Advanced Nutrients

Advanced Nutrients

Thorne4.6 (1,094 ratings)
Format:Capsule Quantity: 240 Capsule(s) · 30 servings
Goals

Product analysis

53 out of 100

Advanced Nutrients may help fill a wide range of vitamin and mineral gaps and support normal energy, immune and bone functions. Several forms and mixture proportions are unspecified, making parts of the extensive formula harder to compare.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality58

Several clearly identified mineral and B-vitamin forms are quality strengths. Other forms are unspecified or lack enough information for a firm judgment, so quality is uneven across the formula.

Ingredient Transparency70

All listed amounts are stated, but some nutrient totals remain unresolved across serving declarations. Nine forms and the proportions of the quercetin mixture are missing, limiting a full comparison of the formula.

Value For Money29

The full serving cost compares poorly when considered for many of its individual nutrients. Some ingredients lack usable comparisons, so they cannot resolve the uncertainty about value for the broad combination.

Customer Satisfaction79

Customer ratings are very positive across a substantial review pool. The volume gives a broad view of satisfaction without proving the many intended health benefits.

Product Focus27

The strongest purpose is broad nutritional support when intake is low. The many ingredients and proposed goals make it less targeted, and larger amounts do not establish extra energy, sharper thinking or other added benefits when needs are already met.

Format
Capsule
Container
240 Capsule(s)
Per serving
$2.40
Customer rating
4.6 · 1,094 ratings
Report analysis

Goals

Immunity
Impact
Highest effect
C+ Ingredient FitA+ PathwaysA+ EvidenceA+ Formulation Logic
Magnesium · 250 mgVitamin C · 850 mgZinc · 15 mgVitamin A · 1.13 mgVitamin D · 50 mcgSelenium · 200 mcg

Zinc supports normal immune-cell function; the supplied evidence does not extend acute lozenge findings to routine use of this serving. Vitamin C contributes to immune nutrition and has modest support for shorter colds with regular use, rather than general infection prevention. Vitamin A supports normal barrier function. Copper, Folate, Vitamin B6, Vitamin B12, Selenium and Vitamin D support normal immune nutrition, with additional benefit mainly relevant when intake is low.

How this product is rated for Immunity

Ingredient fit65

Copper, Folate, Vitamin B6 and Vitamin B12 account for the main immune connection. Amounts and the wider formula limit how fully that connection is represented.
Goal fit
Relevant immune nutrients sit within a broader formula, so immunity is only part of its focus.
Dose adequacy
The amounts provide partial coverage of the saved comparisons; this is not a measure of the chance of benefit.

Pathways100

The strongest saved connection is lymphocyte function and immune regulation. Other covered areas follow the supplied nutrient and amount findings.
Depth
The strongest saved connection is lymphocyte function and immune regulation, rather than a prediction of resistance to infection.
Breadth
The main covered areas are barrier and antimicrobial defense, innate immune cell activity, lymphocyte function and immune regulation, oxidative and inflammatory balance. These describe the saved findings, not proven combined clinical effects.

Evidence100

Vitamin C provides the clearest evidence connection. The evidence supports the described roles, without establishing general infection prevention.
Evidence strength
Vitamin C provides the leading evidence connection here, within the supplied limits on normal nutrition and respiratory outcomes.
Studied preparation
The counted preparations match the saved comparisons; that does not imply superior forms or infection prevention.

Formulation logic100

The counted ingredients have no unmet partner requirement or configured conflict. Their amounts meet the saved minimum comparison.
Partner coverage
The counted ingredients have no unmet partner requirement in the supplied findings.
Conflicts
No configured ingredient conflict was identified. This finding does not assess every aspect of suitability.
Effective doses
All counted ingredients meet the saved minimum amount comparison; this is not proof of an effective clinical regimen.
Study evidence
Magnesium Supportive 8 studies
Selenium Mixed 37 studies
Vitamin A Supportive 107 studies
Vitamin C Supportive 53 studies
Vitamin D Supportive 85 studies
Vitamin E Supportive 21 studies
Zinc Supportive 73 studies
Impact
Highest effect
B- Ingredient FitA+ PathwaysA- EvidenceA+ Formulation Logic
Folate · 1.7 mg DFEVitamin B12 · 450 mcgVitamin D · 50 mcgMagnesium · 250 mgVitamin K · 100 mcgBoron · 3 mgSelenium · 200 mcgZinc · 15 mgVitamin C · 850 mg

B vitamins and folate contribute to normal metabolism and blood formation; calcium, magnesium and vitamin D contribute to mineral nutrition. Vitamin C, zinc and selenium supply nutrients used in normal antioxidant and immune functions. These roles chiefly matter when intake is low, and large amounts do not establish extra benefit. The selected eight-capsule serving differs from the catalogue serving, and niacin and vitamin K amounts remain unresolved.

How this product is rated for Everyday Health

Ingredient fit73

B vitamins, folate and the declared minerals provide the relevant connection. Niacin and vitamin K amounts are unresolved.
Goal fit
The meaningful connection comes from b vitamins, folate and the declared minerals; product naming and broader uses do not establish extra benefit.
Dose adequacy
Niacin and vitamin K amounts are unresolved. Other declared amounts provide the recognized contribution.

Pathways100

The relevant areas are nutrient metabolism, blood formation, mineral nutrition and antioxidant functions. Several nutritional areas have substantial representation.
Depth
The strongest contribution concerns nutrient metabolism, blood formation, mineral nutrition and antioxidant functions.
Breadth
Several nutritional areas have substantial representation.

Evidence86

Magnesium leads the saved finding. The supported role remains nutritional, without established added benefit above adequate intake.
Evidence strength
Magnesium provides the leading evidence contribution, subject to the supplied population and nutritional limits.
Studied preparation
The included preparations satisfy the supplied comparison; the finding does not establish superior effects from named forms or delivery methods.

Formulation logic97

No configured ingredient conflict was identified; this finding does not establish overall safety. Niacin and vitamin K amounts are unresolved.
Partner coverage
The included ingredients work independently or have their required partner; no extra combination benefit follows.
Conflicts
No configured ingredient conflict was identified; this finding does not establish overall safety.
Effective doses
Niacin and vitamin K amounts are unresolved. The other included ingredients meet the saved amount threshold.
Study evidence
Boron Supportive 6 studies
Folate Supportive 80 studies
Magnesium Supportive 114 studies
Selenium Supportive 70 studies
Vitamin C Supportive 56 studies
Vitamin D Supportive 115 studies
Vitamin K Supportive 34 studies
Zinc Supportive 60 studies
Impact
High effect
D+ Ingredient FitA+ PathwaysA EvidenceA+ Formulation Logic
Magnesium · 250 mgZinc · 15 mgVitamin D · 50 mcgBoron · 3 mg

Zinc helps maintain testosterone when zinc deficiency has lowered it; extra zinc has not shown an increase in zinc-replete men. Magnesium contributes to nutrient adequacy, but the supplied exercise-related study does not establish routine testosterone enhancement or a general effective amount. The zinc, magnesium and B6 combination trial did not improve androgen concentrations.

How this product is rated for Testosterone Support

Ingredient fit52

Boron, Magnesium, Selenium, Vitamin B6, Vitamin D, Zinc and Vitamin E are the main ingredients counted toward testosterone-related support, within a formula that also targets other needs.
Goal fit
Boron, Magnesium, Selenium, Vitamin B6, Vitamin D, Zinc and Vitamin E are the main ingredients counted toward testosterone-related support, within a formula that also targets other needs.
Dose adequacy
The declared serving amounts receive mixed but generally meaningful consideration; this compares amounts with supplied reference ranges, without proving a testosterone-related effect.

Pathways97

The strongest saved connection is to free-testosterone availability, based on the counted ingredients; this does not itself demonstrate a testosterone increase. Two testosterone-related-related areas reach the saved coverage threshold, although biological coverage does not guarantee broader testosterone-related benefits.
Depth
The strongest saved connection is to free-testosterone availability, based on the counted ingredients; this does not itself demonstrate a testosterone increase.
Breadth
Two testosterone-related-related areas reach the saved coverage threshold, although biological coverage does not guarantee broader testosterone-related benefits.

Evidence92

Zinc provides the strongest saved evidence contribution here; its population and outcome limitations still apply.
Evidence strength
Zinc provides the strongest saved evidence contribution here; its population and outcome limitations still apply.
Studied preparation
Vitamin B6 does not meet the saved studied-preparation criteria, limiting direct comparison with the reviewed preparations.

Formulation logic100

No listed ingredient conflict was matched in the supplied findings; this does not establish medication compatibility.
Partner coverage
The counted ingredients require no missing partner under the supplied findings; this does not imply an added benefit from combining them.
Conflicts
No listed ingredient conflict was matched in the supplied findings; this does not establish medication compatibility.
Effective doses
All counted ingredients meet the saved minimum amount criterion; this does not establish proven testosterone-raising doses.
Study evidence
Boron Disputed 3 studies
Magnesium Disputed 5 studies
Selenium No effect 16 studies
Vitamin D Supportive 56 studies
Vitamin E Disputed 3 studies
Zinc Disputed 7 studies
Impact
Moderate effect
C Ingredient FitF PathwaysA EvidenceA+ Formulation Logic
Iodine · 225 mcgVitamin D · 50 mcgVitamin B5 · 450 mgMagnesium · 250 mgRiboflavin · 10 mgThiamin · 40 mgVitamin B12 · 450 mcg

B12, folate, riboflavin, B5 and vitamin C help cover nutritional needs whose shortfalls can contribute to tiredness. Magnesium at 250 mg adds support for normal energy metabolism. Benefits are most relevant to inadequate intake; large B-vitamin amounts do not imply extra energy once needs are met.

How this product is rated for Energy

Ingredient fit63

Energy-related ingredients sit within a broader-purpose formula. Many relevant amounts are well represented against the saved reference levels, with some lower or unresolved amounts.
Goal fit
Energy-related ingredients sit within a broader-purpose formula.
Dose adequacy
Many relevant amounts are well represented against the saved reference levels, with some lower or unresolved amounts.

Pathways0

The saved findings show nutritional relevance without substantial coverage of the direct energy mechanisms. No energy mechanism reaches the saved coverage threshold.
Depth
The saved findings show nutritional relevance without substantial coverage of the direct energy mechanisms.
Breadth
No energy mechanism reaches the saved coverage threshold.

Evidence95

Vitamin D provides the strongest saved evidence at a qualifying amount. Nutrient status and ingredient-specific evidence limits still affect the practical benefit. The saved preparation match is incomplete for Iodine; the other qualifying ingredients satisfy that check.
Evidence strength
Vitamin D provides the strongest saved evidence at a qualifying amount. Nutrient status and ingredient-specific evidence limits still affect the practical benefit.
Studied preparation
The saved preparation match is incomplete for Iodine; the other qualifying ingredients satisfy that check.

Formulation logic98

The saved findings identify no missing required ingredient partner. Niacin falls below the saved amount threshold or has an unresolved amount; the remaining counted ingredients meet it.
Partner coverage
The saved findings identify no missing required ingredient partner.
Conflicts
No configured ingredient conflict was found in the supplied record.
Effective doses
Niacin falls below the saved amount threshold or has an unresolved amount; the remaining counted ingredients meet it.
Study evidence
Iodine Adverse 3 studies
Magnesium Supportive 4 studies
Thiamin Disputed 12 studies
Vitamin D Supportive 32 studies
Impact
High effect
D+ Ingredient FitA+ PathwaysB EvidenceA+ Formulation Logic
Vitamin D · 50 mcgMagnesium · 250 mgFolate · 1.7 mg DFEVitamin B12 · 450 mcgVitamin B6 · 10 mgVitamin C · 850 mg

Magnesium may support calming when magnesium status is low or in selected clinical settings; broad lasting everyday stress relief remains uncertain. B vitamins contribute to normal mood-related processes, but folate and B12 findings are indirect for psychological stress and B6 often appears in combination studies. Vitamin D and zinc have conditional support linked to nutritional status or selected clinical settings, without reliable broad stress relief in healthy adults.

How this product is rated for Stress Relief

Ingredient fit53

Relevant ingredients sit within a broader formula, so only part of the product is specifically connected to stress relief. Amounts provide only partial support against the saved references; small or unresolved amounts limit what can be attributed to the formula.
Goal fit
Relevant ingredients sit within a broader formula, so only part of the product is specifically connected to stress relief.
Dose adequacy
Amounts provide only partial support against the saved references; small or unresolved amounts limit what can be attributed to the formula.

Pathways100

The main recorded connection is mood and neurotransmitter synthesis. Several distinct stress-related processes reach the saved coverage threshold; this does not establish clinical benefit across all of them.
Depth
The strongest recorded connection concerns mood and neurotransmitter synthesis, with substantial coverage from the included ingredients.
Breadth
Several distinct stress-related processes reach the saved coverage threshold; this does not establish clinical benefit across all of them.

Evidence76

Magnesium provides the strongest recorded evidence. The qualifying preparations match the supplied evidence.
Evidence strength
Magnesium provides the strongest recorded ingredient evidence at a qualifying amount; its population and outcome limitations still apply.
Studied preparation
The qualifying preparations match those recognized in the supplied evidence; this does not show that the finished product was tested.

Formulation logic96

The ingredients work independently or have the required partner in the supplied findings. No listed formulation conflict was matched in the supplied findings. This is limited to the specified checks.
Partner coverage
The ingredients work independently or have the required partner in the supplied findings.
Conflicts
No listed formulation conflict was matched in the supplied findings. This is limited to the specified checks.
Effective doses
Some relevant ingredients have small or unresolved amounts and do not meet the saved minimum amount threshold.
Study evidence
Folate Supportive 19 studies
Magnesium Supportive 13 studies
Vitamin C Supportive 11 studies
Vitamin D Supportive 41 studies
Zinc Supportive 9 studies
Impact
High effect
C+ Ingredient FitC PathwaysA+ EvidenceA+ Formulation Logic
Folate · 1.7 mg DFEMagnesium · 250 mgVitamin B12 · 450 mcgVitamin K · 100 mcgVitamin D · 50 mcg

Vitamin C supports collagen formation; correcting low intake helps prevent skin fragility, without established extra anti-aging benefit when intake is adequate. Vitamin D helps preserve muscle function when deficiency is corrected. Vitamin B12 helps prevent neurological problems caused by deficiency.

How this product is rated for Longevity

Ingredient fit68

The saved findings count a range of ingredients and compare their amounts with reference amounts. Ingredient presence and amount alone do not establish anti-aging effects.
Goal fit
The mixture includes many ingredients serving other purposes, limiting its concentration on this goal.
Dose adequacy
The counted amounts provide partial coverage of the saved references; that comparison does not establish a clinically effective anti-aging dose.

Pathways60

The strongest saved coverage is antioxidant defence. Mechanistic coverage does not demonstrate lifespan extension.
Depth
The strongest saved coverage concerns antioxidant defence, a mechanistic finding rather than evidence of slower human aging.
Breadth
Only antioxidant defence reaches the saved coverage threshold; other routes remain limited.

Evidence98

Magnesium leads the saved evidence finding, but its functional study involved exercising older women and does not establish routine anti-aging efficacy.
Evidence strength
Magnesium leads the saved evidence finding, but its functional study involved exercising older women and does not establish routine anti-aging efficacy.
Studied preparation
The saved preparation check remains incomplete for Vitamin K, Boron. Clinical preparation equivalence cannot be assumed.

Formulation logic98

The saved findings show partner coverage and no matched ingredient conflicts. Some amount or preparation limits may still restrict practical relevance.
Partner coverage
The counted ingredients have their required partners or work independently under the saved findings; this does not demonstrate added benefit from combining them.
Conflicts
No ingredient conflict was matched in the supplied findings.
Effective doses
Lutein falls below the saved amount threshold; this differs from proof that the ingredient is ineffective.
Study evidence
Boron Not classified

No linked studies yet.

Folate Supportive 16 studies
Magnesium Supportive 12 studies
Selenium Supportive 27 studies
Vitamin C Supportive 30 studies
Vitamin D Supportive 50 studies
Vitamin E Supportive 19 studies
Vitamin K Supportive 27 studies
Zinc Supportive 10 studies

Ingredients

IngredientAmount per servingScore
Vitamin A
1.13 mg
Vitamin C (Ascorbic Acid)
850 mg 52
Vitamin D (Vitamin D3)
50 mcg
Vitamin E
134 mg
Vitamin K
100 mcg 66
Thiamine (Thiamine Hydrochloride)
40 mg 65
Riboflavin (Riboflavin 5'-Phosphate Sodium)
10 mg 68
Vitamin B6 (Pyridoxal 5-Phosphate)
10 mg
Folate
1.7 mg DFE
Vitamin B12 (Methylcobalamin)
450 mcg 67
Biotin
400 mcg 59
Pantothenic Acid (Calcium Pantothenate)
450 mg 75
Choline (Choline Citrate)
35 mg 50
Calcium (Dicalcium Malate)
250 mg 77
Iodine (Potassium Iodide)
225 mcg 84
Magnesium (DiMagnesium Malate)
250 mg 76
Zinc (Zinc Bisglycinate Chelate)
15 mg
Selenium (L-Selenomethionine)
200 mcg 82
Copper (Albion Copper Bisglycinate Chelate)
1.5 mg 78
Manganese (Albion Manganese Bisglycinate Chelate)
6 mg 84
Chromium (Chromium Nicotinate Glycinate Chelate)
200 mcg 76
Quercetin Phytosome (Phospholipid Complex, Sophora japonica Flower Extract)
100 mg
Bilberry extract
80 mg
Nicotinamide Riboside Hydrogen Malate
45 mg 59
Trans-Resveratrol
25 mg 73
Mixed Carotenoids
4 mg
Boron (Albion Bororganic)
3 mg 82
Gluten Free Adults 18–50
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
+4
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  2. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  3. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  4. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  5. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  6. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  7. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  8. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  9. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  10. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  11. The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
    Ju Y; Xiong W; Pang Y; Chen Z; Hou J; Zheng S; Li Z; Liu T; Xia H; Xia M; Zhong Y; Li J; Jiang X · Biological trace element research · 2026
    Scoping review18 studies pooledBone Health forCopper
  12. Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
    Chen M; Jia L; Gao R · Frontiers in nutrition · 2024
    Cohort study5,286 participantsBone Health forCopper
  13. Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
    Hu M; Wang Z; Li C; Zheng Y; Hu J · Medicine · 2025
    Cross-sectional studyBone Health forCopper
  14. The association between dietary mineral intake and bone mineral density: a cross-sectional study.
    Wei M; Wei J; Huang S · Journal of health, population, and nutrition · 2025
    Cross-sectional study11,520 participantsBone Health forCopper
  15. Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
    Cui A; Yan J; Li H; Fan Z; Wei X; Wang H; Zhuang Y · PloS one · 2024
    Cross-sectional study6,965 participantsBone Health forCopper
  16. Association between RBC folate and lumbar bone mineral density in postmenopausal women, a cross-sectional study from NHANES 2009-2018.
    Wei H; Jin Z; Zhou L; Tang G; Chai S; Che X; Tan Y; Zeng W · Frontiers in endocrinology · 2025
    Cross-sectional study1,315 participantsBone Health forFolate
  17. Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density.
    Liu CT; Karasik D; Xu H; Zhou Y; Broe K; Cupples LA; Cpgm de Groot L; Ham A; Hannan MT; Hsu YH; Jacques P; McLean RR; Paul L; Selhub J; Trajanoska K; van der Velde N; van Schoor N; Kiel DP · The American journal of clinical nutrition · 2021
    Cohort study4,310 participantsBone Health forFolate
  18. Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
    Rondanelli M; Tartara A; Fossari F; Vecchio V; Faliva MA; Naso M; Perna S; Nichetti M; Peroni G · Current aging science · 2022
    Narrative review35,298 participants29 studies pooledBone Health forFolate Bone Health forVitamin B6
  19. Relation of homocysteine, folate, and vitamin B12 to bone mineral density of postmenopausal women.
    Cagnacci A; Baldassari F; Rivolta G; Arangino S; Volpe A · Bone · 2004
    Cross-sectional study161 participantsBone Health forFolate
  20. Dietary intake of folate, but not vitamin B2 or B12, is associated with increased bone mineral density 5 years after the menopause: results from a 10-year follow-up study in early postmenopausal women.
    Rejnmark L; Vestergaard P; Hermann AP; Brot C; Eiken P; Mosekilde L · Calcified tissue international · 2008
    Cohort study1,869 participantsBone Health forFolate