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Magnesium Plus Orange-Vanilla Flavor

Pure Essence Ionic-Fizz
4.8
★ ★ ★ ★ ★
(478 ratings)
Folate 50 mcg
Potassium 100 mg
Magnesium 300 mg
Product Image
Score75
A useful magnesium drink with active B vitamins and vitamin C. The carbonate form and small supporting ingredients keep it in the middle of the pack.
How scoring works
Quantity:6 Ounce(s) • (30 servings)
Goals:
Energy
General Health
Cardiovascular Support
Heart Health
Bone Health
Sleep Support

Score 75

A useful magnesium drink with active B vitamins and vitamin C. The carbonate form and small supporting ingredients keep it in the middle of the pack.
How scoring works

Also available as

5 options
12 servings B9 50 mcg, Magnesium 300 mg +1 more • 12 Ounce(s) • 60 servings $37.01 ($0.61 per serving) Raspberry Lemonade Flavor B9 50 mcg, Magnesium 300 mg +1 more • 12 Ounce(s) • 60 servings $40.75 ($0.67 per serving) Mixed Berry Flavor B9 50 mcg, Magnesium 300 mg +1 more • 12 Ounce(s) • 60 servings $40.58 ($0.67 per serving) Raspberry Lemonade Flavor B9 50 mcg, Magnesium 300 mg +1 more • 6 Ounce(s) • 30 servings $22.32 ($0.74 per serving) Mixed Berry Flavor B9 50 mcg, Magnesium 300 mg +1 more • 6 Ounce(s) • 30 servings $22.32 ($0.74 per serving)
$25.41($0.84 per serving)
iHerb
$ 25.41
iHerb
$ 25.41
Walmart
$ 0.00
Report prices

Analysis

Magnesium is supplied at an amount capable of making a useful daily contribution. Vitamin C, active folate, methylcobalamin, and several trace minerals make the drink broader than a plain magnesium powder.

Carbonate is not the most compelling magnesium form for absorption or digestive comfort. Potassium is modest, and bamboo, sea minerals, beet, and boron play secondary roles at the listed amounts.

The orange-vanilla flavor offers an alternative for users who want a drink rather than capsules. Its strongest fit is routine magnesium support, with only indirect relevance to sleep, stress, fitness, and heart goals.

Who is it for
  • Adults wanting flavored magnesium powder
  • People who dislike large capsules
  • Users seeking magnesium with vitamin C
Best for
  • Daily magnesium support
  • Muscle and nerve nutrition
  • Powder-based routines

Pros

  • Meaningful magnesium serving
  • Includes methylfolate and methylcobalamin
  • Simple drink preparation

Cons

  • Uses magnesium carbonate
  • Only modest potassium
  • Most extras are too small to matter much

Warnings

  • Magnesium carbonate may cause loose stools or abdominal discomfort.
  • Separate the serving from thyroid medicine and certain antibiotics.
  • People with reduced kidney function should not use concentrated magnesium without guidance.

Nutrient quality

79 High impact

A substantial magnesium amount and active folate provide a useful mineral foundation. Magnesium carbonate and several lightly dosed supporting ingredients limit absorption quality and formula depth.

Ingredient transparency

82 Highest impact

All listed actives have separate amounts and no proprietary blend hides the mineral formula. Complete mixing guidance and flavor-system ingredients are not supplied, while several botanical names lack standardization.

Customer satisfaction

74 High impact

The exceptional average rating is supported by a moderate review base. No review excerpts describe tolerance, ease of use, or repeated complaints, so those experiences remain uncertain.

Value for money

61 Moderate impact

A meaningful magnesium serving offers only moderate value in the smaller package. The weaker magnesium form and token secondary additions keep quality below the strongest mineral powders.

Report analysis

Goals

Energy
Energy
Impact
Highest effect
A- Goal FitA- Strength of SupportB CoverageB- Formula Quality
Vitamin D · 2.5 mcgMagnesium · 300 mgVitamin B12 · 30 mcgPotassium · 100 mg

A substantial magnesium amount and useful vitamin C dose provide the clearest foundational support for muscles, nerves, energy metabolism, and antioxidant defenses. Several B vitamins and trace minerals broaden the drink, although many are modestly dosed.

Most active forms and amounts are transparent, but the botanical and sea-mineral additions add little assessable depth. The 300 mg magnesium serving may cause loose stools or cramping when combined with other magnesium sources.

Study evidence
Magnesium Supportive 4 studies
General Health
General Health
Impact
High effect
A Goal FitB- Strength of SupportB CoverageB- Formula Quality
Folate · 50 mcgVitamin B12 · 30 mcgVitamin D · 2.5 mcgMagnesium · 300 mgBoron · 500 mcgZinc · 2 mgVitamin C · 250 mg

Magnesium anchors a broad mix of nutrients that may support muscle, nerve, energy, and antioxidant functions. Vitamin C is meaningful, while several other vitamins and minerals are included only in modest amounts.

Magnesium carbonate is less attractive than well-absorbed chelated forms, although active methylfolate and methylcobalamin improve the vitamin profile. The magnesium amount may cause loose stools or stomach upset in sensitive users.

Study evidence
Boron Supportive 6 studies
Folate Supportive 80 studies
Magnesium Supportive 114 studies
Vitamin C Supportive 56 studies
Cardiovascular Support
Cardiovascular Support
Impact
High effect
B+ Goal FitB Strength of SupportC CoverageB- Formula Quality
Potassium · 100 mgMagnesium · 300 mgVitamin D · 2.5 mcgVitamin B12 · 30 mcgVitamin B6 · 1 mgFolate · 50 mcgVitamin C · 250 mg

Magnesium supplies the main cardiovascular benefit through support for vascular tone, blood-pressure regulation, and normal heart rhythm. The disclosed amount is meaningful, while the folate, vitamin B6, and potassium amounts add only modest support.

The formula also includes active B-vitamin forms and antioxidant vitamin C, but magnesium carbonate is not a preferred absorbable form. Several minor minerals and botanicals add breadth without a clear cardiovascular contribution.

Study evidence
Folate Supportive 93 studies
Magnesium Supportive 123 studies
Potassium Supportive 117 studies
Vitamin B6 Supportive 35 studies
Vitamin C Supportive 101 studies
Heart Health
Heart Health
Impact
High effect
B- Goal FitB+ Strength of SupportC+ CoverageC Formula Quality
Magnesium · 300 mgVitamin B12 · 30 mcgVitamin B6 · 1 mgFolate · 50 mcgVitamin D · 2.5 mcg

Magnesium at 300 mg provides meaningful foundational cardiovascular support, while methylated B vitamins may aid homocysteine metabolism. The formula lacks a meaningful direct vascular-tone ingredient.

Magnesium carbonate is clearly disclosed, and methylcobalamin and methylfolate improve B-vitamin form quality. Numerous trace minerals and tiny botanical additions make the formula broader on the label than in functional cardiovascular depth.

Study evidence
Magnesium Supportive 158 studies
Bone Health
Bone Health
Impact
High effect
B Goal FitB- Strength of SupportC+ CoverageC Formula Quality
Magnesium · 300 mgVitamin D · 2.5 mcgCopper · 0.25 mgManganese · 1 mgBoron · 500 mcgZinc · 2 mgVitamin C · 250 mg

Magnesium provides a meaningful mineral contribution to bone formation and vitamin D function. Small amounts of vitamin D3, zinc, copper, manganese, and boron add related support but are not substantial enough to make the formula comprehensive.

The magnesium amount is useful, although magnesium carbonate is less appealing than citrate or a well-defined chelate. Many added vitamins and plant powders broaden the label more than they deepen skeletal support.

Study evidence
Boron Supportive 5 studies
Copper Disputed 20 studies
Magnesium Supportive 48 studies
Manganese Adverse 12 studies
Vitamin D Supportive 202 studies
Zinc Supportive 33 studies
Sleep Support
Sleep Support
Impact
High effect
B- Goal FitB Strength of SupportC CoverageD Formula Quality
Magnesium · 300 mg

Magnesium may support relaxation and sleep quality when intake is inadequate. The serving provides 300 mg as magnesium carbonate in a broad vitamin-and-mineral drink mix.

Magnesium carbonate is less preferred for bedtime use than glycinate, and the amount may cause digestive discomfort in sensitive users. Numerous vitamins, minerals, and botanical extras add complexity without creating another strong sleep pathway.

Study evidence
Magnesium Supportive 23 studies

Ingredients

IngredientAmount per serving
Vitamin A (Beta-Carotene)
 150 mcg
Vitamin C (Ascorbic Acid)
 250 mg
Vitamin D3
2.5 mcg
Vitamin B6 (Pyridoxine Hydrochloride)
 1 mg
Folate (L-5-Methyltetrahydrofolate)
 50 mcg
Vitamin B12 (Methylcobalamin)
 30 mcg
Magnesium (Magnesium Carbonate)
 300 mg
Zinc (Zinc Lactate)
 2 mg
Copper (Copper Gluconate)
 0.25 mg
Manganese (Manganese Gluconate)
 1 mg
Potassium (Potassium Bicarbonate)
 100 mg
Bamboo extract
60 mg
ionic Sea Minerals
10 mg
Boron (Boron Citrate)
 500 mcg
Gluten Free Adults 18–50 Vegan Dairy Free Women Vegetarian
Report overview
Folate (L-5-Methyltetrahydrofolate) · 50 mcg OverallScore65
A Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyD- Value

L-5-MTHF provides a body-ready form, while its amount is very low for general folate support. The dose disclosure is clear despite omitting explicit DFE wording, and adequate B12 supports masking-risk safeguards. Cost efficiency is weak relative to the form or active amount supplied.

View ingredientView products
Potassium (Potassium Bicarbonate) · 100 mg OverallScore64
A+ Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyF Value

Potassium bicarbonate provides a high-quality alkalizing source in an easy-to-mix powder. The amount is still a low retail dose and the label does not separate compound weight from elemental yield. A high serving cost limits potassium-specific value.

View ingredientView products
Magnesium (Magnesium Carbonate) · 300 mg OverallScore50
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

Uses low-bioavailability magnesium carbonate at a therapeutic elemental amount. Vitamin B6, vitamin D, or boron adds relevant formulation support. High cost and a primary oxide or carbonate source weaken value.

View ingredientView products
Loading alternative details
82 Performance

MagSoothe Tart Raspberry Lemonade Flavor

Jigsaw Health
<p>Magnesium lysinate glycinate offers a more favorable form than magnesium carbonate, while potassium bicarbonate preserves useful electrolyte coverage in a simpler formula. Magnesium is lower and folate is absent, but the ingredient list is easier to assess.</p>
79 Performance

Target-Mins Magnesium Potassium Aspartate

Country Life
<p>Several organic magnesium and potassium forms broaden mineral coverage and raise the listed amounts. Magnesium oxide and apparently repeated totals reduce confidence, while folate, methylcobalamin, and the original’s wider vitamin profile are omitted.</p>
72 Performance

Super D-K Calcium Plus Raspberry Lemonade Flavor

Pure Essence Ionic-Fizz
<p>Calcium, magnesium, vitamin D3, vitamin K2, methylfolate, potassium, and boron create broader bone-oriented coverage. Magnesium remains carbonate and the drink base is incompletely disclosed, but the mineral-and-vitamin combination is more coherent for bone support.</p>
80 Budget

Target-Mins Magnesium Potassium Aspartate With Other Target-Mins Chelates

Country Life
<p>A lower-cost formula provides magnesium and potassium across several listed forms, including citrate and taurinate. The repeated full amounts make the true totals unclear, magnesium oxide lowers form quality, and folate plus the broader vitamin profile are absent.</p>
79 Budget

MagSRT

Jigsaw Health
<p>Magnesium malate, active P-5-P, methylfolate, and methylcobalamin provide better form quality and a more meaningful folate amount. The large magnesium amount may upset sensitive stomachs, and the serving cost is not lower for the least expensive original variants.</p>
79 Budget

Magnesium Plus Mixed Berry Flavor

Pure Essence Ionic-Fizz
<p>The same magnesium carbonate, potassium bicarbonate, methylfolate, methylcobalamin, vitamins, and trace minerals preserve the closest ingredient match with better serving value. Core limitations are unchanged, including the less favorable magnesium form and several token additions.</p>
81 Value

MagSoothe Tart Raspberry Lemonade Flavor

Jigsaw Health
<p>Magnesium lysinate glycinate and potassium bicarbonate provide stronger mineral forms in a concise drink mix. The serving value is weaker than the original variants, and lower magnesium plus no folate make it a quality trade rather than an economy upgrade.</p>
66 Value

Calcium Plus Raspberry Lemonade Flavor

Pure Essence Ionic-Fizz
<p>A lower-cost serving keeps the original’s magnesium, potassium, methylfolate, methylcobalamin, vitamins, and trace minerals while adding a calcium entry. The supplied calcium amount appears implausibly low, so its added bone-support value cannot be trusted without label verification.</p>
71 Value

Pink 1000 mg Vitamin C Pink Lemonade

Emergen-C
<p>A low-cost drink mix adds far more vitamin C and more listed potassium while retaining small amounts of folate and magnesium. Basic mineral forms, notable carbohydrates, and duplicated entries make it a weaker fit for magnesium, sleep, and stress goals.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Magnesium Citrate, Magnesium Oxide, and Magnesium Sulfate Supplementation on Arterial Stiffness: A Randomized, Double-Blind, Placebo-Controlled Intervention Trial.
    Schutten JC; Joris PJ; Groendijk I; Eelderink C; Groothof D; van der Veen Y; Westerhuis R; Goorman F; Danel RM; de Borst MH; Bakker SJL · Journal of the American Heart Association · 2022
    Randomized trial164 participantsHeart Health forMagnesium
  2. Effects of zinc and magnesium supplements on postpartum depression and anxiety: A randomized controlled clinical trial.
    Fard FE; Mirghafourvand M; Mohammad-Alizadeh Charandabi S; Farshbaf-Khalili A; Javadzadeh Y; Asgharian H · Women & health · 2017
    Randomized trial99 participantsStress Relief forMagnesium
  3. The effect of magnesium supplementation on muscle fitness: a meta-analysis and systematic review.
    Wang R; Chen C; Liu W; Zhou T; Xun P; He K; Chen P · Magnesium research · 2018
    Meta-analysis542 participants14 studies pooledFitness forMagnesium
  4. Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep.
    Nielsen FH; Johnson LK; Zeng H · Magnesium research · 2011
    Randomized trial100 participantsSleep Support forMagnesium
  5. Magnesium Disorders and Prognosis in Heart Failure: A Systematic Review.
    Voultsos P; Bazmpani MA; Papanastasiou CA; Papadopoulos CE; Efthimiadis G; Karvounis H; Kalogeropoulos AP; Karamitsos TD · Cardiology in review · 2022
    Systematic review13,539 participants8 studies pooledHeart Health forMagnesium
  6. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review.
    Rawji A; Peltier MR; Mourtzanakis K; Awan S; Rana J; Pothen NJ; Afzal S · Cureus · 2024
    Systematic review15 studies pooledStress Relief forMagnesium
  7. The Role of Magnesium in Sleep Health: a Systematic Review of Available Literature.
    Arab A; Rafie N; Amani R; Shirani F · Biological trace element research · 2023
    Systematic review7,582 participants9 studies pooledSleep Support forMagnesium
  8. Magnesium status and the physical performance of volleyball players: effects of magnesium supplementation.
    Setaro L; Santos-Silva PR; Nakano EY; Sales CH; Nunes N; Greve JM; Colli C · Journal of sports sciences · 2014
    Randomized trial25 participantsFitness forMagnesium
  9. Low serum magnesium and cardiovascular mortality in chronic heart failure: a propensity-matched study.
    Adamopoulos C; Pitt B; Sui X; Love TE; Zannad F; Ahmed A · International journal of cardiology · 2009
    Cohort study1,569 participantsHeart Health forMagnesium
  10. Short-Term Magnesium Supplementation Has Modest Detrimental Effects on Cycle Ergometer Exercise Performance and Skeletal Muscle Mitochondria and Negligible Effects on the Gut Microbiota: A Randomized Crossover Clinical Trial.
    Bomar MC; Ewell TR; Brown RL; Brown DM; Kwarteng BS; Abbotts KSS; Butterklee HM; Williams NNB; Wrigley SD; Walsh MA; Hamilton KL; Thomson DP; Weir TL; Bell C · Nutrients · 2025
    Randomized trial15 participantsFitness forMagnesium
  11. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  12. Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
    Khalid S; Bashir S; Mehboob R; Anwar T; Ali M; Hashim M; Waseem H; Basharat S · Frontiers in endocrinology · 2024
    Randomized trial320 participantsSleep Support forMagnesium
  13. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledHeart Health Cardiovascular Support forMagnesium
  14. The effects of magnesium supplementation on exercise performance.
    Finstad EW; Newhouse IJ; Lukaski HC; Mcauliffe JE; Stewart CR · Medicine and science in sports and exercise · 2001
    Randomized trial32 participantsFitness forMagnesium
  15. Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study.
    Zhang Y; Chen C; Lu L; Knutson KL; Carnethon MR; Fly AD; Luo J; Haas DM; Shikany JM; Kahe K · Sleep · 2022
    Cohort study3,964 participantsSleep Support forMagnesium
  16. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  17. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  18. Lidocaine vs. magnesium: effect on analgesia after a laparoscopic cholecystectomy.
    Saadawy IM; Kaki AM; Abd El Latif AA; Abd-Elmaksoud AM; Tolba OM · Acta anaesthesiologica Scandinavica · 2010
    Randomized trial120 participantsSleep Support forMagnesium
  19. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium Stress Relief forVitamin B6
  20. Prospective association between dietary magnesium intake and physical performance in older women and men.
    Arias-Fernández L; Struijk EA; Caballero FF; Ortolá R; García-Esquinas E; Rodríguez-Artalejo F; Lopez-Garcia E; Lana A · European journal of nutrition · 2022
    Cohort study863 participantsFitness forMagnesium
  21. Magnesium Levels in Drinking Water and Coronary Heart Disease Mortality Risk: A Meta-Analysis.
    Jiang L; He P; Chen J; Liu Y; Liu D; Qin G; Tan N · Nutrients · 2016
    Meta-analysis77,821 participants10 studies pooledHeart Health forMagnesium
  22. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
    Abbasi B; Kimiagar M; Sadeghniiat K; Shirazi MM; Hedayati M; Rashidkhani B · Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013
    Randomized trial46 participantsSleep Support forMagnesium
  23. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsFitness Energy forMagnesium
  24. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  25. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  26. Magnesium supplements, sleep quality, and nocturnal leg cramps: a combination of cross-sectional and prospective studies.
    Stadie N; Heinzer R; Marques-Vidal P · European journal of nutrition · 2026
    Cohort study3,887 participantsSleep Support forMagnesium
  27. No Effect of Topical Application of a Commercial Magnesium Gel on Exercise Recovery in Active Individuals.
    Coates AM; Patel DV; Binet ER; Gibala MJ · International journal of sport nutrition and exercise metabolism · 2025
    Randomized trial35 participantsFitness forMagnesium
  28. Effects of Combined Intravenous and Topical Magnesium Sulfate Administration on Pain, Stress, and Functional Recovery After Total Knee Arthroplasty: A Prospective, Randomized, Blinded Controlled Trial.
    Wang Q; Wang Y; Hu J; Chen C; Yang J; Kang P · Drug design, development and therapy · 2026
    Randomized trial150 participantsStress Relief forMagnesium
  29. Long-term magnesium supplementation improves arterial stiffness in overweight and obese adults: results of a randomized, double-blind, placebo-controlled intervention trial.
    Joris PJ; Plat J; Bakker SJ; Mensink RP · The American journal of clinical nutrition · 2017
    Randomized trial52 participantsHeart Health forMagnesium
  30. A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
    Barna O; Lohoida P; Holovchenko Y; Bazylevych A; Velychko V; Hovbakh I; Bula L; Shechter M · Nutrition journal · 2021
    Randomized trial175 participantsSleep Support forMagnesium
  31. Minerals and Sarcopenia in Older Adults: An Updated Systematic Review.
    van Dronkelaar C; Fultinga M; Hummel M; Kruizenga H; Weijs PJM; Tieland M · Journal of the American Medical Directors Association · 2023
    Systematic review45 studies pooledFitness forMagnesium
  32. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  33. Effect of magnesium supplementation on endothelial function: A systematic review and meta-analysis of randomized controlled trials.
    Darooghegi Mofrad M; Djafarian K; Mozaffari H; Shab-Bidar S · Atherosclerosis · 2019
    Meta-analysis306 participants7 studies pooledHeart Health forMagnesium
  34. The effects of magnesium L-threonate (Magtein®) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial.
    Lopresti AL; Smith SJ · Frontiers in nutrition · 2026
    Randomized trial100 participantsSleep Support forMagnesium
  35. The effects of magnesium supplementation on exercise performance.
    Newhouse IJ; Finstad EW · Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine · 2000
    Systematic review12 studies pooledFitness forMagnesium
  36. The association between dietary intake of magnesium and psychiatric disorders among Iranian adults: a cross-sectional study.
    Anjom-Shoae J; Sadeghi O; Hassanzadeh Keshteli A; Afshar H; Esmaillzadeh A; Adibi P · The British journal of nutrition · 2019
    Cross-sectional study3,172 participantsStress Relief forMagnesium
  37. Effects of long-term magnesium supplementation on endothelial function and cardiometabolic risk markers: A randomized controlled trial in overweight/obese adults.
    Joris PJ; Plat J; Bakker SJ; Mensink RP · Scientific reports · 2018
    Randomized trial52 participantsHeart Health forMagnesium
  38. Diabetes modifies the association between magnesium and insomnia, but not depressive symptomatology, in Puerto Rican adults: a prospective cohort study.
    Chen F; Mangano KM; Scott TM; Li W; Falcón LM; Gao X; Garelnabi M; Tucker KL · The American journal of clinical nutrition · 2026
    Cohort study613 participantsSleep Support forMagnesium
  39. Does magnesium supplementation improve body composition and muscle strength in middle-aged overweight women? A double-blind, placebo-controlled, randomized clinical trial.
    Moslehi N; Vafa M; Sarrafzadeh J; Rahimi-Foroushani A · Biological trace element research · 2013
    Randomized trial74 participantsFitness forMagnesium
  40. Blood Magnesium Level and Selected Oxidative Stress Indices in Lead-Exposed Workers.
    Wyparło-Wszelaki M; Wąsik M; Machoń-Grecka A; Kasperczyk A; Bellanti F; Kasperczyk S; Dobrakowski M · Biological trace element research · 2021
    Cross-sectional study232 participantsStress Relief forMagnesium
  41. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  42. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  43. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  44. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  45. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  46. The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
    Ju Y; Xiong W; Pang Y; Chen Z; Hou J; Zheng S; Li Z; Liu T; Xia H; Xia M; Zhong Y; Li J; Jiang X · Biological trace element research · 2026
    Scoping review18 studies pooledBone Health forCopper
  47. Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
    Chen M; Jia L; Gao R · Frontiers in nutrition · 2024
    Cohort study5,286 participantsBone Health forCopper
  48. Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
    Hu M; Wang Z; Li C; Zheng Y; Hu J · Medicine · 2025
    Cross-sectional studyBone Health forCopper
  49. The association between dietary mineral intake and bone mineral density: a cross-sectional study.
    Wei M; Wei J; Huang S · Journal of health, population, and nutrition · 2025
    Cross-sectional study11,520 participantsBone Health forCopper
  50. Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
    Cui A; Yan J; Li H; Fan Z; Wei X; Wang H; Zhuang Y · PloS one · 2024
    Cross-sectional study6,965 participantsBone Health forCopper
  51. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  52. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  53. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  54. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  55. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  56. Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES.
    Ling R; Ai Y; Chen C; Zhang J; Zou Z; Cheng S; Li C; Li X; Wang B · Metabolites · 2023
    Cross-sectional study2,640 participantsBone Health forManganese
  57. The Manganese-Bone Connection: Investigating the Role of Manganese in Bone Health.
    Taskozhina G; Batyrova G; Umarova G; Issanguzhina Z; Kereyeva N · Journal of clinical medicine · 2024
    Narrative reviewBone Health forManganese
  58. Associations of multiple metals with bone mineral density: A population-based study in US adults.
    Wei MH; Cui Y; Zhou HL; Song WJ; Di DS; Zhang RY; Huang Q; Liu JA; Wang Q · Chemosphere · 2021
    Cross-sectional studyBone Health forManganese
  59. Sex-specific associations of urinary mixed-metal concentrations with femoral bone mineral density among older people: an NHANES (2017-2020) analysis.
    Li H; Li G; Yi M; Zhou J; Deng Y; Huang Y; He S; Meng X; Liu L · Frontiers in public health · 2024
    Cross-sectional study31 participantsBone Health forManganese
  60. Relationship between blood manganese and bone mineral density and bone mineral content in adults: A population-based cross-sectional study.
    Wang C; Zhu Y; Long H; Ou M; Zhao S · PloS one · 2022
    Cross-sectional study9,732 participantsBone Health forManganese
  61. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  62. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  63. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  64. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  65. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  66. Increased incidence of fractures in middle-aged and elderly men with low intakes of phosphorus and zinc.
    Elmståhl S; Gullberg B; Janzon L; Johnell O; Elmståhl B · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 1999
    Cohort study6,576 participantsBone Health forZinc
  67. Zinc Supplementation Increases Procollagen Type 1 Amino-Terminal Propeptide in Premenarcheal Girls: A Randomized Controlled Trial.
    Berger PK; Pollock NK; Laing EM; Chertin V; Bernard PJ; Grider A; Shapses SA; Ding KH; Isales CM; Lewis RD · The Journal of nutrition · 2016
    Randomized trial147 participantsBone Health forZinc
  68. Randomized controlled trial of prenatal zinc supplementation and fetal bone growth.
    Merialdi M; Caulfield LE; Zavaleta N; Figueroa A; Costigan KA; Dominici F; Dipietro JA · The American journal of clinical nutrition · 2004
    Randomized trial242 participantsBone Health forZinc
  69. The effects of zinc supplementation on serum zinc, alkaline phosphatase activity and fracture healing of bones.
    Sadighi A; Roshan MM; Moradi A; Ostadrahimi A · Saudi medical journal · 2009
    Randomized trial60 participantsBone Health forZinc
  70. Is Zinc an Important Trace Element on Bone-Related Diseases and Complications? A Meta-analysis and Systematic Review from Serum Level, Dietary Intake, and Supplementation Aspects.
    Ceylan MN; Akdas S; Yazihan N · Biological trace element research · 2021
    Meta-analysis40 studies pooledBone Health forZinc
  71. Associations of dietary folate, vitamin B6 and B12 intake with cardiovascular outcomes in 115664 participants: a large UK population-based cohort.
    Zhang B; Dong H; Xu Y; Xu D; Sun H; Han L · European journal of clinical nutrition · 2023
    Cohort study115,664 participantsCardiovascular Support forFolate
  72. Folate, Homocysteine, and Adverse Outcomes After Ischemic Stroke.
    Shi M; Zheng J; Liu Y; Mao X; Wu X; Chu M; Niu H; Sun L; Chang X; He Y; Liu Y; Guo D; Zhang Y; Zhu Z; Zhao J · Journal of the American Heart Association · 2024
    Cohort study3,530 participantsCardiovascular Support forFolate
  73. Effect of folic acid on endothelial function following acute myocardial infarction.
    Moens AL; Claeys MJ; Wuyts FL; Goovaerts I; Van Hertbruggen E; Wendelen LC; Van Hoof VO; Vrints CJ · The American journal of cardiology · 2007
    Randomized trial40 participantsCardiovascular Support forFolate
  74. Folic acid enhances endothelial function and reduces blood pressure in smokers: a randomized controlled trial.
    Mangoni AA; Sherwood RA; Swift CG; Jackson SH · Journal of internal medicine · 2003
    Randomized trial24 participantsCardiovascular Support forFolate
  75. 5-methyltetrahydrofolate, the active form of folic acid, restores endothelial function in familial hypercholesterolemia.
    Verhaar MC; Wever RM; Kastelein JJ; van Dam T; Koomans HA; Rabelink TJ · Circulation · 1998
    Non-randomized trial20 participantsCardiovascular Support forFolate
  76. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  77. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  78. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  79. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  80. Sex-specific associations between sodium and potassium intake and overall and cause-specific mortality: a large prospective U.S. cohort study, systematic review, and updated meta-analysis of cohort studies.
    Gan L; Zhao B; Inoue-Choi M; Liao LM; Graubard BI; Weinstein SJ; Albanes D; Huang J · BMC medicine · 2024
    Meta-analysis416,104 participantsCardiovascular Support forPotassium
  81. Potassium intake, stroke, and cardiovascular disease a meta-analysis of prospective studies.
    D'Elia L; Barba G; Cappuccio FP; Strazzullo P · Journal of the American College of Cardiology · 2011
    Meta-analysis247,510 participants11 studies pooledCardiovascular Support forPotassium
  82. Blood pressure response to changes in sodium and potassium intake: a metaregression analysis of randomised trials.
    Geleijnse JM; Kok FJ; Grobbee DE · Journal of human hypertension · 2003
    Meta-analysis27 studies pooledCardiovascular Support forPotassium
  83. Twenty-Four-Hour Urinary Sodium and Potassium Excretion and Their Associations With Blood Pressure Among Adults in China: Baseline Survey of Action on Salt China.
    Li Y; Zhang P; Wu J; Ma J; Xu J; Zhang X; Luo R; Liu M; Sun Y; Li X; Tan M; He FJ; MacGregor GA; Li X · Hypertension (Dallas, Tex. : 1979) · 2021
    Cross-sectional study5,353 participantsCardiovascular Support forPotassium
  84. Dietary Sodium and Potassium Intake and Risk of Non-Fatal Cardiovascular Diseases: The Million Veteran Program.
    Wang DD; Li Y; Nguyen XT; Song RJ; Ho YL; Hu FB; Willett WC; Wilson PWF; Cho K; Gaziano JM; Djoussé L; On Behalf Of The Va Million Veteran Program · Nutrients · 2022
    Cohort study180,156 participantsCardiovascular Support forPotassium
  85. Association between serum pyridoxal 5'-phosphate levels and all-cause, cardiovascular mortality, and cardiovascular disease in adults: a population-based cohort study.
    Xuan C; Liu RH; Zhao C; Li J; Zhou TT; Tian QW; He GW · Therapeutic advances in chronic disease · 2024
    Cohort studyCardiovascular Support forVitamin B6
  86. Folate and vitamin B6 rapidly normalize endothelial dysfunction in children with type 1 diabetes mellitus.
    MacKenzie KE; Wiltshire EJ; Gent R; Hirte C; Piotto L; Couper JJ · Pediatrics · 2006
    Randomized trial124 participantsCardiovascular Support forVitamin B6
  87. Pyridoxine improves endothelial function in cardiac transplant recipients.
    Miner SE; Cole DE; Evrovski J; Forrest Q; Hutchison S; Holmes K; Ross HJ · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2001
    Randomized trial31 participantsCardiovascular Support forVitamin B6
  88. Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women.
    Rimm EB; Willett WC; Hu FB; Sampson L; Colditz GA; Manson JE; Hennekens C; Stampfer MJ · JAMA · 1998
    Cohort study80,082 participantsCardiovascular Support forVitamin B6
  89. Efficacy and safety of pyridoxal 5'-phosphate (MC-1) in high-risk patients undergoing coronary artery bypass graft surgery: the MEND-CABG II randomized clinical trial.
    MEND-CABG II Investigators; Alexander JH; Emery RW; Carrier M; Ellis SJ; Mehta RH; Hasselblad V; Menasche P; Khalil A; Cote R; Bennett-Guerrero E; Mack MJ; Schuler G; Harrington RA; Tardif JC · JAMA · 2008
    Randomized trial3,023 participantsCardiovascular Support forVitamin B6
  90. Vitamin C may reduce troponin and CKMB levels after PCI and CABG: a meta-analysis.
    Rozemeijer S; Hemilä H; van Baaren M; de Man AME · BMC cardiovascular disorders · 2023
    Meta-analysis872 participants7 studies pooledCardiovascular Support forVitamin C
  91. Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension.
    Taddei S; Virdis A; Ghiadoni L; Magagna A; Salvetti A · Circulation · 1998
    Clinical trial49 participantsCardiovascular Support forVitamin C
  92. Vitamin C supplementation improves blood pressure and oxidative stress after acute exercise in patients with poorly controlled type 2 diabetes mellitus: A randomized, placebo-controlled, cross-over study.
    Boonthongkaew C; Tong-Un T; Kanpetta Y; Chaungchot N; Leelayuwat C; Leelayuwat N · The Chinese journal of physiology · 2021
    Randomized trial24 participantsCardiovascular Support forVitamin C
  93. Vascular benefits of vitamin C supplementation against fine particulate air pollution in healthy adults: A double-blind randomised crossover trial.
    Ren J; Liang J; Wang J; Yin B; Zhang F; Li X; Zhu S; Tian H; Cui Q; Song J; Liu G; Ling W; Ma Y · Ecotoxicology and environmental safety · 2022
    Randomized trial58 participantsCardiovascular Support forVitamin C
  94. Ascorbic acid reduces blood pressure and arterial stiffness in type 2 diabetes.
    Mullan BA; Young IS; Fee H; McCance DR · Hypertension (Dallas, Tex. : 1979) · 2003
    Randomized trial30 participantsCardiovascular Support forVitamin C
  95. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  96. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  97. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  98. Dietary Magnesium May Be Protective for Aging of Bone and Skeletal Muscle in Middle and Younger Older Age Men and Women: Cross-Sectional Findings from the UK Biobank Cohort.
    Welch AA; Skinner J; Hickson M · Nutrients · 2018
    Cross-sectional study156,575 participantsFitness forMagnesium
  99. Dietary Magnesium Is Positively Associated With Skeletal Muscle Power and Indices of Muscle Mass and May Attenuate the Association Between Circulating C-Reactive Protein and Muscle Mass in Women.
    Welch AA; Kelaiditi E; Jennings A; Steves CJ; Spector TD; MacGregor A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016
    Cross-sectional study2,570 participantsFitness forMagnesium
  100. Nutritional intake as a determinant of high-speed resistance and multicomponent training efficacy on strength in older women at risk of sarcopenia. A randomized clinical trial.
    Polo-Ferrero L; Recio-Rodriguez JI; González-Manzano S; Martín-Vallejo J; Barbero-Iglesias FJ; Montero-Errasquín B; Cruz-Jentoft AJ; Méndez-Sánchez R · Clinical nutrition (Edinburgh, Scotland) · 2025
    Randomized trial80 participantsFitness forMagnesium
  101. Longitudinal Association Between Sodium and Potassium Intake and Physical Performance in Older Adults.
    Lana A; Struijk EA; Ortolá R; Rodríguez-Artalejo F; Lopez-Garcia E · The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
    Cohort study868 participantsFitness forPotassium
  102. Exercise-induced hyperkalaemia can be reduced in human subjects by moderate training without change in skeletal muscle Na,K-ATPase concentration.
    Kjeldsen K; Nørgaard A; Hau C · European journal of clinical investigation · 1991
    Observational study15 participantsFitness forPotassium
  103. Potassium Nitrate in Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial.
    Zamani P; Shah SJ; Cohen JB; Zhao M; Yang W; Afable JL; Caturla M; Maynard H; Pourmussa B; Demastus C; Mohanty I; Miyake MM; Adusumalli S; Margulies KB; Prenner SB; Poole DC; Wilson N; Reddy R; Townsend RR; Ischiropoulos H; Cappola TP; Chirinos JA · JAMA cardiology · 2025
    Randomized trial84 participantsFitness forPotassium
  104. Potassium Bicarbonate Supplementation Lowers Bone Turnover and Calcium Excretion in Older Men and Women: A Randomized Dose-Finding Trial.
    Dawson-Hughes B; Harris SS; Palermo NJ; Gilhooly CH; Shea MK; Fielding RA; Ceglia L · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016
    Randomized trial244 participantsFitness forPotassium
  105. Exercise-Associated Muscle Cramps in Ironman-Distance Triathletes Over 3 Decades.
    Nilssen PK; Johnson KB; Hiller WDB; Miller TK; Connolly CP · Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine · 2026
    Observational study10,533 participantsFitness forPotassium
  106. Effects of boron supplementation on the severity and duration of pain in primary dysmenorrhea.
    Nikkhah S; Dolatian M; Naghii MR; Zaeri F; Taheri SM · Complementary therapies in clinical practice · 2015
    Randomized trial113 participantsGeneral Health forBoron
  107. Efficacy and safety of tavaborole topical solution, 5%, a novel boron-based antifungal agent, for the treatment of toenail onychomycosis: Results from 2 randomized phase-III studies.
    Elewski BE; Aly R; Baldwin SL; González Soto RF; Rich P; Weisfeld M; Wiltz H; Zane LT; Pollak R · Journal of the American Academy of Dermatology · 2015
    Randomized trialGeneral Health forBoron
  108. The efficacy and safety of tavaborole, a novel, boron-based pharmaceutical agent: phase 2 studies conducted for the topical treatment of toenail onychomycosis.
    Toledo-Bahena ME; Bucko A; Ocampo-Candiani J; Herz-Ruelas ME; Jones TM; Jarratt MT; Pollak RA; Zane LT · Journal of drugs in dermatology : JDD · 2015
    Clinical trial336 participantsGeneral Health forBoron
  109. Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA).
    Henriksson R; Capala J; Michanek A; Lindahl SA; Salford LG; Franzén L; Blomquist E; Westlin JE; Bergenheim AT; Swedish Brain Tumour Study Group · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2009
    Single-arm trial30 participantsGeneral Health forBoron
  110. Effects of Calcium Fructoborate on Levels of C-Reactive Protein, Total Cholesterol, Low-Density Lipoprotein, Triglycerides, IL-1β, IL-6, and MCP-1: a Double-blind, Placebo-controlled Clinical Study
    Otilia-Constantina Rogoveanu, George Dan Mogosanu, Cornelia Bejenaru, Ludovic Everard Bejenaru, Octavian Croitoru, Johny Neamtu, Zbigniew Pietrzkowski, Tania Reyes-Izquierdo, Andrei Bita, Iulia Daria Scorei, Romulus Ion Scorei · Biological Trace Element Research · 2015
    Randomized trial78 participantsGeneral Health forBoron
  111. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsGeneral Health forFolate
  112. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsGeneral Health forFolate
  113. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsGeneral Health forFolate
  114. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewGeneral Health forFolate
  115. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledGeneral Health forFolate
  116. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  117. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  118. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  119. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  120. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  121. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  122. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  123. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  124. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  125. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  126. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  127. Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
    Khodadad M; Bahadoran P; Kheirabadi GR; Sabzghabaee AM · International journal of preventive medicine · 2022
    Randomized trial81 participantsStress Relief forVitamin B6
  128. RENAL PROTECTIVE EFFECT AND CLINICAL ANALYSIS OF VITAMIN B 6 IN PATIENTS WITH SEPSIS.
    Wang Y; Lu WL; Feng WM; Xu W; Liu LH; He LM · Shock (Augusta, Ga.) · 2024
    Randomized trial128 participantsStress Relief forVitamin B6
  129. Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial.
    Pouteau E; Kabir-Ahmadi M; Noah L; Mazur A; Dye L; Hellhammer J; Pickering G; Dubray C · PloS one · 2019
    Randomized trial264 participantsStress Relief forVitamin B6
  130. Associations between dietary intake of B-vitamins and psychological disorders among Iranian women: a cross-sectional study.
    Mozaffari H; Darooghegi Mofrad M; Surkan PJ; Askari M; Azadbakht L · Public health nutrition · 2021
    Cross-sectional study447 participantsStress Relief forVitamin B6