Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Calcium supplementation during pregnancy and maternal and offspring bone health: a systematic review and meta-analysis.
Tihtonen K; Korhonen P; Isojärvi J; Ojala R; Ashorn U; Ashorn P; Tammela O · Annals of the New York Academy of Sciences · 2022
Meta-analysis1,566 participants7 studies pooledflagBone Health forscienceCalcium
- Calcium supplementation and bone mineral density in postmenopausal women using estrogen replacement therapy.
Haines CJ; Chung TK; Leung PC; Hsu SY; Leung DH · Bone · 1995
Randomized trialflagBone Health forscienceCalcium
- Calcium supplementation provides an extended window of opportunity for bone mass accretion after menarche.
Rozen GS; Rennert G; Dodiuk-Gad RP; Rennert HS; Ish-Shalom N; Diab G; Raz B; Ish-Shalom S · The American journal of clinical nutrition · 2003
Randomized trial100 participantsflagBone Health forscienceCalcium
- Relationship between bone mineral density changes and risk of fractures among patients receiving calcium with or without vitamin D supplementation: a meta-regression.
Rabenda V; Bruyère O; Reginster JY · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2011
Meta-analysis47,365 participants15 studies pooledflagBone Health forscienceCalcium
- Treatment with alendronate plus calcium, alendronate alone, or calcium alone for postmenopausal low bone mineral density.
Bonnick S; Broy S; Kaiser F; Teutsch C; Rosenberg E; DeLucca P; Melton M · Current medical research and opinion · 2007
Randomized trial701 participantsflagBone Health forscienceCalcium
- One-carbon metabolism-related compounds are associated with epigenetic aging biomarkers: results from the cross-sectional National Health and Nutrition Examination Survey 1999-2002.
Bozack AK; Khodasevich D; Nwanaji-Enwerem JC; Gladish N; Shen H; Daredia S; Gamble M; Needham BL; Rehkopf DH; Cardenas A · The American journal of clinical nutrition · 2025
Cross-sectional study2,346 participantsflagAnti-Aging forscienceFolate
- Longitudinal associations of one-carbon metabolism biomarkers with biological and epigenetic aging in older adults in India.
Wang J; Crimmins E; Kim JK; Chang NS; Dey S; Lee J; Thyagarajan B; Vivek S · GeroScience · 2026
Cohort studyflagAnti-Aging forscienceFolate
- Associations between leukocyte telomere length and three measures of folate status: a cross-sectional analysis of NHANES 1999-2002.
Xue Q; Chen H · Frontiers in nutrition · 2026
Cross-sectional study7,324 participantsflagAnti-Aging forscienceFolate
- Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging.
Kado DM; Karlamangla AS; Huang MH; Troen A; Rowe JW; Selhub J; Seeman TE · The American journal of medicine · 2005
Cohort study499 participantsflagAnti-Aging forscienceFolate
- Blood folate is associated with asymptomatic or partially symptomatic Alzheimer's disease in the Nun study.
Wang H; Odegaard A; Thyagarajan B; Hayes J; Cruz KS; Derosiers MF; Tyas SL; Gross MD · Journal of Alzheimer's disease : JAD · 2012
Cohort study60 participantsflagAnti-Aging forscienceFolate
- Selenium Concentrations and Mortality among Community-Dwelling Older Adults: Results from IlSIRENTE Study.
Giovannini S; Onder G; Lattanzio F; Bustacchini S; Di Stefano G; Moresi R; Russo A; Bernabei R; Landi F · The journal of nutrition, health & aging · 2019
Cohort study347 participantsflagAnti-Aging forscienceSelenium
- Selenium and mortality in the elderly: results from the EVA study.
Akbaraly NT; Arnaud J; Hininger-Favier I; Gourlet V; Roussel AM; Berr C · Clinical chemistry · 2005
Randomized trialflagAnti-Aging forscienceSelenium
- Association of dietary selenium intake and all-cause mortality of Parkinson's disease and its interaction with blood cadmium level: a retrospective cohort study.
Tu X; Wu N; Wan Y; Gan J; Liu Z; Song L · BMC geriatrics · 2024
Cohort study184 participantsflagAnti-Aging forscienceSelenium
- Selenium alleviates cadmium-induced biological aging acceleration and the potential mediating role of inflammation.
Li C; Xiang Y; Liu M; Wang Z; Wu Y; Yang Q; Huang L · Ecotoxicology and environmental safety · 2025
Cross-sectional study7,433 participantsflagAnti-Aging forscienceSelenium
- Minerals and Sarcopenia; The Role of Calcium, Iron, Magnesium, Phosphorus, Potassium, Selenium, Sodium, and Zinc on Muscle Mass, Muscle Strength, and Physical Performance in Older Adults: A Systematic Review.
van Dronkelaar C; van Velzen A; Abdelrazek M; van der Steen A; Weijs PJM; Tieland M · Journal of the American Medical Directors Association · 2019
Systematic review10 studies pooledflagAnti-Aging forscienceSelenium
- Joint association of serum 25-hydroxyvitamin D concentration and body mass index on the acceleration of clinical biomarker-based biological aging.
Pan Z; Zeng J; Chen Z; Chen S; Yang J; Li H; Wang S; Wang J; Li N; Gong Y; Liu M; Li C · The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
Cohort study389,217 participantsflagAnti-Aging forscienceVitamin D
- Serum 25-Hydroxyvitamin D Levels as an Aging Marker: Strong Associations With Age and All-Cause Mortality Independent From Telomere Length, Epigenetic Age Acceleration, and 8-Isoprostane Levels.
Schöttker B; Hagen L; Zhang Y; Gào X; Holleczek B; Gao X; Brenner H · The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
Cohort study9,940 participantsflagAnti-Aging forscienceVitamin D
- Sex-specific associations of serum 25-hydroxyvitamin D concentrations with incident sarcopenia in older adults: A 2-year follow-up study.
Song S; Lim JY; Kim M; Won CW; Park HY · The journal of nutrition, health & aging · 2025
Cohort study1,292 participantsflagAnti-Aging forscienceVitamin D
- Vitamin D deficit is associated with accelerated brain aging in the general population.
Terock J; Bonk S; Frenzel S; Wittfeld K; Garvert L; Hosten N; Nauck M; Völzke H; Van der Auwera S; Grabe HJ · Psychiatry research. Neuroimaging · 2022
Cross-sectional study1,865 participantsflagAnti-Aging forscienceVitamin D
- Vitamin D intake is associated with dementia risk in the Washington Heights-Inwood Columbia Aging Project (WHICAP).
Zhao C; Tsapanou A; Manly J; Schupf N; Brickman AM; Gu Y · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
Cohort study1,759 participantsflagAnti-Aging forscienceVitamin D
- Low dietary vitamin E intake is associated with high risk of incident dementia among older adults: The Shanghai Aging Study.
Liu S; Luo J; Xiao Z; Wu W; Liang X; Ding S; Zhao Q; Zhao X; Wang Y; Ding D · Frontiers in nutrition · 2024
Cohort study1,550 participantsflagAnti-Aging forscienceVitamin E
- Nutrients and bioactives in green leafy vegetables and cognitive decline: Prospective study.
Morris MC; Wang Y; Barnes LL; Bennett DA; Dawson-Hughes B; Booth SL · Neurology · 2019
Cohort study960 participantsflagAnti-Aging forscienceVitamin E
- Low Intake of Vitamin E Accelerates Cellular Aging in Patients With Established Cardiovascular Disease: The CORDIOPREV Study.
Corina A; Rangel-Zúñiga OA; Jiménez-Lucena R; Alcalá-Díaz JF; Quintana-Navarro G; Yubero-Serrano EM; López-Moreno J; Delgado-Lista J; Tinahones F; Ordovás JM; López-Miranda J; Pérez-Martínez P · The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
Observational study1,002 participantsflagAnti-Aging forscienceVitamin E
- The L-shaped link between total antioxidant capacity and phenotypic age acceleration: evidence from NHANES 2003-2010.
Wu Y; Xiang M; Zhao Y; Zhang Y; Cheng W; Deng J · Biogerontology · 2025
Cross-sectional study16,395 participantsflagAnti-Aging forscienceVitamin E
- Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults.
Mangialasche F; Solomon A; Kåreholt I; Hooshmand B; Cecchetti R; Fratiglioni L; Soininen H; Laatikainen T; Mecocci P; Kivipelto M · Experimental gerontology · 2014
Cohort study140 participantsflagAnti-Aging forscienceVitamin E
- Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
Zhou A; Hyppönen E · International journal of epidemiology · 2023
Observational study294,970 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
Randomized trial120 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
Randomized trial120 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
Cross-sectional study9,809 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
Cohort study3,072 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
Randomized trial110 participantsflagAnti-Inflammatory Support forscienceVitamin E
- Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
Meta-analysis495 participants12 studies pooledflagAnti-Inflammatory Support forscienceVitamin E
- Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
Meta-analysis46 studies pooledflagAnti-Inflammatory Support forscienceVitamin E
- Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
Meta-analysis8 studies pooledflagAnti-Inflammatory Support forscienceVitamin E
- Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
Randomized trial71 participantsflagAnti-Inflammatory Support forscienceVitamin E
- What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
Manoj P; Derwin R; George S · International journal of older people nursing · 2023
Meta-analysis12,620 participants7 studies pooledflagBone Health forscienceCalcium
- Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
Randomized trial60 participantsflagBone Health forscienceCalcium
- The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
Randomized trial168 participantsflagBone Health forscienceCalcium
- The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
Randomized trial404 participantsflagBone Health forscienceCalcium
- Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
Randomized trial149 participantsflagBone Health forscienceCalcium
- Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES.
Ling R; Ai Y; Chen C; Zhang J; Zou Z; Cheng S; Li C; Li X; Wang B · Metabolites · 2023
Cross-sectional study2,640 participantsflagBone Health forscienceManganese
- The Manganese-Bone Connection: Investigating the Role of Manganese in Bone Health.
Taskozhina G; Batyrova G; Umarova G; Issanguzhina Z; Kereyeva N · Journal of clinical medicine · 2024
Narrative reviewflagBone Health forscienceManganese
- Associations of multiple metals with bone mineral density: A population-based study in US adults.
Wei MH; Cui Y; Zhou HL; Song WJ; Di DS; Zhang RY; Huang Q; Liu JA; Wang Q · Chemosphere · 2021
Cross-sectional studyflagBone Health forscienceManganese
- Sex-specific associations of urinary mixed-metal concentrations with femoral bone mineral density among older people: an NHANES (2017-2020) analysis.
Li H; Li G; Yi M; Zhou J; Deng Y; Huang Y; He S; Meng X; Liu L · Frontiers in public health · 2024
Cross-sectional study31 participantsflagBone Health forscienceManganese
- Relationship between blood manganese and bone mineral density and bone mineral content in adults: A population-based cross-sectional study.
Wang C; Zhu Y; Long H; Ou M; Zhao S · PloS one · 2022
Cross-sectional study9,732 participantsflagBone Health forscienceManganese
- Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
Randomized trial454 participantsflagBone Health forscienceVitamin D
- Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
Narrative reviewflagBone Health forscienceVitamin D
- Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
Meta-analysis1,786 participants20 studies pooledflagBone Health forscienceVitamin D
- Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
Randomized trial193 participantsflagBone Health forscienceVitamin D
- Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
Rasool N; Munir Y · European journal of clinical nutrition · 2026
Randomized trial612 participantsflagBone Health forscienceVitamin D
- Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
Meta-analysis13 studies pooledflagBone Health forscienceVitamin K
- Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
Randomized trial244 participantsflagBone Health forscienceVitamin K
- Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
Randomized trial92 participantsflagBone Health forscienceVitamin K
- Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
Meta-analysis6,853 participants9 studies pooledflagBone Health forscienceVitamin K
- Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
Randomized trial48 participantsflagBone Health forscienceVitamin K
- Association of radioactive iodine treatment with survivorship symptoms and primary care utilisation in women of reproductive age with thyroid cancer: a retrospective cohort study.
Devanarayan P; Hartman M; Partin M · Family medicine and community health · 2026
Cohort study10,882 participantsflagEnergy forscienceIodine
- Energy level and fatigue after surgery for thyroid cancer: A population-based study of patient-reported outcomes.
Hughes DT; Reyes-Gastelum D; Kovatch KJ; Hamilton AS; Ward KC; Haymart MR · Surgery · 2020
Cohort study2,584 participantsflagEnergy forscienceIodine
- Health-Related Quality of Life in Differentiated Thyroid Cancer Survivors: A Cross-Sectional Study From Turkey.
Gültekin A; Kahraman MY; Şengöz T; Şimşek FS · Head & neck · 2026
Cross-sectional study202 participantsflagEnergy forscienceIodine
- Large-dose intravenous ferric carboxymaltose injection for iron deficiency anemia in heavy uterine bleeding: a randomized, controlled trial.
Van Wyck DB; Mangione A; Morrison J; Hadley PE; Jehle JA; Goodnough LT · Transfusion · 2010
Randomized trial477 participantsflagEnergy forscienceIron
- The Effect of Parenteral or Oral Iron Supplementation on Fatigue, Sleep, Quality of Life and Restless Legs Syndrome in Iron-Deficient Blood Donors: A Secondary Analysis of the IronWoMan RCT.
Macher S; Herster C; Holter M; Moritz M; Matzhold EM; Stojakovic T; Pieber TR; Schlenke P; Drexler C; Amrein K · Nutrients · 2021
Randomized trial176 participantsflagEnergy forscienceIron
- Ferric carboxymaltose vs. oral iron in the treatment of pregnant women with iron deficiency anemia: an international, open-label, randomized controlled trial (FER-ASAP).
Breymann C; Milman N; Mezzacasa A; Bernard R; Dudenhausen J; FER-ASAP investigators · Journal of perinatal medicine · 2018
Randomized trial252 participantsflagEnergy forscienceIron
- Effect of iron therapy on fatigue symptoms in non-anaemic iron deficient women of reproductive age- A Randomized Controlled Trial.
Sultana N; Bajwa FA; Sikandar MZ; Haider MM; Majeed T · JPMA. The Journal of the Pakistan Medical Association · 2026
Randomized trial164 participantsflagEnergy forscienceIron
- Intravenous iron isomaltoside treatment of women suffering from severe fatigue after postpartum hemorrhage.
Holm C; Thomsen LL; Langhoff-Roos J · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019
Randomized trial85 participantsflagEnergy forscienceIron
- Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
Cohort study55,569 participantsflagGeneral Health forscienceFolate
- The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
Randomized trial119 participantsflagGeneral Health forscienceFolate
- Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
Song S; Song BM; Park HY · The Journal of nutrition · 2023
Cohort study21,260 participantsflagGeneral Health forscienceFolate
- The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
Seyoum Tola F · Medicine · 2024
Systematic reviewflagGeneral Health forscienceFolate
- Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
Systematic review71,847 participants46 studies pooledflagGeneral Health forscienceFolate
- Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
Meta-analysis95 participants20 studies pooledflagGeneral Health forscienceSelenium
- Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
Meta-analysis507,251 participants41 studies pooledflagGeneral Health forscienceSelenium
- The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
Meta-analysis4 studies pooledflagGeneral Health flagVision Support forscienceSelenium
- Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
Cohort study6,155 participantsflagGeneral Health forscienceSelenium
- Updates on clinical studies of selenium supplementation in radiotherapy.
Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
Systematic review16 studies pooledflagGeneral Health forscienceSelenium
- Vitamin D supplementation for prevention of mortality in adults.
Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
Meta-analysis95,286 participants159 studies pooledflagGeneral Health forscienceVitamin D
- Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
Randomized trial90 participantsflagGeneral Health forscienceVitamin D
- The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
Meta-analysis2,495 participants19 studies pooledflagGeneral Health forscienceVitamin D
- Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
Systematic review84 studies pooledflagGeneral Health forscienceVitamin D
- Meta-analysis of long-term vitamin D supplementation on overall mortality.
Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
Meta-analysis42 studies pooledflagGeneral Health forscienceVitamin D
- Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
Randomized trial144 participantsflagGeneral Health forscienceZinc
- Zinc supplementation in young children with acute diarrhea in India.
Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
Randomized trial937 participantsflagGeneral Health forscienceZinc
- Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
Randomized trial4,753 participantsflagGeneral Health forscienceZinc
- Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
Randomized trial84 participantsflagGeneral Health forscienceZinc
- Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
Randomized trial142 participantsflagGeneral Health forscienceZinc
- The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
Patel MN; Maheshvari J; Patel N · Cureus · 2025
Randomized trial105 participantsflagHair Health flagNail Health flagSkin Health forscienceBiotin
- Low serum biotinidase activity in children with valproic acid monotherapy.
Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
Clinical trial125 participantsflagHair Health flagSkin Health forscienceBiotin
- Vitamins A, B, C, and D: A Short Review for the Dermatologist.
Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
Narrative reviewflagHair Health forscienceBiotin
- The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
Narrative reviewflagHair Health forscienceBiotin
- Menkes disease and response to copper histidine: An Indian case series.
Yoganathan S; Sudhakar SV; Arunachal G; Thomas M; Subramanian A; George R; Danda S · Annals of Indian Academy of Neurology · 2022
Case series4 participantsflagHair Health forscienceCopper
- Trace element levels in alopecia areata.
Bhat YJ; Manzoor S; Khan AR; Qayoom S · Indian journal of dermatology, venereology and leprology · 2009
Case-control study100 participantsflagHair Health forscienceCopper
- UV damage to hair and the effect of antioxidants and metal chelators.
Millington KR; Marsh JM · International journal of cosmetic science · 2021
In vitro / ex vivo studyflagHair Health forscienceCopper
- Preserving fibre health: reducing oxidative stress throughout the life of the hair fibre.
Marsh JM; Davis MG; Lucas RL; Reilman R; Styczynski PB; Li C; Mamak M; McComb DW; Williams RE; Godfrey S; Navqi KR; Chechik V · International journal of cosmetic science · 2016
In vitro / ex vivo studyflagHair Health forscienceCopper
- Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
Zhang W; Fan M; Wang C; Mahawar K; Parmar C; Chen W; Yang W; Global Bariatric Research Collaborative · Obesity surgery · 2021
Meta-analysis2,538 participants18 studies pooledflagHair Health forscienceFolate
- Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
Case-control study200 participantsflagHair Health forscienceFolate
- Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
Saini A; Norman AR; Cunningham D; Chau I; Hill M; Tait D; Hickish T; Iveson T; Lofts F; Jodrell D; Ross PJ; Oates J · British journal of cancer · 2003
Randomized trialflagHair Health forscienceFolate
- Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer.
Jonker D; Rumble RB; Maroun J; Gastrointestinal Cancer Disease Site Groupof Cancer Care Ontario’s Program in Evidence-Based Care · Current oncology (Toronto, Ont.) · 2012
Randomized trialflagHair Health forscienceFolate
- Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden.
Nolè F; de Braud F; Aapro M; Minchella I; De Pas TM; Zampino MG; Monti S; Andreoni G; Goldhirsch A · Annals of oncology : official journal of the European Society for Medical Oncology · 1997
Randomized trialflagHair Health forscienceFolate
- [Evaluation of the role of dietary intake in the occurrence of alopecia].
El Fékih N; Kamoun H; Fazaa B; El Ati J; Zouari B; Kamoun MR; Gaigi S · Revue medicale de Liege · 2010
Case-control study272 participantsflagHair Health forscienceIodine
- The Association Between Alopecia Areata and Iron Deficiency Anemia: A Large-Scale Population-Based Case-Control Study.
Davidovici B; Drutin Y; Ben-Tov A; Mimouni D; Wohl Y · Journal of personalized medicine · 2026
Case-control study100,203 participantsflagHair Health forscienceIron
- Iron Deficiency and Nonscarring Alopecia in Women: Systematic Review and Meta-Analysis.
Treister-Goltzman Y; Yarza S; Peleg R · Skin appendage disorders · 2022
Meta-analysis10,029 participants36 studies pooledflagHair Health forscienceIron
- Comparative Analysis of Postoperative Hair Loss and Micronutrient Deficiencies After One-Anastomosis Gastric Bypass Versus Sleeve Gastrectomy.
Chinisaz F; Maleki T; Najjari K; Miratashi Yazdi SA · Obesity surgery · 2026
Cohort study261 participantsflagHair Health forscienceIron
- Assessment of Serum Ferritin Levels in Female Patients With Telogen Effluvium.
Thamotharan N; Harikumar MV; Sundaram M; Swaminathan A; Rangarajan S · Cureus · 2026
Cross-sectional study100 participantsflagHair Health forscienceIron
- Diagnosis and treatment of female alopecia: Focusing on the iron deficiency-related alopecia.
Lin CS; Chan LY; Wang JH; Chang CH · Tzu chi medical journal · 2023
Cohort study155 participantsflagHair Health forscienceIron
- Increased prevalence of vitamin D deficiency in patients with alopecia areata: a systematic review and meta-analysis.
Lee S; Kim BJ; Lee CH; Lee WS · Journal of the European Academy of Dermatology and Venereology : JEADV · 2018
Meta-analysis2,039 participants14 studies pooledflagHair Health forscienceVitamin D
- Intralesional vitamin D3 in treatment of alopecia areata: A randomized controlled clinical trial.
Rashad AF; Elgamal E; Fouda I · Journal of cosmetic dermatology · 2022
Randomized trial60 participantsflagHair Health forscienceVitamin D
- Vitamin D and its Analogs in Treatment of Mild to Moderate Alopecia Areata: Systematic Review and Meta-Analysis.
Alsaati AA; Kaliyadan F; Alsaadoun D; Alzakry LM; Alzabadin RA; Hakami TH; Rubaian NFB · Indian dermatology online journal · 2025
Meta-analysisflagHair Health forscienceVitamin D
- Topical calcipotriol vs narrowband ultraviolet B in treatment of alopecia areata: a randomized-controlled trial.
El Taieb MA; Hegazy EM; Ibrahim HM; Osman AB; Abualhamd M · Archives of dermatological research · 2020
Randomized trial60 participantsflagHair Health forscienceVitamin D
- Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.
Chen Y; Dong X; Wang Y; Li Y; Xiong L; Li L · Journal of cosmetic dermatology · 2024
Meta-analysis10,670 participants23 studies pooledflagHair Health forscienceVitamin D
- The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
Randomized trial200 participantsflagHair Health forscienceZinc
- Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
Randomized trialflagHair Health forscienceZinc
- A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
Randomized trial40 participantsflagHair Health forscienceZinc
- BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
Case-control study216 participantsflagHair Health forscienceZinc
- Analysis of serum zinc and copper concentrations in hair loss.
Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
Case-control study342 participantsflagHair Health forscienceZinc
- Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
Randomized trial119 participantsflagImmunity forscienceSelenium
- Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
Randomized trial62 participantsflagImmunity forscienceSelenium
- Chemoprevention trial of human hepatitis with selenium supplementation in China.
Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
Non-randomized trial20,847 participantsflagImmunity forscienceSelenium
- Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
Randomized trial70 participantsflagImmunity forscienceSelenium
- Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
Randomized trial70 participantsflagImmunity forscienceSelenium
- Depressed immune response to tetanus in children with vitamin A deficiency.
Semba RD; Muhilal; Scott AL; Natadisastra G; Wirasasmita S; Mele L; Ridwan E; West KP; Sommer A · The Journal of nutrition · 1992
Randomized trial236 participantsflagImmunity forscienceVitamin A
- Impact of a single megadose of vitamin A at delivery on breastmilk of mothers and morbidity of their infants.
Roy SK; Islam A; Molla A; Akramuzzaman SM; Jahan F; Fuchs G · European journal of clinical nutrition · 1997
Randomized trial50 participantsflagImmunity forscienceVitamin A
- Vitamin A supplementation reduces measles morbidity in young African children: a randomized, placebo-controlled, double-blind trial.
Coutsoudis A; Broughton M; Coovadia HM · The American journal of clinical nutrition · 1991
Randomized trial60 participantsflagImmunity forscienceVitamin A
- Vitamin A supplementation enhances specific IgG antibody levels and total lymphocyte numbers while improving morbidity in measles.
Coutsoudis A; Kiepiela P; Coovadia HM; Broughton M · The Pediatric infectious disease journal · 1992
Randomized trial60 participantsflagImmunity forscienceVitamin A
- Vitamin A supplementation reduces the monocyte chemoattractant protein-1 intestinal immune response of Mexican children.
Long KZ; Santos JI; Estrada Garcia T; Haas M; Firestone M; Bhagwat J; Dupont HL; Hertzmark E; Rosado JL; Nanthakumar NN · The Journal of nutrition · 2006
Randomized trial127 participantsflagImmunity forscienceVitamin A
- Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
Guideline / consensusflagImmunity forscienceVitamin C
- Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
Meta-analysis2,334 participants14 studies pooledflagImmunity forscienceVitamin C
- Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
Meta-analysisflagImmunity forscienceVitamin C
- New evidence for antioxidant properties of vitamin C.
Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
Randomized trial20 participantsflagImmunity forscienceVitamin C
- Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
Calder PC; Kreider RB; McKay DL · Nutrients · 2025
Systematic review13 studies pooledflagImmunity forscienceVitamin C
- Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
Meta-analysis11,321 participants25 studies pooledflagImmunity forscienceVitamin D
- Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
Meta-analysis4,859 participants10 studies pooledflagImmunity forscienceVitamin D
- Vitamin D3 and deconvoluting a rash.
Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
Randomized trial28 participantsflagImmunity forscienceVitamin D
- Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
Randomized trial110 participantsflagImmunity forscienceVitamin D
- Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
Meta-analysis50,554 participants65 studies pooledflagImmunity forscienceVitamin D
- Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
Meta-analysis199,055 participants115 studies pooledflagImmunity forscienceZinc
- Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
Randomized trial609 participantsflagImmunity forscienceZinc
- A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
Randomized trial64 participantsflagImmunity forscienceZinc
- The effect of zinc and vitamin A supplementation on immune response in an older population.
Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
Randomized trial136 participantsflagImmunity forscienceZinc
- The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
Systematic review13 studies pooledflagImmunity forscienceZinc
- Folate and long-chain polyunsaturated fatty acid supplementation during pregnancy has long-term effects on the attention system of 8.5-y-old offspring: a randomized controlled trial.
Catena A; Muñoz-Machicao JA; Torres-Espínola FJ; Martínez-Zaldívar C; Diaz-Piedra C; Gil A; Haile G; Györei E; Molloy AM; Decsi T; Koletzko B; Campoy C · The American journal of clinical nutrition · 2016
Randomized trial136 participantsflagMental Focus forscienceFolate
- Cerebral folate receptor autoantibodies in autism spectrum disorder.
Frye RE; Sequeira JM; Quadros EV; James SJ; Rossignol DA · Molecular psychiatry · 2014
Non-randomized trial93 participantsflagMental Focus forscienceFolate
- Folate, vitamin B-12, and cognitive function in the Boston Puerto Rican Health Study.
Boumenna T; Scott TM; Lee JS; Palacios N; Tucker KL · The American journal of clinical nutrition · 2026
Cross-sectional study1,408 participantsflagMental Focus forscienceFolate
- Vitamins B9 and B12 in children with attention deficit hyperactivity disorder (ADHD).
Razavinia F; Ebrahimiyan A; Faal Siahkal S; Ghazinezhad N; Abedi P · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2024
Meta-analysis982 participants6 studies pooledflagMental Focus forscienceFolate
- Does L-Methylfolate Supplement Methylphenidate Pharmacotherapy in Attention-Deficit/Hyperactivity Disorder?: Evidence of Lack of Benefit From a Double-Blind, Placebo-Controlled, Randomized Clinical Trial.
Surman C; Ceranoglu A; Vaudreuil C; Albright B; Uchida M; Yule A; Spencer A; Boland H; Grossman R; Rhodewalt L; Fitzgerald M; Biederman J · Journal of clinical psychopharmacology · 2019
Randomized trial44 participantsflagMental Focus forscienceFolate
- Iodine supplementation improves cognition in iodine-deficient schoolchildren in Albania: a randomized, controlled, double-blind study.
Zimmermann MB; Connolly K; Bozo M; Bridson J; Rohner F; Grimci L · The American journal of clinical nutrition · 2006
Randomized trial310 participantsflagMental Focus forscienceIodine
- Iodine intake from supplements and diet during pregnancy and child cognitive and motor development: the INMA Mother and Child Cohort Study.
Murcia M; Espada M; Julvez J; Llop S; Lopez-Espinosa MJ; Vioque J; Basterrechea M; Riaño I; González L; Alvarez-Pedrerol M; Tardón A; Ibarluzea J; Rebagliato M · Journal of epidemiology and community health · 2019
Cohort study1,803 participantsflagMental Focus forscienceIodine
- Breastfeeding and maternal and infant iodine nutrition.
Azizi F; Smyth P · Clinical endocrinology · 2009
Systematic review36 studies pooledflagMental Focus forscienceIodine
- Preconception Maternal Iodine Status Is Positively Associated with IQ but Not with Measures of Executive Function in Childhood.
Robinson SM; Crozier SR; Miles EA; Gale CR; Calder PC; Cooper C; Inskip HM; Godfrey KM · The Journal of nutrition · 2019
Cohort study654 participantsflagMental Focus forscienceIodine
- Iodine deficiency: consequences and progress toward elimination.
Maberly GF; Haxton DP; van der Haar F · Food and nutrition bulletin · 2006
Narrative reviewflagMental Focus forscienceIodine
- The Effect of Iron-Fortified Lentils on Blood and Cognitive Status among Adolescent Girls in Bangladesh.
Barnett AL; Wenger MJ; Yunus FM; Jalal C; DellaValle DM · Nutrients · 2023
Randomized trial359 participantsflagMental Focus flagProductivity Boost forscienceIron
- Cognitive Performance in Indian School-Going Adolescents Is Positively Affected by Consumption of Iron-Biofortified Pearl Millet: A 6-Month Randomized Controlled Efficacy Trial.
Scott SP; Murray-Kolb LE; Wenger MJ; Udipi SA; Ghugre PS; Boy E; Haas JD · The Journal of nutrition · 2019
Randomized trial140 participantsflagMental Focus forscienceIron
- Effects of iron supplementation twice a week on attention score and haematologic measures in female high school students.
Rezaeian A; Ghayour-Mobarhan M; Mazloum SR; Yavari M; Jafari SA · Singapore medical journal · 2015
Randomized trial200 participantsflagMental Focus forscienceIron
- Randomised study of cognitive effects of iron supplementation in non-anaemic iron-deficient adolescent girls.
Bruner AB; Joffe A; Duggan AK; Casella JF; Brandt J · Lancet (London, England) · 1996
Randomized trial81 participantsflagMental Focus forscienceIron
- Effect of iron supplementation on cognition in Greek preschoolers.
Metallinos-Katsaras E; Valassi-Adam E; Dewey KG; Lönnerdal B; Stamoulakatou A; Pollitt E · European journal of clinical nutrition · 2005
Randomized trial49 participantsflagMental Focus forscienceIron
- Three Doses of Vitamin D and Cognitive Outcomes in Older Women: A Double-Blind Randomized Controlled Trial.
Castle M; Fiedler N; Pop LC; Schneider SJ; Schlussel Y; Sukumar D; Hao L; Shapses SA · The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
Randomized trialflagMental Focus forscienceVitamin D
- Vitamin D and executive function: a preliminary report.
Hansen AL; Dahl L; Bakke L; Thayer JF · Perceptual and motor skills · 2012
Cross-sectional study25 participantsflagMental Focus forscienceVitamin D
- Effects of Vitamin D Supplementation on Cognitive Function in Older Adults: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE) Methodology-Assessed Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Behrouzi R; Shahinfar H; Jazayeri S · Nutrition reviews · 2026
Meta-analysis9 studies pooledflagMental Focus forscienceVitamin D
- Maternal vitamin D concentrations are associated with faster childhood reaction time and response speed, but not with motor fluency and flexibility, at the age of 5-6 years: the Amsterdam Born Children and their Development (ABCD) Study.
Brouwer-Brolsma EM; Vrijkotte TGM; Feskens EJM · The British journal of nutrition · 2019
Cohort study1,854 participantsflagMental Focus forscienceVitamin D
- Serum 25-hydroxyvitamin D and cognitive decline in the very old: the Newcastle 85+ Study.
Granic A; Hill TR; Kirkwood TB; Davies K; Collerton J; Martin-Ruiz C; von Zglinicki T; Saxby BK; Wesnes KA; Collerton D; Mathers JC; Jagger C · European journal of neurology · 2015
Cohort study775 participantsflagMental Focus forscienceVitamin D
- The efficacy of zinc augmentation in children with attention deficit hyperactivity disorder under treatment with methylphenidate: A randomized controlled trial.
Noorazar SG; Malek A; Aghaei SM; Yasamineh N; Kalejahi P · Asian journal of psychiatry · 2021
Randomized trial60 participantsflagMental Focus forscienceZinc
- Effects of zinc supplementation on parent and teacher behaviour rating scores in low socioeconomic level Turkish primary school children.
Uçkardeş Y; Ozmert EN; Unal F; Yurdakök K · Acta paediatrica (Oslo, Norway : 1992) · 2009
Randomized trial226 participantsflagMental Focus forscienceZinc
- The Role of Iron and Zinc in the Treatment of ADHD among Children and Adolescents: A Systematic Review of Randomized Clinical Trials.
Granero R; Pardo-Garrido A; Carpio-Toro IL; Ramírez-Coronel AA; Martínez-Suárez PC; Reivan-Ortiz GG · Nutrients · 2021
Systematic review9 studies pooledflagMental Focus forscienceZinc
- Does zinc moderate essential fatty acid and amphetamine treatment of attention-deficit/hyperactivity disorder?
Arnold LE; Pinkham SM; Votolato N · Journal of child and adolescent psychopharmacology · 2001
Randomized trialflagMental Focus forscienceZinc
- The effect of zinc supplementation in children with attention deficit hyperactivity disorder: A systematic review and dose-response meta‑analysis of randomized clinical trials.
Talebi S; Miraghajani M; Ghavami A; Mohammadi H · Critical reviews in food science and nutrition · 2022
Meta-analysis489 participants6 studies pooledflagMental Focus forscienceZinc
- Biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
Guideline / consensusflagMetabolism Boost forscienceBiotin
- Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
Perry CA; West AA; Gayle A; Lucas LK; Yan J; Jiang X; Malysheva O; Caudill MA · The Journal of nutrition · 2015
Clinical trial75 participantsflagMetabolism Boost forscienceBiotin
- Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in kermanshah in iran (2008-2009)
Hemmati M, Babaei H, Abdolsalehei M · Oman Medical Journal · 2013
Randomized trial70 participantsflagMetabolism Boost forscienceBiotin
- Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
César A Albarracin, Bobby C Fuqua, James L Evans, Ira D Goldfine · Diabetes/Metabolism Research and Reviews · 2008
Randomized trial348 participantsflagMetabolism Boost forscienceBiotin
- Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia
Cristina Revilla-Monsalve, Iván Zendejas-Ruiz, Sergio Islas-Andrade, Armida Báez-Saldaña, Miguel Angel Palomino-Garibay, Pedro Martín Hernández-Quiróz, Cristina Fernandez-Mejia · Biomedicine & Pharmacotherapy · 2006
Randomized trial33 participantsflagMetabolism Boost forscienceBiotin
- Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes.
Anderson RA; Cheng N; Bryden NA; Polansky MM; Cheng N; Chi J; Feng J · Diabetes · 1997
Randomized trial180 participantsflagMetabolism Boost forscienceChromium
- Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Jamilian M; Asemi Z · Annals of nutrition & metabolism · 2016
Randomized trial64 participantsflagMetabolism Boost forscienceChromium
- A Comprehensive insight into the effect of chromium supplementation on oxidative stress indices in diabetes mellitus: A systematic review.
Kooshki F; Tutunchi H; Vajdi M; Karimi A; Niazkar HR; Shoorei H; Pourghassem Gargari B · Clinical and experimental pharmacology & physiology · 2024
Systematic review33 studies pooledflagMetabolism Boost forscienceChromium
- Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
Meta-analysis2,362 participants41 studies pooledflagMetabolism Boost forscienceChromium
- [Chromium supplementation in patients with type 2 diabetes and high risk of type 2 diabetes: a meta-analysis of randomized controlled trials].
San Mauro-Martin I; Ruiz-León AM; Camina-Martín MA; Garicano-Vilar E; Collado-Yurrita L; Mateo-Silleras Bd; Redondo Del Río Mde P · Nutricion hospitalaria · 2017
Meta-analysis13 studies pooledflagMetabolism Boost forscienceChromium
- Iodine Supplementation Decreases Hypercholesterolemia in Iodine-Deficient, Overweight Women: A Randomized Controlled Trial.
Herter-Aeberli I; Cherkaoui M; El Ansari N; Rohner R; Stinca S; Chabaa L; von Eckardstein A; Aboussad A; Zimmermann MB · The Journal of nutrition · 2015
Randomized trial163 participantsflagMetabolism Boost forscienceIodine
- Effect of oral iodized oil on thyroid size and thyroid hormone metabolism in children with concurrent selenium and iodine deficiency.
Zimmermann MB; Adou P; Torresani T; Zeder C; Hurrell RF · European journal of clinical nutrition · 2000
Single-arm trial51 participantsflagMetabolism Boost forscienceIodine
- Serum Iodine Concentration as a Biomarker for Individual Iodine Nutrition and Thyroid Function in Pregnant Women: A Cross-Sectional Study in Hubei Province.
Xu M; Dai X; Wang Z; Guo C; Zhang B; Guo H · Public health nutrition · 2026
Cross-sectional study1,197 participantsflagMetabolism Boost forscienceIodine
- Iron status influences the efficacy of iodine prophylaxis in goitrous children in Côte d'Ivoire.
Zimmermann MB · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2002
OtherflagMetabolism Boost forscienceIodine
- Persistence of goiter despite oral iodine supplementation in goitrous children with iron deficiency anemia in Côte d'Ivoire.
Zimmermann M; Adou P; Torresani T; Zeder C; Hurrell R · The American journal of clinical nutrition · 2000
Non-randomized trial109 participantsflagMetabolism Boost forscienceIodine
- Effects of vitamin D supplementation on insulin resistance and lipid metabolic profiles in women with gestational diabetes mellitus: A randomized controlled trial.
Duan Y; Zhang S; Ma X; Li L; Jia K · African journal of reproductive health · 2026
Randomized trial120 participantsflagMetabolism Boost forscienceVitamin D
- Vitamin D3 improves glucose metabolism and attenuates inflammation in prediabetic human and mice.
Zhang Y; Ni P; Miao Y; Chen H; Tang L; Song H; Li W; Li X · The Journal of nutritional biochemistry · 2024
Randomized trialflagMetabolism Boost forscienceVitamin D
- Effects of vitamin D and calcium supplementation on pancreatic β cell function, insulin sensitivity, and glycemia in adults at high risk of diabetes: the Calcium and Vitamin D for Diabetes Mellitus (CaDDM) randomized controlled trial.
Mitri J; Dawson-Hughes B; Hu FB; Pittas AG · The American journal of clinical nutrition · 2011
Randomized trial92 participantsflagMetabolism Boost forscienceVitamin D
- The Effects of Vitamin D Supplementation on Glycemic Control, Lipid Profiles and C-Reactive Protein Among Patients with Cardiovascular Disease: a Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Ostadmohammadi V; Milajerdi A; Ghayour-Mobarhan M; Ferns G; Taghizadeh M; Badehnoosh B; Mirzaei H; Asemi Z · Current pharmaceutical design · 2020
Meta-analysis630 participants8 studies pooledflagMetabolism Boost forscienceVitamin D
- The Effect of Improved Serum 25-Hydroxyvitamin D Status on Glycemic Control in Diabetic Patients: A Meta-Analysis.
Mirhosseini N; Vatanparast H; Mazidi M; Kimball SM · The Journal of clinical endocrinology and metabolism · 2017
Meta-analysis1,528 participants24 studies pooledflagMetabolism Boost forscienceVitamin D
- The effect of curcumin and zinc co-supplementation on glycemic parameters in overweight or obese prediabetic subjects: A phase 2 randomized, placebo-controlled trial with a multi-arm, parallel-group design.
Karandish M; Mozaffari-Khosravi H; Mohammadi SM; Cheraghian B; Azhdari M · Phytotherapy research : PTR · 2021
Randomized trial84 participantsflagMetabolism Boost forscienceZinc
- Relationship between zinc and glucose metabolism in Japanese adults.
Suka M; Tsuruta H; Takao T; Yanagisawa H · Diabetology international · 2026
Cross-sectional study533 participantsflagMetabolism Boost forscienceZinc
- Zinc and the Innovative Zinc-α2-Glycoprotein Adipokine Play an Important Role in Lipid Metabolism: A Critical Review.
Banaszak M; Górna I; Przysławski J · Nutrients · 2021
Narrative reviewflagMetabolism Boost forscienceZinc
- Capsaicin and Zinc Signalling Pathways as Promising Targets for Managing Insulin Resistance and Type 2 Diabetes.
Ferdowsi PV; Ahuja KDK; Beckett JM; Myers S · Molecules (Basel, Switzerland) · 2023
Narrative reviewflagMetabolism Boost forscienceZinc
- Zinc and Diabetes: A Connection between Micronutrient and Metabolism.
Ahmad R; Shaju R; Atfi A; Razzaque MS · Cells · 2024
Narrative reviewflagMetabolism Boost forscienceZinc
- Biotin for the treatment of nail disease: what is the evidence?
Lipner SR; Scher RK · The Journal of dermatological treatment · 2018
Narrative reviewflagNail Health forscienceBiotin
- Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy.
Colombo VE; Gerber F; Bronhofer M; Floersheim GL · Journal of the American Academy of Dermatology · 1991
Other32 participantsflagNail Health forscienceBiotin
- Treatment of brittle nail with a hydroxypropyl chitosan-based lacquer, alone or in combination with oral biotin: A randomized, assessor-blinded trial.
Chiavetta A; Mazzurco S; Secolo MP; Tomarchio G; Milani M · Dermatologic therapy · 2020
Randomized trial50 participantsflagNail Health forscienceBiotin
- Vitamins and minerals: their role in nail health and disease.
Scheinfeld N; Dahdah MJ; Scher R · Journal of drugs in dermatology : JDD · 2007
Narrative reviewflagNail Health forscienceBiotin flagNail Health forscienceIron flagNail Health forscienceZinc
- A pilot iron substitution programme in female blood donors with iron deficiency without anaemia.
Pittori C; Buser A; Gasser UE; Sigle J; Job S; Rüesch M; Tichelli A; Infanti L · Vox sanguinis · 2011
Non-randomized trial224 participantsflagNail Health forscienceIron
- Evaluation of nail abnormalities.
Tully AS; Trayes KP; Studdiford JS · American family physician · 2013
Narrative reviewflagNail Health forscienceIron
- Efficacy and tolerability of a biomineral formulation for treatment of onychoschizia: a randomized trial
Adele Sparavigna, Beatrice Tenconi, Laura La Penna · Clinical, Cosmetic and Investigational Dermatology · 2019
Randomized trial48 participantsflagNail Health forscienceIron
- Acute selenium toxicity associated with a dietary supplement.
MacFarquhar JK; Broussard DL; Melstrom P; Hutchinson R; Wolkin A; Martin C; Burk RF; Dunn JR; Green AL; Hammond R; Schaffner W; Jones TF · Archives of internal medicine · 2010
Observational study201 participantsflagNail Health forscienceSelenium
- Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient.
Dunleavy KA; Ungaro RC; Manning L; Gold S; Novak J; Colombel JF · Crohn's & colitis 360 · 2023
Other20 participantsflagNail Health forscienceVitamin C
- Recommendations for the definition, evaluation, and treatment of nail psoriasis in adult patients with no or mild skin psoriasis: A dermatologist and nail expert group consensus.
Rigopoulos D; Baran R; Chiheb S; Daniel CR; Di Chiacchio N; Gregoriou S; Grover C; Haneke E; Iorizzo M; Pasch M; Piraccini BM; Rich P; Richert B; Rompoti N; Rubin AI; Singal A; Starace M; Tosti A; Triantafyllopoulou I; Zaiac M · Journal of the American Academy of Dermatology · 2019
Guideline / consensusflagNail Health forscienceVitamin D
- Vitamins for the Management of Nail Disease: A Literature Review.
Curtis KL; Lipner SR · Skin appendage disorders · 2025
Narrative reviewflagNail Health forscienceVitamin D
- Nail involvement in psoriatic arthritis.
Sobolewski P; Walecka I; Dopytalska K · Reumatologia · 2019
Narrative reviewflagNail Health forscienceVitamin D
- Psoriasis treatment in difficult locations: scalp, nails, and intertriginous areas.
Wozel G · Clinics in dermatology · 2009
Narrative reviewflagNail Health forscienceVitamin D
- Nail psoriasis: clinical presentation and best practice recommendations.
Edwards F; de Berker D · Drugs · 2010
Narrative reviewflagNail Health forscienceVitamin D
- Effects of daily iron supplementation in primary-school-aged children: systematic review and meta-analysis of randomized controlled trials.
Low M; Farrell A; Biggs BA; Pasricha SR · CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2014
Meta-analysis7,089 participants32 studies pooledflagProductivity Boost forscienceIron
- Consumption of Iron-Biofortified Beans Positively Affects Cognitive Performance in 18- to 27-Year-Old Rwandan Female College Students in an 18-Week Randomized Controlled Efficacy Trial.
Murray-Kolb LE; Wenger MJ; Scott SP; Rhoten SE; Lung'aho MG; Haas JD · The Journal of nutrition · 2017
Randomized trial150 participantsflagProductivity Boost forscienceIron
- Functional consequences of iron supplementation in iron-deficient female cotton mill workers in Beijing, China.
Li R; Chen X; Yan H; Deurenberg P; Garby L; Hautvast JG · The American journal of clinical nutrition · 1994
Randomized trial80 participantsflagProductivity Boost forscienceIron
- Daily iron supplementation for improving anaemia, iron status and health in menstruating women.
Low MS; Speedy J; Styles CE; De-Regil LM; Pasricha SR · The Cochrane database of systematic reviews · 2016
Meta-analysis8,506 participants67 studies pooledflagProductivity Boost forscienceIron
- Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters.
Aksac SE; Bilgili SG; Yavuz GO; Yavuz IH; Aksac M; Karadag AS · International journal of dermatology · 2021
Non-randomized trial60 participantsflagSkin Health forscienceBiotin
- Generalized seborrhoeic dermatitis. Clinical and therapeutic data of 25 patients.
Messaritakis J; Kattamis C; Karabula C; Matsaniotis N · Archives of disease in childhood · 1976
Non-randomized trial25 participantsflagSkin Health forscienceBiotin
- Holocarboxylase synthetase deficiency: novel clinical and molecular findings.
Tammachote R; Janklat S; Tongkobpetch S; Suphapeetiporn K; Shotelersuk V · Clinical genetics · 2010
Case series4 participantsflagSkin Health forscienceBiotin
- Noninferiority of Copper Dressings Than Negative Pressure Wound Therapy in Healing Diabetic Wounds: A Randomized Clinical Trial.
Melamed E; Dabbah J; Israel T; Kan I; Pinzur MS; Roth T; Borkow G · Advances in wound care · 2026
Randomized trialflagSkin Health forscienceCopper
- Improvement of facial skin characteristics using copper oxide containing pillowcases: a double-blind, placebo-controlled, parallel, randomized study.
Borkow G; Gabbay J; Lyakhovitsky A; Huszar M · International journal of cosmetic science · 2010
Randomized trial57 participantsflagSkin Health forscienceCopper
- Radially Electrospun Fibrous Membrane Incorporated with Copper Peroxide Nanodots Capable of Self-Catalyzed Chemodynamic Therapy for Angiogenesis and Healing Acceleration of Diabetic Wounds.
Huang Y; Qi L; Liu Z; Jiang Y; Wang J; Liu L; Li Y; Zhang L; Feng G · ACS applied materials & interfaces · 2023
Animal experimentflagSkin Health forscienceCopper
- Engineering copper nanoparticle/polysaccharide-immobilized cotton gauze for accelerated healing of Staphylococcus aureus-infected dermal wounds.
Sahoo M; Banerjee T; Virkar S; Das S; Biswas S; Mitra D · Journal of materials chemistry. B · 2026
Animal experimentflagSkin Health forscienceCopper
- Stimulation of Healing of Non-Infected Stagnated Diabetic Wounds by Copper Oxide-Impregnated Wound Dressings.
Melamed E; Rovitsky A; Roth T; Assa L; Borkow G · Medicina (Kaunas, Lithuania) · 2021
Single-arm trialflagSkin Health forscienceCopper
- Comparative clinical trial of bifonazole solution versus selenium sulphide shampoo in the treatment of pityriasis versicolor.
Chu AC · Dermatologica · 1985
Randomized trial38 participantsflagSkin Health forscienceSelenium
- Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial.
Duffield-Lillico AJ; Slate EH; Reid ME; Turnbull BW; Wilkins PA; Combs GF; Park HK; Gross EG; Graham GF; Stratton MS; Marshall JR; Clark LC; Nutritional Prevention of Cancer Study Group · Journal of the National Cancer Institute · 2003
Randomized trial1,312 participantsflagSkin Health forscienceSelenium
- Evidence-Based Nutritional Interventions in Wound Care.
Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
Systematic review2,339 participants36 studies pooledflagSkin Health forscienceSelenium flagSkin Health forscienceVitamin E flagSkin Health forscienceZinc
- A randomized, double-blind placebo-controlled trial evaluating the effects of vitamin E and selenium on arsenic-induced skin lesions in Bangladesh.
Verret WJ; Chen Y; Ahmed A; Islam T; Parvez F; Kibriya MG; Graziano JH; Ahsan H · Journal of occupational and environmental medicine · 2006
Randomized trial121 participantsflagSkin Health forscienceSelenium
- The Whitening, Moisturizing, Anti-aging Activities, and Skincare Evaluation of Selenium-Enriched Mung Bean Fermentation Broth.
Wei K; Guo C; Zhu J; Wei Y; Wu M; Huang X; Zhang M; Li J; Wang X; Wang Y; Wei X · Frontiers in nutrition · 2022
Clinical trial31 participantsflagSkin Health forscienceSelenium
- Efficacy and Tolerability of Topical 0.1% Stabilized Bioactive Retinol for Photoaging: A Vehicle-Controlled Integrated Analysis.
Farris P; Berson D; Bhatia N; Goldberg D; Lain E; Mariwalla K; Zeichner J; Miller D; McGuire T; Kizoulis M · Journal of drugs in dermatology : JDD · 2024
Meta-analysis471 participants6 studies pooledflagSkin Health forscienceVitamin A
- Tensile properties and contours of aging facial skin. A controlled double-blind comparative study of the effects of retinol, melibiose-lactose and their association.
Piérard-Franchimont C; Castelli D; Cromphaut IV; Bertin C; Ries G; Cauwenbergh G; Piérard GE · Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2016
Randomized trial120 participantsflagSkin Health forscienceVitamin A
- Antiaging action of retinol: from molecular to clinical.
Bellemère G; Stamatas GN; Bruère V; Bertin C; Issachar N; Oddos T · Skin pharmacology and physiology · 2009
Randomized trial48 participantsflagSkin Health forscienceVitamin A
- An Updated Review of Topical Tretinoin in Dermatology: From Acne and Photoaging to Skin Cancer.
Balado-Simó P; Morgado-Carrasco D; Gómez-Armayones S; López-Ferrer A; Barco D; Ferrándiz-Pulido C; Podlipnik S · Journal of clinical medicine · 2025
Narrative reviewflagSkin Health forscienceVitamin A
- Novel Cyclized Hexapeptide-9 Outperforms Retinol Against Skin Aging: A Randomized, Double-Blinded, Active- and Vehicle-Controlled Clinical Trial.
Chang H; Tao K; Yang Y; Wang Y; Ge M; Wang X; Tang S; Yu H · Journal of cosmetic dermatology · 2025
Randomized trialflagSkin Health forscienceVitamin A
- Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
Randomized trial23 participantsflagSkin Health forscienceVitamin C
- Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
Randomized trial149 participantsflagSkin Health forscienceVitamin C
- Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
Randomized trial25 participantsflagSkin Health forscienceVitamin C
- Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
Randomized trial16 participantsflagSkin Health forscienceVitamin C
- Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
Cross-sectional study4,025 participantsflagSkin Health forscienceVitamin C
- Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis.
Javanbakht MH; Keshavarz SA; Djalali M; Siassi F; Eshraghian MR; Firooz A; Seirafi H; Ehsani AH; Chamari M; Mirshafiey A · The Journal of dermatological treatment · 2011
Randomized trial45 participantsflagSkin Health forscienceVitamin E
- Serum vitamin E levels and chronic inflammatory skin diseases: A systematic review and meta-analysis.
Liu X; Yang G; Luo M; Lan Q; Shi X; Deng H; Wang N; Xu X; Zhang C · PloS one · 2022
Meta-analysis20 studies pooledflagSkin Health forscienceVitamin E
- Effects of tocotrienol on aging skin: A systematic review.
Ghazali NI; Mohd Rais RZ; Makpol S; Chin KY; Yap WN; Goon JA · Frontiers in pharmacology · 2022
Systematic reviewflagSkin Health forscienceVitamin E
- Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans.
Stahl W; Heinrich U; Jungmann H; Sies H; Tronnier H · The American journal of clinical nutrition · 2000
Randomized trialflagSkin Health forscienceVitamin E
- Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
Meta-analysis2,088 participants20 studies pooledflagSkin Health forscienceZinc
- Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
Cohort study23 participantsflagSkin Health forscienceZinc
- Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
Randomized trial30 participantsflagSkin Health forscienceZinc
- A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
Randomized trial90 participantsflagSkin Health forscienceZinc
- Influence of folic acid on postprandial endothelial dysfunction.
Wilmink HW; Stroes ES; Erkelens WD; Gerritsen WB; Wever R; Banga JD; Rabelink TJ · Arteriosclerosis, thrombosis, and vascular biology · 2000
Randomized trial20 participantsflagStress Relief forscienceFolate
- The effects of folate supplementation on inflammatory factors and biomarkers of oxidative stress in overweight and obese women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled clinical trial.
Bahmani F; Karamali M; Shakeri H; Asemi Z · Clinical endocrinology · 2015
Randomized trial69 participantsflagStress Relief forscienceFolate
- Folate for depressive disorders: systematic review and meta-analysis of randomized controlled trials.
Taylor MJ; Carney SM; Goodwin GM; Geddes JR · Journal of psychopharmacology (Oxford, England) · 2004
Meta-analysis247 participants3 studies pooledflagStress Relief forscienceFolate
- Depressive symptoms and associated factors among women preparing for pregnancy: a population-based study from the Seoul metropolitan preconception health management program.
Lee HJ; Shin W; Han JY; Choi HZ; Kang J; Woo SY · BMC women's health · 2026
Cross-sectional study14,004 participantsflagStress Relief forscienceFolate
- Folate administration decreases oxidative status and blood pressure in postmenopausal women.
Cagnacci A; Cannoletta M; Xholli A; Piacenti I; Palma F; Palmieri B · European journal of nutrition · 2016
Randomized trial30 participantsflagStress Relief forscienceFolate
- Vitamin D Alleviates Anxiety and Depression in Elderly People with Prediabetes: A Randomized Controlled Study.
Zaromytidou E; Koufakis T; Dimakopoulos G; Drivakou D; Konstantinidou S; Rakitzi P; Grammatiki M; Manthou E; Notopoulos A; Iakovou I; Gotzamani-Psarrakou A; Kotsa K · Metabolites · 2023
Randomized trial90 participantsflagStress Relief forscienceVitamin D
- Effects of an 8-week high-dose vitamin D supplementation on fatigue and neuropsychiatric manifestations in post-COVID syndrome: A randomized controlled trial.
Charoenporn V; Tungsukruthai P; Teacharushatakit P; Hanvivattanakul S; Sriyakul K; Sukprasert S; Kamalashiran C; Tungsukruthai S; Charernboon T · Psychiatry and clinical neurosciences · 2024
Randomized trial80 participantsflagStress Relief forscienceVitamin D
- The Influence of Vitamin D Intake and Status on Mental Health in Children: A Systematic Review.
Głąbska D; Kołota A; Lachowicz K; Skolmowska D; Stachoń M; Guzek D · Nutrients · 2021
Systematic review24 studies pooledflagStress Relief forscienceVitamin D
- Vitamin D3 enhances mood in healthy subjects during winter.
Lansdowne AT; Provost SC · Psychopharmacology · 1998
Randomized trial44 participantsflagStress Relief forscienceVitamin D
- Comparative Effects of Etelcalcetide and Maxacalcitol on Serum Calcification Propensity in Secondary Hyperparathyroidism: A Randomized Clinical Trial.
Shoji T; Nakatani S; Kabata D; Mori K; Shintani A; Yoshida H; Takahashi K; Ota K; Fujii H; Ueda S; Nishi S; Nakatani T; Yoshiyama M; Goto K; Hamada T; Imanishi M; Ishimura E; Kagitani S; Kato Y; Kumeda Y; Maekawa K; Matsumura T; Nagayama H; Obi Y; Ohno Y; Sai Y; Sakurai M; Sasaki S; Shidara K; Shoji S; Tsujimoto Y; Yamakawa K; Yasuda H; Yodoi S; Inaba M; Emoto M · Clinical journal of the American Society of Nephrology : CJASN · 2021
Randomized trial326 participantsflagStress Relief forscienceVitamin D
- Investigating the effect of zinc supplementation on probability of relapse and mental health in patients with opioid use disorder undergoing methadone maintenance treatment.
Amini Z; HeidariFarsani E · Substance abuse treatment, prevention, and policy · 2023
Randomized trial68 participantsflagStress Relief forscienceZinc
- A systematic review of the association between zinc and anxiety.
Azargoonjahromi A · Nutrition reviews · 2024
Systematic review9 studies pooledflagStress Relief forscienceZinc
- Zinc acutely and temporarily inhibits adrenal cortisol secretion in humans. A preliminary report.
Brandão-Neto J; de Mendonça BB; Shuhama T; Marchini JS; Pimenta WP; Tornero MT · Biological trace element research · 1991
Clinical trial27 participantsflagStress Relief forscienceZinc
- Low Zinc, Copper, and Manganese Intake is Associated with Depression and Anxiety Symptoms in the Japanese Working Population: Findings from the Eating Habit and Well-Being Study.
Nakamura M; Miura A; Nagahata T; Shibata Y; Okada E; Ojima T · Nutrients · 2019
Cross-sectional study2,089 participantsflagStress Relief forscienceZinc
- Mediation effects of thyroid hormones in the associations between essential metal elements and anxiety or depression symptoms in the elderly.
Li J; Wang W; Peng Y; Qin N; Li J; Wei Y; Wang B; Zeng H; Li H; Cheng L · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
Observational study416 participantsflagStress Relief forscienceZinc
- Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
Randomized trial90 participantsflagTestosterone Support forscienceVitamin D
- Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
Randomized trial60 participantsflagTestosterone Support forscienceVitamin D
- Association between plasma 25-OH vitamin D and testosterone levels in men.
Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
Case-control study1,362 participantsflagTestosterone Support forscienceVitamin D
- Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
Other4,254 participantsflagTestosterone Support forscienceVitamin D
- Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
Cohort study643 participantsflagTestosterone Support forscienceVitamin D
- Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
Cross-sectional study219 participantsflagTestosterone Support forscienceZinc
- Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
Scoping reviewflagTestosterone Support forscienceZinc
- Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
Narrative reviewflagTestosterone Support forscienceZinc
- Clinical, endocrinological and biochemical effects of zinc deficiency.
Prasad AS · Clinics in endocrinology and metabolism · 1986
Narrative reviewflagTestosterone Support forscienceZinc
- Clinical, endocrinologic, and biochemical effects of zinc deficiency.
Prasad AS · Special topics in endocrinology and metabolism · 1986
Narrative reviewflagTestosterone Support forscienceZinc
- What did we learn in 35 years of research on nutrition and supplements for age-related macular degeneration: a systematic review.
Pameijer EM; Heus P; Damen JAA; Spijker R; Hooft L; Ringens PJ; Imhof SM; van Leeuwen R · Acta ophthalmologica · 2023
Systematic review27 studies pooledflagVision Support forscienceCopper
- Dietary Nutrient Intake and Progression to Late Age-Related Macular Degeneration in the Age-Related Eye Disease Studies 1 and 2.
Agrón E; Mares J; Clemons TE; Swaroop A; Chew EY; Keenan TDL; AREDS and AREDS2 Research Groups · Ophthalmology · 2021
Cohort study8,242 participantsflagVision Support forscienceCopper
- Association between late age-related macular degeneration and dietary intake of copper, iron, zinc and selenium: a 2005-2008 NHANES cross-sectional observational study.
Lu Y; Li C; Liu Y; Wu T; Lu P · BMC ophthalmology · 2025
Observational study4,996 participantsflagVision Support forscienceCopper
- Associations between dietary nutrient intake and the risk of multiple age-related ocular diseases: evidence from longitudinal analysis.
Yang Y; Zou H · The journal of nutrition, health & aging · 2026
Cohort study103,192 participantsflagVision Support forscienceCopper
- Dietary habits and dietary nutrient intake in patients with age-related macular degeneration: A case-control study.
Šalková Kráľová J; Kolář P; Kapounová Z; Veselý P; Derflerová Brázdová Z · Central European journal of public health · 2023
Case-control study151 participantsflagVision Support forscienceCopper
- Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction: A vehicle-controlled, randomized clinical trial.
Watson SL; Jones LW; Stapleton F; Hinds M; Ng A; Tan J; Alster Y; Bosworth C; Rafaeli O; DePuy V; CELESTIAL STUDY Group · The ocular surface · 2026
Randomized trial245 participantsflagVision Support forscienceSelenium
- Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction over six months of treatment: A Phase 2, vehicle-controlled, randomized extension trial.
Downie LE; Craig JP; Stapleton F; Tan J; Jones LW; Ng A; Hinds M; Bosworth C; Alster Y · The ocular surface · 2025
Randomized trial245 participantsflagVision Support forscienceSelenium
- AZR-MD-001 0.5% selenium sulfide ophthalmic ointment for the treatment of contact lens discomfort: A vehicle-controlled, randomized, clinical trial.
Stapleton F; Hinds M; Tan J; Jones L; Chalmers R; Bosworth C; Alster Y · The ocular surface · 2025
Randomized trial67 participantsflagVision Support forscienceSelenium
- The effect of a biweekly novel selenium sulfide-containing topical treatment in symptomatic contact lens wearers: An exploratory study.
Stapleton F; Jia T; DePuy V; Bosworth C; Gleeson M; Tan J · The ocular surface · 2025
Randomized trial14 participantsflagVision Support forscienceSelenium
- A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa.
Berson EL; Rosner B; Sandberg MA; Hayes KC; Nicholson BW; Weigel-DiFranco C; Willett W · Archives of ophthalmology (Chicago, Ill. : 1960) · 1993
Randomized trial601 participantsflagVision Support forscienceVitamin A
- Efficacy and safety of retinol palmitate ophthalmic solution in the treatment of dry eye: a Japanese Phase II clinical trial.
Toshida H; Funaki T; Ono K; Tabuchi N; Watanabe S; Seki T; Otake H; Kato T; Ebihara N; Murakami A · Drug design, development and therapy · 2018
Randomized trial66 participantsflagVision Support forscienceVitamin A
- Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age.
Imdad A; Mayo-Wilson E; Haykal MR; Regan A; Sidhu J; Smith A; Bhutta ZA · The Cochrane database of systematic reviews · 2022
Meta-analysis1,223,856 participants47 studies pooledflagVision Support forscienceVitamin A
- Vitamin A supplementation improves retinal function in infants at risk of retinopathy of prematurity.
Mactier H; McCulloch DL; Hamilton R; Galloway P; Bradnam MS; Young D; Lavy T; Farrell L; Weaver LT · The Journal of pediatrics · 2012
Randomized trial89 participantsflagVision Support forscienceVitamin A
- Effect of short-term, high-dose retinol on dark adaptation in aging and early age-related maculopathy.
Owsley C; McGwin G; Jackson GR; Heimburger DC; Piyathilake CJ; Klein R; White MF; Kallies K · Investigative ophthalmology & visual science · 2006
Randomized trial104 participantsflagVision Support forscienceVitamin A
- Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
Randomized trial400 participantsflagVision Support forscienceVitamin C
- Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
Observational studyflagVision Support forscienceVitamin C
- Nutritional modulation of cataract.
Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
Narrative reviewflagVision Support forscienceVitamin C
- Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
Case-control study530 participantsflagVision Support forscienceVitamin C flagVision Support forscienceVitamin E
- Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
Case-control study883 participantsflagVision Support forscienceVitamin C
- Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration.
Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2018
Meta-analysis55,614 participants4 studies pooledflagVision Support forscienceVitamin E
- Dietary carotenoids, vitamins C and E, and risk of cataract in women: a prospective study.
Christen WG; Liu S; Glynn RJ; Gaziano JM; Buring JE · Archives of ophthalmology (Chicago, Ill. : 1960) · 2008
Cohort study35,551 participantsflagVision Support forscienceVitamin E
- Long-term nutrient intake and 5-year change in nuclear lens opacities.
Jacques PF; Taylor A; Moeller S; Hankinson SE; Rogers G; Tung W; Ludovico J; Willett WC; Chylack LT · Archives of ophthalmology (Chicago, Ill. : 1960) · 2005
Cohort study408 participantsflagVision Support forscienceVitamin E
- Dietary intake of antioxidants and risk of age-related macular degeneration.
van Leeuwen R; Boekhoorn S; Vingerling JR; Witteman JC; Klaver CC; Hofman A; de Jong PT · JAMA · 2005
Cohort study4,765 participantsflagVision Support forscienceVitamin E
- Antioxidant vitamin and mineral supplements for age-related macular degeneration.
Evans JR · The Cochrane database of systematic reviews · 2002
Systematic review170 participants7 studies pooledflagVision Support forscienceZinc
- Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.
Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2023
Meta-analysis3,790 participants5 studies pooledflagVision Support forscienceZinc
- Oral zinc in macular degeneration.
Newsome DA; Swartz M; Leone NC; Elston RC; Miller E · Archives of ophthalmology (Chicago, Ill. : 1960) · 1988
Randomized trial151 participantsflagVision Support forscienceZinc
- A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
Age-Related Eye Disease Study Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2001
Randomized trial3,640 participantsflagVision Support forscienceZinc
- Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand.
Udomkesmalee E; Dhanamitta S; Sirisinha S; Charoenkiatkul S; Tuntipopipat S; Banjong O; Rojroongwasinkul N; Kramer TR; Smith JC · The American journal of clinical nutrition · 1992
Randomized trial133 participantsflagVision Support forscienceZinc