The Big One without Iron
Metabolic Maintenance
The Big One without Iron
4.7
★ ★ ★ ★ ★
(511 ratings)
Vitamin B6 25 mg
Vanadium 50 mcg
Manganese 5 mg
Thiamin 25 mg
Vitamin B5 100 mg
Vitamin K 100 mcg
Riboflavin 25 mg
Score 92.0
A premium, comprehensive multivitamin featuring highly bioavailable forms of B vitamins and chelated minerals, designed for optimal absorption and broad-spectrum health support without iron.
Quantity: 90 Capsule(s)Servings size: 1 Capsule(s) (90 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
General Health
Heart Health
leaderboard Score 92.0
A premium, comprehensive multivitamin featuring highly bioavailable forms of B vitamins and chelated minerals, designed for optimal absorption and broad-spectrum health support without iron.
insights Analysis
This product is a well-formulated, high-potency multivitamin that offers a wide array of essential vitamins and minerals. A significant strength lies in its use of activated B vitamins (Methylcobalamin for B12, Riboflavin 5-Phosphate for B2, Pyridoxal 5-Phosphate for B6) and chelated mineral forms (Zinc Citrate, Manganese Glycinate, Molybdenum Glycinate, Boron Citrate, L-Selenomethionine), which are generally superior for absorption and direct utilization by the body. The inclusion of both Vitamin K1 and K2 (a crucial form for bone and cardiovascular health) and mixed tocopherols for Vitamin E further enhances its quality. Many online reviews and nutritionist perspectives highlight the importance of these bioavailable forms for efficacy, often noting improvements in energy levels and overall well-being. The product's exclusion of iron makes it particularly suitable for individuals who do not require additional iron supplementation, such as adult men or post-menopausal women, avoiding potential iron overload. While the quantity of reviews is moderate, the sentiment is overwhelmingly positive, reflecting user satisfaction with its perceived benefits. Its price point reflects the quality and complexity of its ingredient profile.
- Contains highly bioavailable and active forms of B vitamins (Methylcobalamin B12, Pyridoxal 5-Phosphate B6, Riboflavin 5-Phosphate B2), which are better absorbed and utilized by the body.
- Includes a broad spectrum of chelated minerals (Zinc Citrate, Manganese Glycinate, Molybdenum Glycinate, Boron Citrate, Copper Gluconate, Selenium as L-Selenomethionine), enhancing mineral absorption.
- Features both Vitamin K1 and K2, important for bone and cardiovascular health beyond just Vitamin D.
- Formulated without iron, catering to individuals who do not require or should avoid supplemental iron.
- Utilizes multiple forms of Vitamin A (Palmitate and Mixed Carotenoids) and Vitamin E (Mixed Tocopherols), providing a more complete antioxidant profile.
- The dosage of certain individual nutrients, while generally robust for a multivitamin, might be insufficient for therapeutic intervention in cases of significant deficiency or specific health conditions.
- Given its comprehensive and high-quality formulation, the product's cost per serving is higher than basic multivitamin options, which might be a barrier for some budget-conscious consumers.
- Individuals on blood-thinning medication should consult a healthcare professional due to the inclusion of Vitamin K, as it can interfere with anticoagulant therapy.
- Consumers should be aware of the relatively high dosages of some vitamins (e.g., B vitamins, Vitamin A) and ensure they do not exceed tolerable upper intake levels from other dietary sources or supplements.
$48.00($0.53 per serving)
 iHerb | $ 48.00 | |
 Amazon | $ 48.00 | |
 Pure Formulas | $ 48.00 |
bolt Effectiveness for goals
B vitamins act as coenzymes in numerous metabolic pathways, essential for converting food into energy. When taken together, they support energy production, cellular metabolism, and nervous system health. Their combined presence ensures comprehensive support for these vital bodily processes.
Active or coenzyme forms, such as methylcobalamin (B12) and pyridoxal 5-phosphate (B6), are readily usable by the body without requiring conversion. This can enhance their bioavailability and effectiveness, particularly for individuals with genetic variations that affect nutrient metabolism. These forms directly support processes like homocysteine metabolism and neurotransmitter synthesis.
Vitamin D3 aids in calcium absorption, while Vitamin K2 helps direct that calcium to the bones and teeth, preventing its accumulation in soft tissues like arteries. This synergistic relationship is crucial for maintaining bone mineral density and supporting arterial flexibility. Together, they contribute to the proper utilization of calcium in the body.
Zinc and copper compete for absorption in the small intestine. An imbalance, particularly excessive zinc, can lead to copper deficiency over time. A balanced ratio helps ensure adequate levels of both essential trace minerals, which are crucial for immune function, enzyme activity, and antioxidant defense.
Vitamin E is a group of compounds, and mixed tocopherols provide a broader spectrum (alpha, beta, gamma, delta) of these antioxidants. D-alpha-tocopheryl acid succinate is a stable and bioavailable form of alpha-tocopherol. Providing multiple forms offers more comprehensive antioxidant protection and supports various physiological functions.
schedule Dosage, timing & forms
Activated forms are often used because they are already in a coenzyme state, meaning the body may not need to convert them to utilize them effectively. This can be beneficial for individuals with genetic variations that affect conversion pathways.
Yes, fat-soluble vitamins like A, D, E, and K are best absorbed when consumed with a meal that contains some dietary fat. This helps facilitate their uptake into the bloodstream.
Chelated minerals are bound to amino acids, which can improve their bioavailability and absorption in the digestive tract. This binding helps protect the mineral from interacting with other compounds that might inhibit its absorption.
Vitamin K1 primarily supports blood clotting, while Vitamin K2 is more involved in bone and cardiovascular health. Including both forms aims to provide comprehensive support for different physiological processes.
High doses of biotin, often found in supplements, have been shown to interfere with certain lab tests, particularly those relying on biotin-streptavidin technology. It's advisable to inform healthcare providers about biotin supplementation before blood tests.
health_and_safety Safety & interactions
Vitamin K, including both K1 and K2 forms, plays an essential role in blood clotting. Individuals taking anticoagulant medications like warfarin should consult their healthcare provider before using any supplement containing Vitamin K, as it may interfere with the medication's effectiveness. This interaction is important for maintaining the correct therapeutic effect of blood thinners.
This supplement contains a significant amount of Vitamin A, including both preformed Vitamin A (palmitate) and carotenoids. High doses of preformed Vitamin A can be a concern for liver health and may be teratogenic if taken during pregnancy. Individuals who are pregnant, may become pregnant, or have pre-existing liver conditions should consult a healthcare professional.
This supplement provides a substantial amount of Vitamin B6, combining two forms: Pyridoxine Hydrochloride and Pyridoxal 5-Phosphate. While generally safe, very high daily intake over extended periods, typically from single-nutrient supplements, has been associated with peripheral neuropathy in some individuals. It is advisable to discuss any concerns about B6 intake with a healthcare provider.
This supplement contains both zinc and copper, which are essential minerals. These two minerals compete for absorption in the body, and a long-term imbalance, particularly excessively high zinc intake, can potentially lead to a copper deficiency. The amounts in a balanced multivitamin are generally formulated to prevent this, but individual needs and other dietary sources should be considered.
Iodine is crucial for the production of thyroid hormones, but its supplementation can interact with existing thyroid conditions like hyperthyroidism or autoimmune thyroid disease, and with thyroid medications. Individuals with any pre-existing thyroid concerns should consult their physician before using any iodine-containing supplement. Monitoring by a healthcare provider is recommended.
Ingredients
| Ingredient | Amount per serving |
|---|---|
| Vitamin A (Vitamin A Palmitate, Natural Mixed Carotenoids) | 2400 mcg RAE |
| Vitamin C (Ascorbyl Palmitate, Ascorbic Acid) | 125 mg |
| Vitamin D3 (Cholecalciferol) | 25 mcg |
| Vitamin E (Mixed Tocopherols, D-Alpha-Tocopheryl Acid Succinate) | 67 mg |
| Vitamin K (Vitamin K2, Vitamin K1) | 100 mcg |
| Thiamine (Thiamine Mononitrate) | 25 mg |
| Riboflavin (Riboflavin 5-Phosphate) | 25 mg |
| Niacin (Niacinamide) | 100 mg NE |
| Vitamin B6 (Pyridoxine Hydrochloride, Pyridoxal 5-Phosphate) | 25 mg |
| Folate | 667 mcg DFE |
| Vitamin B12 (Methylcobalamin) | 100 mcg |
| Biotin | 200 mcg |
| Pantothenic Acid (Calcium D-Pantothenate) | 100 mg |
| Iodine (Potassium Iodide) | 100 mcg |
| Zinc (Zinc Citrate) | 15 mg |
| Selenium (L-Selenomethionine) | 100 mcg |
| Copper (Copper Gluconate) | 1 mg |
| Manganese (Manganese Glycinate) | 5 mg |
| Chromium (Chromium Polynicotinate) | 100 mcg |
| Molybdenum (Molybdenum Glycinate) | 50 mcg |
| Betaine HCl | 25 mg |
| Boron (Boron Citrate) | 1 mg |
| Vanadium (Vanadyl Sulfate) | 50 mcg |
Categories
Vitamin B12 95.0
The product uses Methylcobalamin, which is the active and most bioavailable form of Vitamin B12, ensuring optimal absorption and utilization for energy production and neurological health.
Vitamin B6 90.0
The product includes both Pyridoxine Hydrochloride and Pyridoxal 5-Phosphate (P5P), the active coenzyme form of Vitamin B6. This combination ensures broad and efficient support for protein metabolism, neurotransmitter synthesis, and hormone regulation.
Riboflavin 90.0
The inclusion of Riboflavin 5-Phosphate, the active coenzyme form of Vitamin B2, ensures superior bioavailability compared to standard riboflavin. This supports critical roles in energy production and antioxidant defense.
Goals
General Health 95.0
As a comprehensive multivitamin with high-quality, bioavailable forms of vitamins and chelated minerals, this product serves as an excellent daily foundation for overall health and well-being. It helps fill dietary gaps and ensures adequate intake of crucial micronutrients for various bodily functions.
Energy 90.0
The product provides a comprehensive blend of B vitamins, including active forms like Methylcobalamin and Riboflavin 5-Phosphate, which are crucial cofactors in cellular energy production. These forms are readily utilized by the body, supporting sustained energy levels effectively.
Metabolism Boost 90.0
The complete spectrum of B vitamins, vital for converting food into energy, combined with essential trace minerals like Chromium, Manganese, and Molybdenum, comprehensively supports metabolic processes. The active forms of B vitamins ensure efficient metabolic enzymatic reactions.