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B-Complex '50'

Solgar
4.8
★ ★ ★ ★ ★
(8647 ratings)
Vitamin B6 50 mg
Niacin 50 mg
Riboflavin 50 mg
Thiamin 50 mg
Vitamin B5 50 mg
Choline 21 mg
Product Image
Score74
Complete high-potency coverage is convenient, but the formula uses basic forms and too much B6 for casual long-term use. Choline is present only as a minor add-on.
How scoring works
Quantity:100 Capsule(s) • (100 servings)
Goals:
Energy
Metabolism Boost

Score 74

Complete high-potency coverage is convenient, but the formula uses basic forms and too much B6 for casual long-term use. Choline is present only as a minor add-on.
How scoring works
$11.96($0.11 per serving)
Vitacost
$ 12.89
iHerb
$ 11.96
Daily Vita
$ 14.02
Pure Formulas
$ 12.74
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Analysis

The capsule supplies a full high-potency B complex with most major nutrients near the 50 mg level. Folate, B12, D-biotin, pantothenic acid, choline, and inositol round out the formula.

Ingredient forms are mostly basic, including thiamine mononitrate, pyridoxine hydrochloride, and cyanocobalamin. The small choline amount is unlikely to provide meaningful standalone cognitive or liver support.

Vitamin B6 at 50 mg is the central safety trade-off and outweighs the convenience of a one-capsule serving for routine use. Adults who want a long-term B complex should favor a much lower B6 amount and better folate and B12 forms.

Who is it for
  • Adults seeking a concentrated one-capsule B complex
  • People using high-potency B vitamins for a limited period
  • Users who do not require active folate or B12
Best for
  • Short-term high-potency B coverage
  • One-capsule convenience
  • Broad metabolic nutrient supplementation

Pros

  • Provides all core B vitamins
  • Uses D-biotin
  • Includes choline and inositol
  • Requires one capsule per serving

Cons

  • Contains 50 mg of vitamin B6
  • Uses pyridoxine hydrochloride and cyanocobalamin
  • Folate form is not identified
  • Choline is only 21 mg

Warnings

  • The 50 mg vitamin B6 amount may cause tingling, numbness, or other nerve symptoms with prolonged daily use.
  • Avoid stacking it with other B6-containing supplements because the serving is already high.

Nutrient quality

65 Moderate impact

The formula relies on pyridoxine hydrochloride, cyanocobalamin, and other conventional B-vitamin forms. The high vitamin B6 amount creates a meaningful neuropathy concern with long-term use.

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Ingredient transparency

79 High impact

Named vitamins have exact amounts, while the herbal blend components do not. A small herbal blend hides its ingredients, though it is not central to the formula.

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Customer satisfaction

73 High impact

The supplied aggregate rating is very strong. No complaint themes or purpose-specific experience details are supplied.

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Value for money

77 High impact

The formula offers reasonable value despite important quality or dose trade-offs. The tiny herbal blend and modest choline add little to the core formula.

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Goals

Energy
Impact
Highest effect
B+ Goal FitB+ Strength of SupportC+ CoverageA Formula Quality
Vitamin B5 · 50 mgRiboflavin · 50 mgThiamin · 50 mgVitamin B12 · 50 mcg

A focused B-complex directly supports the nutrient-dependent steps of energy metabolism. High thiamin and riboflavin with pantothenate and the wider B-vitamin family provide meaningful pathway depth.

The formula does not provide caffeine, a well-dosed adaptogen, creatine, or a high vitamin B12 amount for broader or acute effects. It is a coherent metabolic-support option rather than a fast-acting energy product.

Study evidence
Riboflavin Mixed 6 studies
Thiamin Disputed 12 studies
Metabolism Boost
Impact
Moderate effect
D Goal FitB Strength of SupportD+ CoverageB Formula Quality
Biotin · 50 mcgNiacin · 50 mgVitamin B12 · 50 mcgRiboflavin · 50 mgThiamin · 50 mgVitamin B5 · 50 mgVitamin B6 · 50 mg

High-potency B vitamins support normal cellular energy reactions. The single-capsule formula is simple and clearly quantified.

Standard forms provide no specialized metabolic delivery, and no thermogenic, thyroid, or glycemic active is included. Its role is nutrient support rather than a direct increase in metabolic rate.

Ingredients

IngredientAmount per serving
Thiamine (Thiamine Mononitrate, Vitamin B1)
50 mg
Riboflavin (Vitamin B2)
50 mg
Niacin (Niacinamide, Vitamin B3)
50 mg
Vitamin B6 (Pyridoxine Hydrochloride)
50 mg
Folate
666 mcg DFE
Vitamin B12 (Cyanocobalamin)
50 mcg
Biotin (D-Biotin)
50 mcg
Pantothenic Acid (D-Calcium Pantothenate, Vitamin B5)
50 mg
Choline (Choline Bitartrate)
21 mg
Inositol
50 mg
Herbal Powdered Blend
3.5 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Halal Vegetarian
Report overview
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Pyridoxine hydrochloride needs conversion to active B6, though riboflavin is present as a supporting cofactor. The 50 mg dose reaches the upper edge of the preferred range in a practical single capsule. Very low serving cost makes the formula economical.

B+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyC Value

The B-complex uses clearly named niacinamide at a useful general-support amount. A standard capsule offers no special release control, but niacinamide itself has low flush potential. The serving cost is favorable for the included B-vitamin profile.

D- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Standard riboflavin requires enzymatic conversion before it becomes metabolically active, while the capsule should dissolve readily. The amount reaches the high-potency range for metabolic support. The low serving cost makes the clearly stated dose highly efficient.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. Disorders of flavin adenine dinucleotide metabolism: MADD and related deficiencies.
    Mereis M; Wanders RJA; Schoonen M; Dercksen M; Smuts I; van der Westhuizen FH · The international journal of biochemistry & cell biology · 2024
    Systematic reviewMetabolism Boost forRiboflavin
  4. Riboflavin and riboflavin-derived cofactors in adolescent girls with anorexia nervosa.
    Capo-chichi CD; Guéant JL; Lefebvre E; Bennani N; Lorentz E; Vidailhet C; Vidailhet M · The American journal of clinical nutrition · 1999
    Clinical trial34 participantsMetabolism Boost forRiboflavin
  5. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  6. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  7. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy forRiboflavin
  8. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  9. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  10. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  11. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  12. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin