Thyroid Complex

Thyroid Complex

The Vitamin Shoppe4.8 (85 ratings)
Format:Capsule Quantity: 100 Capsule(s) · 100 servings
Goals
$13.99 $0.13 per serving

Product analysis

57 out of 100

Thyroid Complex supplies nutrients involved in normal thyroid function and energy use, with the clearest relevance when intake is low. An incompletely described organ blend makes the full formula harder to assess.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality48

The named nutrient forms vary in how well their quality is established. Several remain uncertain, and the organ blend cannot be assessed fully without its proportions.

Ingredient Transparency78

All listed amounts and nearly all forms are disclosed. The iodine-source proportions and organ-blend composition remain unclear, limiting a complete comparison.

Value For Money56

Several nutrient price comparisons are favorable, but tyrosine is costly for the amount supplied. Incomplete comparisons for other ingredients limit a firm value judgment for the full blend.

Customer Satisfaction73

Customer ratings are very positive. The small review base means the satisfaction picture is still tentative.

Product Focus32

The nutrients contribute to normal thyroid function and energy metabolism when intake falls short. Those roles do not establish treatment of thyroid conditions, extra energy or general detox benefits.

Format
Capsule
Container
100 Capsule(s)
Per serving
$0.13
Customer rating
4.8 · 85 ratings
Report analysis

Goals

Impact
Moderate effect
C Ingredient FitF PathwaysA- EvidenceA+ Formulation Logic
Iodine · 150 mcgMagnesium · 100 mgRiboflavin · 10 mgThiamin · 10 mgVitamin B12 · 25 mcg
Study evidence
Iodine Adverse 3 studies
Magnesium Supportive 4 studies
Thiamin Disputed 12 studies
Impact
Moderate effect
C- Ingredient FitF PathwaysA- EvidenceA+ Formulation Logic
Vitamin B12 · 25 mcgVitamin B6 · 10 mgMolybdenum · 150 mcgSelenium · 70 mcgMagnesium · 100 mgZinc · 3 mgRiboflavin · 10 mg
Study evidence
Magnesium Supportive 19 studies
Selenium Supportive 10 studies
Zinc Supportive 30 studies
Everyday Health
Impact
Highest effect
B Ingredient FitA+ PathwaysA- EvidenceA+ Formulation Logic
Vitamin B12 · 25 mcgMagnesium · 100 mgSelenium · 70 mcgZinc · 3 mg
Study evidence
Magnesium Supportive 114 studies
Selenium Supportive 70 studies
Zinc Supportive 60 studies
Hair Health
Impact
Moderate effect
C- Ingredient FitD- PathwaysC EvidenceA+ Formulation Logic
Zinc · 3 mg
Study evidence
Copper Adverse 4 studies
Iodine No effect 1 study
Selenium Disputed 7 studies
Zinc Supportive 22 studies
Immunity
Impact
High effect
C- Ingredient FitD- PathwaysA- EvidenceA+ Formulation Logic
Magnesium · 100 mgZinc · 3 mgSelenium · 70 mcg
Study evidence
Magnesium Supportive 8 studies
Selenium Mixed 37 studies
Zinc Supportive 73 studies

Ingredients

IngredientAmount per servingScore
Thiamine (Thiamine Hydrochloride)
10 mg 65
Riboflavin
10 mg 58
Vitamin B6 (Pyridoxine Hydrochloride)
10 mg
Vitamin B12 (Cyanocobalamin)
25 mcg
Iodine (Atlantic Kelp, Potassium Iodide)
150 mcg 89
Magnesium (Magnesium Oxide)
100 mg
Zinc (Zinc Amino Acid Chelate)
3 mg
Selenium (Selenium Amino Acid Chelate)
70 mcg 61
Copper (Copper Amino Acid Chelate)
0.15 mg
Manganese (Manganese Amino Acid Chelate)
3 mg 82
Molybdenum (Molybdenum Amino Acid Chelate)
150 mcg 70
L-Tyrosine
150 mg 50
Multi Gland Complex (Heart, Kidney, Liver, Lung, Pancreas, Spleen)
35 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
Each serving provides 150 mcg of iodine at a low cost per serving. Its iodine comes from potassium iodide. The marine source lacks documented organic status or clean-water origin.
How this ingredient is rated

Active Ingredient Quality & Bioavailability73

The iodine is potassium iodide. A marine source is indicated, but organic status or a clean-water origin is not documented.
Iodine Form & Bioavailability
The iodine is potassium iodide.
Marine Source Purity & Sourcing
A marine source is indicated, but organic status or a clean-water origin is not documented.

Dose, Safety & Label Transparency100

The serving provides 150 mcg of iodine for daily support. The 150 mcg serving is below the stated upper intake limit.
Dosage Efficacy for Daily Support
The serving provides 150 mcg of iodine for daily support.
Dosage Safety & Upper Limits
The 150 mcg serving is below the stated upper intake limit.
Elemental Iodine Transparency
The iodine amount and potassium iodide source are stated.

Value100

The cost per serving is low.
Price Per Effective Serving
The cost per serving is low.
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value
The serving provides 3 mg of manganese, a moderate amount, at a low cost per serving. It uses Manganese Amino Acid Chelate, though the specific amino acid is not named.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

It uses Manganese Amino Acid Chelate, though the specific amino acid is not named.
Manganese Chemical Form
It uses Manganese Amino Acid Chelate, though the specific amino acid is not named.

Dose, Safety & Label Transparency86

The label clearly states 3 mg of manganese per serving, a moderate amount.
Manganese Dosage Efficacy & Safety
The serving supplies 3 mg of manganese, a moderate amount.
Elemental Weight Disclosure
The manganese amount is clearly stated as 3 mg per serving.

Value100

The cost per serving is low.
Price per Serving vs. Median
The cost per serving is low.
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value
A serving provides 150 mcg molybdenum at a low cost per serving. Molybdenum amino acid chelate is named, but its specific amino acid is unspecified.
How this ingredient is rated

Active Ingredient Quality & Bioavailability35

Molybdenum amino acid chelate is named, but its specific amino acid is unspecified. No TRAACS branded source is identified.
Molybdenum Chemical Form
Molybdenum amino acid chelate is named, but its specific amino acid is unspecified.
Branded or Patented Source
No TRAACS branded source is identified.

Dose, Safety & Label Transparency100

The serving provides 150 mcg molybdenum, below the adult upper limit.
Elemental Dose Optimization
A serving provides 150 mcg molybdenum.
Upper Limit (UL) Safety Compliance
The serving amount is below the adult upper limit.

Value80

The cost per serving is low.
Price per Effective Serving
The cost per serving is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Association of radioactive iodine treatment with survivorship symptoms and primary care utilisation in women of reproductive age with thyroid cancer: a retrospective cohort study.
    Devanarayan P; Hartman M; Partin M · Family medicine and community health · 2026
    Cohort study10,882 participantsEnergy forIodine
  2. Energy level and fatigue after surgery for thyroid cancer: A population-based study of patient-reported outcomes.
    Hughes DT; Reyes-Gastelum D; Kovatch KJ; Hamilton AS; Ward KC; Haymart MR · Surgery · 2020
    Cohort study2,584 participantsEnergy forIodine
  3. Health-Related Quality of Life in Differentiated Thyroid Cancer Survivors: A Cross-Sectional Study From Turkey.
    Gültekin A; Kahraman MY; Şengöz T; Şimşek FS · Head & neck · 2026
    Cross-sectional study202 participantsEnergy forIodine
  4. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  5. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  6. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  7. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  8. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  9. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  10. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  11. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  12. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy forRiboflavin
  13. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  14. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  15. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  16. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  17. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  18. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  19. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  20. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12