Max B-ND
Premier Research Labs
Max B-ND
4.7
★ ★ ★ ★ ★
(191 ratings)
Vitamin B12 263 mcg
Biotin 334 mcg
Niacin 30 mg
Folate 1665 mcg
Score 95.0
Max B-ND is a premium liquid B-complex featuring highly bioavailable forms of B12 (three types), Folate (L-Methylfolate), B6 (P-5-P), and Riboflavin (R-5-P) for superior absorption and efficacy, supporting comprehensive health goals.
Quantity: 2 Fluid Ounce(s)Servings size: 3 mL (21 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
Cognitive Support
Metabolism Boost
leaderboard Score 95.0
Max B-ND is a premium liquid B-complex featuring highly bioavailable forms of B12 (three types), Folate (L-Methylfolate), B6 (P-5-P), and Riboflavin (R-5-P) for superior absorption and efficacy, supporting comprehensive health goals.
insights Analysis
Max B-ND by Premier Research Labs stands out as a high-quality B-complex supplement due to its advanced formulation. It uniquely provides Vitamin B12 in three bioavailable forms (Methylcobalamin, Hydroxycobalamin, and Adenosylcobalamin), and Folate as 5-Formyltetrahydrofolate Calcium, which is the active form of folate (L-Methylfolate). Furthermore, it includes Vitamin B6 as Pyridoxal 5'-Phosphate (P-5-P) and Riboflavin as Riboflavin 5'-Phosphate (R-5-P), both active forms ready for immediate use by the body. This meticulous selection of ingredients ensures superior absorption and utilization, particularly beneficial for individuals with genetic variations affecting B vitamin metabolism. The liquid delivery system further enhances absorption speed and ease of consumption. While its price point is significantly higher than many conventional B-complex supplements, this premium is justified by the exceptional quality and bioavailability of its components, making it an excellent choice for targeted nutritional support.
- Utilizes highly bioavailable/active forms of key B vitamins (Methylcobalamin, Hydroxycobalamin, Adenosylcobalamin for B12; 5-Formyltetrahydrofolate for Folate; P-5-P for B6; R-5-P for Riboflavin), maximizing absorption and utilization.
- Liquid delivery system offers potentially faster and better absorption, especially beneficial for individuals with digestive issues or difficulty swallowing pills.
- Provides a comprehensive spectrum of B vitamins in a single formula, addressing a wide range of B-vitamin related health goals.
- Higher price per serving compared to many traditional B-complex supplements on the market.
- Relatively lower number of online reviews compared to some widely established, more affordable B-complex brands, which might indicate less widespread brand recognition.
- The inclusion of both 'Niacin' and 'Niacinamide' might still lead to a mild 'niacin flush' for some highly sensitive individuals if the 'Niacin' component refers to nicotinic acid.
- Individuals sensitive to niacin may experience a temporary flushing sensation, redness, or itching, although the inclusion of Niacinamide is intended to minimize this effect. It is advisable to start with a smaller dose to assess tolerance.
$38.34($1.82 per serving)
 Pure Formulas | $ 38.34 |
bolt Effectiveness for goals
Folate is essential for cell growth and DNA formation. For women of childbearing age, adequate folate intake is crucial before and during early pregnancy to help prevent neural tube defects in the developing fetus. Public health recommendations often advise supplementation.
Vitamin B12 is crucial for red blood cell formation, neurological function, and DNA synthesis. Supplementation is often recommended for individuals with a deficiency, which can lead to fatigue and nerve issues. It also plays a role in energy metabolism.
Yes, Vitamin B12 is essential for the formation of myelin, the protective sheath around nerves. A prolonged deficiency can lead to nerve damage, manifesting as symptoms like tingling, numbness, balance problems, and even cognitive difficulties. Early diagnosis and treatment are important.
Prescription-strength Niacin (nicotinic acid) has been shown to improve cholesterol levels by lowering LDL ('bad') cholesterol and triglycerides, and raising HDL ('good') cholesterol. However, over-the-counter Niacin supplements typically contain lower doses or different forms that may not have the same effects. Always consult a healthcare provider for managing cholesterol.
Biotin is often marketed for hair, skin, and nail health, and it plays a role in the metabolism of fatty acids, which are important for these tissues. While some individuals with a true biotin deficiency may see improvements, evidence supporting its effectiveness for healthy individuals without a deficiency is limited. Research on its benefits for general hair and nail strength is ongoing.
schedule Dosage, timing & forms
Common dosages for Biotin supplements specifically for supporting hair and nail health often range from 1,000 micrograms (µg) to 10,000 µg daily. While generally considered safe, very high doses may interfere with certain lab tests. It is advisable to consult a healthcare professional for personalized recommendations.
Yes, these B vitamins are often found together in B-complex supplements, indicating they can typically be taken concurrently. They play synergistic roles in various bodily functions. However, individual sensitivities to specific B vitamins, especially Niacin, should be considered.
Nicotinic acid (Niacin) can cause a temporary skin flush, tingling, and warmth, known as the "niacin flush," especially at higher doses. Niacinamide (nicotinamide) and inositol hexanicotinate (no-flush niacin) are other forms that generally do not cause this flushing effect. These alternative forms have different physiological actions compared to nicotinic acid.
Folate is the general term for various forms of Vitamin B9, found naturally in foods. Folic acid is the synthetic form of Vitamin B9, commonly used in fortified foods and most supplements. L-Methylfolate is the active, metabolized form of folate that the body can directly use.
Vitamin B12 supplement dosages vary widely depending on individual needs and deficiency levels. Common daily dosages can range from 2.4 micrograms for general health maintenance up to 1000-2000 micrograms for addressing deficiencies. It is advisable to consult with a healthcare professional to determine the appropriate dosage for your specific situation.
health_and_safety Safety & interactions
A common side effect of Niacin, especially at higher doses, is a temporary flushing sensation, redness, itching, or tingling of the skin. This can often be minimized by taking Niacin with food, starting with a low dose, or choosing a 'no-flush' form. While 'no-flush' forms may reduce flushing, their effectiveness for cholesterol management may differ.
Yes, very high doses of Biotin can interfere with certain laboratory tests, particularly those that use biotin-streptavidin technology. These tests include some for thyroid function, cardiac troponins, and hormone levels, potentially leading to inaccurate results. It is advisable to inform your doctor and stop biotin supplementation for a few days before laboratory tests.
Yes, Vitamin B12, Niacin, Folate, and Biotin, along with other B vitamins, often work synergistically in the body and are generally safe when taken together within recommended dosages, such as in a multivitamin or B-complex. They play interconnected roles in metabolism and energy production. Always adhere to recommended dosages and consult a healthcare professional with any concerns.
High doses of Folate can potentially mask the symptoms of a Vitamin B12 deficiency. This is because Folate can alleviate the megaloblastic anemia associated with B12 deficiency, but it does not address the underlying neurological damage. It's important to ensure adequate B12 intake when supplementing with Folate.
Niacin can interact with statins, potentially increasing muscle-related side effects, and can affect blood pressure medications. Metformin and proton pump inhibitors can interfere with Vitamin B12 absorption over time. Folate can interact with drugs like methotrexate and some anti-epileptic medications, so it's crucial to discuss all supplements with a healthcare provider if you are on prescription medications.
Ingredients
| Ingredient | Amount per serving |
|---|---|
| Thiamine (Vitamin B1, Thiamine Hydrochloride) | 1 mg |
| Riboflavin (R-5-P) | 1.6 mg |
| Niacin (Vitamin B3, Niacinamide) | 30 mg |
| Vitamin B6 (Pyridoxine Hydrochloride, P-5-P) | 3 mg |
| Folate (5-Formyltetrahydrofolate Calcium) | 1665 mcg |
| Vitamin B12 (Methylcobalamin, Hydroxycobalamin, Adenosylcobalamin) | 263 mcg |
| Biotin | 334 mcg |
| Pantothenic Acid (Vitamin B5, Calcium D-Pantothenate) | 3.3 mg |
Categories
Vitamin B12 98.0
The inclusion of three distinct, active forms of B12 (Methylcobalamin, Hydroxycobalamin, Adenosylcobalamin) provides unparalleled bioavailability and comprehensive support for nervous system health and energy production, accommodating diverse metabolic needs.
Folate 98.0
Utilizing 5-Formyltetrahydrofolate Calcium, an active and body-ready form of folate, is a significant advantage. This bypasses the need for the body to convert synthetic folic acid, ensuring superior effectiveness for DNA synthesis, cell division, and homocysteine regulation.
Niacin 85.0
With a substantial dosage combining both Niacin and Niacinamide, the product supports energy metabolism and cellular signaling. While Niacinamide is non-flushing, the general 'Niacin' component might still induce a flush in sensitive individuals, though it contributes to broad metabolic support.
Goals
Energy 95.0
The diverse active forms of B vitamins, particularly those involved in the Krebs cycle like Riboflavin and Thiamine, ensure highly efficient conversion of food into usable cellular energy. This superior bioavailability directly translates to enhanced vitality and fatigue reduction.
Brain Health 95.0
By supplying essential B vitamins (Folate, B6, B12) in their active forms, the product directly supports the synthesis of crucial neurotransmitters and the maintenance of nerve cell integrity. This contributes to sharp focus, memory retention, and overall optimal brain function.
Cognitive Support 95.0
The bioavailable forms of B6, B12, and Folate are critical for optimal brain function, including cognitive processes like memory, learning, and concentration. Their direct usability ensures efficient support for neurological pathways.
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