$27.27 $1.81 per serving
Product analysis
ProFema offers broad vitamin and mineral support for filling dietary gaps. Unidentified blend components make parts of the formula difficult to judge, and its broad coverage comes at a relatively high cost.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality65
Several nutrients have favorable identified forms, including folate, vitamin K and zinc. Unspecified vitamin D and blend forms, together with unknown mineral proportions, make quality less consistent across the formula.
Ingredient Transparency76
Ingredient amounts are stated and most forms are named. Several mixtures lack their proportions, and the blend components are not individually identified, making those parts difficult to assess.
Value For Money27
The full serving cost makes this an expensive way to obtain many individual nutrients. Biotin compares more favorably, while most other nutrient comparisons offer limited value.
Customer Satisfaction74
Customer ratings are favorable. The moderate review base gives some context to that feedback without establishing effectiveness.
Product Focus0
The formula suits broad nutritional coverage more than a narrowly targeted purpose. Its many ingredients and possible uses make benefits beyond correcting dietary gaps less clear.
- Format
Tablet - Container
- 60 Tablet(s)
- Per serving
- $1.81
- Customer rating
- 4.7 · 274 ratings
Goals
Impact
High effect
Magnesium · 200 mgVitamin C · 1000 mgZinc · 15 mgVitamin A · 4500 mcgVitamin D · 25 mcgSelenium · 150 mcg
Impact
Highest effect
Folate · 400 mcgVitamin B12 · 200 mcgVitamin D · 25 mcgMagnesium · 200 mgVitamin K · 50 mcgSelenium · 150 mcgZinc · 15 mgVitamin C · 1000 mg
Impact
High effect
Vitamin K · 50 mcgMagnesium · 200 mgCalcium · 200 mgVitamin D · 25 mcgCopper · 1.5 mgManganese · 2 mgZinc · 15 mgVitamin C · 1000 mg
Impact
Moderate effect
Iodine · 150 mcgVitamin D · 25 mcgVitamin B5 · 100 mgMagnesium · 200 mgRiboflavin · 34 mgThiamin · 30 mgVitamin B12 · 200 mcgPotassium · 30 mg
Vitamin B5 Not classified
No linked studies yet.
Impact
Moderate effect
Vitamin K · 50 mcgMagnesium · 200 mgVitamin B12 · 200 mcgVitamin B6 · 40 mgFolate · 400 mcgVitamin D · 25 mcg
Impact
High effect
Vitamin K · 50 mcgPotassium · 30 mgMagnesium · 200 mgVitamin D · 25 mcgSelenium · 150 mcgVitamin B12 · 200 mcgVitamin B6 · 40 mgVitamin E · 124.5 mgFolate · 400 mcgNiacin · 100 mgVitamin C · 1000 mg
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
Vitamin A (Beta-Carotene) | 4500 mcg | |
Vitamin C (Ascorbic Acid) | 1000 mg | |
Vitamin D3 | 25 mcg | |
Vitamin E (D-Alpha-Tocopheryl Succinate) | 124.5 mg | |
Vitamin K2 (Menaquinone-7) | 50 mcg | |
Thiamine (Thiamine Mononitrate) | 30 mg | |
Riboflavin | 34 mg | |
Niacin (Niacinamide) | 100 mg | |
Vitamin B6 (Pyridoxine Hydrochloride) | 40 mg | |
Folate (Glucosamine Salt, Quatrefolic (6S)-5-Methyltetrahydrofolic Acid) | 400 mcg | |
Vitamin B12 (Methylcobalamin) | 200 mcg | |
Biotin (D-Biotin) | 300 mcg | |
Pantothenic Acid (D-Calcium Pantothenate) | 100 mg | |
Choline (Choline Bitartrate) | 100 mg | |
Calcium (Calcium Citrate, Calcium D-Pantothenate) | 200 mg | |
Iodine (North Atlantic Kelp) | 150 mcg | |
Magnesium (Magnesium Citrate, Magnesium Oxide) | 200 mg | |
Zinc (Zinc Lactate) | 15 mg | |
Selenium (Selenium L-Methyl Selenocysteine) | 150 mcg | |
Copper (Copper Sebacate) | 1.5 mg | |
Manganese (Manganese Citrate) | 2 mg | |
Chromium (Chromium Polynicotinate) | 200 mcg | |
Molybdenum (Molybdenum Glycinate) | 25 mcg | |
Potassium (Potassium Citrate) | 30 mg | |
SuperFood Complex | 908 mg | |
Herbal Extracts | 700 mg | |
Co-Nutrients | 440.3 mg | |
Bioflavonoids | 400 mg | |
Minerals | 29 mg | |
Digestive Aids/Enzymes | 27 mg |
Iodine (North Atlantic Kelp) · 150 mcg OverallScore68
A serving provides 150 mcg of iodine at a high cost per serving. The amount fits the range for daily thyroid support. The chemical form of iodine is unknown. The marine source has an organic or geographic sourcing marker, though its exact detail is unspecified.
How this ingredient is rated
Active Ingredient Quality & Bioavailability61
The chemical form of iodine is unknown. The marine source has an organic or geographic sourcing marker, though its exact detail is unspecified.
Iodine Form & Bioavailability
The chemical form of iodine is unknown.
Marine Source Purity & Sourcing
The marine source has an organic or geographic sourcing marker, though its exact detail is unspecified.
Dose, Safety & Label Transparency100
The label lists 150 mcg of iodine per serving. The amount fits the range for daily thyroid support.
Dosage Efficacy for Daily Support
The amount fits the range for daily thyroid support.
Dosage Safety & Upper Limits
The serving is below the upper intake level.
Elemental Iodine Transparency
The label lists the iodine amount per serving.
Value20
The cost per serving is high.
Price Per Effective Serving
The cost per serving is high.
The serving provides 400 mcg of folate at a high cost per serving. It uses L-5-Methyltetrahydrofolate Glucosamine Salt. It is an active form of folate.
How this ingredient is rated
Active Ingredient Quality & Bioavailability100
L-5-MTHF is an active form that bypasses the MTHFR conversion step. A branded folate source is identified.
Folate Form Hierarchy
L-5-MTHF is an active form that bypasses the MTHFR conversion step.
Patented Sources & Isomeric Purity
A branded folate source is identified.
Dose, Safety & Label Transparency100
The declared amount is 400 mcg per serving.
Folate Dosage by Declared Basis
The declared amount is 400 mcg per serving.
Value10
The cost per serving is high.
Price per Bioavailable Serving
The cost per serving is high.
Selenium (Selenium L-Methyl Selenocysteine) · 150 mcg OverallScore77
A serving provides 150 mcg of selenium at a very high cost per 200 mcg. It supports daily selenium intake. The selenium source is Se-Methyl-L-Selenocysteine.
How this ingredient is rated
Active Ingredient Quality & Bioavailability100
The selenium source is Se-Methyl-L-Selenocysteine.
Selenium Chemical Form
The selenium source is Se-Methyl-L-Selenocysteine.
Form Transparency & Isomer Specificity
The label names Se-Methyl-L-Selenocysteine as the source.
Dose, Safety & Label Transparency88
150 mcg per serving provides selenium for daily maintenance. The 150 mcg serving is below the 400 mcg reference upper limit; selenium from food also contributes to total intake.
Dosage Efficacy Sweet Spot
150 mcg per serving provides selenium for daily maintenance.
Safety Margin & UL Adherence
The 150 mcg serving is below the 400 mcg reference upper limit; selenium from food also contributes to total intake.
Value10
The cost per 200 mcg of selenium is very high.
Price per 200 mcg Serving
The cost per 200 mcg of selenium is very high.
Alternative products
Report alternatives
Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
- Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
- The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
- The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
- Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
- The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
- Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
- Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
- The association between dietary mineral intake and bone mineral density: a cross-sectional study.
- Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
- Association between RBC folate and lumbar bone mineral density in postmenopausal women, a cross-sectional study from NHANES 2009-2018.
- Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density.
- Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
- Relation of homocysteine, folate, and vitamin B12 to bone mineral density of postmenopausal women.
- Dietary intake of folate, but not vitamin B2 or B12, is associated with increased bone mineral density 5 years after the menopause: results from a 10-year follow-up study in early postmenopausal women.
- Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
- Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
- Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
- An update on magnesium and bone health.
- Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.