Product Image

Prenatal 1

Bayer One A Day Women's
4.5
★ ★ ★ ★ ★
(11052 ratings)
Vitamin A 4000 IU
Iodine 150 mcg
Niacin 20 mg
Biotin 300 mcg
Iron 28 mg
Copper 2 mg
Zinc 15 mg
Product Image
Score74
A convenient prenatal softgel covers folate, iron, iodine, and omega-3 basics. Missing DHA and nutrient-form details limit precision.
How scoring works
Quantity:30 Softgel(s) • (30 servings)
Goals:
General Health
Hair Health
Energy
Skin Health

Score 74

A convenient prenatal softgel covers folate, iron, iodine, and omega-3 basics. Missing DHA and nutrient-form details limit precision.
How scoring works
$12.23($0.40 per serving)
Walmart
$ 12.23
iHerb
$ 19.62
iHerb
$ 19.62
Amazon
$ 12.23
Report prices

Analysis

The softgel supplies key prenatal nutrients including 800 mcg folic acid, 28 mg iron, 150 mcg iodine, vitamin D, and omega-3 fatty acids. Beta-carotene is a pregnancy-appropriate vitamin A form in the supplied data.

Fish oil is included, but EPA and DHA are not separated, so the amount of DHA cannot be confirmed. Magnesium and calcium are partial contributions, while vitamin D, B12, iron, iodine, and zinc forms are not identified.

One-softgel dosing is convenient and may improve consistency. Prenatal needs remain individual, so the formula should be compared with diet, laboratory results, and any additional choline or DHA plan.

Who is it for
  • People preparing for or experiencing pregnancy
  • Users who want iron and fish oil in one softgel
  • Those who can review the formula with prenatal care
Best for
  • Foundational prenatal supplementation
  • One-softgel convenience
  • Combining folic acid, iron, iodine, and omega-3s

Pros

  • Provides 800 mcg folic acid
  • Includes 28 mg iron and 150 mcg iodine
  • Adds fish-derived omega-3s

Cons

  • EPA and DHA amounts are not disclosed
  • Magnesium and calcium are modest
  • Several nutrient forms are unspecified

Warnings

  • Fish oil makes the product unsuitable for people with fish allergy unless the manufacturer confirms safety.
  • The 28 mg iron amount can cause nausea or constipation and should be kept out of children's reach.
  • Thyroid conditions or thyroid medicine use warrant individualized iodine planning during pregnancy.

Nutrient quality

74 High impact

Folic acid, iron, iodine, and beta-carotene provide a coherent prenatal base. Missing forms, low vitamin D and minerals, and unquantified DHA limit nutrient quality.

Ingredient transparency

68 High impact

Active totals are mostly disclosed, but chemical forms and separate EPA and DHA amounts are missing. Daily directions and a complete excipient list are not supplied.

Customer satisfaction

72 High impact

The supplied aggregate satisfaction metric is supported by the available feedback volume. No feedback excerpts or complaint themes are supplied, so specific experience patterns cannot be verified.

Value for money

81 Highest impact

Core nutrient breadth supports favorable serving value. The formula largely avoids costly low-value extras.

Report analysis

Goals

General Health
General Health
Impact
Highest effect
A Goal FitB Strength of SupportA- CoverageA Formula Quality
Folate · 800 mcgVitamin B12 · 8 mcgVitamin D · 400 IUMagnesium · 50 mgZinc · 15 mgVitamin C · 60 mg

A broad prenatal nutrient base combines folate, iron, iodine, vitamin D, and fish-derived omega-3s in a convenient serving. The omega-3 contribution lacks EPA and DHA detail, several vitamin forms are unspecified, and magnesium is modest.

Coverage spans common nutrient gaps, blood formation, bone support, and essential fatty acids. The prenatal combination is cohesive and avoids unrelated botanical padding.

Study evidence
Folate Supportive 80 studies
Magnesium Supportive 114 studies
Vitamin D Supportive 115 studies
Hair Health
Hair Health
Impact
Highest effect
A- Goal FitB Strength of SupportB+ CoverageB+ Formula Quality
Biotin · 300 mcgVitamin D · 400 IUZinc · 15 mgIron · 28 mgVitamin C · 60 mg

Iron, zinc, biotin, folate, iodine, vitamin C, and omega-3 fatty acids provide broad support for pregnancy-related nutritional needs that can influence hair shedding. The iron amount is especially relevant when low ferritin contributes to hair loss.

The key amounts are meaningful and the oil-based softgel suits fat-soluble nutrients, but iron, zinc, and vitamin forms are not identified. Fish oil makes the product unsuitable for people with fish allergy, and the prenatal iron amount should be used for its intended pregnancy context or demonstrated need.

Study evidence
Biotin Supportive 4 studies
Folate Mixed 15 studies
Iodine No effect 1 study
Iron Disputed 25 studies
Omega-3 Adverse 4 studies
Vitamin C Mixed 5 studies
Zinc Supportive 22 studies
Energy
Energy
Impact
High effect
B+ Goal FitC Strength of SupportB CoverageB+ Formula Quality
Iodine · 150 mcgVitamin D · 400 IUVitamin B5 · 10 mgMagnesium · 50 mgRiboflavin · 2 mgThiamin · 1.7 mgVitamin B12 · 8 mcgIron · 28 mg

A substantial iron amount can support energy when low iron limits oxygen delivery, while iodine and B vitamins add basic metabolic support. The softgel also includes omega-3 fatty acids.

Most chemical forms are not disclosed, and vitamin D, vitamin B12, and magnesium are below goal-focused amounts. The prenatal design is best matched to pregnancy needs rather than used as a general energy supplement.

Study evidence
Iodine Adverse 3 studies
Iron Supportive 74 studies
Magnesium Supportive 4 studies
Vitamin D Supportive 32 studies
Skin Health
Skin Health
Impact
High effect
B Goal FitC Strength of SupportB- CoverageC+ Formula Quality
Zinc · 15 mgVitamin C · 60 mgCopper · 2 mgVitamin E · 30 IUOmega-3 · 235 mg

Vitamin A, zinc, copper, vitamin C, vitamin E, biotin, and omega-3s support turnover, repair, and barrier function. The nutrients have established skin roles, though the prenatal formula is not clinically targeted to skin outcomes.

Zinc and copper are useful, while vitamin C and omega-3 amounts are modest for focused skin support. Softgel delivery suits fat-soluble nutrients, but omega-3 composition and several mineral forms are not specified.

Study evidence
Biotin Supportive 10 studies
Copper Supportive 16 studies
Omega-3 Supportive 35 studies
Vitamin A Supportive 106 studies
Vitamin C Supportive 53 studies
Vitamin E Supportive 38 studies
Zinc Supportive 66 studies
Immunity
Immunity
Impact
Moderate effect
C+ Goal FitD Strength of SupportC+ CoverageB Formula Quality
Magnesium · 50 mgVitamin C · 60 mgZinc · 15 mgVitamin A · 4000 IUVitamin D · 400 IUOmega-3 · 235 mg

Vitamin A, vitamin C, vitamin D, zinc, and copper provide broad foundational support for immune function during pregnancy. The oil-based softgel may support absorption of the fat-soluble vitamins.

Most immune nutrients remain at maintenance amounts, and the label does not identify the forms of vitamin D or zinc. The high iron amount suits prenatal use but makes the formula inappropriate as a general immunity supplement for people who do not need extra iron.

Study evidence
Iron Supportive 23 studies
Omega-3 Supportive 24 studies
Vitamin A Supportive 107 studies
Vitamin C Supportive 53 studies
Vitamin D Supportive 85 studies
Zinc Supportive 73 studies
Nail Health
Nail Health
Impact
Moderate effect
C- Goal FitC- Strength of SupportC+ CoverageB- Formula Quality
Biotin · 300 mcg

Biotin, zinc, iron, vitamin C, and omega-3 fats provide broad nutritional support for nail growth during pregnancy. The formula may be especially relevant when iron or zinc intake is inadequate, but it does not supply direct structural proteins or silicon.

Useful amounts of biotin, zinc, and iron are disclosed in a compact one-softgel serving. Unspecified mineral and vitamin forms reduce quality confidence, and the prenatal purpose should remain the main reason for use.

Study evidence
Biotin Supportive 8 studies
Iron Disputed 4 studies
Vitamin C Supportive 1 study
Zinc No effect 1 study

Ingredients

IngredientAmount per serving
Calories
10 Calorie(s)
Total Fat
0.5 Gram(s)
Cholesterol
25 mg
Vitamin A (Beta-Carotene)
 4000 IU
Vitamin C
60 mg
Vitamin D
400 IU
Vitamin E
30 IU
Thiamine (Vitamin B1)
 1.7 mg
Riboflavin (Vitamin B2)
 2 mg
Niacin
20 mg
Vitamin B6
2.5 mg
Folic Acid
800 mcg
Vitamin B12
8 mcg
Biotin
300 mcg
Pantothenic Acid
10 mg
Calcium
200 mg
Iron
28 mg
Iodine
150 mcg
Magnesium
50 mg
Zinc
15 mg
Copper
2 mg
Sodium
15 mg
Omega-3 Fatty Acids (Fish Oil)
 235 mg
Pregnant Women 18–50
Report overview
Vitamin A (Beta-Carotene) · 4000 IU OverallScore82
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value

Beta-carotene avoids preformed vitamin A, though the label does not identify a natural source. The softgel and included fish oil support absorption, while the amount fits the preferred range for a multivitamin. Standardized value is good after accounting for the broader prenatal nutrient profile.

View ingredientView products
Iodine · 150 mcg OverallScore72
D- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

The listed iodine amount is appropriate for daily support, but the chemical form or source is not disclosed. A one-softgel serving is convenient and remains within the established upper limit. The cost per serving is moderate, while the prenatal formula adds nutrients beyond iodine.

View ingredientView products
Niacin · 20 mg OverallScore60
C+ Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyC Value

The prenatal provides an appropriate routine niacin amount within a broad nutrient formula. Its softgel is convenient, but the undisclosed niacin form prevents a confident assessment of targeted suitability or flush potential. The broader prenatal and omega-3 profile supports fair value despite weak niacin-specific transparency.

View ingredientView products
Loading alternative details
88 Performance

Prenatal

Fairhaven Health
<p>Methylfolate, methylcobalamin, vitamin D3, iodine, iron, zinc, and copper form a clearly disclosed prenatal base. Iron may cause digestive effects, but the nutrient forms and prenatal purpose are easier to assess than in the original.</p>
80 Performance

Daily Vits

NOW
<p>Iron bisglycinate, zinc bisglycinate, methylcobalamin, selenomethionine, and chelated copper and manganese improve several nutrient forms. It is not a prenatal formula and uses folic acid plus vitamin D2, so it cannot replace pregnancy-specific review.</p>
55 Performance

Enzyme Nutrition Multi-Vitamin Two Daily

Enzymedica
<p>Natural mixed vitamin E, vitamin D3, beta-carotene, and broad vitamins provide some form improvements over the original. Unquantified enzymes, probiotics, ATP, and botanicals weaken transparency, while iron and iodine are too low for a direct prenatal replacement.</p>
78 Budget

Prenatal Multivitamin/Multimineral with Folate

Spring Valley
<p>Folate, iron, iodine, zinc, vitamin D3, and other essentials provide prenatal dose coverage at a much lower serving cost. Most forms are unspecified or basic, and the high iron amount may cause nausea or constipation.</p>
77 Budget

One Daily Women's

Equate
<p>Practical amounts of folate, iron, iodine, zinc, calcium, and broad vitamins provide far less costly daily coverage. It is not specifically prenatal and most forms are undisclosed, so pregnancy suitability should not be assumed from the women's label alone.</p>
80 Budget

One Daily Women's

21st Century
<p>Iron, iodine, folate, vitamin D3, calcium, and broad vitamins offer economical coverage with clearly stated amounts. Basic mineral forms and the absence of omega-3s make it less complete for prenatal use than the original.</p>
77 Value

One Daily Women's Health

Equate
<p>Broad vitamins, folic acid, iron, iodine, zinc, copper, and calcium provide strong serving efficiency. It lacks omega-3s and does not identify most forms, so it is better viewed as a general women's multi than a complete prenatal alternative.</p>
78 Value

Hair Skin & Nails

Nature Made
<p>Beta-carotene, vitamin C, biotin, zinc, and copper offer inexpensive support for the original's skin, hair, and nail goals. It omits essential prenatal nutrients such as folate, iron, and iodine, while high biotin can interfere with laboratory tests.</p>
54 Value

FertilAid for Women

Fairhaven Health
<p>Methylfolate, active B6, methylcobalamin, iron bisglycinate, iodine, and selenomethionine provide stronger forms for preconception support. Its higher serving cost, magnesium oxide, and large hidden fertility blend weaken value compared with the original.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  2. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  3. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  4. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  5. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  6. The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
    Ju Y; Xiong W; Pang Y; Chen Z; Hou J; Zheng S; Li Z; Liu T; Xia H; Xia M; Zhong Y; Li J; Jiang X · Biological trace element research · 2026
    Scoping review18 studies pooledBone Health forCopper
  7. Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
    Chen M; Jia L; Gao R · Frontiers in nutrition · 2024
    Cohort study5,286 participantsBone Health forCopper
  8. Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
    Hu M; Wang Z; Li C; Zheng Y; Hu J · Medicine · 2025
    Cross-sectional studyBone Health forCopper
  9. The association between dietary mineral intake and bone mineral density: a cross-sectional study.
    Wei M; Wei J; Huang S · Journal of health, population, and nutrition · 2025
    Cross-sectional study11,520 participantsBone Health forCopper
  10. Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
    Cui A; Yan J; Li H; Fan Z; Wei X; Wang H; Zhuang Y · PloS one · 2024
    Cross-sectional study6,965 participantsBone Health forCopper
  11. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  12. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  13. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  14. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  15. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  16. Habitual use of fish oil supplements, genetic predisposition, and risk of fractures: a large population-based study.
    Mei Z; Chen GC; Hu J; Lin C; Sun Z; Liu C; Geng X; Yuan C; Qi Q; Zheng Y · The American journal of clinical nutrition · 2021
    Cohort study492,713 participantsBone Health forOmega-3
  17. Perilla seed oil improves bone health by inhibiting bone resorption in healthy Japanese adults: A 12-month, randomized, double-blind, placebo-controlled trial.
    Matsuzaki K; Hossain S; Wakatsuki H; Tanabe Y; Ohno M; Kato S; Shido O; Hashimoto M · Phytotherapy research : PTR · 2023
    Randomized trial52 participantsBone Health forOmega-3
  18. An increase in dietary n-3 fatty acids decreases a marker of bone resorption in humans.
    Griel AE; Kris-Etherton PM; Hilpert KF; Zhao G; West SG; Corwin RL · Nutrition journal · 2007
    Randomized trial23 participantsBone Health forOmega-3
  19. The Relationship Between Omega-3, Omega-6 and Total Polyunsaturated Fat and Musculoskeletal Health and Functional Status in Adults: A Systematic Review and Meta-analysis of RCTs.
    Abdelhamid A; Hooper L; Sivakaran R; Hayhoe RPG; Welch A; PUFAH Group · Calcified tissue international · 2020
    Meta-analysis7,288 participants28 studies pooledBone Health forOmega-3
  20. Dietary intake of fish, n-3 polyunsaturated fatty acids and risk of hip fracture: A systematic review and meta-analysis on observational studies.
    Sadeghi O; Djafarian K; Ghorabi S; Khodadost M; Nasiri M; Shab-Bidar S · Critical reviews in food science and nutrition · 2019
    Meta-analysis292,657 participants10 studies pooledBone Health forOmega-3
  21. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  22. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  23. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  24. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  25. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  26. Increased incidence of fractures in middle-aged and elderly men with low intakes of phosphorus and zinc.
    Elmståhl S; Gullberg B; Janzon L; Johnell O; Elmståhl B · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 1999
    Cohort study6,576 participantsBone Health forZinc
  27. Zinc Supplementation Increases Procollagen Type 1 Amino-Terminal Propeptide in Premenarcheal Girls: A Randomized Controlled Trial.
    Berger PK; Pollock NK; Laing EM; Chertin V; Bernard PJ; Grider A; Shapses SA; Ding KH; Isales CM; Lewis RD · The Journal of nutrition · 2016
    Randomized trial147 participantsBone Health forZinc
  28. Randomized controlled trial of prenatal zinc supplementation and fetal bone growth.
    Merialdi M; Caulfield LE; Zavaleta N; Figueroa A; Costigan KA; Dominici F; Dipietro JA · The American journal of clinical nutrition · 2004
    Randomized trial242 participantsBone Health forZinc
  29. The effects of zinc supplementation on serum zinc, alkaline phosphatase activity and fracture healing of bones.
    Sadighi A; Roshan MM; Moradi A; Ostadrahimi A · Saudi medical journal · 2009
    Randomized trial60 participantsBone Health forZinc
  30. Is Zinc an Important Trace Element on Bone-Related Diseases and Complications? A Meta-analysis and Systematic Review from Serum Level, Dietary Intake, and Supplementation Aspects.
    Ceylan MN; Akdas S; Yazihan N · Biological trace element research · 2021
    Meta-analysis40 studies pooledBone Health forZinc
  31. Association of radioactive iodine treatment with survivorship symptoms and primary care utilisation in women of reproductive age with thyroid cancer: a retrospective cohort study.
    Devanarayan P; Hartman M; Partin M · Family medicine and community health · 2026
    Cohort study10,882 participantsEnergy forIodine
  32. Energy level and fatigue after surgery for thyroid cancer: A population-based study of patient-reported outcomes.
    Hughes DT; Reyes-Gastelum D; Kovatch KJ; Hamilton AS; Ward KC; Haymart MR · Surgery · 2020
    Cohort study2,584 participantsEnergy forIodine
  33. Health-Related Quality of Life in Differentiated Thyroid Cancer Survivors: A Cross-Sectional Study From Turkey.
    Gültekin A; Kahraman MY; Şengöz T; Şimşek FS · Head & neck · 2026
    Cross-sectional study202 participantsEnergy forIodine
  34. Large-dose intravenous ferric carboxymaltose injection for iron deficiency anemia in heavy uterine bleeding: a randomized, controlled trial.
    Van Wyck DB; Mangione A; Morrison J; Hadley PE; Jehle JA; Goodnough LT · Transfusion · 2010
    Randomized trial477 participantsEnergy forIron
  35. The Effect of Parenteral or Oral Iron Supplementation on Fatigue, Sleep, Quality of Life and Restless Legs Syndrome in Iron-Deficient Blood Donors: A Secondary Analysis of the IronWoMan RCT.
    Macher S; Herster C; Holter M; Moritz M; Matzhold EM; Stojakovic T; Pieber TR; Schlenke P; Drexler C; Amrein K · Nutrients · 2021
    Randomized trial176 participantsEnergy forIron
  36. Ferric carboxymaltose vs. oral iron in the treatment of pregnant women with iron deficiency anemia: an international, open-label, randomized controlled trial (FER-ASAP).
    Breymann C; Milman N; Mezzacasa A; Bernard R; Dudenhausen J; FER-ASAP investigators · Journal of perinatal medicine · 2018
    Randomized trial252 participantsEnergy forIron
  37. Effect of iron therapy on fatigue symptoms in non-anaemic iron deficient women of reproductive age- A Randomized Controlled Trial.
    Sultana N; Bajwa FA; Sikandar MZ; Haider MM; Majeed T · JPMA. The Journal of the Pakistan Medical Association · 2026
    Randomized trial164 participantsEnergy forIron
  38. Intravenous iron isomaltoside treatment of women suffering from severe fatigue after postpartum hemorrhage.
    Holm C; Thomsen LL; Langhoff-Roos J · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019
    Randomized trial85 participantsEnergy forIron
  39. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  40. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  41. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  42. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  43. Effect of Vitamin D Supplementation on Fatigue in Multiple Sclerosis: A Systematic Review and Meta-Analysis.
    López-Muñoz P; Torres-Costoso AI; Fernández-Rodríguez R; Guzmán-Pavón MJ; de Arenas-Arroyo SN; Basco-López JÁ; Reina-Gutiérrez S · Nutrients · 2023
    Meta-analysis345 participants5 studies pooledEnergy forVitamin D
  44. Vitamin D Supplementation in Adolescents and Young Adults With Juvenile Systemic Lupus Erythematosus for Improvement in Disease Activity and Fatigue Scores: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Lima GL; Paupitz J; Aikawa NE; Takayama L; Bonfa E; Pereira RM · Arthritis care & research · 2016
    Randomized trial40 participantsEnergy forVitamin D
  45. Vitamin D in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After COVID-19 or Vaccination: A Randomized Controlled Trial.
    Kodama S; Nakata M; Konishi N; Yoshino M; Fujisawa A; Naganuma M; Kobayashi Y; Hirai Y; Kitagawa A; Miyokawa M; Mishima R; Teramukai S; Fukushima M · Nutrients · 2026
    Randomized trial91 participantsEnergy forVitamin D
  46. The effects of vitamin D supplementation on disease activity and fatigue in Libyan rheumatoid arthritis patients.
    Elfituri S · Reumatologia · 2024
    Randomized trial68 participantsEnergy forVitamin D
  47. The effect of home-based aerobic training and vitamin D supplementation on fatigue and quality of life in patients with multiple sclerosis during COVID-19 outbreak.
    Bahmani E; Hoseini R; Amiri E · Science & sports · 2022
    Randomized trial40 participantsEnergy forVitamin D
  48. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsGeneral Health forFolate
  49. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsGeneral Health forFolate
  50. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsGeneral Health forFolate
  51. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewGeneral Health forFolate
  52. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledGeneral Health forFolate
  53. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  54. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  55. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  56. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
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  69. Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
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  76. Assessment of Serum Ferritin Levels in Female Patients With Telogen Effluvium.
    Thamotharan N; Harikumar MV; Sundaram M; Swaminathan A; Rangarajan S · Cureus · 2026
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  77. Diagnosis and treatment of female alopecia: Focusing on the iron deficiency-related alopecia.
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  78. Bioengineered Plants Can Be a Useful Source of Omega-3 Fatty Acids.
    Amjad Khan W; Chun-Mei H; Khan N; Iqbal A; Lyu SW; Shah F · BioMed research international · 2017
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    Caroline Le Floc'h, Ahsène Cheniti, Sophie Connétable, Nathalie Piccardi, Colombina Vincenzi, Antonella Tosti · Journal of cosmetic dermatology · 2015
    Randomized trial120 participantsHair Health forOmega-3
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    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
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  85. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
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    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
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    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
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  91. The immune response in iron-deficient children: Impaired cellular defense mechanisms with altered humoral components.
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    Mu Q; Chen L; Gao X; Shen S; Sheng W; Min J; Wang F · Science bulletin · 2023
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    Ganz T · Current topics in microbiology and immunology · 2006
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    Preston AE; Drakesmith H; Frost JN · Immunotherapy advances · 2025
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    Barber MF; Elde NC · Trends in genetics : TIG · 2016
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    Liu T; Wang X; Wang XH; Wang C; Cai JZ; Wang HF · Intensive & critical care nursing · 2025
    Meta-analysis3,152 participants41 studies pooledImmunity forOmega-3
  97. Effect of ω-3 polyunsaturated fatty acid-supplemented parenteral nutrition on inflammatory and immune function in postoperative patients with gastrointestinal malignancy: A meta-analysis of randomized control trials in China.
    Zhao Y; Wang C · Medicine · 2018
    Meta-analysis1,008 participants16 studies pooledImmunity forOmega-3
  98. Effects of omega-3 fatty acids on patients undergoing surgery for gastrointestinal malignancy: a systematic review and meta-analysis.
    Yu J; Liu L; Zhang Y; Wei J; Yang F · BMC cancer · 2017
    Meta-analysis623 participants9 studies pooledImmunity forOmega-3
  99. Omega-3 PUFA supplementation and the response to evoked endotoxemia in healthy volunteers.
    Ferguson JF; Mulvey CK; Patel PN; Shah RY; Doveikis J; Zhang W; Tabita-Martinez J; Terembula K; Eiden M; Koulman A; Griffin JL; Mehta NN; Shah R; Propert KJ; Song WL; Reilly MP · Molecular nutrition & food research · 2015
    Randomized trial60 participantsImmunity forOmega-3
  100. Omega-3 fatty acid supplementation during pregnancy and respiratory symptoms in children.
    Escamilla-Nuñez MC; Barraza-Villarreal A; Hernández-Cadena L; Navarro-Olivos E; Sly PD; Romieu I · Chest · 2014
    Randomized trial1,094 participantsImmunity forOmega-3
  101. Depressed immune response to tetanus in children with vitamin A deficiency.
    Semba RD; Muhilal; Scott AL; Natadisastra G; Wirasasmita S; Mele L; Ridwan E; West KP; Sommer A · The Journal of nutrition · 1992
    Randomized trial236 participantsImmunity forVitamin A
  102. Impact of a single megadose of vitamin A at delivery on breastmilk of mothers and morbidity of their infants.
    Roy SK; Islam A; Molla A; Akramuzzaman SM; Jahan F; Fuchs G · European journal of clinical nutrition · 1997
    Randomized trial50 participantsImmunity forVitamin A
  103. Vitamin A supplementation reduces measles morbidity in young African children: a randomized, placebo-controlled, double-blind trial.
    Coutsoudis A; Broughton M; Coovadia HM · The American journal of clinical nutrition · 1991
    Randomized trial60 participantsImmunity forVitamin A
  104. Vitamin A supplementation enhances specific IgG antibody levels and total lymphocyte numbers while improving morbidity in measles.
    Coutsoudis A; Kiepiela P; Coovadia HM; Broughton M · The Pediatric infectious disease journal · 1992
    Randomized trial60 participantsImmunity forVitamin A
  105. Vitamin A supplementation reduces the monocyte chemoattractant protein-1 intestinal immune response of Mexican children.
    Long KZ; Santos JI; Estrada Garcia T; Haas M; Firestone M; Bhagwat J; Dupont HL; Hertzmark E; Rosado JL; Nanthakumar NN · The Journal of nutrition · 2006
    Randomized trial127 participantsImmunity forVitamin A
  106. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  107. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  108. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  109. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  110. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  111. Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
    Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
    Meta-analysis11,321 participants25 studies pooledImmunity forVitamin D
  112. Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
    Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
    Meta-analysis4,859 participants10 studies pooledImmunity forVitamin D
  113. Vitamin D3 and deconvoluting a rash.
    Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
    Randomized trial28 participantsImmunity forVitamin D
  114. Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
    Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
    Randomized trial110 participantsImmunity forVitamin D
  115. Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
    Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
    Meta-analysis50,554 participants65 studies pooledImmunity forVitamin D
  116. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  117. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  118. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  119. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  120. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  121. Biotin for the treatment of nail disease: what is the evidence?
    Lipner SR; Scher RK · The Journal of dermatological treatment · 2018
    Narrative reviewNail Health forBiotin
  122. Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy.
    Colombo VE; Gerber F; Bronhofer M; Floersheim GL · Journal of the American Academy of Dermatology · 1991
    Other32 participantsNail Health forBiotin
  123. Treatment of brittle nail with a hydroxypropyl chitosan-based lacquer, alone or in combination with oral biotin: A randomized, assessor-blinded trial.
    Chiavetta A; Mazzurco S; Secolo MP; Tomarchio G; Milani M · Dermatologic therapy · 2020
    Randomized trial50 participantsNail Health forBiotin
  124. Vitamins and minerals: their role in nail health and disease.
    Scheinfeld N; Dahdah MJ; Scher R · Journal of drugs in dermatology : JDD · 2007
    Narrative reviewNail Health forBiotin Nail Health forIron Nail Health forZinc
  125. A pilot iron substitution programme in female blood donors with iron deficiency without anaemia.
    Pittori C; Buser A; Gasser UE; Sigle J; Job S; Rüesch M; Tichelli A; Infanti L · Vox sanguinis · 2011
    Non-randomized trial224 participantsNail Health forIron
  126. Evaluation of nail abnormalities.
    Tully AS; Trayes KP; Studdiford JS · American family physician · 2013
    Narrative reviewNail Health forIron
  127. Efficacy and tolerability of a biomineral formulation for treatment of onychoschizia: a randomized trial
    Adele Sparavigna, Beatrice Tenconi, Laura La Penna · Clinical, Cosmetic and Investigational Dermatology · 2019
    Randomized trial48 participantsNail Health forIron
  128. Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient.
    Dunleavy KA; Ungaro RC; Manning L; Gold S; Novak J; Colombel JF · Crohn's & colitis 360 · 2023
    Other20 participantsNail Health forVitamin C
  129. Effects of daily iron supplementation in primary-school-aged children: systematic review and meta-analysis of randomized controlled trials.
    Low M; Farrell A; Biggs BA; Pasricha SR · CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2014
    Meta-analysis7,089 participants32 studies pooledProductivity Boost forIron
  130. Consumption of Iron-Biofortified Beans Positively Affects Cognitive Performance in 18- to 27-Year-Old Rwandan Female College Students in an 18-Week Randomized Controlled Efficacy Trial.
    Murray-Kolb LE; Wenger MJ; Scott SP; Rhoten SE; Lung'aho MG; Haas JD · The Journal of nutrition · 2017
    Randomized trial150 participantsProductivity Boost forIron
  131. Functional consequences of iron supplementation in iron-deficient female cotton mill workers in Beijing, China.
    Li R; Chen X; Yan H; Deurenberg P; Garby L; Hautvast JG · The American journal of clinical nutrition · 1994
    Randomized trial80 participantsProductivity Boost forIron
  132. The Effect of Iron-Fortified Lentils on Blood and Cognitive Status among Adolescent Girls in Bangladesh.
    Barnett AL; Wenger MJ; Yunus FM; Jalal C; DellaValle DM · Nutrients · 2023
    Randomized trial359 participantsProductivity Boost forIron
  133. Daily iron supplementation for improving anaemia, iron status and health in menstruating women.
    Low MS; Speedy J; Styles CE; De-Regil LM; Pasricha SR · The Cochrane database of systematic reviews · 2016
    Meta-analysis8,506 participants67 studies pooledProductivity Boost forIron
  134. Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters.
    Aksac SE; Bilgili SG; Yavuz GO; Yavuz IH; Aksac M; Karadag AS · International journal of dermatology · 2021
    Non-randomized trial60 participantsSkin Health forBiotin
  135. Generalized seborrhoeic dermatitis. Clinical and therapeutic data of 25 patients.
    Messaritakis J; Kattamis C; Karabula C; Matsaniotis N · Archives of disease in childhood · 1976
    Non-randomized trial25 participantsSkin Health forBiotin
  136. Holocarboxylase synthetase deficiency: novel clinical and molecular findings.
    Tammachote R; Janklat S; Tongkobpetch S; Suphapeetiporn K; Shotelersuk V · Clinical genetics · 2010
    Case series4 participantsSkin Health forBiotin
  137. Noninferiority of Copper Dressings Than Negative Pressure Wound Therapy in Healing Diabetic Wounds: A Randomized Clinical Trial.
    Melamed E; Dabbah J; Israel T; Kan I; Pinzur MS; Roth T; Borkow G · Advances in wound care · 2026
    Randomized trialSkin Health forCopper
  138. Improvement of facial skin characteristics using copper oxide containing pillowcases: a double-blind, placebo-controlled, parallel, randomized study.
    Borkow G; Gabbay J; Lyakhovitsky A; Huszar M · International journal of cosmetic science · 2010
    Randomized trial57 participantsSkin Health forCopper
  139. Radially Electrospun Fibrous Membrane Incorporated with Copper Peroxide Nanodots Capable of Self-Catalyzed Chemodynamic Therapy for Angiogenesis and Healing Acceleration of Diabetic Wounds.
    Huang Y; Qi L; Liu Z; Jiang Y; Wang J; Liu L; Li Y; Zhang L; Feng G · ACS applied materials & interfaces · 2023
    Animal experimentSkin Health forCopper
  140. Engineering copper nanoparticle/polysaccharide-immobilized cotton gauze for accelerated healing of Staphylococcus aureus-infected dermal wounds.
    Sahoo M; Banerjee T; Virkar S; Das S; Biswas S; Mitra D · Journal of materials chemistry. B · 2026
    Animal experimentSkin Health forCopper
  141. Stimulation of Healing of Non-Infected Stagnated Diabetic Wounds by Copper Oxide-Impregnated Wound Dressings.
    Melamed E; Rovitsky A; Roth T; Assa L; Borkow G · Medicina (Kaunas, Lithuania) · 2021
    Single-arm trialSkin Health forCopper
  142. Dietetic intervention in psoriatic arthritis: the DIETA trial.
    Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
    Randomized trial97 participantsSkin Health forOmega-3
  143. Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
    Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
    Randomized trial49 participantsSkin Health forOmega-3
  144. Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
    Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
    Randomized trial60 participantsSkin Health forOmega-3
  145. Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
    Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
    Randomized trial50 participantsSkin Health forOmega-3
  146. Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
    Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
    Randomized trial42 participantsSkin Health forOmega-3
  147. Efficacy and Tolerability of Topical 0.1% Stabilized Bioactive Retinol for Photoaging: A Vehicle-Controlled Integrated Analysis.
    Farris P; Berson D; Bhatia N; Goldberg D; Lain E; Mariwalla K; Zeichner J; Miller D; McGuire T; Kizoulis M · Journal of drugs in dermatology : JDD · 2024
    Meta-analysis471 participants6 studies pooledSkin Health forVitamin A
  148. Tensile properties and contours of aging facial skin. A controlled double-blind comparative study of the effects of retinol, melibiose-lactose and their association.
    Piérard-Franchimont C; Castelli D; Cromphaut IV; Bertin C; Ries G; Cauwenbergh G; Piérard GE · Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2016
    Randomized trial120 participantsSkin Health forVitamin A
  149. Antiaging action of retinol: from molecular to clinical.
    Bellemère G; Stamatas GN; Bruère V; Bertin C; Issachar N; Oddos T · Skin pharmacology and physiology · 2009
    Randomized trial48 participantsSkin Health forVitamin A
  150. An Updated Review of Topical Tretinoin in Dermatology: From Acne and Photoaging to Skin Cancer.
    Balado-Simó P; Morgado-Carrasco D; Gómez-Armayones S; López-Ferrer A; Barco D; Ferrándiz-Pulido C; Podlipnik S · Journal of clinical medicine · 2025
    Narrative reviewSkin Health forVitamin A
  151. Novel Cyclized Hexapeptide-9 Outperforms Retinol Against Skin Aging: A Randomized, Double-Blinded, Active- and Vehicle-Controlled Clinical Trial.
    Chang H; Tao K; Yang Y; Wang Y; Ge M; Wang X; Tang S; Yu H · Journal of cosmetic dermatology · 2025
    Randomized trialSkin Health forVitamin A
  152. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  153. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  154. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  155. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  156. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  157. Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis.
    Javanbakht MH; Keshavarz SA; Djalali M; Siassi F; Eshraghian MR; Firooz A; Seirafi H; Ehsani AH; Chamari M; Mirshafiey A · The Journal of dermatological treatment · 2011
    Randomized trial45 participantsSkin Health forVitamin E
  158. Serum vitamin E levels and chronic inflammatory skin diseases: A systematic review and meta-analysis.
    Liu X; Yang G; Luo M; Lan Q; Shi X; Deng H; Wang N; Xu X; Zhang C · PloS one · 2022
    Meta-analysis20 studies pooledSkin Health forVitamin E
  159. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forVitamin E Skin Health forZinc
  160. Effects of tocotrienol on aging skin: A systematic review.
    Ghazali NI; Mohd Rais RZ; Makpol S; Chin KY; Yap WN; Goon JA · Frontiers in pharmacology · 2022
    Systematic reviewSkin Health forVitamin E
  161. Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans.
    Stahl W; Heinrich U; Jungmann H; Sies H; Tronnier H · The American journal of clinical nutrition · 2000
    Randomized trialSkin Health forVitamin E
  162. Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
    Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
    Meta-analysis2,088 participants20 studies pooledSkin Health forZinc
  163. Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
    Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
    Cohort study23 participantsSkin Health forZinc
  164. Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
    Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
    Randomized trial30 participantsSkin Health forZinc
  165. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
    Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
    Randomized trial90 participantsSkin Health forZinc
  166. What did we learn in 35 years of research on nutrition and supplements for age-related macular degeneration: a systematic review.
    Pameijer EM; Heus P; Damen JAA; Spijker R; Hooft L; Ringens PJ; Imhof SM; van Leeuwen R · Acta ophthalmologica · 2023
    Systematic review27 studies pooledVision Support forCopper
  167. Dietary Nutrient Intake and Progression to Late Age-Related Macular Degeneration in the Age-Related Eye Disease Studies 1 and 2.
    Agrón E; Mares J; Clemons TE; Swaroop A; Chew EY; Keenan TDL; AREDS and AREDS2 Research Groups · Ophthalmology · 2021
    Cohort study8,242 participantsVision Support forCopper
  168. Association between late age-related macular degeneration and dietary intake of copper, iron, zinc and selenium: a 2005-2008 NHANES cross-sectional observational study.
    Lu Y; Li C; Liu Y; Wu T; Lu P · BMC ophthalmology · 2025
    Observational study4,996 participantsVision Support forCopper
  169. Associations between dietary nutrient intake and the risk of multiple age-related ocular diseases: evidence from longitudinal analysis.
    Yang Y; Zou H · The journal of nutrition, health & aging · 2026
    Cohort study103,192 participantsVision Support forCopper
  170. Dietary habits and dietary nutrient intake in patients with age-related macular degeneration: A case-control study.
    Šalková Kráľová J; Kolář P; Kapounová Z; Veselý P; Derflerová Brázdová Z · Central European journal of public health · 2023
    Case-control study151 participantsVision Support forCopper
  171. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  172. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  173. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  174. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C Vision Support forVitamin E
  175. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C
  176. Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2018
    Meta-analysis55,614 participants4 studies pooledVision Support forVitamin E
  177. Dietary carotenoids, vitamins C and E, and risk of cataract in women: a prospective study.
    Christen WG; Liu S; Glynn RJ; Gaziano JM; Buring JE · Archives of ophthalmology (Chicago, Ill. : 1960) · 2008
    Cohort study35,551 participantsVision Support forVitamin E
  178. Long-term nutrient intake and 5-year change in nuclear lens opacities.
    Jacques PF; Taylor A; Moeller S; Hankinson SE; Rogers G; Tung W; Ludovico J; Willett WC; Chylack LT · Archives of ophthalmology (Chicago, Ill. : 1960) · 2005
    Cohort study408 participantsVision Support forVitamin E
  179. Dietary intake of antioxidants and risk of age-related macular degeneration.
    van Leeuwen R; Boekhoorn S; Vingerling JR; Witteman JC; Klaver CC; Hofman A; de Jong PT · JAMA · 2005
    Cohort study4,765 participantsVision Support forVitamin E
  180. Antioxidant vitamin and mineral supplements for age-related macular degeneration.
    Evans JR · The Cochrane database of systematic reviews · 2002
    Systematic review170 participants7 studies pooledVision Support forZinc
  181. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2023
    Meta-analysis3,790 participants5 studies pooledVision Support forZinc
  182. Oral zinc in macular degeneration.
    Newsome DA; Swartz M; Leone NC; Elston RC; Miller E · Archives of ophthalmology (Chicago, Ill. : 1960) · 1988
    Randomized trial151 participantsVision Support forZinc
  183. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
    Age-Related Eye Disease Study Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2001
    Randomized trial3,640 participantsVision Support forZinc
  184. Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand.
    Udomkesmalee E; Dhanamitta S; Sirisinha S; Charoenkiatkul S; Tuntipopipat S; Banjong O; Rojroongwasinkul N; Kramer TR; Smith JC · The American journal of clinical nutrition · 1992
    Randomized trial133 participantsVision Support forZinc