$65.81 $2.19 per serving
Product analysis
ProFema supplies nutrients that support normal energy use, blood formation and immune function, especially when intake is low. Many components are relatively costly, and hidden blends make the full combination harder to judge.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality64
Several vitamins and minerals have favorable identified forms, including methylfolate and MK-7. Other forms and mixed-source proportions are less clear, leaving quality uneven across the complete formula.
Ingredient Transparency75
All listed amounts and most forms are disclosed. Hidden blend components and source proportions limit a full picture of what the mixture supplies.
Value For Money26
Many of the nutrients are relatively expensive for their content, including several favorable forms. A few fairer comparisons and uncertain ingredients do not establish strong value for the full formula.
Customer Satisfaction70
The limited customer feedback is very positive. The small number of ratings leaves uncertainty about how widely shared that satisfaction is.
Product Focus0
The formula’s clearest role is helping fill dietary gaps across several normal functions. Numerous ingredients, hidden blends and a very wide range of suggested uses make it poorly focused on a single purpose.
- Format
Tablet - Container
- 120 Tablet(s)
- Per serving
- $2.19
- Customer rating
- 4.6 · 92 ratings
Goals
Impact
High effect
Magnesium · 200 mgVitamin C · 1000 mgZinc · 15 mgVitamin A · 4500 mcgVitamin D · 25 mcgSelenium · 150 mcg
Impact
High effect
Vitamin K · 50 mcgMagnesium · 200 mgCalcium · 200 mgVitamin D · 25 mcgCopper · 1.5 mgManganese · 2 mgZinc · 15 mgVitamin C · 1000 mg
Impact
Lower effect
Folate · 400 mcgVitamin B12 · 200 mcgVitamin B6 · 40 mgMolybdenum · 25 mcgSelenium · 150 mcgMagnesium · 200 mgVitamin E · 124.5 mgZinc · 15 mgVitamin C · 1000 mgCholine · 100 mgRiboflavin · 34 mg
Riboflavin Not classified
No linked studies yet.
Vitamin B6 Not classified
No linked studies yet.
Impact
High effect
Biotin · 300 mcgVitamin D · 25 mcgZinc · 15 mgVitamin C · 1000 mg
Impact
Highest effect
Folate · 400 mcgVitamin B12 · 200 mcgVitamin D · 25 mcgMagnesium · 200 mgVitamin K · 50 mcgSelenium · 150 mcgZinc · 15 mgVitamin C · 1000 mg
Impact
Moderate effect
Biotin · 300 mcgNiacin · 100 mgVitamin B12 · 200 mcgRiboflavin · 34 mgThiamin · 30 mgVitamin B5 · 100 mgVitamin B6 · 40 mgVitamin D · 25 mcgZinc · 15 mgMagnesium · 200 mg
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
Vitamin A (Beta-Carotene) | 4500 mcg | |
Vitamin C (Ascorbic Acid) | 1000 mg | |
Vitamin D3 | 25 mcg | |
Vitamin E (D-Alpha-Tocopheryl Succinate) | 124.5 mg | |
Vitamin K2 (Menaquinone-7) | 50 mcg | |
Thiamine (Thiamine Mononitrate) | 30 mg | |
Riboflavin | 34 mg | |
Niacin (Niacinamide) | 100 mg | |
Vitamin B6 (Pyridoxine Hydrochloride) | 40 mg | |
Folate (Glucosamine Salt, Quatrefolic (6S)-5-Methyltetrahydrofolic Acid) | 400 mcg | |
Vitamin B12 (Methylcobalamin) | 200 mcg | |
Biotin (D-Biotin) | 300 mcg | |
Pantothenic Acid (D-Calcium Pantothenate) | 100 mg | |
Choline (Choline Bitartrate) | 100 mg | |
Calcium (Calcium Citrate, Calcium D-Pantothenate) | 200 mg | |
Iodine (North Atlantic Kelp) | 150 mcg | |
Magnesium (Magnesium Citrate, Magnesium Oxide) | 200 mg | |
Zinc (Zinc Lactate) | 15 mg | |
Selenium (Selenium L-Methyl Selenocysteine) | 150 mcg | |
Copper (Copper Sebacate) | 1.5 mg | |
Manganese (Manganese Citrate) | 2 mg | |
Chromium (Chromium Polynicotinate) | 200 mcg | |
Molybdenum (Molybdenum Glycinate) | 25 mcg | |
Potassium (Potassium Citrate) | 30 mg | |
SuperFood Complex | 908 mg | |
Herbal Extracts | 700 mg | |
Co-Nutrients | 440.3 mg | |
Bioflavonoids | 400 mg | |
Minerals | 29 mg | |
Digestive Aids/Enzymes | 27 mg |
Iodine (North Atlantic Kelp) · 150 mcg OverallScore68
The serving provides 150 mcg of iodine at a high cost per serving. The amount falls within the range for daily thyroid maintenance. The chemical form is unclear, and the marine source has a sourcing marker with no details specified.
How this ingredient is rated
Active Ingredient Quality & Bioavailability61
The chemical form of the marine iodine is unspecified. The marine source has a sourcing marker, but its details are not specified.
Iodine Form & Bioavailability
The chemical form of the marine iodine is unspecified.
Marine Source Purity & Sourcing
The marine source has a sourcing marker, but its details are not specified.
Dose, Safety & Label Transparency100
The label states 150 mcg of iodine per serving. That falls within the range for daily thyroid maintenance and below the upper intake level.
Dosage Efficacy for Daily Support
The 150 mcg serving falls within the range used for daily thyroid maintenance.
Dosage Safety & Upper Limits
The 150 mcg serving is below the 1,100 mcg upper intake level.
Elemental Iodine Transparency
The iodine amount is stated on the label.
Value20
The cost per serving is high.
Price Per Effective Serving
The cost per serving is high.
400 mcg of folate per serving comes at a very high cost. It uses L-5-Methyltetrahydrofolate Glucosamine Salt. It provides an active form of folate.
How this ingredient is rated
Active Ingredient Quality & Bioavailability100
It uses L-5-Methyltetrahydrofolate Glucosamine Salt. A branded folate source is indicated, though the brand name is not specified here.
Folate Form Hierarchy
L-5-MTHF is an active form that bypasses the MTHFR conversion step.
Patented Sources & Isomeric Purity
A branded folate source is indicated, though the brand name is not specified here.
Dose, Safety & Label Transparency100
The serving provides 400 mcg of folate.
Folate Dosage by Declared Basis
The serving provides 400 mcg of folate.
Value10
The cost per serving is very high.
Price per Bioavailable Serving
The cost per serving is very high.
Selenium (Selenium L-Methyl Selenocysteine) · 150 mcg OverallScore77
The serving supplies 150 mcg of selenium at a high cost for the amount provided. It uses Se-Methyl-L-Selenocysteine. The amount can support daily maintenance.
How this ingredient is rated
Active Ingredient Quality & Bioavailability100
It uses Se-Methyl-L-Selenocysteine.
Selenium Chemical Form
It uses Se-Methyl-L-Selenocysteine.
Form Transparency & Isomer Specificity
The form is named as Se-Methyl-L-Selenocysteine.
Dose, Safety & Label Transparency88
150 mcg per serving can support daily maintenance. The amount leaves room below the upper intake level for selenium from food.
Dosage Efficacy Sweet Spot
150 mcg per serving can support daily maintenance.
Safety Margin & UL Adherence
The serving is below the upper intake level, leaving room for selenium from food.
Value10
The cost is high for the amount of selenium provided.
Price per 200 mcg Serving
The cost is high for the amount of selenium provided.
Alternative products
Report alternatives
Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
- Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
- The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
- The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
- Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
- The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
- Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
- Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
- The association between dietary mineral intake and bone mineral density: a cross-sectional study.
- Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
- Association between RBC folate and lumbar bone mineral density in postmenopausal women, a cross-sectional study from NHANES 2009-2018.
- Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density.
- Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
- Relation of homocysteine, folate, and vitamin B12 to bone mineral density of postmenopausal women.
- Dietary intake of folate, but not vitamin B2 or B12, is associated with increased bone mineral density 5 years after the menopause: results from a 10-year follow-up study in early postmenopausal women.
- Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
- Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
- Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
- An update on magnesium and bone health.
- Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.