Mitochondrial NRG

Mitochondrial NRG

Designs for Health4.8 (86 ratings)
Format:Capsule Quantity: 120 Capsule(s) · 30 servings
Goals
$83.99 $2.79 per serving

Product analysis

48 out of 100

Mitochondrial NRG supports normal energy metabolism through its B vitamins and CoQ10. Several small or unclear amounts and a high serving cost limit its appeal as a targeted energy supplement.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality42

The riboflavin source is a favorable form choice, and thiamin uses a standard source. Many other named sources lack enough information for a confident quality comparison, while several preparations are unspecified.

Ingredient Transparency70

Listed amounts are disclosed, but several source forms and the turmeric mixture proportions are missing. These omissions prevent a close comparison of the full formula.

Value For Money26

The serving is costly for several of its identifiable contributions, including CoQ10, creatine and carnitine. Value remains uncertain for other ingredients rather than clearly favorable.

Customer Satisfaction74

Customer ratings indicate high satisfaction. The small feedback pool limits how broadly that pattern can be applied.

Product Focus32

Normal energy metabolism is a clearer purpose than the many wider claims. The extensive mixture and small amounts of several additions make it less focused for a specific outcome.

Format
Capsule
Container
120 Capsule(s)
Per serving
$2.79
Customer rating
4.8 · 86 ratings
Report analysis

Goals

Impact
Moderate effect
C- Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Vitamin B5 · 50 mgMagnesium · 100 mgRiboflavin · 10 mgThiamin · 50 mgVitamin B12 · 2000 mcgCoenzyme Q-10 · 100 mgCreatine · 550 mg
Study evidence
Creatine Supportive 49 studies
Magnesium Supportive 4 studies
Thiamin Disputed 12 studies
Impact
Moderate effect
C- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Niacin · 5 mgVitamin B12 · 2000 mcgRiboflavin · 10 mgThiamin · 50 mgVitamin B5 · 50 mgVitamin B6 · 5 mgMagnesium · 100 mgResveratrol · 100 mgCreatine · 550 mgCoenzyme Q-10 · 100 mg
Study evidence
Creatine Supportive 21 studies
Magnesium Supportive 61 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies
Heart Health
Impact
Moderate effect
D Ingredient FitF PathwaysA+ EvidenceA Formulation Logic
Magnesium · 100 mgCoenzyme Q-10 · 100 mgVitamin B12 · 2000 mcgVitamin B6 · 5 mg
Study evidence
Magnesium Supportive 158 studies
Niacin Supportive 105 studies
Vitamin B6 Supportive 44 studies
Longevity
Impact
Moderate effect
D Ingredient FitF PathwaysC- EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mgMagnesium · 100 mgVitamin B12 · 2000 mcgCreatine · 550 mg
Study evidence
Creatine Supportive 31 studies
Magnesium Supportive 12 studies
Cardiovascular Support
Impact
Moderate effect
D- Ingredient FitD- PathwaysD+ EvidenceA- Formulation Logic
Magnesium · 100 mgCoenzyme Q-10 · 100 mgL-Carnitine · 200 mgVitamin B12 · 2000 mcgVitamin B6 · 5 mgNiacin · 5 mg
Study evidence
Magnesium Supportive 123 studies
Niacin Supportive 136 studies
Vitamin B6 Supportive 35 studies
Inflammation
Impact
Lower effect
F Ingredient FitF PathwaysC EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg
Study evidence
Magnesium Supportive 41 studies
Skin Health
Impact
Moderate effect
D Ingredient FitD- PathwaysB EvidenceA+ Formulation Logic
Resveratrol · 100 mg
Study evidence
Niacin Supportive 61 studies

Ingredients

IngredientAmount per servingScore
Thiamine (Thiamine Hydrochloride)
50 mg 76
Riboflavin (Riboflavin 5-Phosphate)
10 mg 68
Vitamin B3 (Niacinamide)
5 mg
Vitamin B-6 (Pyridoxal 5-Phosphate)
5 mg
Vitamin B12 (Methylcobalamin)
2000 mcg 84
Magnesium (Creatine MagnaPower)
100 mg
Manganese (TRAACS Manganese Glycinate Chelate)
500 mcg
Creatine (Creatine MagnaPower Magnesium Creatine Chelate)
550 mg 48
L-Carnitine (L-Carnitine Fumarate)
200 mg 44
Fumaric Acid (L-Carnitine Fumarate)
150 mg
D-Ribose
100 mg
Malic Acid
100 mg
Succinic Acid
100 mg
Natural Coenzyme Q10 (Ubiquinone)
100 mg 52
Alpha Lipoic Acid
100 mg
Trans Resveratrol
100 mg 73
Curcumin C3 Complex(R) (Curcuminoids)
100 mg 66
Pantethine
50 mg 73
Gluten Free Adults 18–50
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
Each serving provides 2,000 mcg of B12 at a high cost per 1,000 mcg, based on the full product price. The B12 is Methylcobalamin, a bioactive form.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

The B12 is Methylcobalamin, a bioactive form.
Bioactive B12 Form Selection
The B12 is Methylcobalamin, a bioactive form.

Dose, Safety & Label Transparency100

Each serving provides 2,000 mcg of B12, an amount used for higher needs. The label names Methylcobalamin and gives its B12 amount.
Therapeutic Dosage Level
Each serving provides 2,000 mcg of B12, an amount used for higher needs.
Label and Form Transparency
The label names Methylcobalamin and gives its B12 amount.

Value20

The cost per 1,000 mcg of B12 is high, based on the full product price.
Price per 1,000 mcg B12
The cost per 1,000 mcg of B12 is high, based on the full product price.
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value
The serving provides 50 mg of thiamin, a high-potency amount, but its cost for that amount is high. It uses Thiamine Hydrochloride. The listed ingredients do not trigger the specified artificial color or sweetener concerns.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

Thiamine Hydrochloride is a standard water-soluble form. The listed ingredients do not trigger the specified artificial color or sweetener concerns.
Thiamin Chemical Form
Thiamine Hydrochloride is a standard water-soluble form.
Excipient Purity
The listed ingredients do not trigger the specified artificial color or sweetener concerns.

Dose, Safety & Label Transparency100

The serving provides 50 mg of thiamin, a high-potency amount.
Thiamin Dosage Potency
The serving provides 50 mg of thiamin, a high-potency amount.
Label Transparency & Proprietary Blends
The thiamin amount is stated as 50 mg per serving.

Value40

The cost is high relative to the declared thiamin amount.
Price per Declared Dose
The cost is high relative to the declared thiamin amount.
A+ Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyF Value
A serving provides 10 mg of riboflavin. The cost per serving is high. It uses riboflavin 5-phosphate, a coenzyme form. No artificial colors, flavors or synthetic sweeteners are listed.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

It uses riboflavin 5-phosphate, a coenzyme form.
Riboflavin Form Quality
It uses riboflavin 5-phosphate, a coenzyme form.

Dose, Safety & Label Transparency64

A serving provides 10 mg of riboflavin. No artificial colors, flavors or synthetic sweeteners are listed.
Dosage for Energy & Metabolism
A serving provides 10 mg of riboflavin.
R5P Elemental Yield Transparency
The label states the amount of riboflavin provided from the phosphate form.
Additive Purity
No artificial colors, flavors or synthetic sweeteners are listed.

Value10

The cost per serving is high.
Price per Serving Value
The cost per serving is high.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  2. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  3. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  4. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  5. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  6. L-Carnitine supplementation reduces oxidized LDL cholesterol in patients with diabetes.
    Malaguarnera M; Vacante M; Avitabile T; Malaguarnera M; Cammalleri L; Motta M · The American journal of clinical nutrition · 2009
    Randomized trial81 participantsCardiovascular Support Heart Health forL-Carnitine
  7. L-Carnitine's Effect on the Biomarkers of Metabolic Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Choi M; Park S; Lee M · Nutrients · 2021
    Meta-analysis9 studies pooledCardiovascular Support Heart Health forL-Carnitine
  8. The Effects of L-Carnitine Supplementation on Weight Loss, Glycemic Control, and Cardiovascular Risk Factors in Patients With Type 2 Diabetes: A Systematic Review and Dose-response Meta-Analysis of Randomized Controlled Trials.
    Mirrafiei A; Jayedi A; Shab-Bidar S · Clinical therapeutics · 2024
    Meta-analysis2,041 participants21 studies pooledCardiovascular Support forL-Carnitine
  9. The Effects of L-Carnitine on Echocardiographic Changes in Patients With β-Thalassemia Major and Intermedia.
    Shahidi M; Hashemi SR; Fattahi N; Roshani D; Vahedi S; Sharifi P; Moradveisi B · Journal of pediatric hematology/oncology · 2020
    Randomized trial60 participantsCardiovascular Support forL-Carnitine
  10. Efficacy and tolerability of combined treatment with L-carnitine and simvastatin in lowering lipoprotein(a) serum levels in patients with type 2 diabetes mellitus.
    Solfrizzi V; Capurso C; Colacicco AM; D'Introno A; Fontana C; Capurso SA; Torres F; Gadaleta AM; Koverech A; Capurso A; Panza F · Atherosclerosis · 2007
    Randomized trial52 participantsCardiovascular Support forL-Carnitine
  11. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  12. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  13. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  14. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  15. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  16. The current state of niacin in cardiovascular disease prevention: a systematic review and meta-regression.
    Lavigne PM; Karas RH · Journal of the American College of Cardiology · 2013
    Meta-analysis9,959 participants11 studies pooledCardiovascular Support forNiacin
  17. Effects of niacin on apo A1 and B levels: a systematic review and meta-analysis of randomised controlled trials.
    Saboori S; Yousefi Rad E; Tammam J; Thondre PS; Coe S · The British journal of nutrition · 2024
    Meta-analysis12 studies pooledCardiovascular Support forNiacin
  18. Effect of lipid-lowering therapies on lipoprotein(a) levels: a comprehensive meta-analysis of randomized controlled trials.
    Xie S; Galimberti F; Olmastroni E; Carugo S; Catapano AL; Casula M; META-LIPID Group · Atherosclerosis · 2025
    Meta-analysis145,314 participants147 studies pooledCardiovascular Support forNiacin
  19. Extended-release niacin vs gemfibrozil for the treatment of low levels of high-density lipoprotein cholesterol. Niaspan-Gemfibrozil Study Group.
    Guyton JR; Blazing MA; Hagar J; Kashyap ML; Knopp RH; McKenney JM; Nash DT; Nash SD · Archives of internal medicine · 2000
    Randomized trial173 participantsCardiovascular Support forNiacin
  20. Equivalent efficacy of a time-release form of niacin (Niaspan) given once-a-night versus plain niacin in the management of hyperlipidemia.
    Knopp RH; Alagona P; Davidson M; Goldberg AC; Kafonek SD; Kashyap M; Sprecher D; Superko HR; Jenkins S; Marcovina S · Metabolism: clinical and experimental · 1998
    Randomized trial223 participantsCardiovascular Support forNiacin