Advanced Adult Multivitamin & Mineral with 5-MTHF

Advanced Adult Multivitamin & Mineral with 5-MTHF

Kirkman4.7 (73 ratings)
Format:Capsule Quantity: 180 Capsule(s) · 90 servings
Goals
$44.00 $0.48 per serving

About this product

Broad nutritional coverage is the main appeal when dietary intake is uneven. B vitamins and magnesium support normal energy use, while folate and B12 contribute to blood formation. Zinc, selenium, vitamin C and vitamin D add support for ordinary immune function.

Zinc citrate and potassium iodide are favorable mineral choices, and the folate source is clearly named. The 5-MTHF form does not establish better general-health results by itself. The unnamed proprietary blend and missing proportions for vitamin A, vitamin C and magnesium leave parts of the formula difficult to compare.

The 5 mg iron contribution is small, so the formula is less suited to someone relying on it for substantial iron support. Zinc in the same serving may also compete with iron absorption. Value varies by nutrient, making the overall mixture more useful for covering several gaps than for buying a particular nutrient economically.

Who is it for
  • Adults with several dietary nutrient gaps
  • People seeking broad nutritional support with a small iron contribution
Best for
  • Normal energy metabolism
  • General nutrient coverage
  • Blood formation and immune nutrition

Pros

  • B vitamins and magnesium support normal energy use
  • Zinc citrate and potassium iodide are favorable mineral choices
  • Folate and B12 contribute to normal blood formation

Cons

  • Proprietary blend contents are not individually identified
  • Several ingredient mixtures have undisclosed proportions
  • The small iron amount limits substantial iron support
  • Value is uneven across individual nutrients

Warnings

  • Zinc in the same serving may compete with iron absorption, which matters if you are relying on its small iron contribution.

Product analysis

51 out of 100

Advanced Adult Multivitamin & Mineral with 5-MTHF helps cover nutritional needs relevant to normal metabolism, blood formation and immune function. Its broad formula includes an undisclosed blend, making the added ingredients harder to judge.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality50

Several minerals use favorable forms, including iodine, zinc, chromium and molybdenum. Many other preparations cannot be compared confidently for quality, and mixed-source proportions remain unclear.

Ingredient Transparency77

All declared amounts and most preparations are stated. The proprietary blend and relative shares of several mixed sources are undisclosed, leaving gaps in the full composition.

Value For Money41

Value is mixed, with molybdenum more reasonably priced than selenium and chromium. Several other comparisons are moderate or uncertain, so no clear value advantage is established across the full formula.

Customer Satisfaction71

The small set of customer reviews is strongly positive. The limited count gives a narrow view of satisfaction and does not establish broad health benefits.

Product Focus13

The broad nutrient mix addresses many normal functions, particularly when intake is inadequate. Its undisclosed blend and wide range of intended uses make individual extra benefits harder to distinguish.

Format
Capsule
Container
180 Capsule(s)
Per serving
$0.48
Customer rating
4.7 · 73 ratings
Report analysis

Goals

Impact
Highest effect
B+ Ingredient FitA+ PathwaysA- EvidenceA+ Formulation Logic
Folate · 666 mcg DFEVitamin B12 · 120 mcgVitamin D · 25 mcgMagnesium · 200 mgSelenium · 70 mcgZinc · 27 mgVitamin C · 350 mg

B vitamins, folate and magnesium provide nutrients involved in metabolism and blood formation, while vitamin D contributes to mineral nutrition. Zinc, selenium and vitamin C add immune and antioxidant nutritional roles, and iodine helps fill a low intake. These are conditional nutritional contributions; the supplied information does not establish that 5-MTHF or other named forms provide superior general-health benefits.

How this product is rated for Everyday Health

Ingredient fit81

The relevant ingredients are focused on the nutritional roles described here. The counted ingredients supply differing amounts relative to their saved comparisons, so their nutritional contributions vary.
Goal fit
The relevant ingredients are focused on the nutritional roles described here.
Dose adequacy
The counted ingredients supply differing amounts relative to their saved comparisons, so their nutritional contributions vary.

Pathways100

The strongest saved contribution concerns energy metabolism cofactors, reflecting the relevant nutrient amounts rather than a guaranteed health outcome. Four areas contribute meaningfully in the saved findings, reflecting the mix of relevant nutrients.
Depth
The strongest saved contribution concerns energy metabolism cofactors, reflecting the relevant nutrient amounts rather than a guaranteed health outcome.
Breadth
Four areas contribute meaningfully in the saved findings, reflecting the mix of relevant nutrients.

Evidence86

Magnesium leads the saved evidence finding; its supported role here is conditional nutrient availability rather than additional benefit above adequate intake.
Evidence strength
Magnesium leads the saved evidence finding; its supported role here is conditional nutrient availability rather than additional benefit above adequate intake.
Studied preparation
The counted preparations satisfy the saved preparation check; this does not establish superiority of their forms or delivery methods.

Formulation logic100

The counted ingredients can contribute independently or have the partners required by the supplied findings. No configured ingredient conflict was identified in the supplied findings.
Partner coverage
The counted ingredients can contribute independently or have the partners required by the supplied findings.
Conflicts
No configured ingredient conflict was identified in the supplied findings.
Effective doses
All ingredients counted in this check meet its minimum amount criterion; that criterion does not prove a clinically effective dose.
Study evidence
Folate Supportive 80 studies
Magnesium Supportive 114 studies
Selenium Supportive 70 studies
Vitamin C Supportive 56 studies
Vitamin D Supportive 115 studies
Zinc Supportive 60 studies
Immunity
Impact
Highest effect
C Ingredient FitA+ PathwaysA+ EvidenceA+ Formulation Logic
Magnesium · 200 mgVitamin C · 350 mgZinc · 27 mgVitamin A · 1500 mcg RAEVitamin D · 25 mcgSelenium · 70 mcg

Zinc, Vitamin D, Selenium contribute to normal immune-cell function and regulation. Vitamin A also supports protective barriers. Vitamin B6, Vitamin B12, Folate, Iron can help restore immune processes impaired by low intake, without establishing extra protection when intake is adequate. Vitamin C has modest regular-use cold-duration support, without establishing infection prevention. Higher Vitamin B6 amounts do not establish extra benefit or suitability.

How this product is rated for Immunity

Ingredient fit64

Vitamin C connects the formula to immunity. Amounts provide uneven support against the supplied comparisons; smaller or unresolved quantities limit some contributions.
Goal fit
Relevant immune nutrients are included within a broader formula with other active ingredients.
Dose adequacy
Amounts provide uneven support against the supplied comparisons; smaller or unresolved quantities limit some contributions.

Pathways100

The strongest saved finding concerns barrier and antimicrobial defense.
Depth
The strongest saved finding concerns barrier and antimicrobial defense.
Breadth
The broader saved findings cover barrier and antimicrobial defense, innate immune cell activity, lymphocyte function and immune regulation, oxidative and inflammatory balance.

Evidence100

Vitamin C provides the strongest saved evidence finding. Nutritional function or modest regular-use symptom support does not establish general infection prevention.
Evidence strength
Vitamin C drives the strongest saved evidence finding; the practical support remains bounded by its specific nutritional or regular-use role.
Studied preparation
The saved finding accepts the declared forms without establishing that they outperform other forms.

Formulation logic100

No unmet ingredient partner or configured conflict was identified. The included contributors meet the saved minimum amount criterion; this does not establish clinical effectiveness.
Partner coverage
The included ingredients have no unmet partner requirement in the supplied findings.
Conflicts
No configured ingredient conflict was identified in the supplied findings.
Effective doses
The included contributors meet the saved minimum amount criterion; this does not establish clinical effectiveness.
Study evidence
Iron Supportive 23 studies
Magnesium Supportive 8 studies
Selenium Mixed 37 studies
Vitamin A Supportive 107 studies
Vitamin C Supportive 53 studies
Vitamin D Supportive 85 studies
Vitamin E Supportive 21 studies
Zinc Supportive 73 studies
Impact
Moderate effect
C+ Ingredient FitF PathwaysA EvidenceA+ Formulation Logic
Iodine · 150 mcgVitamin D · 25 mcgVitamin B5 · 10 mgMagnesium · 200 mgRiboflavin · 6 mgThiamin · 6 mgVitamin B12 · 120 mcgIron · 5 mg

B vitamins support the normal release of energy from food, while folate and B12 support nutritional needs relevant to tiredness. Magnesium, iron and vitamin C add nutritional support; CoQ10 has no resolved amount, so its contribution is uncertain.

How this product is rated for Energy

Ingredient fit65

The relevant nutrients support energy-related nutrition within a blend that also serves other goals. The declared amounts provide partial support within the saved comparison ranges.
Goal fit
The relevant nutrients support energy-related nutrition within a blend that also serves other goals.
Dose adequacy
The declared amounts provide partial support within the saved comparison ranges.

Pathways0

The saved assessment assigns the contribution to nutritional adequacy rather than a configured energy pathway. No configured energy pathway reaches the saved coverage threshold.
Depth
The saved assessment assigns the contribution to nutritional adequacy rather than a configured energy pathway.
Breadth
No configured energy pathway reaches the saved coverage threshold.

Evidence94

Vitamin D is the strongest evidence contributor in the saved assessment. Practical fatigue benefits depend on the relevant nutritional or study context. Most assessed preparations are accepted; iodine is not matched to a studied preparation.
Evidence strength
Vitamin D is the strongest evidence contributor in the saved assessment. Practical fatigue benefits depend on the relevant nutritional or study context.
Studied preparation
Most assessed preparations are accepted; iodine is not matched to a studied preparation.

Formulation logic100

No configured ingredient conflict was found. All assessed contributing ingredients meet the saved minimum amount threshold.
Partner coverage
The assessed ingredients can contribute alone or have their required partner.
Conflicts
No configured ingredient conflict was found.
Effective doses
All assessed contributing ingredients meet the saved minimum amount threshold.
Study evidence
Iodine Adverse 3 studies
Iron Supportive 74 studies
Magnesium Supportive 4 studies
Thiamin Disputed 12 studies
Vitamin D Supportive 32 studies
Impact
Highest effect
C Ingredient FitA+ PathwaysA+ EvidenceA+ Formulation Logic
Folate · 666 mcg DFEVitamin B12 · 120 mcgVitamin B6 · 6 mgMolybdenum · 75 mcgSelenium · 70 mcgMagnesium · 200 mgVitamin E · 20 mgZinc · 27 mgVitamin C · 350 mgRiboflavin · 6 mg

Folate and selenium have narrow metal-elimination findings in low-status or exposed populations, rather than evidence for routine toxin removal with adequate nutrition. B12 supports methyl metabolism, while other B vitamins, zinc, magnesium and molybdenum support normal enzymes. Vitamin C has antioxidant functions without an established general clearance benefit. Vitamin E is excluded for its small amount.

How this product is rated for Liver & Detox

Ingredient fit62

Nine ingredients receive recognition within a broader multinutrient formula, with partial overall amounts.
Goal fit
Relevant nutrients sit alongside many other actives and linked purposes, reducing focus.
Dose adequacy
The nine included amounts provide partial overall exposure coverage; excluded vitamin E supplies none.

Pathways98

Enzyme induction leads, with conjugation and methyl supply also substantially represented. Liver integrity is smaller.
Depth
Enzyme induction has the strongest saved coverage.
Breadth
Enzyme induction, conjugation and methyl supply meet the coverage threshold.

Evidence97

Folate leads the evidence finding, while molybdenum, riboflavin and B6 lack studied preparation matches.
Evidence strength
Folate leads the evidence comparison, with metal-exposure findings that do not establish a general cleanse effect.
Studied preparation
Most included preparations match; molybdenum, riboflavin and B6 do not.

Formulation logic100

All nine included ingredients meet the exposure threshold, with no missing partner or listed conflict.
Partner coverage
No credited ingredient lacks a required partner.
Conflicts
No listed ingredient conflict was found.
Effective doses
All nine included ingredients meet the minimum exposure threshold; excluded vitamin E is outside this finding.
Study evidence
Folate Supportive 16 studies
Magnesium Supportive 19 studies
Selenium Supportive 10 studies
Vitamin C Supportive 9 studies
Vitamin E Supportive 23 studies
Zinc Supportive 30 studies
Impact
High effect
B- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 100 mcgNiacin · 20 mg NEVitamin B12 · 120 mcgRiboflavin · 6 mgThiamin · 6 mgVitamin B5 · 10 mgVitamin B6 · 6 mgVitamin D · 25 mcgZinc · 27 mgMagnesium · 200 mg

B vitamins and magnesium support normal energy metabolism, while iodine and selenium contribute to thyroid function. Iron can help restore reduced heat production when iron-deficiency anaemia is present. These roles do not establish extra energy expenditure with adequate nutrient intake. CoQ10 and resveratrol remain unresolved in the imported ingredient facts, so their presence and amounts cannot be assumed.

How this product is rated for Metabolism Support

Ingredient fit70

B vitamins and minerals provide the ingredient connections retained in the saved findings. Their amount comparisons describe the declared serving rather than a demonstrated metabolism-boosting regimen.
Goal fit
B vitamins and minerals account for the goal-related ingredient findings, while the product's range of other uses and other active ingredients make it less focused on this goal.
Dose adequacy
The confirmed nutrient amounts receive partial amount findings; unresolved CoQ10 and resveratrol facts cannot supply known amounts.

Pathways5

The strongest saved connection concerns insulin sensitivity and metabolic hormones; changes here do not by themselves establish increased energy expenditure. None meets the saved coverage threshold.
Depth
The strongest saved connection concerns insulin sensitivity and metabolic hormones; changes here do not by themselves establish increased energy expenditure.
Breadth
No pathway meets the saved coverage threshold; this is distinct from proving the ingredients have no biological effects.

Evidence100

Vitamin B1 (Thiamin) provides the strongest saved evidence finding among the qualifying amounts; this does not itself demonstrate a general metabolism boost.
Evidence strength
Vitamin B1 (Thiamin) provides the strongest saved evidence finding among the qualifying amounts; this does not itself demonstrate a general metabolism boost.
Studied preparation
The qualifying ingredients are treated as matching studied preparations in the saved findings; preparation matching alone does not establish a rise in energy expenditure.

Formulation logic100

The retained ingredients have no missing required partner or matched configured conflict. They meet the saved amount criterion, which does not establish additional calorie burning.
Partner coverage
The included ingredient contributions do not lack a required partner; this does not establish extra benefit from combining them.
Conflicts
No configured ingredient conflict was matched in the supplied facts; this finding does not establish overall safety.
Effective doses
All ingredients retained for this amount check meet its comparison criterion; that criterion is not a proven dose for increased calorie burning.
Study evidence
Biotin Supportive 5 studies
Chromium Supportive 47 studies
Iodine Mixed 17 studies
Magnesium Supportive 61 studies
Niacin Supportive 17 studies
Selenium Mixed 28 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies
Vitamin D Supportive 65 studies
Zinc Supportive 12 studies
Impact
High effect
D+ Ingredient FitD+ PathwaysA EvidenceA+ Formulation Logic
Magnesium · 200 mgZinc · 27 mgVitamin D · 25 mcg

Zinc offers a nutritional route to restoring testosterone when low intake has impaired normal hormone function. Magnesium’s exercise-specific findings and selenium’s infertility findings do not establish a routine increase in unselected adults. Vitamin D findings are inconsistent outside initially deficient groups, and B6’s enzyme role does not prove a hormone effect. Vitamin E is present at a small amount relative to the comparison threshold.

How this product is rated for Testosterone Support

Ingredient fit54

Zinc anchors the fit, with smaller or unresolved amounts limiting some contributions. The wider formula also affects how concentrated it is on testosterone-related roles.
Goal fit
The formula combines ingredients considered for testosterone with many actives serving broader purposes.
Dose adequacy
The ingredient amounts provide partial coverage of the comparison ranges, with differing contributions between ingredients.

Pathways50

Free-testosterone availability is the leading represented route. Coverage across the other specified routes is limited.
Depth
Free-testosterone availability is the leading represented route; the ingredient-specific evidence limits still apply.
Breadth
One specified route reaches the required coverage, leaving the represented action narrow.

Evidence92

Zinc provides the clearest nutritional connection through correcting inadequate intake. Other included mechanisms or selected-population findings do not establish generalized testosterone enhancement.
Evidence strength
Zinc anchors the evidence finding through correcting inadequate intake, rather than established enhancement above nutrient adequacy.
Studied preparation
Vitamin B6 lacks a studied preparation match; the remaining included preparations satisfy the supplied comparison.

Formulation logic100

The included ingredients meet the amount and partner checks, with no specified conflict triggered.
Partner coverage
No required supporting partner is missing for the included ingredients.
Conflicts
None of the specified ingredient conflict checks was triggered.
Effective doses
The included ingredients meet the minimum amount comparison, which is not a proven testosterone-enhancing dose.
Study evidence
Magnesium Disputed 5 studies
Selenium No effect 16 studies
Vitamin D Supportive 56 studies
Vitamin E Disputed 3 studies
Zinc Disputed 7 studies

Ingredients

IngredientAmount per servingScore
Vitamin A (Beta-Carotene, Retinol)
1500 mcg RAE
Vitamin C (Ascorbic Acid, Magnesium Ascorbate)
350 mg
Vitamin D3 (Cholecalciferol)
25 mcg
Vitamin E (Alpha-Tocopherol)
20 mg
Vitamin B1 (Thiamine Mononitrate)
6 mg
Vitamin B2 (Riboflavin)
6 mg
Vitamin B3 (Niacinamide)
20 mg NE
Vitamin B6 (Pyridoxine Hydrochloride)
6 mg
Folate (Calcium L-5-Methyltetrahydrofolate)
666 mcg DFE
Vitamin B12 (Cyanocobalamin)
120 mcg 21
Biotin
100 mcg
Vitamin B5 (D-Calcium Pantothenate)
10 mg
Iron (Ferrous Bisglycinate Chelate)
5 mg 63
Iodine (Potassium Iodide)
150 mcg 90
Magnesium (Magnesium Ascorbate, Magnesium Bisglycinate Chelate, Magnesium Oxide)
200 mg
Zinc (Zinc Citrate)
27 mg 71
Selenium (Selenium Glycinate Complex)
70 mcg 51
Manganese (Manganese Citrate)
2 mg
Chromium (Chromium Nicotinate Glycinate Chelate)
120 mcg 47
Molybdenum (Molybdenum Glycinate)
75 mcg 85
Kirkman Proprietary Blend
50 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value
A- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB+ Value
B+ Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyC Value
A substantial 27 mg zinc serving comes from a clearly identified citrate source. The unknown copper amount leaves mineral balance unresolved, while the whole-product serving costs about $0.49.
How this ingredient is rated

Active Ingredient Quality & Bioavailability80

The clearly identified citrate source is a favorable part of the zinc profile.
Zinc Form Bioavailability
Zinc citrate is the sole identified source, allowing a direct comparison of the zinc form.

Dose, Safety & Label Transparency67

The substantial zinc amount is clearly stated; copper information matters when interpreting the mineral balance.
Elemental Dose Transparency
The label clearly states 27 mg elemental zinc per serving and identifies its source form, rather than giving only a compound weight.
Zinc Dosage Safety & Effectiveness
The serving supplies a substantial, clearly measured 27 mg of elemental zinc.
Zinc-to-Copper Mineral Balance
Copper is unknown, so zinc-to-copper balance cannot be assessed; the saved information does not establish zero copper.

Value60

The whole-product serving cost is in the middle of this value comparison.
Price Per Serving Efficiency
About $0.49 buys one labeled whole-product serving, not zinc alone; the price does not establish quality.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Association of radioactive iodine treatment with survivorship symptoms and primary care utilisation in women of reproductive age with thyroid cancer: a retrospective cohort study.
    Devanarayan P; Hartman M; Partin M · Family medicine and community health · 2026
    Cohort study10,882 participantsEnergy forIodine
  2. Energy level and fatigue after surgery for thyroid cancer: A population-based study of patient-reported outcomes.
    Hughes DT; Reyes-Gastelum D; Kovatch KJ; Hamilton AS; Ward KC; Haymart MR · Surgery · 2020
    Cohort study2,584 participantsEnergy forIodine
  3. Health-Related Quality of Life in Differentiated Thyroid Cancer Survivors: A Cross-Sectional Study From Turkey.
    Gültekin A; Kahraman MY; Şengöz T; Şimşek FS · Head & neck · 2026
    Cross-sectional study202 participantsEnergy forIodine
  4. Large-dose intravenous ferric carboxymaltose injection for iron deficiency anemia in heavy uterine bleeding: a randomized, controlled trial.
    Van Wyck DB; Mangione A; Morrison J; Hadley PE; Jehle JA; Goodnough LT · Transfusion · 2010
    Randomized trial477 participantsEnergy forIron
  5. The Effect of Parenteral or Oral Iron Supplementation on Fatigue, Sleep, Quality of Life and Restless Legs Syndrome in Iron-Deficient Blood Donors: A Secondary Analysis of the IronWoMan RCT.
    Macher S; Herster C; Holter M; Moritz M; Matzhold EM; Stojakovic T; Pieber TR; Schlenke P; Drexler C; Amrein K · Nutrients · 2021
    Randomized trial176 participantsEnergy forIron
  6. Ferric carboxymaltose vs. oral iron in the treatment of pregnant women with iron deficiency anemia: an international, open-label, randomized controlled trial (FER-ASAP).
    Breymann C; Milman N; Mezzacasa A; Bernard R; Dudenhausen J; FER-ASAP investigators · Journal of perinatal medicine · 2018
    Randomized trial252 participantsEnergy forIron
  7. Effect of iron therapy on fatigue symptoms in non-anaemic iron deficient women of reproductive age- A Randomized Controlled Trial.
    Sultana N; Bajwa FA; Sikandar MZ; Haider MM; Majeed T · JPMA. The Journal of the Pakistan Medical Association · 2026
    Randomized trial164 participantsEnergy forIron
  8. Intravenous iron isomaltoside treatment of women suffering from severe fatigue after postpartum hemorrhage.
    Holm C; Thomsen LL; Langhoff-Roos J · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019
    Randomized trial85 participantsEnergy forIron
  9. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  10. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  11. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  12. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  13. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  14. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  15. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  16. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  17. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  18. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  19. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  20. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin