Mega-One

Mega-One

Source Naturals4.7 (656 ratings)
Format:Tablet Quantity: 180 Tablet(s) · 180 servings
Goals
$44.63 $0.24 per serving

Product analysis

55 out of 100

Mega-One supplies nutrients that may help with tiredness or shedding linked to inadequate intake. Its broad formula includes partly unspecified preparations, making ingredient quality harder to compare with a simpler supplement.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality44

Several B-vitamin forms and iodine are clearly identified, supporting more direct comparisons. Other preparations and source balances remain unclear, so quality varies in how confidently it can be judged.

Ingredient Transparency70

All active amounts are disclosed, making serving comparisons possible. Some forms and the relative shares of several mixed sources are unspecified, leaving gaps in the composition details.

Value For Money53

Several nutrients offer favorable value, including iodine and vitamin B6. Others, such as vitamin B5, choline and boron, are relatively expensive for their content, while many comparisons remain uncertain.

Customer Satisfaction79

Several hundred customers give strongly positive feedback. Their satisfaction does not establish the claimed range of health benefits.

Product Focus39

The many nutrients address several possible gaps relevant to tiredness, hair and normal metabolism. Those roles depend on nutritional circumstances and do not establish routine removal of unspecified toxins.

Format
Tablet
Container
180 Tablet(s)
Per serving
$0.24
Customer rating
4.7 · 656 ratings
Report analysis

Goals

Impact
Moderate effect
C+ Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Iodine · 150 mcgVitamin D · 10 mcgVitamin B5 · 85 mgMagnesium · 20 mgRiboflavin · 85 mgThiamin · 85 mgVitamin B12 · 90 mcgIron · 11 mgPotassium · 10 mg

Iron, B12, folate, B6, riboflavin, niacin, pantothenic acid and vitamin C address nutritional contributors to tiredness. The 11 mg iron serving supports oxygen transport, while magnesium contributes a much smaller amount at 20 mg. Large B-vitamin amounts do not imply a larger energy boost once needs are met.

How this product is rated for Energy

Ingredient fit66

9 ingredients contribute to the saved energy assessment, alongside a broader set of active ingredients that makes the focus less specific. The contributing amounts align reasonably well with the saved dose benchmarks, with some shortfalls.
Goal fit
9 ingredients contribute to the saved energy assessment, alongside a broader set of active ingredients that makes the focus less specific.
Dose adequacy
The contributing amounts align reasonably well with the saved dose benchmarks, with some shortfalls.

Pathways0

No reviewed functional area has a recorded contribution. No functional area reaches the saved coverage threshold.
Depth
No reviewed functional area has a recorded contribution.
Breadth
No functional area reaches the saved coverage threshold.

Evidence97

Iron provides the strongest qualifying evidence in the saved assessment; the relevant benefit remains limited to its reviewed outcome. The saved preparation review is limited by Iodine, which was not matched to the studied preparation.
Evidence strength
Iron provides the strongest qualifying evidence in the saved assessment; the relevant benefit remains limited to its reviewed outcome.
Studied preparation
The saved preparation review is limited by Iodine, which was not matched to the studied preparation.

Formulation logic100

The contributing ingredients can work alone or have their required partner present. No ingredient conflicts were recorded in the saved assessment. All contributing ingredients reach the saved meaningful-dose threshold.
Partner coverage
The contributing ingredients can work alone or have their required partner present.
Conflicts
No ingredient conflicts were recorded in the saved assessment.
Effective doses
All contributing ingredients reach the saved meaningful-dose threshold.
Study evidence
Iodine Adverse 3 studies
Iron Supportive 74 studies
Magnesium Supportive 4 studies
Potassium Supportive 2 studies
Thiamin Disputed 12 studies
Vitamin D Supportive 32 studies
Impact
High effect
C- Ingredient FitD PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 90 mcgVitamin D · 10 mcgZinc · 15 mgIron · 11 mgVitamin C · 250 mg

Zinc can help address shedding caused by inadequate zinc intake, and iron can help when iron deficiency is responsible. Biotin has a similarly limited role in deficiency-related shedding; higher amounts do not establish extra regrowth with adequate intake. The remaining nutrient functions do not establish routine hair growth. The saved findings mainly recognize nutrient amounts and antioxidant-related coverage, whose practical benefit remains dependent on the specific nutritional circumstances.

How this product is rated for Hair Health

Ingredient fit59

The formula contains recognized hair-related ingredients, but their practical relevance depends on nutritional need and usable amounts. Recognized hair-related ingredients sit alongside ingredients serving other purposes, so the formula has a broader focus.
Goal fit
Recognized hair-related ingredients sit alongside ingredients serving other purposes, so the formula has a broader focus.
Dose adequacy
Some recognized ingredients have low or unresolved amounts, limiting how much the serving contributes.

Pathways48

Antioxidant-related nutrient coverage is the strongest finding, but normal antioxidant functions do not establish hair regrowth. Meaningful coverage centers on antioxidant-related functions, with limited coverage of the other hair pathways.
Depth
Antioxidant-related nutrient coverage is the strongest finding, but normal antioxidant functions do not establish hair regrowth.
Breadth
Meaningful coverage centers on antioxidant-related functions, with limited coverage of the other hair pathways.

Evidence97

Zinc is the leading recognized ingredient; its practical hair benefit is relevant to deficiency-related shedding, rather than routine regrowth. Preparation matching does not establish a trial of the complete product.
Evidence strength
Zinc is the leading recognized ingredient; its practical hair benefit is relevant to deficiency-related shedding, rather than routine regrowth.
Studied preparation
Recognized preparations meet the saved comparison criteria except iodine; this does not demonstrate hair benefits from the complete formula.

Formulation logic98

The recognized ingredients have no missing required partner or configured conflict. Vitamin A has low or unresolved amounts in the saved findings; the other recognized ingredients meet its amount criterion.
Partner coverage
No required partner is missing among the recognized ingredients; this does not establish extra benefit from combining them.
Conflicts
No configured ingredient conflict was identified in the supplied findings.
Effective doses
Vitamin A has low or unresolved amounts in the saved findings; the other recognized ingredients meet its amount criterion.
Study evidence
Biotin Supportive 4 studies
Copper Adverse 4 studies
Folate Mixed 15 studies
Iodine No effect 1 study
Iron Disputed 25 studies
Niacin Disputed 2 studies
Selenium Disputed 7 studies
Vitamin A Disputed 13 studies
Vitamin D Disputed 34 studies
Vitamin E No effect 3 studies
Zinc Supportive 22 studies
Impact
High effect
D+ Ingredient FitB+ PathwaysA+ EvidenceA+ Formulation Logic
Folate · 714 mcg DFEVitamin B12 · 90 mcgVitamin B6 · 85 mgMolybdenum · 100 mcgSelenium · 50 mcgMagnesium · 20 mgVitamin E · 67 mgZinc · 15 mgVitamin C · 250 mgCholine · 85 mgRiboflavin · 85 mg

Folate and selenium have limited connections to elimination of specific metals in exposed populations, with low nutrient status relevant to some findings. These results do not establish routine removal of unspecified toxins. Choline has a nutritional role in liver function, but its amount is unresolved here; the other vitamins' normal metabolic roles do not establish extra toxin clearance.

How this product is rated for Liver & Detox

Ingredient fit54

Ten ingredients are retained within a broad nutrient formula, including choline with an unresolved amount.
Goal fit
Ten ingredients are retained within a broad nutrient formula, including choline with an unresolved amount.
Dose adequacy
Choline's unresolved amount receives no amount recognition; other retained nutrients receive mixed recognition.

Pathways83

The retained findings concentrate on methyl-group supply. These category findings do not demonstrate measured toxin removal.
Depth
Methyl-group supply is the best-covered category in the saved findings.
Breadth
Coverage reaches the threshold for liver integrity, methyl-group supply and enzyme support; gut binding and elimination receives no coverage.

Evidence97

Folate leads the retained evidence finding, but its toxin-related studies concern arsenic exposure and specific folic-acid regimens.
Evidence strength
Folate leads the retained evidence finding, but its toxin-related studies concern arsenic exposure and specific folic-acid regimens.
Studied preparation
Molybdenum, riboflavin and B6 are not accepted as studied in the saved preparation finding; other retained preparations are accepted.

Formulation logic98

No required partner is missing and no configured conflict is triggered. Amount findings do not establish clinical toxin-clearance doses.
Partner coverage
The retained ingredients require no missing partner; combined presence does not establish added detoxification benefit.
Conflicts
No configured conflict is triggered, without establishing overall safety.
Effective doses
9 of the 10 retained ingredients meet the amount threshold; choline has an unresolved amount and does not.
Study evidence
Choline Supportive 6 studies
Folate Supportive 16 studies
Magnesium Supportive 19 studies
Selenium Supportive 10 studies
Vitamin C Supportive 9 studies
Vitamin E Supportive 23 studies
Zinc Supportive 30 studies
Impact
High effect
C+ Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 90 mcgNiacin · 85 mgVitamin B12 · 90 mcgRiboflavin · 85 mgThiamin · 85 mgVitamin B5 · 85 mgVitamin B6 · 85 mgVitamin D · 10 mcgZinc · 15 mgMagnesium · 20 mg

Iodine can restore normal thyroid function when low iodine intake causes hypothyroidism. Iron has a narrower connection when iron-deficiency anaemia lowers thyroid hormones and cold-related heat production. The other vitamins' normal metabolic roles do not establish increased calorie use when intake is adequate, and chromium's glucose-related findings are not proof of thermogenesis.

How this product is rated for Metabolism Support

Ingredient fit70

Twelve nutrients are retained within a broad formula.
Goal fit
Twelve nutrients are retained within a broad formula.
Dose adequacy
Retained amounts receive mixed recognition; magnesium and vitamin D fall below inclusion thresholds.

Pathways4

The saved findings provide limited coverage in insulin sensitivity and metabolic hormones.
Depth
Insulin sensitivity and metabolic hormones receives limited coverage, without establishing increased calorie use.
Breadth
No evaluated category reaches the breadth threshold.

Evidence100

Thiamin leads the retained evidence finding, while its normal nutrient role does not establish increased energy expenditure above adequate intake.
Evidence strength
Thiamin leads the retained evidence finding, while its normal nutrient role does not establish increased energy expenditure above adequate intake.
Studied preparation
Retained preparations with usable amounts are accepted in the saved finding; this does not establish superior effects from particular nutrient forms.

Formulation logic100

No required partner is missing and no configured conflict is triggered. Amount recognition does not establish sustained thermogenesis.
Partner coverage
Retained ingredients require no missing partner; combining them does not establish additional thermogenic benefit.
Conflicts
No configured conflict is triggered, without establishing overall safety or personal suitability.
Effective doses
All 12 retained ingredients meet the comparison amount threshold; this is not proof of a clinically effective thermogenic dose.
Study evidence
Biotin Supportive 5 studies
Chromium Supportive 47 studies
Iodine Mixed 17 studies
Magnesium Supportive 61 studies
Niacin Supportive 17 studies
Selenium Mixed 28 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies
Vitamin D Supportive 65 studies
Zinc Supportive 12 studies

Ingredients

IngredientAmount per servingScore
Vitamin A
2850 mcg
Vitamin C (Calcium Ascorbate, Manganese Ascorbic Acid Complex, Zinc Ascorbate)
250 mg
Vitamin D3 (Cholecalciferol)
10 mcg
Vitamin E (D-Alpha-Tocopheryl Succinate)
67 mg
Thiamin
85 mg 56
Riboflavin
85 mg 72
Niacin (Niacinamide)
85 mg 73
Vitamin B6 (Pyridoxine Hydrochloride)
85 mg 73
Folate (Folic Acid)
714 mcg DFE
Vitamin B12 (Cyanocobalamin)
90 mcg
Biotin
90 mcg
Pantothenic Acid (Calcium D-Pantothenate)
85 mg 70
Calcium (Calcium Ascorbate, Calcium Carbonate)
40 mg
Iron (Iron Fumarate)
11 mg 57
Iodine (Potassium Iodide)
150 mcg 100
Magnesium (Magnesium Citrate, Magnesium Oxide)
20 mg
Zinc (Zinc Ascorbate)
15 mg
Selenium (L-Selenomethionine, Sodium Selenite)
50 mcg
Copper (Copper Sebacic Acid Complex)
1 mg 62
Manganese (Manganese Ascorbic Acid Complex)
6 mg 60
Chromium (Chromium Amino Acid Chelate)
100 mcg 42
Molybdenum (Molybdenum Amino Acid Complex)
100 mcg 70
Potassium (Potassium Citrate)
10 mg
Choline Bitartrate
85 mg 55
PABA
85 mg 84
Inositol
85 mg
Citrus Bioflavonoid Complex
25 mg
Rutin
21 mg 83
Hesperidin
5 mg
Boron (Boron Amino Acid Complex)
1 mg 51
Adults 18–50 Women
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
A serving supplies 150 mcg of iodine as potassium iodide. The whole-product price is about $0.25 per serving.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

The iodine is supplied as potassium iodide, a form favored by the evaluation.
Iodine Form & Bioavailability
Potassium iodide is the named chemical form, and the evaluation favors it among the forms it considers.
Marine Source Purity & Sourcing
No marine source is recorded, so the marine-specific sourcing criterion does not apply; this does not establish contaminant absence.

Dose, Safety & Label Transparency100

A serving provides 150 mcg of iodine. The amount itself is disclosed.
Dosage Efficacy for Daily Support
A serving provides 150 mcg of iodine.
Dosage Safety & Upper Limits
The evaluation does not flag the amount as exceeding its general upper limit; individual safety is not established.
Elemental Iodine Transparency
The supplied facts identify 150 mcg of iodine per serving and name potassium iodide as the source.

Value100

The whole product costs about $0.25 per serving.
Price Per Effective Serving
The whole product costs about $0.25 per serving.
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
A serving provides 6 mg of manganese, but its form is not identified in the saved information. The whole-product serving costs about $0.25.
How this ingredient is rated

Active Ingredient Quality & Bioavailability0

The manganese form is not identified in the saved information.
Manganese Chemical Form
The manganese form is not identified in the saved information.

Dose, Safety & Label Transparency100

The saved serving amount is 6 mg of elemental manganese.
Manganese Dosage Efficacy & Safety
The declared elemental manganese amount is 6 mg per serving.
Elemental Weight Disclosure
The elemental manganese amount is stated as 6 mg per serving.

Value100

The whole-product serving costs about $0.25 and provides 6 mg of manganese.
Price per Serving vs. Median
The recorded whole-product cost is about $0.25 per serving.
PABA · 85 mg OverallScore84
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value
Each serving provides 85 mg of PABA, with the amount separately listed. Using the whole-product price, the cost works out to about $0.29 per 100 mg of PABA.
How this ingredient is rated

Active Ingredient Quality & Bioavailability80

The saved facts identify PABA, but do not establish a grade or purity designation.
PABA Source & Grade
PABA is named in the saved facts; a grade or purity designation is not established.

Dose, Safety & Label Transparency95

PABA is separately listed at 85 mg per serving. The saved ingredient information shows none of the three additive categories checked.
PABA Dosage Alignment
The serving provides 85 mg of PABA.
Label Disclosure Clarity
The PABA amount is separately disclosed as 85 mg per serving.
Additive and Excipient Quality
The saved ingredient information shows no FD&C dyes, titanium dioxide or hydrogenated oils.

Value70

Using the whole-product price, the cost works out to about $0.29 per 100 mg of PABA.
Price per 100mg PABA
Using the whole-product price, the cost works out to about $0.29 per 100 mg of PABA.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Association of radioactive iodine treatment with survivorship symptoms and primary care utilisation in women of reproductive age with thyroid cancer: a retrospective cohort study.
    Devanarayan P; Hartman M; Partin M · Family medicine and community health · 2026
    Cohort study10,882 participantsEnergy forIodine
  2. Energy level and fatigue after surgery for thyroid cancer: A population-based study of patient-reported outcomes.
    Hughes DT; Reyes-Gastelum D; Kovatch KJ; Hamilton AS; Ward KC; Haymart MR · Surgery · 2020
    Cohort study2,584 participantsEnergy forIodine
  3. Health-Related Quality of Life in Differentiated Thyroid Cancer Survivors: A Cross-Sectional Study From Turkey.
    Gültekin A; Kahraman MY; Şengöz T; Şimşek FS · Head & neck · 2026
    Cross-sectional study202 participantsEnergy forIodine
  4. Large-dose intravenous ferric carboxymaltose injection for iron deficiency anemia in heavy uterine bleeding: a randomized, controlled trial.
    Van Wyck DB; Mangione A; Morrison J; Hadley PE; Jehle JA; Goodnough LT · Transfusion · 2010
    Randomized trial477 participantsEnergy forIron
  5. The Effect of Parenteral or Oral Iron Supplementation on Fatigue, Sleep, Quality of Life and Restless Legs Syndrome in Iron-Deficient Blood Donors: A Secondary Analysis of the IronWoMan RCT.
    Macher S; Herster C; Holter M; Moritz M; Matzhold EM; Stojakovic T; Pieber TR; Schlenke P; Drexler C; Amrein K · Nutrients · 2021
    Randomized trial176 participantsEnergy forIron
  6. Ferric carboxymaltose vs. oral iron in the treatment of pregnant women with iron deficiency anemia: an international, open-label, randomized controlled trial (FER-ASAP).
    Breymann C; Milman N; Mezzacasa A; Bernard R; Dudenhausen J; FER-ASAP investigators · Journal of perinatal medicine · 2018
    Randomized trial252 participantsEnergy forIron
  7. Effect of iron therapy on fatigue symptoms in non-anaemic iron deficient women of reproductive age- A Randomized Controlled Trial.
    Sultana N; Bajwa FA; Sikandar MZ; Haider MM; Majeed T · JPMA. The Journal of the Pakistan Medical Association · 2026
    Randomized trial164 participantsEnergy forIron
  8. Intravenous iron isomaltoside treatment of women suffering from severe fatigue after postpartum hemorrhage.
    Holm C; Thomsen LL; Langhoff-Roos J · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019
    Randomized trial85 participantsEnergy forIron
  9. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  10. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  11. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  12. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  13. [Efficacy of potassium N-acetylaminosuccinate (Cogitum) in the treatment of asthenic syndrome: results of double-blind placebo-controlled trial].
    Esin RG; Khayrullin IK; Esin OR; Fatykhova AF; Gismatullina EI; Isaeva YN · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2023
    Randomized trial37 participantsEnergy forPotassium
  14. Human resting energy expenditure in relation to dietary potassium.
    Dériaz O; Thériault G; Lavallée N; Fournier G; Nadeau A; Bouchard C · The American journal of clinical nutrition · 1991
    Randomized trial8 participantsEnergy forPotassium
  15. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  16. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  17. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  18. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  19. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  20. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin