Coenzymate B Complex Orange Flavored

Coenzymate B Complex Orange Flavored

Source Naturals4.8 (1,102 ratings)
Format:Lozenge Quantity: 60 Liquid(s) · 30 servings
Goals
$20.19 $0.67 per serving

Product analysis

55 out of 100

Coenzymate B Complex Orange Flavored supplies B vitamins to help fill nutritional gaps that can affect energy use and normal nerve function. Missing proportions within its vitamin mixtures make the formula harder to compare precisely.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality44

Riboflavin and B5 have favorable forms, and the niacin forms are clearly named. Folate uses a less favorable form, while the quality of several other ingredients remains uncertain.

Ingredient Transparency71

All ingredient amounts are disclosed, but some forms are missing. The proportions within the niacin, B6 and B12 mixtures are also undisclosed, limiting precise comparisons.

Value For Money35

Value looks limited for several of the B vitamins, particularly niacin, folate and B5. Riboflavin offers more moderate value, while the value of several other ingredients remains uncertain.

Customer Satisfaction84

Customer ratings are very favorable. The review count provides a substantial base of customer feedback, without establishing health benefits.

Product Focus56

The formula has a broad nutrient focus rather than one narrow purpose. Its clearest role is replacing low intakes of B vitamins, which can affect normal metabolism, mood and concentration.

Format
Lozenge
Container
60 Liquid(s)
Per serving
$0.67
Customer rating
4.8 · 1,102 ratings
Report analysis

Goals

Impact
High effect
A- Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Vitamin B5 · 25 mgRiboflavin · 10 mgThiamin · 13 mgVitamin B12 · 860 mcgCoenzyme Q-10 · 12 mg
Study evidence
Thiamin Disputed 12 studies
Impact
High effect
B+ Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 150 mcgNiacin · 39 mgVitamin B12 · 860 mcgRiboflavin · 10 mgThiamin · 13 mgVitamin B5 · 25 mgVitamin B6 · 10 mgCoenzyme Q-10 · 12 mg
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per servingScore
Total Carbohydrates
1 Gram(s)
Vitamin C (Niacinamide Ascorbate)
17 mg
Thiamine
13 mg 45
Riboflavin (Flavin Mononucleotide)
10 mg 76
Niacin (Inositol Hexanicotinate, Niacinamide Ascorbate, Nicotinamide Adenine Dinucleotide)
39 mg 55
Vitamin B-6 (Coenzymated, Pyridoxal 5-Phosphate)
10 mg
Folate (Folic Acid)
400 mcg 10
Vitamin B12 (Hydroxocobalamin, Methylcobalamin)
860 mcg 70
Biotin
150 mcg
Pantothenic Acid (Calcium D-Pantothenate)
25 mg 61
Sodium
5 mg
Coenzyme Q10
12 mg 31
Inositol (Inositol Hexanicotinate)
7 mg
Adults 18–50
Report overview
A+ Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyF Value
Each serving provides 860 mcg of B12, with a high cost per 1,000 mcg. It uses methylcobalamin and hydroxocobalamin; hydroxocobalamin requires conversion in the body. The individual amounts of the two forms are unknown.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

It uses methylcobalamin and hydroxocobalamin; hydroxocobalamin requires conversion in the body.
Bioactive B12 Form Selection
It uses methylcobalamin and hydroxocobalamin; hydroxocobalamin requires conversion in the body.

Dose, Safety & Label Transparency64

The serving provides 860 mcg of B12. The individual form amounts are unknown.
Therapeutic Dosage Level
Each serving provides 860 mcg of B12. It falls below the amount considered meaningful for people with higher needs.
Label and Form Transparency
The total B12 amount is listed, but the amount of each form is unknown.

Value20

The cost per 1,000 mcg of B12 is high.
Price per 1,000 mcg B12
The cost per 1,000 mcg of B12 is high.
C- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyF Value
A serving provides 39 mg of niacin. The cost per serving is high for the niacin contribution. The sources are Inositol Hexanicotinate, Niacinamide Ascorbate and Nicotinamide Adenine Dinucleotide, in undisclosed proportions. The proportions limit what can be said about each source.
How this ingredient is rated

Active Ingredient Quality & Bioavailability60

The sources are Inositol Hexanicotinate, Niacinamide Ascorbate and Nicotinamide Adenine Dinucleotide, in undisclosed proportions.
Niacin Form & Goal Alignment
The sources are Inositol Hexanicotinate, Niacinamide Ascorbate and Nicotinamide Adenine Dinucleotide, in undisclosed proportions.
Precursor Source Quality
The sources are Inositol Hexanicotinate, Niacinamide Ascorbate and Nicotinamide Adenine Dinucleotide, in undisclosed proportions.

Dose, Safety & Label Transparency67

A serving provides 39 mg of niacin. The form is named, but no explicit no-flush claim is available.
Clarity of Chemical Form
The sources are Inositol Hexanicotinate, Niacinamide Ascorbate and Nicotinamide Adenine Dinucleotide, in undisclosed proportions.
Form-Specific Dosage Efficacy
A serving provides 39 mg of niacin.
Flush Risk & Safety Labeling
No explicit no-flush claim is available.

Value20

The cost per serving is high for the niacin contribution.
Price Per Effective Serving
The cost per serving is high for the niacin contribution.
A+ Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyD+ Value
Each serving provides 10 mg of riboflavin. That is a maintenance-level amount. The cost per serving is moderate. It uses Riboflavin 5-Phosphate, an active coenzyme form. The available Other Ingredients information lists no artificial colors, flavors or synthetic sweeteners.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

It uses Riboflavin 5-Phosphate, an active coenzyme form.
Riboflavin Form Quality
It uses Riboflavin 5-Phosphate, an active coenzyme form.

Dose, Safety & Label Transparency64

Each serving provides 10 mg of riboflavin. That is a maintenance-level amount. The available Other Ingredients information lists no artificial colors, flavors or synthetic sweeteners.
Dosage for Energy & Metabolism
Each serving provides 10 mg of riboflavin. That is a maintenance-level amount.
R5P Elemental Yield Transparency
The riboflavin amount from the phosphate form is stated.
Additive Purity
The available Other Ingredients information lists no artificial colors, flavors or synthetic sweeteners.

Value50

The cost per serving is moderate.
Price per Serving Value
The cost per serving is moderate.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  2. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  3. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  4. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  5. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  6. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  7. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  8. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  9. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  10. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  11. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  12. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  13. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  14. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  15. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  16. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  17. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  18. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  19. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  20. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12