Hema-Plex Tablets

Hema-Plex Tablets

Natures Plus4.9 (92,919 ratings)
Format:Tablet Quantity: 30 Tablet(s) · 30 servings
Goals

Product analysis

60 out of 100

Hema-Plex Tablets combines iron with several vitamins and minerals for broader nutritional coverage. The undisclosed components of its added blend make that part of the formula harder to judge.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality61

Natural-form vitamin E and methylfolate are useful distinctions among the named vitamin sources. Quality is less clear for the unidentified blend and several other contributions.

Ingredient Transparency77

The listed amounts and most forms are disclosed. The proprietary complex still does not identify its full components.

Value For Money50

Several vitamin and mineral contributions offer favorable value. Niacin, vitamin B5 and cysteine are less compelling at the same serving cost.

Customer Satisfaction97

Buyer ratings are very positive. The extensive number of ratings gives a broad picture of satisfaction.

Product Focus15

The formula spreads its attention across many nutrients and intended uses. Unknown blend components also prevent a complete account of the active composition.

Format
Tablet
Container
30 Tablet(s)
Per serving
$0.41
Customer rating
4.9 · 92,919 ratings
Report analysis

Goals

Impact
High effect
B- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Vitamin B5 · 25 mgRiboflavin · 25 mgThiamin · 25 mgVitamin B12 · 500 mcgIron · 85 mg

Iron, folate and several B vitamins can help reduce fatigue when their intake is deficient, while vitamin C can address deficiency-related tiredness. These roles do not establish an additional energy boost in adequately nourished adults. The high declared iron amount does not establish more benefit above nutritional adequacy. Botanical mass does not supply a confirmed caffeine amount or prove an acute alertness effect.

How this product is rated for Energy

Ingredient fit72

Iron contributes a relevant declared amount, with formula focus and serving quantity shaping the ingredient finding.
Goal fit
Relevant ingredients sit within a broader formula containing ingredients aimed at other goals.
Dose adequacy
The serving provides a partial match to the saved amount comparisons, which are not clinical benefit percentages.

Pathways0

No energy pathway receives coverage. A nutrient contribution for deficiency-related fatigue remains separate from a stimulant effect or extra energy in adequate adults.
Depth
No energy pathway receives coverage; the nutrient contribution remains distinct from an alertness or general fatigue-relief effect.
Breadth
No energy area reaches the saved coverage target, so broad energy effects are not established.

Evidence98

Iron leads the saved evidence finding. The supplied context limits expectations according to nutrient status, preparation and the population studied.
Evidence strength
Iron provides the leading evidence contribution; its nutritional-status, population and preparation limits still determine the benefit that can be described.
Studied preparation
The included ingredients match the saved preparation comparisons; this does not establish a tested whole-product fatigue regimen.

Formulation logic100

The included ingredients meet the saved minimum amount comparisons, with no missing partner or configured conflict. These findings do not establish a combined benefit or overall safety.
Partner coverage
No missing required partner limits the included ingredients; this does not establish added benefit from combining them.
Conflicts
No configured ingredient conflict was identified; this does not establish overall safety or cover every possible interaction.
Effective doses
The included ingredients meet the saved minimum amount comparison, which is not proof of a clinically effective personal fatigue dose.
Study evidence
Iron Supportive 74 studies
Thiamin Disputed 12 studies
Impact
High effect
C Ingredient FitD- PathwaysB EvidenceA+ Formulation Logic
Zinc · 5 mgIron · 85 mgVitamin C · 300 mg

Iron can matter when iron deficiency contributes to diffuse shedding, but its amount here remains unresolved. Vitamin C supports normal collagen formation and iron absorption, while copper supports pigmentation and connective-tissue biology. These functions and the formula’s B vitamins do not establish independent regrowth; zinc and selenium fall below the saved inclusion criteria.

How this product is rated for Hair Health

Ingredient fit64

Relevant ingredients and their declared amounts shape this finding. The recognized amounts provide partial coverage of the supplied comparison anchors; unresolved amounts contribute nothing to this finding.
Goal fit
Relevant nutritional ingredients are present alongside a broader formula.
Dose adequacy
The recognized amounts provide partial coverage of the supplied comparison anchors; unresolved amounts contribute nothing to this finding.

Pathways44

The strongest recorded coverage concerns follicle antioxidant protection, rather than a demonstrated clinical hair outcome.
Depth
The strongest recorded coverage concerns follicle antioxidant protection, rather than a demonstrated clinical hair outcome.
Breadth
One named pathway reaches the supplied coverage criterion; broader coverage is limited.

Evidence78

Vitamin B12 provides the strongest recognized evidence contribution, subject to its specific hair-benefit limitations.
Evidence strength
Vitamin B12 provides the strongest recognized evidence contribution, subject to its specific hair-benefit limitations.
Studied preparation
The recognized preparations match those accepted in the saved comparison; that alone does not prove hair regrowth.

Formulation logic96

The saved findings identify no missing required partners or configured conflicts. The supplied amount criterion was not met for Iron.
Partner coverage
No missing required partner reduced the recognized ingredients’ contributions.
Conflicts
No configured ingredient conflict was recorded; this is not a general safety assessment.
Effective doses
The supplied amount criterion was not met for Iron.
Study evidence
Copper Adverse 4 studies
Folate Mixed 15 studies
Iron Disputed 25 studies
Niacin Disputed 2 studies
Selenium Disputed 7 studies
Vitamin E No effect 3 studies
Zinc Supportive 22 studies
Impact
Moderate effect
D Ingredient FitF PathwaysB- EvidenceA Formulation Logic
Iron · 85 mgVitamin B12 · 500 mcgVitamin B12 · 500 mcgVitamin B6 · 25 mgZinc · 5 mg

B6, B12 and folate provide the clearest relevant support through normal nutrient functions; correcting a shortfall may help fatigue or concentration. The iron amount is unresolved, and the small zinc amount adds little in the saved findings. Green tea's presence does not supply a quantified caffeine contribution.

How this product is rated for Productivity Boost

Ingredient fit50

The formula has a broad purpose, with only part of its ingredient mix directly relevant to this goal. The relevant amounts provide partial support, with smaller or unresolved amounts limiting the assessment.
Goal fit
The formula has a broad purpose, with only part of its ingredient mix directly relevant to this goal.
Dose adequacy
The relevant amounts provide partial support, with smaller or unresolved amounts limiting the assessment.

Pathways0

The saved findings identify nutritional support without a distinct alertness, memory or stress-fatigue route. The findings do not show broad support across several distinct aspects of productivity.
Depth
The saved findings identify nutritional support without a distinct alertness, memory or stress-fatigue route.
Breadth
The findings do not show broad support across several distinct aspects of productivity.

Evidence70

Vitamin B12 provides the strongest evidence contribution in the saved findings, with the scope and limitations of its supplied evidence retained. The saved findings recognize the relevant preparations at the assessed amounts.
Evidence strength
Vitamin B12 provides the strongest evidence contribution in the saved findings, with the scope and limitations of its supplied evidence retained.
Studied preparation
The saved findings recognize the relevant preparations at the assessed amounts.

Formulation logic94

No listed formulation conflict was matched in the saved findings. Some amounts limit the finding; Iron falls short or has an unresolved amount.
Partner coverage
The relevant ingredients can contribute without a missing required partner.
Conflicts
No listed formulation conflict was matched in the saved findings.
Effective doses
Some amounts limit the finding; Iron falls short or has an unresolved amount.
Study evidence
Iron Supportive 69 studies
Zinc Supportive 11 studies
Impact
High effect
C+ Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Niacin · 50 mgVitamin B12 · 500 mcgRiboflavin · 25 mgThiamin · 25 mgVitamin B5 · 25 mgVitamin B6 · 25 mgZinc · 5 mg

B vitamins help the body use carbohydrate, fat and protein through their normal cofactor roles. Those functions do not establish that extra vitamins raise energy expenditure when intake is adequate. Iron can matter when iron-deficiency anaemia lowers thyroid hormone and heat production, but its usable amount here is unknown. Green-tea presence and amount remain unresolved because the source declaration lacks matching imported facts, so no catechin or caffeine contribution can be inferred.

How this product is rated for Metabolism Support

Ingredient fit70

The ingredients receive recognition for their connection and amounts in the saved findings. Normal nutrient functions and comparison amounts do not establish a metabolic-rate increase.
Goal fit
Recognised ingredients share this formula with other actives, giving it a broader focus than metabolic rate alone.
Dose adequacy
Iron has no usable amount for comparison, while the other counted ingredients have substantial reference amounts.

Pathways0

No evaluated route to increased calorie expenditure receives recorded ingredient coverage.
Depth
No evaluated route to increased calorie expenditure receives recorded ingredient coverage.
Breadth
None of the evaluated routes has substantial recorded coverage, so broad support for increased energy expenditure is absent.

Evidence100

Vitamin B1 (Thiamin) leads the recorded evidence finding, but its normal metabolic role or other study outcomes do not establish thermogenesis.
Evidence strength
Vitamin B1 (Thiamin) leads the recorded evidence finding, but its normal metabolic role or other study outcomes do not establish thermogenesis.
Studied preparation
The counted ingredients receive preparation recognition in the saved finding, without establishing a direct energy-expenditure effect.

Formulation logic96

The counted ingredients have no missing required partners or identified conflicts among those evaluated. An unresolved amount limits that finding.
Partner coverage
No required ingredient partner is missing for the counted ingredients.
Conflicts
None of the evaluated conflicts was identified; the finding does not cover every possible interaction.
Effective doses
Iron has an unresolved usable amount and does not meet the minimum amount comparison.
Study evidence
Niacin Supportive 17 studies
Selenium Mixed 28 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies
Zinc Supportive 12 studies

Ingredients

IngredientAmount per servingScore
Vitamin C (Proprietary Esterified Complex)
300 mg
Vitamin E (D-Alpha-Tocopheryl Acetate)
30 IU 65
Thiamine (Thiamine Hydrochloride)
25 mg 65
Riboflavin
25 mg 63
Niacin (Niacinamide)
50 mg 65
Vitamin B6 (Pyridoxine Hydrochloride)
25 mg 80
Folate (Calcium L-5-Methyltetrahydrofolate)
400 mcg 92
Vitamin B12 (Methylcobalamin)
500 mcg 76
Pantothenic Acid (Calcium Pantothenate)
25 mg 61
Calcium Complex (Calcium Amino Acid Chelate)
25 mg
Iron Complex (Iron Amino Acid Chelate)
85 mg 45
Zinc (Zinc Monomethionine)
5 mg
Selenium (Selenium Amino Acid Chelate)
10 mcg
Copper (Copper Amino Acid Chelate)
2 mg 67
Manganese Complex (Manganese Amino Acid Chelate)
5 mg 84
L-Cysteine
50 mg 39
Proanthoplex (Proprietary Proanthocyanidin/Bioflavonoid Complex)
25 mg
Beet
15 mg
Bioperine (1-Piperoylpiperidine)
2.5 mg
Gluten Free Adults 18–50 Dairy Free Vegetarian
Report overview
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value
Each serving lists 5 mg of manganese as manganese amino acid chelate. The saved facts identify an amino acid chelate but do not specify which one.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The source is an amino acid chelate; the particular chelate is not specified in the saved facts.
Manganese Chemical Form
Manganese amino acid chelate is the identified source. The saved facts identify an amino acid chelate but do not specify which one.

Dose, Safety & Label Transparency100

Each serving lists 5 mg of manganese and identifies its source.
Manganese Dosage Efficacy & Safety
Each serving provides 5 mg of manganese.
Elemental Weight Disclosure
The saved facts identify 5 mg as manganese and specify its source.

Value80

A whole-product serving costs about $0.42.
Price per Serving vs. Median
A whole-product serving costs about $0.42.
A Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value
A serving lists 400 mcg of folate at a moderate cost per serving. It uses L-5-methyltetrahydrofolate calcium. The L form bypasses the MTHFR conversion step.
How this ingredient is rated

Active Ingredient Quality & Bioavailability91

The folate uses L-5-methyltetrahydrofolate calcium. It is an active form that bypasses the MTHFR conversion step.
Folate Form Hierarchy
It is an active form that bypasses the MTHFR conversion step.
Patented Sources & Isomeric Purity
The L designation indicates the active isomer; no named branded source is identified.

Dose, Safety & Label Transparency100

The serving declares 400 mcg of folate.
Folate Dosage by Declared Basis
The serving declares 400 mcg of folate.

Value80

The cost per serving is moderate.
Price per Bioavailable Serving
The cost per serving is moderate.
C- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD+ Value
A serving supplies 2 mg of copper as copper amino acid chelate. A serving also supplies 5 mg of zinc.
How this ingredient is rated

Active Ingredient Quality & Bioavailability58

The saved facts name copper amino acid chelate without establishing a more specific chemical identity. The saved facts give the elemental copper amount and name a source on the copper row.
Copper Form Bioavailability
The saved facts name copper amino acid chelate without establishing a more specific chemical identity.
Elemental Copper Labeling Clarity
The saved facts give the elemental copper amount and name a source on the copper row.

Dose, Safety & Label Transparency85

A serving supplies 2 mg of copper. A serving also supplies 5 mg zinc; its ratio to copper falls below the balance favored in the evaluation.
Copper Dosage Safety & Efficacy
A serving supplies 2 mg of copper.
Zinc-to-Copper Balance
A serving also supplies 5 mg zinc; its ratio to copper falls below the balance favored in the evaluation.

Value50

A whole-product serving costs about $0.42 and provides the stated copper amount.
Price Per Serving Efficiency
A whole-product serving costs about $0.42 and provides the stated copper amount.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Large-dose intravenous ferric carboxymaltose injection for iron deficiency anemia in heavy uterine bleeding: a randomized, controlled trial.
    Van Wyck DB; Mangione A; Morrison J; Hadley PE; Jehle JA; Goodnough LT · Transfusion · 2010
    Randomized trial477 participantsEnergy forIron
  2. The Effect of Parenteral or Oral Iron Supplementation on Fatigue, Sleep, Quality of Life and Restless Legs Syndrome in Iron-Deficient Blood Donors: A Secondary Analysis of the IronWoMan RCT.
    Macher S; Herster C; Holter M; Moritz M; Matzhold EM; Stojakovic T; Pieber TR; Schlenke P; Drexler C; Amrein K · Nutrients · 2021
    Randomized trial176 participantsEnergy forIron
  3. Ferric carboxymaltose vs. oral iron in the treatment of pregnant women with iron deficiency anemia: an international, open-label, randomized controlled trial (FER-ASAP).
    Breymann C; Milman N; Mezzacasa A; Bernard R; Dudenhausen J; FER-ASAP investigators · Journal of perinatal medicine · 2018
    Randomized trial252 participantsEnergy forIron
  4. Effect of iron therapy on fatigue symptoms in non-anaemic iron deficient women of reproductive age- A Randomized Controlled Trial.
    Sultana N; Bajwa FA; Sikandar MZ; Haider MM; Majeed T · JPMA. The Journal of the Pakistan Medical Association · 2026
    Randomized trial164 participantsEnergy forIron
  5. Intravenous iron isomaltoside treatment of women suffering from severe fatigue after postpartum hemorrhage.
    Holm C; Thomsen LL; Langhoff-Roos J · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019
    Randomized trial85 participantsEnergy forIron
  6. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  7. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  8. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  9. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  10. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  11. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  12. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  13. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  14. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  15. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  16. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  17. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  18. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  19. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  20. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12