies
Huperzine No effect 1 study
Brain Health
Brain Health
Impact
High effect
A- Goal FitB Strength of SupportA- CoverageC Formula Quality
Folate · 1360 mcg DFEVitamin B12 · 400 mcgVitamin B6 · 100 mgThiamin · 100 mgMagnesium · 200 mgAshwagandha · 100 mgHuperzine · 200 mcg

Phosphatidylserine, acetyl L-carnitine, ginkgo, vinpocetine, and huperzine A provide strong coverage of membrane health, energy metabolism, circulation, and cholinergic signaling. Several central actives reach useful amounts, although ginkgo and botanical standardization remain incomplete.

The formula has unusually broad cognitive depth but also includes many lower-priority vitamins, amino acids, and botanicals. The high B6 amount raises chronic stacking concerns, while ginkgo, vinpocetine, and huperzine A may interact with blood-thinning or cholinergic medicines.

Study evidence
Acetyl L-Carnitine Supportive 19 studies
Ginkgo Supportive 90 studies
Huperzine Supportive 17 studies
Vinpocetine Supportive 7 studies
Cognitive Support
Cognitive Support
Impact
High effect
B+ Goal FitB Strength of SupportA- CoverageC Formula Quality
Thiamin · 100 mgVitamin B6 · 100 mgFolate · 1360 mcg DFEVitamin B12 · 400 mcgMagnesium · 200 mgHuperzine · 200 mcgAshwagandha · 100 mgAcetyl L-Carnitine · 500 mg

Acetyl-L-carnitine, phosphatidylserine, tyrosine, ginkgo, DMAE, vinpocetine, and huperzine A cover energy, membranes, neurotransmitters, and cerebral circulation. Several amounts are clinically plausible, though multiple extracts lack standardization and some evidence is stronger for specific populations than routine enhancement.

The stack is broad and mostly complementary, but its 41 ingredients make the active contribution difficult to isolate. The 100 mg B6 amount raises neuropathy risk with long-term use, while ginkgo and vinpocetine matter with blood thinners and huperzine A can interact with cholinergic or anticholinergic medicines.

Study evidence
Acetyl L-Carnitine Supportive 20 studies
Ginkgo Supportive 87 studies
Huperzine Supportive 22 studies
Anti-Aging
Anti-Aging
Impact
High effect
B+ Goal FitB Strength of SupportB+ CoverageC- Formula Quality
Folate · 1360 mcg DFEMagnesium · 200 mgVitamin B12 · 400 mcgTaurine · 100 mg

Acetyl-L-carnitine, phosphatidylserine, alpha-lipoic acid, ginkgo, gotu kola, and active B vitamins target cognitive and mitochondrial aspects of aging. Antioxidants and adaptogens broaden coverage to oxidative stress and resilience.

The extensive formula contains many modest secondary actives and some less favorable vitamin forms. Vinpocetine is a concern for anyone pregnant or who could become pregnant, while 100 mg pyridoxine raises long-term nerve-symptom risk.

Study evidence
Acetyl L-Carnitine Supportive 1 study
Magnesium Supportive 12 studies
Energy
Energy
Impact
High effect
B+ Goal FitB Strength of SupportA- CoverageD+ Formula Quality
Vitamin B5 · 100 mgMagnesium · 200 mgRiboflavin · 50 mgThiamin · 100 mgVitamin B12 · 400 mcgAcetyl L-Carnitine · 500 mg

Acetyl-L-carnitine, magnesium, high-potency B vitamins, tyrosine, phosphatidylserine, and alpha-lipoic acid cover metabolic and cognitive-energy pathways. Several focus ingredients reach meaningful amounts without relying on caffeine.

The very large formula includes many modest or unstandardized botanicals, which makes the depth uneven. Ginkgo and vinpocetine may matter with anticoagulant or antiplatelet medicines, while huperzine A can interact with cholinergic or anticholinergic drugs.

Study evidence
Acetyl L-Carnitine Supportive 19 studies
Magnesium Supportive 4 studies
Thiamin Disputed 12 studies

Ingredients

IngredientAmount per serving
Calories
15 Calorie(s)
Total Carbohydrate
1 Gram(s)
Vitamin C (Ascorbic Acid, Zinc Ascorbate)
 200 mg
Thiamine (Vitamin B1)
 100 mg
Riboflavin (Vitamin B2)
 50 mg
Niacin
164 mg
Vitamin B6 (Pyridoxal-5'-Phosphate, Pyridoxine Hydrochloride)
 100 mg
Folate (Calcium Folinate, Folic Acid)
 1360 mcg DFE
Vitamin B12 (Cyanocobalamin)
 400 mcg
Biotin
80 mcg
Pantothenic Acid (Calcium D-Pantothenate)
 100 mg
Magnesium (Magnesium Malate, Magnesium Oxide)
 200 mg
Zinc (Zinc Ascorbate)
 10 mg
Manganese (Manganese Citrate)
 5 mg
Sodium
5 mg
L-Pyroglutamic Acid
600 mg
L-Glutamine
500 mg
Acetyl L-Carnitine HCl
500 mg
Gotu Kola Whole Plant Extract
250 mg
Phosphatidylserine
200 mg
N-Acetyl L-Tyrosine
200 mg
DMAE (DMAE Bitartrate)
 160 mg
Ginkgo leaf extract
120 mg
Inositol Nicotinate
110 mg
Alpha-Lipoic Acid
100 mg
Taurine
100 mg
DL-Phenylalanine
100 mg
GABA
100 mg
L-Phenylalanine
100 mg
Gamma-Vitamin E Complex
100 mg
Ashwagandha root ext.
100 mg
Turmeric
100 mg
Bilberry fruit extract
100 mg
Eleuthero root extract
60 mg
Vinpocetine
30 mg
Boron (Boron Amino Acid Complex)
 2 mg
Huperzine A (Huperzia serrata whole plant extract)
 200 mcg
Adults 18–50 Women
Report overview
Vinpocetine · 30 mg OverallScore92
A Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

The clearly disclosed vinpocetine amount sits at the top of the standard target range. A single-tablet serving is convenient, although the provided data does not fully detail inactive ingredients. Cost efficiency is only moderate for vinpocetine alone, but substantial doses of phosphatidylserine, acetyl-L-carnitine, and ginkgo add meaningful value to the broader stack.

View ingredientView products
Acetyl L-Carnitine · 500 mg OverallScore79
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The formula delivers a clearly disclosed, target-range dose of ALCAR hydrochloride alongside phosphatidylserine and other cognitive ingredients. Its broad blend partly explains the high cost per useful ALCAR amount, though it is not efficient for someone seeking ALCAR alone. Ginkgo and vinpocetine can matter for people using anticoagulant or antiplatelet medicines, while huperzine A can interact with cholinergic or anticholinergic drugs.

View ingredientView products
Huperzine (Huperzia serrata whole plant extract) · 200 mcg OverallScore77
B+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD+ Value

The disclosed 200 mcg dose of Huperzine A sits at the upper end of the intended range and comes in a precise tablet format. Huperzia serrata whole plant extract is named, but the label does not confirm a standardized alkaloid percentage. The broader nootropic formula adds useful context, while moderate active-cost efficiency and absent cycling guidance remain meaningful trade-offs.

View ingredientView products
Loading alternative details
74 Performance

Stress B-Complex

Thorne
<p>Methylcobalamin, choline citrate, and substantial pantothenic acid create a coherent stress-oriented B complex. Compared with the original, the clearer or more purposeful core improves ingredient quality and usability; however, high B6 and niacin plus several unspecified forms make routine long-term use less appealing.</p>
76 Performance

B Complex

INNATE Response Formulas
<p>Moderate B-vitamin amounts and food-derived carriers create a less aggressive profile than many high-dose complexes. Compared with the original, the clearer or more purposeful core improves ingredient quality and usability; however, pyridoxine and cyanocobalamin are conventional forms and the serving cost is relatively high for the category.</p>
73 Performance

B-50 Gels

Carlson
<p>A full B-complex is clearly dosed and keeps the formula simpler than a multi-ingredient cognitive stack. Compared with the original, the clearer or more purposeful core improves ingredient quality and usability; however, conventional forms and high B6 still make daily long-term use unnecessarily aggressive.</p>
78 Budget

B-50 Complex

21st Century
<p>A clearly disclosed B-complex supplies substantial core B vitamins in a long, inexpensive supply. Its lower serving cost improves affordability compared with the original, although conventional forms and high vitamin B6 reduce its fit for unsupervised long-term use.</p>
74 Budget

B 50 Complex

Spring Valley
<p>A low-cost formula supplies substantial amounts of the core B vitamins. Its lower serving cost improves affordability compared with the original, although missing chemical forms and high B6 make absorption, flushing potential, and long-term safety harder to assess.</p>
71 Budget

B 50 Complex

Thompson
<p>A broad B-complex supplies substantial core B vitamins with favorable serving economics. Its lower serving cost improves affordability compared with the original, although conventional forms, an undisclosed base blend, and sustained high B6 weaken transparency and long-term suitability.</p>
79 Value

B-100 Complex

21st Century
<p>A broad high-potency B profile covers the core vitamins at a low serving cost. The ingredient profile and serving economics offer a stronger quality-to-cost balance than the original, although mostly conventional forms and B6 at the chronic-use safety ceiling weaken its suitability for daily use.</p>
77 Value

B-50 Complex

Nature's Way
<p>Active riboflavin improves a broad and clearly dosed B-complex base. The ingredient profile and serving economics offer a stronger quality-to-cost balance than the original, although the high B6 amount can be difficult to justify for sustained daily use.</p>
77 Value

Vitamin B Complex

California Gold Nutrition
<p>Active riboflavin and vitamin B6 forms improve a compact B-complex with pantothenic acid and folate. The ingredient profile and serving economics offer a stronger quality-to-cost balance than the original, although duplicate niacin, B6, and biotin entries obscure total exposure and B6 may still be high for sustained use.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Efficacy of Ginkgo biloba extract EGb 761® in dementia with behavioural and psychological symptoms: A systematic review.
    von Gunten A; Schlaefke S; Überla K · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2017
    Meta-analysis1,628 participants4 studies pooledCognitive Support Brain Health forGinkgo
  2. Ginkgo biloba for cognitive impairment and dementia.
    Wieland LS; Ludeman E; Chi Y; Feinberg TM; Chen IH; Chen KH; Zhu Y; Wolverson E; Amri H · The Cochrane database of systematic reviews · 2026
    Meta-analysis10,613 participants82 studies pooledCognitive Support forGinkgo
  3. Acetyl-L-carnitine treatment in minimal hepatic encephalopathy.
    Malaguarnera M; Gargante MP; Cristaldi E; Vacante M; Risino C; Cammalleri L; Pennisi G; Rampello L · Digestive diseases and sciences · 2008
    Randomized trial125 participantsCognitive Support Brain Health forAcetyl L-Carnitine
  4. A 1-year controlled trial of acetyl-l-carnitine in early-onset AD.
    Thal LJ; Calvani M; Amato A; Carta A · Neurology · 2000
    Randomized trial229 participantsCognitive Support forAcetyl L-Carnitine
  5. Adjunctive huperzine A for cognitive deficits in schizophrenia: a systematic review and meta-analysis.
    Zheng W; Xiang YQ; Li XB; Ungvari GS; Chiu HF; Sun F; D'Arcy C; Meng X; Xiang YT · Human psychopharmacology · 2017
    Meta-analysis1,117 participants12 studies pooledCognitive Support forHuperzine
  6. A phase II trial of huperzine A in mild to moderate Alzheimer disease.
    Rafii MS; Walsh S; Little JT; Behan K; Reynolds B; Ward C; Jin S; Thomas R; Aisen PS; Alzheimer's Disease Cooperative Study · Neurology · 2011
    Randomized trial210 participantsCognitive Support forHuperzine
  7. Acetyl-L-carnitine Slows the Progression from Prefrailty to Frailty in Older Subjects: A Randomized Interventional Clinical Trial.
    Malaguarnera G; Catania VE; Bertino G; Chisari LM; Castorina M; Bonfiglio C; Cauli O; Malaguarnera M · Current pharmaceutical design · 2022
    Randomized trial92 participantsAnti-Aging forAcetyl L-Carnitine
  8. Dietary Magnesium May Be Protective for Aging of Bone and Skeletal Muscle in Middle and Younger Older Age Men and Women: Cross-Sectional Findings from the UK Biobank Cohort.
    Welch AA; Skinner J; Hickson M · Nutrients · 2018
    Cross-sectional study156,575 participantsAnti-Aging forMagnesium
  9. Higher Magnesium Intake Is Associated with a Lower Risk of Frailty in Older Adults.
    Dominguez LJ; Mérida DM; Donat-Vargas C; Banegas JR; Veronese N; Barbagallo M; Rodríguez-Artalejo F; Guallar-Castillón P · Journal of the American Medical Directors Association · 2024
    Cohort study1,900 participantsAnti-Aging forMagnesium
  10. Ca:Mg Ratio, APOE Cytosine Modifications, and Cognitive Function: Results from a Randomized Trial.
    Zhu X; Borenstein AR; Zheng Y; Zhang W; Seidner DL; Ness R; Murff HJ; Li B; Shrubsole MJ; Yu C; Hou L; Dai Q · Journal of Alzheimer's disease : JAD · 2021
    Randomized trial250 participantsAnti-Aging forMagnesium
  11. The Association between Dietary Nutrient Intake and Acceleration of Aging: Evidence from NHANES.
    Ma J; Li P; Jiang Y; Yang X; Luo Y; Tao L; Guo X; Gao B · Nutrients · 2024
    Cross-sectional study4,692 participantsAnti-Aging forMagnesium
  12. Interpretable machine learning with SHAP analysis identifies redox-modulating dietary antioxidants for predicting accelerated biological aging.
    Zhang B; Zhang X; Ma L; Li D; Li Y; Lin S; Peng L; He L · Experimental gerontology · 2026
    Cross-sectional study8,125 participantsAnti-Aging forMagnesium
  13. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  14. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  15. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  16. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  17. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  18. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  19. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  20. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  21. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  22. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  23. Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES.
    Ling R; Ai Y; Chen C; Zhang J; Zou Z; Cheng S; Li C; Li X; Wang B · Metabolites · 2023
    Cross-sectional study2,640 participantsBone Health forManganese
  24. The Manganese-Bone Connection: Investigating the Role of Manganese in Bone Health.
    Taskozhina G; Batyrova G; Umarova G; Issanguzhina Z; Kereyeva N · Journal of clinical medicine · 2024
    Narrative reviewBone Health forManganese
  25. Associations of multiple metals with bone mineral density: A population-based study in US adults.
    Wei MH; Cui Y; Zhou HL; Song WJ; Di DS; Zhang RY; Huang Q; Liu JA; Wang Q · Chemosphere · 2021
    Cross-sectional studyBone Health forManganese
  26. Sex-specific associations of urinary mixed-metal concentrations with femoral bone mineral density among older people: an NHANES (2017-2020) analysis.
    Li H; Li G; Yi M; Zhou J; Deng Y; Huang Y; He S; Meng X; Liu L · Frontiers in public health · 2024
    Cross-sectional study31 participantsBone Health forManganese
  27. Relationship between blood manganese and bone mineral density and bone mineral content in adults: A population-based cross-sectional study.
    Wang C; Zhu Y; Long H; Ou M; Zhao S · PloS one · 2022
    Cross-sectional study9,732 participantsBone Health forManganese
  28. Can Dietary Intake of Vitamin C-Oriented Foods Reduce the Risk of Osteoporosis, Fracture, and BMD Loss? Systematic Review With Meta-Analyses of Recent Studies.
    Zeng LF; Luo MH; Liang GH; Yang WY; Xiao X; Wei X; Yu J; Guo D; Chen HY; Pan JK; Huang HT; Liu Q; Guan ZT; Han YH; Zhao D; Zhao JL; Hou SR; Wu M; Lin JT; Li JH; Liang WX; Ou AH; Wang Q; Li ZP; Liu J · Frontiers in endocrinology · 2020
    Meta-analysis19,484 participants17 studies pooledBone Health forVitamin C
  29. Dietary vitamin C intake and the risk of hip fracture: a dose-response meta-analysis.
    Sun Y; Liu C; Bo Y; You J; Zhu Y; Duan D; Cui H; Lu Q · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Meta-analysis6 studies pooledBone Health forVitamin C
  30. Smoking, antioxidant vitamins, and the risk of hip fracture.
    Melhus H; Michaëlsson K; Holmberg L; Wolk A; Ljunghall S · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1999
    Cohort study66,651 participantsBone Health forVitamin C
  31. Micronutrients and the risk of hip fracture: Case-control study.
    Torbergsen AC; Watne LO; Wyller TB; Frihagen F; Strømsøe K; Bøhmer T; Mowe M · Clinical nutrition (Edinburgh, Scotland) · 2018
    Case-control study189 participantsBone Health forVitamin C
  32. Favorable effect of dietary vitamin C on bone mineral density in postmenopausal women (KNHANES IV, 2009): discrepancies regarding skeletal sites, age, and vitamin D status.
    Kim YA; Kim KM; Lim S; Choi SH; Moon JH; Kim JH; Kim SW; Jang HC; Shin CS · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Cross-sectional study1,196 participantsBone Health forVitamin C
  33. Long-term acetyl-L-carnitine treatment in Alzheimer's disease.
    Spagnoli A; Lucca U; Menasce G; Bandera L; Cizza G; Forloni G; Tettamanti M; Frattura L; Tiraboschi P; Comelli M · Neurology · 1991
    Randomized trial130 participantsBrain Health Cognitive Support forAcetyl L-Carnitine
  34. Pharmaco-electroencephalographic and clinical effects of the cholinergic substance--acetyl-L-carnitine--in patients with organic brain syndrome.
    Herrmann WM; Dietrich B; Hiersemenzel R · International journal of clinical pharmacology research · 1990
    Randomized trialBrain Health forAcetyl L-Carnitine
  35. Acetyl-L-carnitine improves cognitive functions in severe hepatic encephalopathy: a randomized and controlled clinical trial.
    Malaguarnera M; Vacante M; Motta M; Giordano M; Malaguarnera G; Bella R; Nunnari G; Rampello L; Pennisi G · Metabolic brain disease · 2012
    Randomized trial61 participantsBrain Health Cognitive Support forAcetyl L-Carnitine
  36. Acetyl-L-carnitine in the treatment of mildly demented elderly patients.
    Passeri M; Cucinotta D; Bonati PA; Iannuccelli M; Parnetti L; Senin U · International journal of clinical pharmacology research · 1990
    Randomized trial60 participantsBrain Health Mental Focus forAcetyl L-Carnitine
  37. Efficacy and adverse effects of ginkgo biloba for cognitive impairment and dementia: a systematic review and meta-analysis.
    Tan MS; Yu JT; Tan CC; Wang HF; Meng XF; Wang C; Jiang T; Zhu XC; Tan L · Journal of Alzheimer's disease : JAD · 2015
    Meta-analysis2,561 participants9 studies pooledBrain Health forGinkgo
  38. Ginkgo biloba extract EGb 761 is safe and effective in the treatment of mild dementia - a meta-analysis of patient subgroups in randomised controlled trials.
    Riepe M; Hoerr R; Schlaefke S · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2025
    Meta-analysis782 participants4 studies pooledBrain Health Productivity Boost forGinkgo
  39. Ginkgo biloba extract EGb 761® improves cognition and overall condition after ischemic stroke: Results from a pilot randomized trial.
    Cui M; You T; Zhao Y; Liu R; Guan Y; Liu J; Liu X; Wang X; Dong Q · Frontiers in pharmacology · 2023
    Randomized trial201 participantsBrain Health Productivity Boost forGinkgo
  40. Ginkgo biloba extract EGb 761® in dementia with neuropsychiatric features: a randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of 240 mg.
    Herrschaft H; Nacu A; Likhachev S; Sholomov I; Hoerr R; Schlaefke S · Journal of psychiatric research · 2012
    Randomized trial410 participantsBrain Health forGinkgo
  41. Huperzine a in the treatment of Alzheimer's disease and vascular dementia: a meta-analysis.
    Xing SH; Zhu CX; Zhang R; An L · Evidence-based complementary and alternative medicine : eCAM · 2014
    Meta-analysis825 participants10 studies pooledBrain Health Cognitive Support forHuperzine
  42. [Clinical efficacy and safety of huperzine Alpha in treatment of mild to moderate Alzheimer disease, a placebo-controlled, double-blind, randomized trial].
    Zhang Z; Wang X; Chen Q; Shu L; Wang J; Shan G · Zhonghua yi xue za zhi · 2002
    Randomized trial202 participantsBrain Health Cognitive Support forHuperzine
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    Wang J; Liu G; Xu K; Ai K; Huang W; Zhang J · Human brain mapping · 2023
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    Walyddaini AS; Lisal ST; Ilhamuddin; Zainuddin AA; Tanra AJ; Widianingsih Y; Syamsuddin S · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
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    Islam MR; Ali S; Karmoker JR; Kadir MF; Ahmed MU; Nahar Z; Islam SMA; Islam MS; Hasnat A; Islam MS · BMC psychiatry · 2020
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    Beckmann H; Ludolph E · Arzneimittel-Forschung · 1979
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    Khodadad M; Bahadoran P; Kheirabadi GR; Sabzghabaee AM · International journal of preventive medicine · 2022
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    Observational study17,732 participantsMood Support forVitamin B6
  150. Impact of vitamin B6 status on psychological distress in a longitudinal study of HIV-1 infection.
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    Meta-analysis10 studies pooledProductivity Boost forGinkgo
  152. Dietary Flavonoids and Human Cognition: A Meta-Analysis.
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    Meta-analysis5,519 participants80 studies pooledProductivity Boost forGinkgo
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  154. Efficacy and safety of Ginkgo biloba extract EGb 761 in mild cognitive impairment with neuropsychiatric symptoms: a randomized, placebo-controlled, double-blind, multi-center trial.
    Gavrilova SI; Preuss UW; Wong JW; Hoerr R; Kaschel R; Bachinskaya N; GIMCIPlus Study Group · International journal of geriatric psychiatry · 2015
    Randomized trial160 participantsProductivity Boost forGinkgo
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    Randomized trial78 participantsProductivity Boost forGinkgo
  156. Effect of Huperzine A on Cognitive Function and Perception of Effort during Exercise: A Randomized Double-Blind Crossover Trial.
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  157. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.
    Lopresti AL; Smith SJ; Malvi H; Kodgule R · Medicine · 2019
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  158. Shoden promotes Relief from stress and anxiety: A randomized, double-blind, placebo-controlled study on healthy subjects with high stress levels.
    Mishra DN; Kumar M · Heliyon · 2024
    Randomized trial60 participantsStress Relief forAshwagandha
  159. Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
    Gopukumar K; Thanawala S; Somepalli V; Rao TSS; Thamatam VB; Chauhan S · Evidence-based complementary and alternative medicine : eCAM · 2022
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    Salve J; Pate S; Debnath K; Langade D · Cureus · 2020
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  162. GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial.
    Guimarães AP; Seidel H; Pires LVM; Trindade CO; Baleeiro RDS; Souza PM; Silva FGDE; Coelho DB; Becker LK; Oliveira EC · Journal of dietary supplements · 2024
    Randomized trial30 participantsStress Relief forGABA
  163. Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid.
    Kanehira T; Nakamura Y; Nakamura K; Horie K; Horie N; Furugori K; Sauchi Y; Yokogoshi H · Journal of nutritional science and vitaminology · 2011
    Clinical trial30 participantsStress Relief forGABA
  164. Cortical gamma-aminobutyric acid and glutamate in posttraumatic stress disorder and their relationships to self-reported sleep quality.
    Meyerhoff DJ; Mon A; Metzler T; Neylan TC · Sleep · 2014
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  165. Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
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  166. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
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  173. Correlations between dietary taurine intake and life stress in Korean college students.
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    Observational studyStress Relief forTaurine
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  175. RENAL PROTECTIVE EFFECT AND CLINICAL ANALYSIS OF VITAMIN B 6 IN PATIENTS WITH SEPSIS.
    Wang Y; Lu WL; Feng WM; Xu W; Liu LH; He LM · Shock (Augusta, Ga.) · 2024
    Randomized trial128 participantsStress Relief forVitamin B6
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    Randomized trial264 participantsStress Relief forVitamin B6
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    Cross-sectional study447 participantsStress Relief forVitamin B6
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    Meta-analysis1,249 participants20 studies pooledTestosterone Support forAshwagandha
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    Randomized trial50 participantsTestosterone Support forAshwagandha
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    Systematic review32 studies pooledTestosterone Support forAshwagandha
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    Systematic review3 studies pooledTestosterone Support forAshwagandha
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    Vaidya N; Agarwal R; Kshirsagar P; Ganu G; Nagore D; Mehta A; Vora A; Nair S · Food science & nutrition · 2025
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    Nielsen FH · Environmental health perspectives · 1995
    Single-arm trial12 participantsTestosterone Support forBoron
  184. Plasma boron and the effects of boron supplementation in males.
    Green NR; Ferrando AA · Environmental health perspectives · 1995
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  185. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
    Mohammad Reza Naghii, Mahmoud Mofid, Ali Reza Asgari, Mehdi Hedayati, Maryam-Saddat Daneshpour · Journal of Trace Elements in Medicine and Biology · 2011
    Non-randomized trial8 participantsTestosterone Support forBoron
  186. Magnesium and anabolic hormones in older men.
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  187. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
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    Randomized trial64 participantsTestosterone Support forMagnesium
  189. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  190. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium
  191. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
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    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewTestosterone Support forZinc
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    Narrative reviewTestosterone Support forZinc
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    Fies P; Dienel A · Wiener medizinische Wochenschrift (1946) · 2002
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  199. Short-term effects of Ginkgo biloba extract on peripapillary retinal blood flow in normal tension glaucoma.
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    Randomized trial30 participantsVision Support forGinkgo
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  201. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
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    Randomized trial400 participantsVision Support forVitamin C
  202. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
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    Observational studyVision Support forVitamin C
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    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  204. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C Vision Support forVitamin E
  205. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
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    Case-control study883 participantsVision Support forVitamin C
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    Meta-analysis55,614 participants4 studies pooledVision Support forVitamin E
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    Evans JR · The Cochrane database of systematic reviews · 2002
    Systematic review170 participants7 studies pooledVision Support forZinc
  211. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2023
    Meta-analysis3,790 participants5 studies pooledVision Support forZinc
  212. Oral zinc in macular degeneration.
    Newsome DA; Swartz M; Leone NC; Elston RC; Miller E · Archives of ophthalmology (Chicago, Ill. : 1960) · 1988
    Randomized trial151 participantsVision Support forZinc
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    Randomized trial3,640 participantsVision Support forZinc
  214. Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand.
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    Randomized trial133 participantsVision Support forZinc