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Real Food K-2 200 mcg Maximum Strength

4.8
★ ★ ★ ★ ★
(667 ratings)
Vitamin K 200 mcg
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Score74
A potent MK-7 softgel with suitable delivery, held back by generic sourcing and high cost for a single active.
How scoring works
Softgel
Quantity:30 Softgel(s) • (30 servings)
Goals:
Bone Health
Heart Health
Cardiovascular Support
Anti-Aging
General Health

Score 74

A potent MK-7 softgel with suitable delivery, held back by generic sourcing and high cost for a single active.
How scoring works
$37.99($1.26 per serving)
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$ 37.99
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$ 37.99
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Analysis

The substantial MK-7 amount supports vitamin K-dependent proteins involved in bone mineral placement and arterial calcium handling. Softgel delivery suits this fat-soluble nutrient.

The formula does not identify a branded source or guarantee all-trans MK-7 purity. Its high serving cost is difficult to justify for a single generic active.

The product fits adults who deliberately want an upper-end K2 amount and prefer softgels. More economical options can provide similar focused support with better source disclosure.

Who is it for
  • Adults seeking an upper-end MK-7 amount
  • People who prefer softgels
  • Users wanting focused K2 without added nutrients
Best for
  • Bone-protein activation
  • Calcium placement
  • High-depth K2 supplementation

Pros

  • Substantial MK-7 amount
  • Softgel supports absorption
  • Simple one-ingredient formula

Cons

  • No branded or all-trans source claim
  • High serving cost
  • No complementary vitamin D or minerals

Warnings

  • MK-7 can oppose warfarin and related vitamin K antagonist medicines
  • Keep vitamin K intake consistent if anticoagulation therapy permits use
  • Avoid unnecessary duplication with other high-K2 supplements

Nutrient quality

92 Highest impact

Menaquinone-7 is a well-regarded, long-acting vitamin K2 form, and the vitamin K2 amount is substantial for a focused standalone supplement. The amount is fairly assertive but has no established toxicity concern for healthy adults, while the single-active formula is not padded with low-value ingredients.

Ingredient transparency

84 Highest impact

Specific amounts are listed for every supplied active ingredient. No proprietary blend hides active doses, while capsule, softgel, or tablet excipients are not included in the supplied details.

Customer satisfaction

71 High impact

The supplied aggregate satisfaction metric is very strong, and the feedback volume is sufficient for a reasonably stable aggregate metric. No review excerpts were provided, so recurring complaints and purpose-specific experiences cannot be checked.

Value for money

43 Lower impact

A focused formula and well-regarded vitamin K2 form support good value. Each serving provides a meaningful active amount with little burden, while the formula avoids unnecessary active extras.

Report analysis

Goals

Bone Health
Impact
Highest effect
A- Goal FitA+ Strength of SupportC+ CoverageA+ Formula Quality
Vitamin K · 200 mcg

MK-7 directly supports activation of osteocalcin, a protein involved in binding calcium to bone, and the 200 mcg amount sits within the preferred range. The softgel also provides a suitable lipid-based format for this fat-soluble vitamin.

The source is generic and lacks a branded or all-trans purity claim, so source quality is not fully defined. Vitamin K2 can interfere with warfarin and related vitamin K antagonists, requiring consistent intake and clinician-guided management for users of those medicines.

Study evidence
Vitamin K Supportive 78 studies
Heart Health
Impact
Highest effect
A- Goal FitA+ Strength of SupportC+ CoverageA+ Formula Quality
Vitamin K · 200 mcg

Vitamin K2 as MK-7 supports calcium placement and may contribute to arterial health. The 200 mcg amount is well aligned with commonly used MK-7 supplementation.

Softgel delivery suits this fat-soluble vitamin, though no branded all-trans source is stated. Vitamin K2 can interfere with warfarin and related vitamin K antagonists, so users of those medicines need managed, consistent vitamin K intake.

Study evidence
Vitamin K Mixed 62 studies
Cardiovascular Support
Impact
Highest effect
B+ Goal FitA+ Strength of SupportC- CoverageA+ Formula Quality
Vitamin K · 200 mcg

Vitamin K2 is provided as MK-7 at a well-aligned upper-end amount in a fat-friendly softgel. Missing branded sourcing and an all-trans guarantee leave some uncertainty about MK-7 quality.

The product offers focused support for calcium handling and vascular integrity rather than broad cardiovascular coverage. MK-7 can interfere with warfarin and related vitamin K antagonists, so users of these medicines need medically managed, consistent vitamin K intake.

Study evidence
Vitamin K Supportive 40 studies
Anti-Aging
Impact
Highest effect
B Goal FitA Strength of SupportC CoverageA+ Formula Quality
Vitamin K · 200 mcg

Vitamin K2 as MK-7 supports healthy calcium placement in arteries and bones, making it relevant to vascular and skeletal aging. Human evidence is promising for these age-related markers but does not establish broad healthspan extension by itself.

The 200 mcg amount is substantial and clearly disclosed. MK-7 and softgel delivery are favorable, though branded sourcing and all-trans purity are not stated. People taking warfarin or other vitamin K antagonist medicines should keep vitamin K intake consistent and follow their prescriber’s guidance.

Study evidence
Vitamin K Supportive 27 studies
General Health
Impact
Highest effect
B+ Goal FitA- Strength of SupportD+ CoverageA+ Formula Quality
Vitamin K · 200 mcg

Vitamin K2 in the MK-7 form supports calcium handling in bones and soft tissues, making it a relevant foundational nutrient. The substantial amount and softgel delivery provide focused depth for this pathway.

The label does not identify a branded source or guarantee the all-trans form, which limits confidence in raw-material quality. MK-7 can counteract warfarin and related vitamin K antagonists, so users of those medicines need clinician-guided consistency rather than unsupervised changes.

Study evidence
Vitamin K Supportive 34 studies

Ingredients

IngredientAmount per serving
Vitamin K-2 (Menaquinone-7)
200 mcg
Adults 18–50
Report overview
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The softgel provides a well-aligned upper-end MK-7 dose in an absorption-friendly format. No branded source or all-trans guarantee is disclosed, which limits confidence in source quality. The serving cost is unusually high, and MK-7 may interfere with warfarin and related vitamin K antagonists.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsHeart Health Cardiovascular Support forVitamin K
  2. Vitamin K Supplementation for the Prevention of Cardiovascular Disease: Where Is the Evidence? A Systematic Review of Controlled Trials.
    Vlasschaert C; Goss CJ; Pilkey NG; McKeown S; Holden RM · Nutrients · 2021
    Systematic review9 studies pooledHeart Health forVitamin K
  3. Vitamin K Supplementation to Improve Vascular Stiffness in CKD: The K4Kidneys Randomized Controlled Trial.
    Witham MD; Lees JS; White M; Band M; Bell S; Chantler DJ; Ford I; Fulton RL; Kennedy G; Littleford RC; McCrea IV; McGlynn D; Panarelli M; Ralston MR; Rutherford E; Severn A; Thomson N; Traynor JP; Struthers AD; Wetherall K; Mark PB · Journal of the American Society of Nephrology : JASN · 2021
    Randomized trial159 participantsHeart Health forVitamin K
  4. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  5. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials.
    Huang ZB; Wan SL; Lu YJ; Ning L; Liu C; Fan SW · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Meta-analysis6,759 participants19 studies pooledBone Health forVitamin K
  6. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  7. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  8. The relationship between vitamin K and peripheral arterial disease.
    Vissers LET; Dalmeijer GW; Boer JMA; Verschuren WMM; van der Schouw YT; Beulens JWJ · Atherosclerosis · 2017
    Cohort study36,629 participantsCardiovascular Support forVitamin K
  9. Interventions to Attenuate Cardiovascular Calcification Progression: A Systematic Review of Randomized Clinical Trials.
    Murali S; Smith ER; Tiong MK; Tan SJ; Toussaint ND · Journal of the American Heart Association · 2024
    Systematic review9,901 participants49 studies pooledCardiovascular Support forVitamin K
  10. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging General Health forVitamin K
  11. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  12. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  13. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  14. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  15. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  16. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  17. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  18. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  19. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  20. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  21. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support Heart Health forVitamin K
  22. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  23. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  24. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  25. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  26. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K