One 'n' Only

One 'n' Only

Pure Essence4.7 (256 ratings)
Format:Tablet Quantity: 60 Tablet(s) · 60 servings
Goals
$45.10 $0.75 per serving

Product analysis

51 out of 100

One 'n' Only may help fill nutrient gaps that matter for normal immune function, blood formation and bone health. Undisclosed blend contents make the added ingredients harder to judge.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality62

Several B vitamins and minerals have well-identified, favorable forms. Kelp-derived iodine is less precisely identified, and unknown blend contents limit a full quality judgment.

Ingredient Transparency75

All ingredient amounts and most forms are listed. Blend contents and the proportions of mixed forms are not disclosed, limiting detailed comparison.

Value For Money34

Several nutrients are relatively costly at the serving price, even though B6 offers fairer value. Reliable comparisons are unavailable for much of the remaining formula.

Customer Satisfaction74

Customer ratings are very positive across hundreds of reviews. They describe satisfaction without proving broad health benefits.

Product Focus0

The clearest role is filling nutrient gaps relevant to immunity, blood formation and normal energy use. Small calcium and magnesium amounts offer limited support for bone-focused use, and extra benefits remain uncertain when nutritional needs are met.

Format
Tablet
Container
60 Tablet(s)
Per serving
$0.75
Customer rating
4.7 · 256 ratings
Report analysis

Goals

Immunity
Impact
Highest effect
C Ingredient FitA+ PathwaysA+ EvidenceA+ Formulation Logic
Magnesium · 25 mgVitamin C · 240 mgZinc · 15 mgVitamin A · 6000 mcgVitamin D · 25 mcgSelenium · 100 mcg
Study evidence
Magnesium Supportive 8 studies
Selenium Mixed 37 studies
Vitamin A Supportive 107 studies
Vitamin C Supportive 53 studies
Vitamin D Supportive 85 studies
Vitamin E Supportive 21 studies
Zinc Supportive 73 studies
Impact
Highest effect
B Ingredient FitA+ PathwaysB+ EvidenceA+ Formulation Logic
Folate · 400 mcgVitamin B12 · 100 mcgVitamin D · 25 mcgMagnesium · 25 mgVitamin K · 20 mcgSelenium · 100 mcgZinc · 15 mgVitamin C · 240 mg
Study evidence
Folate Supportive 80 studies
Magnesium Supportive 114 studies
Selenium Supportive 70 studies
Vitamin C Supportive 56 studies
Vitamin D Supportive 115 studies
Vitamin K Supportive 34 studies
Zinc Supportive 60 studies
Impact
High effect
C+ Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 100 mcgNiacin · 25 mgVitamin B12 · 100 mcgRiboflavin · 25.5 mgThiamin · 22.5 mgVitamin B5 · 30 mgVitamin B6 · 30 mgVitamin D · 25 mcgZinc · 15 mgMagnesium · 25 mg
Study evidence
Biotin Supportive 5 studies
Chromium Supportive 47 studies
Iodine Mixed 17 studies
Magnesium Supportive 61 studies
Niacin Supportive 17 studies
Selenium Mixed 28 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies
Vitamin D Supportive 65 studies
Zinc Supportive 12 studies
Skin Health
Impact
High effect
C- Ingredient FitB- PathwaysA+ EvidenceA+ Formulation Logic
Zinc · 15 mgVitamin C · 240 mgCopper · 1 mgSelenium · 100 mcgVitamin E · 83 mg
Study evidence
Biotin Supportive 10 studies
Copper Supportive 16 studies
Niacin Supportive 61 studies
Selenium Supportive 22 studies
Vitamin A Supportive 106 studies
Vitamin C Supportive 53 studies
Vitamin E Supportive 38 studies
Zinc Supportive 66 studies
Impact
Lower effect
D+ Ingredient FitB+ PathwaysA+ EvidenceA+ Formulation Logic
Folate · 400 mcgVitamin B12 · 100 mcgVitamin B6 · 30 mgMolybdenum · 30 mcgSelenium · 100 mcgMagnesium · 25 mgVitamin E · 83 mgZinc · 15 mgVitamin C · 240 mgCholine · 50 mgRiboflavin · 25.5 mg
Study evidence
Choline Supportive 6 studies
Folate Supportive 16 studies
Magnesium Supportive 19 studies
Selenium Supportive 10 studies
Vitamin C Supportive 9 studies
Vitamin E Supportive 23 studies
Zinc Supportive 30 studies
Impact
Moderate effect
C Ingredient FitF PathwaysA EvidenceA+ Formulation Logic
Iodine · 150 mcgVitamin D · 25 mcgVitamin B5 · 30 mgMagnesium · 25 mgRiboflavin · 25.5 mgThiamin · 22.5 mgVitamin B12 · 100 mcgPotassium · 5 mg
Study evidence
Iodine Adverse 3 studies
Magnesium Supportive 4 studies
Potassium Supportive 2 studies
Thiamin Disputed 12 studies
Vitamin D Supportive 32 studies

Ingredients

IngredientAmount per servingScore
Vitamin A (Beta-Carotene)
6000 mcg
Vitamin C (Calcium Ascorbate)
240 mg
Vitamin D3
25 mcg
Vitamin E (D-Alpha-Tocopheryl Succinate)
83 mg
Vitamin K2 (Menaquinone-7)
20 mcg
Thiamine (Thiamine Mononitrate)
22.5 mg 65
Riboflavin
25.5 mg 49
Niacin (Niacinamide)
25 mg 65
Vitamin B6 (Pyridoxine Hydrochloride)
30 mg 75
Folate (L-5-Methyltetrahydrofolate)
400 mcg 84
Vitamin B12 (Methylcobalamin)
100 mcg 59
Biotin (D-Biotin)
100 mcg
Pantothenic Acid (D-Calcium Pantothenate)
30 mg 61
Choline (Choline Bitartrate)
50 mg 55
Calcium (Calcium Ascorbate, Calcium Pantothenate)
32 mg
Iodine (North Atlantic Kelp)
150 mcg 74
Magnesium (Magnesium Citrate, Magnesium Oxide)
25 mg
Zinc (Zinc Lactate)
15 mg 74
Selenium (Selenium L-Methyl Selenocysteine)
100 mcg 77
Copper (Copper Sebacate)
1 mg 72
Manganese (Manganese Citrate)
2.5 mg 70
Chromium (Chromium Polynicotinate)
100 mcg 47
Molybdenum (Molybdenum Glycinate)
30 mcg 70
Potassium (Potassium Citrate)
5 mg
SuperFood Complex
387.5 mg
Herbal Extracts
220 mg
Co-Nutrients
35 mg
Bioflavonoids
50 mg
Minerals
26 mg
Digestive Aids/Enzymes
10 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
C Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value
A serving supplies 150 mcg of iodine at a higher cost per serving. That amount fits daily maintenance. The chemical form of iodine is unknown.
How this ingredient is rated

Active Ingredient Quality & Bioavailability61

The chemical form of iodine is unknown. The marine source has an organic or geographic sourcing marker, although the specific detail is unavailable here.
Iodine Form & Bioavailability
The chemical form of iodine is unknown.
Marine Source Purity & Sourcing
The marine source has an organic or geographic sourcing marker, although the specific detail is unavailable here.

Dose, Safety & Label Transparency100

The label states 150 mcg of iodine per serving. That amount supports daily maintenance and is below the adult upper limit.
Dosage Efficacy for Daily Support
The 150 mcg serving falls within the range for daily thyroid maintenance.
Dosage Safety & Upper Limits
The 150 mcg serving is below the adult upper intake limit.
Elemental Iodine Transparency
The label states the iodine amount as 150 mcg per serving.

Value50

The cost per labeled serving is higher.
Price Per Effective Serving
The cost per labeled serving is higher.
A+ Ingredient Form & Label QualityC- Dose, Safety & Label TransparencyC Value
Each serving provides 30 mg per serving of vitamin B6 at a moderate cost per mg. That serving exceeds the European adult daily upper limit of 12 mg. The B6 comes from pyridoxine hydrochloride.
How this ingredient is rated

Ingredient Form & Label Quality100

The B6 source is pyridoxine hydrochloride. No artificial dyes, titanium dioxide or talc are reported.
Vitamin B6 Form Identification
The B6 comes from pyridoxine hydrochloride.
Clean Label and Excipient Purity
No artificial dyes, titanium dioxide or talc are reported.

Dose, Safety & Label Transparency55

The label states 30 mg per serving and names the B6 source. The serving exceeds the European adult daily upper limit of 12 mg.
Vitamin B6 Dose & Safety Policy
The serving contains 30 mg per serving of B6. That exceeds the European adult daily upper limit of 12 mg.
Label Transparency
The B6 source is named as pyridoxine hydrochloride.

Value65

The cost per mg of B6 is moderate.
Vitamin B6 Price Efficiency
The cost per mg of B6 is moderate.
A Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value
Each serving provides 400 mcg folate from L-5-Methyltetrahydrofolate; a DFE amount is not established. The cost per serving is high. L-5-Methyltetrahydrofolate is an active form that bypasses the MTHFR conversion step.
How this ingredient is rated

Active Ingredient Quality & Bioavailability91

L-5-Methyltetrahydrofolate is an active form that bypasses the MTHFR conversion step. The L designation identifies the active form; no branded source is identified.
Folate Form Hierarchy
L-5-Methyltetrahydrofolate is an active form that bypasses the MTHFR conversion step.
Patented Sources & Isomeric Purity
The L designation identifies the active form; no branded source is identified.

Dose, Safety & Label Transparency100

Each serving provides 400 mcg folate from L-5-Methyltetrahydrofolate; a DFE amount is not established.
Folate Dosage by Declared Basis
Each serving provides 400 mcg folate from L-5-Methyltetrahydrofolate; a DFE amount is not established.

Value40

The cost per serving is high.
Price per Bioavailable Serving
The cost per serving is high.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  2. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  3. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  4. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  5. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  6. The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
    Ju Y; Xiong W; Pang Y; Chen Z; Hou J; Zheng S; Li Z; Liu T; Xia H; Xia M; Zhong Y; Li J; Jiang X · Biological trace element research · 2026
    Scoping review18 studies pooledBone Health forCopper
  7. Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
    Chen M; Jia L; Gao R · Frontiers in nutrition · 2024
    Cohort study5,286 participantsBone Health forCopper
  8. Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
    Hu M; Wang Z; Li C; Zheng Y; Hu J · Medicine · 2025
    Cross-sectional studyBone Health forCopper
  9. The association between dietary mineral intake and bone mineral density: a cross-sectional study.
    Wei M; Wei J; Huang S · Journal of health, population, and nutrition · 2025
    Cross-sectional study11,520 participantsBone Health forCopper
  10. Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
    Cui A; Yan J; Li H; Fan Z; Wei X; Wang H; Zhuang Y · PloS one · 2024
    Cross-sectional study6,965 participantsBone Health forCopper
  11. Association between RBC folate and lumbar bone mineral density in postmenopausal women, a cross-sectional study from NHANES 2009-2018.
    Wei H; Jin Z; Zhou L; Tang G; Chai S; Che X; Tan Y; Zeng W · Frontiers in endocrinology · 2025
    Cross-sectional study1,315 participantsBone Health forFolate
  12. Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density.
    Liu CT; Karasik D; Xu H; Zhou Y; Broe K; Cupples LA; Cpgm de Groot L; Ham A; Hannan MT; Hsu YH; Jacques P; McLean RR; Paul L; Selhub J; Trajanoska K; van der Velde N; van Schoor N; Kiel DP · The American journal of clinical nutrition · 2021
    Cohort study4,310 participantsBone Health forFolate
  13. Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
    Rondanelli M; Tartara A; Fossari F; Vecchio V; Faliva MA; Naso M; Perna S; Nichetti M; Peroni G · Current aging science · 2022
    Narrative review35,298 participants29 studies pooledBone Health forFolate Bone Health forVitamin B6
  14. Relation of homocysteine, folate, and vitamin B12 to bone mineral density of postmenopausal women.
    Cagnacci A; Baldassari F; Rivolta G; Arangino S; Volpe A · Bone · 2004
    Cross-sectional study161 participantsBone Health forFolate
  15. Dietary intake of folate, but not vitamin B2 or B12, is associated with increased bone mineral density 5 years after the menopause: results from a 10-year follow-up study in early postmenopausal women.
    Rejnmark L; Vestergaard P; Hermann AP; Brot C; Eiken P; Mosekilde L · Calcified tissue international · 2008
    Cohort study1,869 participantsBone Health forFolate
  16. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  17. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  18. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  19. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  20. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium