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One-Per-Day Tablets

Life Extension
4.8
(16747 ratings)
Iodine 150 mcg
Selenium 200 mcg
Chromium 200 mcg
Thiamin 75 mg
Riboflavin 50 mg
Molybdenum 100 mcg
Boron 3 mg
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Score98

A high-potency, comprehensive multivitamin packed with essential nutrients, activated B vitamins, and beneficial complementary compounds in a convenient single-tablet serving.

How scoring works
Quantity:60 Tablet(s)(60 servings)
Goals:
General Health
Skin Health
Brain Health
Energy
Anti-Inflammatory Support
Vision Support
Detoxification
Immunity

Score 98

A high-potency, comprehensive multivitamin packed with essential nutrients, activated B vitamins, and beneficial complementary compounds in a convenient single-tablet serving.

How scoring works
$18.38($0.30 per serving)
iHerb
$ 18.38
Walmart
$ 18.38
Vitacost
$ 20.23
Pure Formulas
$ 18.38
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Analysis

Life Extension's One-Per-Day Tablets provide a broad spectrum of essential vitamins and minerals, many in notably high doses. It includes key B vitamins in activated forms like methylfolate and methylcobalamin, alongside a substantial amount of Vitamin D3 and a generous mix of Vitamin C forms, aiming to support various body functions.

Beyond the basics, this formula stands out with additions like Alpha Lipoic Acid, Bio-Quercetin, Lycopene, Marigold extract for vision support, and Apigenin. These extra compounds can contribute to cellular health and overall wellness, making it more than just a standard multivitamin.

While many ingredients are in well-absorbed forms, such as L-OptiZinc and chelated minerals like boron and molybdenum, the magnesium is supplied as magnesium oxide. This form may not be as readily absorbed by some individuals, which is a minor point to consider in an otherwise strong nutrient profile.

Pros

  • Offers a very comprehensive blend of essential vitamins and minerals.
  • Includes activated forms of B vitamins (e.g., methylfolate, methylcobalamin, P5P) for better utilization.
  • Contains additional beneficial compounds like Alpha Lipoic Acid, Quercetin, Lycopene, and Marigold extract.
  • High doses of many nutrients, suitable for those seeking more robust daily support.
  • Convenient single-tablet serving for daily intake.

Cons

  • Some vitamin and mineral doses are very high, potentially exceeding daily needs for certain individuals.
  • Magnesium is supplied as magnesium oxide, which may not be optimally absorbed by everyone.
  • The extensive ingredient list and high dosages might not be necessary for individuals with already nutrient-rich diets.

Warnings

  • Individuals sensitive to high doses of B vitamins may experience increased energy or mild digestive upset.
  • The high selenium content (600mcg) is well above the standard daily allowance; consult with a professional if you have concerns about long-term high intake.
  • Always discuss new supplements with a healthcare professional, especially if taking other medications or supplements.

Nutrient quality

97 Highest impact

Elite nutrient forms like Se-Methyl L-Selenocysteine and OptiZinc offer superior biological utility. Potency levels are robust across nearly all vitamins and minerals to address diverse nutritional gaps.

Ingredient transparency

99 Highest impact

Labeling identifies each nutrient form and its respective dosage with high precision. Clear identification of phytosome complexes and mineral chelates ensures high transparency for the end user.

Customer satisfaction

97 Highest impact

Strong average ratings and a statistically massive volume of positive feedback reflect high consumer trust. User reports consistently support the formula's effectiveness for maintaining daily vitality and metabolic health.

Value for money

99 Highest impact

Elite ingredient quality and high nutrient density offer exceptional value at a very competitive price per serving. The formula delivers a level of nutrient activity that represents a benchmark for the once-daily category.

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Goals

Impact
Highest effect
A+ Goal FitA+ Strength of SupportA+ CoverageA+ Formula Quality

Chelated Zinc, Selenium complex, and a methylated B-complex provide an elite-level foundation for daily vitality and systemic health. Ingredients like Quercetin Phytosome and Crominex 3+ ensure that metabolic and antioxidant pathways are supported with high biological activity.

This one-per-day formulation appears well-aligned with requirements for maintaining foundational health by filling a vast array of nutrient gaps. The inclusion of trace minerals like Boron and Molybdenum at meaningful doses ensures comprehensive support for structural and metabolic resilience.

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Impact
Highest effect
A Goal FitA+ Strength of SupportA CoverageA Formula Quality

This multivitamin provides essential minerals like zinc and selenium to support skin repair and oxidative defense.

Including lycopene and foundational vitamins helps maintain a healthy skin barrier and supports natural cellular turnover.

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Impact
Highest effect
A- Goal FitA+ Strength of SupportA CoverageA Formula Quality

Bioactive B-vitamins such as P-5-P and Methylcobalamin are provided alongside antioxidants like Alpha Lipoic Acid and Apigenin to support foundational brain health. These ingredients may contribute to energy metabolism and protection against oxidative stress in neural tissues.

Potent doses of 75mg for B1 and B6 provide therapeutic levels of metabolic support. The inclusion of Apigenin and Quercetin addresses the secondary pathways of neuroprotection and mental calm.

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Impact
Highest effect
A Goal FitA+ Strength of SupportA- CoverageA Formula Quality

High-potency B-vitamins, iodine, and zinc form the core of this daily multivitamin formulation. Bioavailable methylcobalamin and methylfolate are utilized to maximize nutrient absorption and utility.

Robust doses of metabolic cofactors directly support cellular energy production and focus. It appears well aligned for those seeking comprehensive daily vitality support through foundational nutrient optimization.

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Impact
Highest effect
A Goal FitA- Strength of SupportA- CoverageA+ Formula Quality

Providing a synergistic blend of lutein, zeaxanthin, and high-dose zinc appears well aligned with goals for macular health and light filtration. These ingredients directly support the pigment density required to protect the retina from high-energy visible light.

The inclusion of comprehensive antioxidants such as vitamins C and E provides further defense against oxidative damage in ocular tissues. Utilizing a one-per-day format with standardized carotenoid yields ensures reliable and bioavailable foundational vision maintenance.

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Impact
Highest effect
A Goal FitA- Strength of SupportA CoverageA Formula Quality

This advanced one-per-day multivitamin provides clinical levels of selenium and 470 mg of Vitamin C to support systemic antioxidant capacity. It also features bio-quercetin phytosome and apigenin to downregulate pro-inflammatory signaling pathways like NF-kB.

L-OptiZinc and lycopene appear well-aligned for providing targeted immune and antioxidant support for cellular resilience. This formulation addresses multiple biological pathways simultaneously to manage chronic low-grade inflammation.

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Ingredients

IngredientAmount per serving
Vitamin A (Beta-Carotene, Vitamin A Acetate)
1500 mcg RAE
Vitamin C (Ascorbic Acid, Calcium Ascorbate, Niacinamide Ascorbate)
470 mg
Vitamin D3 (Cholecalciferol)
50 mcg
Vitamin E (D-Alpha-Tocopherol, D-Alpha-Tocopheryl Succinate)
67 mg
Thiamine (Thiamine Hydrochloride, Vitamin B1)
75 mg
Riboflavin (Riboflavin 5-Phosphate)
50 mg
Niacin (Niacinamide, Niacinamide Ascorbate)
50 mg NE
Vitamin B6 (Pyridoxal 5-Phosphate, Pyridoxine Hydrochloride)
75 mg
Folate (L-5-Methyltetrahydrofolate, Calcium Salt)
680 mcg DFE
Vitamin B12 (Methylcobalamin)
300 mcg
Biotin
300 mcg
Pantothenic Acid (D-Calcium Pantothenate)
50 mg
Iodine (Potassium Iodide)
150 mcg
Magnesium (Magnesium Oxide)
100 mg
Zinc (L-OptiZinc Zinc Mono-L-Methionine Sulfate, Zinc Citrate)
25 mg
Selenium (Se-Methyl L-Selenocysteine, SelenoExcell High Selenium Yeast, Sodium Selenite)
200 mcg
Manganese (Manganese Citrate, Manganese Gluconate)
2 mg
Chromium (Crominex 3+ Chromium)
200 mcg
Molybdenum (Molybdenum Amino Acid Chelate)
100 mcg
Inositol
50 mg
Alpha Lipoic Acid
25 mg
natural Mixed Tocopherols (Alpha-Tocopherol, Beta-Tocopherol, Delta Tocopherol, Gamma-Tocopherol)
20 mg
Bio-Quercetin Phytosome
15 mg
Marigold extract
11.12 mg
Apigenin
5 mg
Boron (Boron Amino Acid Chelate)
3 mg
Lycopene (LycoBeads natural Tomato extract)
1 mg
Gluten Free Adults 18–50
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
Life Extension One-Per-Day offers top-tier value by pairing bioavailable iodine with significant thyroid cofactors. Its single-tablet delivery and high transparency make it a highly efficient option.
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value
This daily multivitamin features a sophisticated selenium complex for broad-spectrum antioxidant coverage. It provides a standardized dose in a convenient one-per-day format, though it comes at a higher price than simple minerals.
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB Value
This popular one-per-day multivitamin includes a high-quality trademarked form of chromium for blood sugar support. It offers a balanced profile of vitamins and minerals for overall health and metabolic efficiency.
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