Prenatal Essentials Methyl-Free

Prenatal Essentials Methyl-Free

Seeking Health4.9 (1,076 ratings)
Format:Capsule Quantity: 60 Capsule(s) · 30 servings
Goals
$38.00 $1.26 per serving

Product analysis

59 out of 100

Prenatal Essentials Methyl-Free provides broad nutritional support for normal metabolism, blood formation and bone needs when intake is low. Many nutrient contributions are relatively expensive at the full serving price.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality65

Several B vitamins and minerals have favorable identified forms. Comparative quality remains uncertain for some other nutrients, and the methyl free label does not establish a quality advantage on its own.

Ingredient Transparency79

All listed amounts and nearly all forms are stated, making much of the serving easy to compare. The proportions of two combined sources are not disclosed.

Value For Money29

Many nutrient contributions are expensive at the full serving price, including vitamin K, riboflavin and several minerals. The methyl free format alone does not establish better value.

Customer Satisfaction86

Customers report very high satisfaction across around a thousand ratings. The substantial feedback base supports a reasonably established satisfaction pattern.

Product Focus35

The clearest role is filling nutrient gaps relevant to normal metabolism, blood formation and bone needs. Larger amounts and a methyl free formula do not establish extra energy, while the calcium contribution remains unresolved.

Format
Capsule
Container
60 Capsule(s)
Per serving
$1.26
Customer rating
4.9 · 1,076 ratings
Report analysis

Goals

Impact
Highest effect
B- Ingredient FitA+ PathwaysA- EvidenceA+ Formulation Logic
Folate · 1360 mcg DFEVitamin B12 · 100 mcgVitamin D · 25 mcgMagnesium · 100 mgVitamin K · 100 mcgBoron · 1 mgZinc · 13 mgVitamin C · 100 mg

B vitamins supply nutrients involved in normal energy metabolism. Folate contribute to normal blood formation. Vitamin D and Vitamin K supply nutrients involved in bone and mineral functions. Zinc contributes to normal antioxidant and immune functions. The nutritional contributions can help when intake is low; added benefit above adequate intake is not established. Calcium is declared but its eligible amount is unresolved.

How this product is rated for Everyday Health

Ingredient fit74

The relevant vitamins and minerals provide the supported focus, alongside other actives whose broad-health relevance is less established. The included amounts make a partial contribution to the saved comparison; smaller or unresolved quantities limit the overall contribution.
Goal fit
The relevant vitamins and minerals provide the supported focus, alongside other actives whose broad-health relevance is less established.
Dose adequacy
The included amounts make a partial contribution to the saved comparison; smaller or unresolved quantities limit the overall contribution.

Pathways100

The strongest area is energy metabolism cofactors, with substantial coverage from the relevant ingredients.
Depth
The strongest area is energy metabolism cofactors, with substantial coverage from the relevant ingredients.
Breadth
The areas reaching the saved coverage threshold are energy metabolism cofactors, one-carbon metabolism and blood formation, bone and mineral metabolism.

Evidence86

Magnesium contributes most strongly to the saved evidence finding; its role remains subject to the supplied nutritional or preparation-specific limitations.
Evidence strength
Magnesium contributes most strongly to the saved evidence finding; its role remains subject to the supplied nutritional or preparation-specific limitations.
Studied preparation
The eligible preparations match those accepted in the saved findings, without implying superior forms or broader clinical benefits.

Formulation logic98

None of the evaluated ingredient conflicts was triggered. The relevant ingredients can contribute independently or have their required partner present; no extra combined effect is established.
Partner coverage
The relevant ingredients can contribute independently or have their required partner present; no extra combined effect is established.
Conflicts
None of the evaluated ingredient conflicts was triggered.
Effective doses
Calcium falls short of the saved amount comparison because its eligible amount is unresolved or too small; other included ingredients meet it.
Study evidence
Boron Supportive 6 studies
Folate Supportive 80 studies
Magnesium Supportive 114 studies
Vitamin C Supportive 56 studies
Vitamin D Supportive 115 studies
Vitamin K Supportive 34 studies
Zinc Supportive 60 studies
Impact
Moderate effect
C- Ingredient FitF PathwaysA EvidenceA+ Formulation Logic
Iodine · 220 mcgVitamin D · 25 mcgVitamin B5 · 20 mgMagnesium · 100 mgRiboflavin · 10 mgThiamin · 5 mgVitamin B12 · 100 mcg

B vitamins support normal energy metabolism, and folate and vitamin B12 help maintain nutrient status relevant to fatigue. Magnesium at 100 mg adds nutritional support, while vitamin C and vitamin D may matter when low status contributes to tiredness. Larger amounts and a methyl-free formula do not establish extra energy in a well-nourished person.

How this product is rated for Energy

Ingredient fit59

Relevant energy-related ingredients are present alongside ingredients serving other needs. The relevant amounts provide a partial match to the supplied dose comparisons.
Goal fit
Relevant energy-related ingredients are present alongside ingredients serving other needs.
Dose adequacy
The relevant amounts provide a partial match to the supplied dose comparisons.

Pathways0

The saved findings show nutritional support without meaningful coverage of the listed energy mechanisms. The saved findings show limited reach across the different aspects of energy support.
Depth
The saved findings show nutritional support without meaningful coverage of the listed energy mechanisms.
Breadth
The saved findings show limited reach across the different aspects of energy support.

Evidence94

Vitamin D provides the strongest relevant evidence at the assessed amount, with benefits dependent on nutritional status or clinical context. Most qualifying ingredients match preparations represented in the supplied evidence; iodine did not match.
Evidence strength
Vitamin D provides the strongest relevant evidence at the assessed amount, with benefits dependent on nutritional status or clinical context.
Studied preparation
Most qualifying ingredients match preparations represented in the supplied evidence; iodine did not match.

Formulation logic100

The assessed ingredients can contribute on their own or have their required partner present. No ingredient conflicts were identified in the saved assessment. All assessed ingredients met the saved minimum amount criterion.
Partner coverage
The assessed ingredients can contribute on their own or have their required partner present.
Conflicts
No ingredient conflicts were identified in the saved assessment.
Effective doses
All assessed ingredients met the saved minimum amount criterion.
Study evidence
Iodine Adverse 3 studies
Magnesium Supportive 4 studies
Thiamin Disputed 12 studies
Vitamin D Supportive 32 studies
Heart Health
Impact
High effect
D+ Ingredient FitC PathwaysA- EvidenceA+ Formulation Logic
Vitamin K · 100 mcgMagnesium · 100 mgVitamin B12 · 100 mcgVitamin B6 · 15 mgFolate · 1360 mcg DFEVitamin D · 25 mcg

Magnesium contributes to the balance of minerals and blood-vessel tone, although blood-pressure effects in trials are small and inconsistent. Folate, B6 and B12 participate in homocysteine processing, but lowering this blood marker has not generally reduced major cardiac outcomes. MK-7 vitamin K has limited support for arterial-stiffness measures, particularly from studies in postmenopausal women; this does not establish prevention of heart attacks.

How this product is rated for Heart Health

Ingredient fit52

Relevant nutrients sit within a broader formula, and their amounts provide differing levels of exposure comparison.
Goal fit
The formula includes relevant nutrients alongside ingredients aimed at other goals, reducing its heart-health focus.
Dose adequacy
The counted amounts provide partial exposure comparisons, with lower amounts limiting the expected contribution.

Pathways60

Homocysteine processing is the strongest finding, although changing this marker does not establish fewer cardiac events.
Depth
Homocysteine processing is the strongest finding, although changing this marker does not establish fewer cardiac events.
Breadth
One area reaches the saved comparison threshold, so the findings remain concentrated rather than spanning several heart-health mechanisms.

Evidence89

Magnesium leads the evidence finding, although blood-pressure results are small and inconsistent.
Evidence strength
Magnesium leads the evidence finding, although blood-pressure results are small and inconsistent.
Studied preparation
The counted preparations match the saved study comparison; matching a preparation alone does not establish the same benefit for every user.

Formulation logic100

The counted ingredients have no missing required partner or identified configured conflict. Their amounts meet the saved minimum comparison.
Partner coverage
No required partner is missing for the counted ingredients; this does not establish an extra benefit from combining them.
Conflicts
No configured ingredient conflict was identified in the supplied facts.
Effective doses
The counted ingredients meet the saved minimum amount comparison; this threshold does not prove clinical effectiveness.
Study evidence
Folate Supportive 116 studies
Magnesium Supportive 158 studies
Niacin Supportive 105 studies
Vitamin B6 Supportive 44 studies
Vitamin D Mixed 164 studies
Vitamin K Mixed 62 studies
Impact
High effect
D+ Ingredient FitD- PathwaysA+ EvidenceA+ Formulation Logic
Folate · 1360 mcg DFEVitamin B12 · 100 mcgVitamin B6 · 15 mgMolybdenum · 50 mcgMagnesium · 100 mgVitamin E · 50 mgZinc · 13 mgVitamin C · 100 mgRiboflavin · 10 mg

Folate supports normal metabolism, but the toxin-related findings concern folic acid in arsenic-exposed populations and do not transfer automatically to calcium folinate. Several mineral and vitamin cofactors also receive saved credit without establishing additional toxin clearance. Vitamin C at 100 mg per serving is below the comparison's inclusion threshold. The nutrient forms do not establish a superior detoxification effect.

How this product is rated for Liver & Detox

Ingredient fit52

Several nutrients receive credit, while the wider formula contains actives intended for other goals.
Goal fit
Several nutrients receive credit, while the wider formula contains actives intended for other goals.
Dose adequacy
Declared nutrient amounts contribute unevenly; smaller quantities fall below inclusion, and full amount credit does not establish toxin clearance.

Pathways43

The saved findings concentrate on methyl-group supply; this describes assigned biological coverage rather than demonstrated toxin removal.
Depth
The strongest assigned coverage concerns methyl-group supply, without demonstrating greater removal of toxins.
Breadth
Only methyl-group supply reaches the coverage threshold; the other tracked areas do not.

Evidence97

Folate receives the strongest assigned evidence weight, but its toxin-related findings are specific to exposure, nutritional status and folic-acid regimens.
Evidence strength
Folate receives the strongest assigned evidence weight, but its toxin-related findings are specific to exposure, nutritional status and folic-acid regimens.
Studied preparation
Most credited preparations are recognized; Molybdenum, Vitamin B2 (Riboflavin), Vitamin B6 are not recognized as studied preparations.

Formulation logic100

Credited ingredients have no missing required partner, and no configured ingredient conflict was identified.
Partner coverage
Every credited ingredient works independently or has its required partner; this does not establish a combined clearance benefit.
Conflicts
No configured ingredient conflict was identified.
Effective doses
Every credited ingredient meets the comparison's amount threshold; this is not proof of an effective toxin-clearance dose.
Study evidence
Folate Supportive 16 studies
Magnesium Supportive 19 studies
Vitamin C Supportive 9 studies
Vitamin E Supportive 23 studies
Zinc Supportive 30 studies
Hair Health
Impact
Moderate effect
C- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 150 mcgVitamin D · 25 mcgZinc · 13 mgVitamin C · 100 mg

Zinc may help reduce diffuse shedding when low zinc is the cause. Getting enough matters, but extra zinc isn't known to regrow hair when your intake is already adequate. The other vitamins and minerals have normal biological roles, but those roles alone don't show that taking more will increase hair growth.

How this product is rated for Hair Health

Ingredient fit60

Zinc provides the main practical connection to hair here. Amounts and ingredient identity don't determine the cause of hair loss.
Goal fit
Several ingredients relate to hair or nutrient adequacy, alongside ingredients intended for other purposes.
Dose adequacy
One selected serving provides Vitamin B7 (Biotin) 150 mcg, Copper 0.75 mg, Vitamin B9 (Folate) 1360 mcg DFE. These amounts don't determine an individual hair-treatment dose.

Pathways3

The ingredients relate mainly to the materials involved in hair fibres, with limited hair-specific benefit.
Depth
The ingredients relate mainly to the materials involved in hair fibres, with limited hair-specific benefit.
Breadth
The main connection is limited to particular hair-related processes; it doesn't imply action on every cause of hair loss.

Evidence97

Zinc's clearest hair benefit concerns shedding caused by low zinc, rather than regrowth when zinc intake is adequate. Iodine supports thyroid hormone production, but its form doesn't demonstrate routine treatment of hair loss.
Evidence strength
Zinc's clearest hair benefit concerns shedding caused by low zinc, rather than regrowth when zinc intake is adequate.
Studied preparation
Iodine supports thyroid hormone production, but its form doesn't demonstrate routine treatment of hair loss.

Formulation logic100

No required partner or particular ingredient conflict is identified. Ingredient amounts don't by themselves confirm a hair benefit.
Partner coverage
No required ingredient partner is missing for the ingredients considered here.
Conflicts
No particular ingredient conflict is identified for this goal.
Effective doses
The relevant declared amounts reach the lower comparison range, which isn't a guarantee of hair benefit.
Study evidence
Biotin Supportive 4 studies
Copper Adverse 4 studies
Folate Mixed 15 studies
Iodine No effect 1 study
Niacin Disputed 2 studies
Vitamin A Disputed 13 studies
Vitamin D Disputed 34 studies
Vitamin E No effect 3 studies
Zinc Supportive 22 studies
Bone Health
Impact
Highest effect
C- Ingredient FitA+ PathwaysA+ EvidenceA+ Formulation Logic
Vitamin K · 100 mcgMagnesium · 100 mgCalcium · 100 mgVitamin D · 25 mcgCopper · 0.75 mgManganese · 2 mgBoron · 1 mgZinc · 13 mgVitamin C · 100 mg

Vitamin D supports calcium absorption, and magnesium contributes to normal bone metabolism when intake is low. The calcium amount is undisclosed, so its mineral contribution cannot be quantified. Identified MK-7 at 100 mcg per serving provides partial exposure compared with the postmenopausal bone-density trial; copper and vitamin C matter in deficiency, without establishing pregnancy-specific skeletal benefit.

How this product is rated for Bone Health

Ingredient fit59

Vitamin D, magnesium and identified MK-7 are relevant; calcium has no usable amount.
Goal fit
Vitamin D, magnesium and identified MK-7 are relevant; calcium has no usable amount.
Dose adequacy
The unknown calcium amount limits mineral assessment; MK-7 provides partial study exposure.

Pathways100

Collagen matrix formation is the strongest represented area in the saved findings. Calcium absorption, bone-protein activation and collagen matrix meet the saved coverage requirement; other areas have more limited representation.
Depth
Collagen matrix formation is the strongest represented area in the saved findings.
Breadth
Calcium absorption, bone-protein activation and collagen matrix meet the saved coverage requirement; other areas have more limited representation.

Evidence98

Identified MK-7 leads the saved evidence finding, with limited, mixed postmenopausal bone-density evidence. The included preparations match those recognized in the saved findings, without establishing additional benefit from form selection.
Evidence strength
Identified MK-7 leads the saved evidence finding, with limited, mixed postmenopausal bone-density evidence.
Studied preparation
The included preparations match those recognized in the saved findings, without establishing additional benefit from form selection.

Formulation logic96

Vitamin D lacks a qualifying partner in the saved findings, limiting its supported role within this serving. Calcium's unknown amount limits the amount finding.
Partner coverage
Vitamin D lacks a qualifying partner in the saved findings, limiting its supported role within this serving.
Conflicts
No listed ingredient conflict was triggered by the supplied facts.
Effective doses
Calcium has no disclosed amount; the remaining included nutrients meet the saved minimum amount comparison.
Study evidence
Boron Supportive 5 studies
Calcium Supportive 144 studies
Copper Disputed 20 studies
Folate Supportive 50 studies
Magnesium Supportive 48 studies
Manganese Adverse 12 studies
Vitamin A Adverse 56 studies
Vitamin C Supportive 46 studies
Vitamin D Supportive 202 studies
Vitamin K Supportive 78 studies
Zinc Supportive 33 studies

Ingredients

IngredientAmount per servingScore
Vitamin A (Beta-Carotene, Retinyl Palmitate)
1500 mcg RAE
Vitamin C (Ascorbic Acid)
100 mg
Vitamin D3 (Cholecalciferol)
25 mcg
Vitamin E (Novatol)
50 mg
Thiamine (Thiamine Hydrochloride)
5 mg
Riboflavin (Riboflavin 5-Phosphate)
10 mg 68
Niacin (Niacinamide)
25 mg 65
Vitamin B6 (Pyridoxal 5-Phosphate)
15 mg 72
Folate (Calcium Folinate)
1360 mcg DFE
Vitamin B12 (Adenosylcobalamin, Hydroxocobalamin)
100 mcg
Biotin
150 mcg
Pantothenic Acid (D-Calcium Pantothenate)
20 mg 61
DimaCal (Calcium)
100 mg
Iodine (Potassium Iodide)
220 mcg 84
Magnesium (Dimagnesium Malate)
100 mg
Zinc (Zinc Bisglycinate Chelate)
13 mg
SelenoExcell (Selenium)
50 mcg
Copper (Copper Bisglycinate Chelate)
0.75 mg 56
Manganese (Manganese Bisglycinate Chelate)
2 mg 78
Chromium (Chromium Nicotinate Glycinate Chelate)
100 mcg 47
Molybdenum (Molybdenum Glycinate Chelate)
50 mcg 64
Boron (Boroganic Glycine)
1 mg 74
Lutein (Marigold flower extract)
1 mg
Zeaxanthin (Marigold flower extract)
1 mg
Vitamin K2 (Menaquinone-7)
100 mcg 73
Gluten Free Dairy Free Pregnant Women 18–50
Report overview
A+ Ingredient Form & Label QualityC+ Dose, Safety & Label TransparencyF Value
A serving provides 15 mg of vitamin B6, above the European adult daily upper limit. The identified form is pyridoxal 5-phosphate.
How this ingredient is rated

Ingredient Form & Label Quality100

The identified vitamin B6 form is pyridoxal 5-phosphate. The saved facts do not flag the artificial colors, titanium dioxide or talc checked by the evaluation.
Vitamin B6 Form Identification
The saved facts identify pyridoxal 5-phosphate as the vitamin B6 source.
Clean Label and Excipient Purity
The saved facts do not flag the artificial colors, titanium dioxide or talc checked by the evaluation.

Dose, Safety & Label Transparency69

15 mg of vitamin B6 per serving exceeds the European adult daily upper limit. The chemical source is identified.
Vitamin B6 Dose & Safety Policy
15 mg of vitamin B6 per serving exceeds the European adult daily upper limit.
Label Transparency
The saved facts identify pyridoxal 5-phosphate as the vitamin B6 source.

Value19

At about $1.27 per whole-product serving, the cost is relatively high in relation to its vitamin B6 amount.
Vitamin B6 Price Efficiency
The whole-product serving costs about $1.27 and provides 15 mg of vitamin B6.
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
Each serving supplies 220 mcg of iodine as potassium iodide. A whole-product serving costs about $1.27.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

The iodine is supplied as potassium iodide, a form favored by the evaluation.
Iodine Form & Bioavailability
Potassium iodide is the disclosed form of iodine, and the evaluation favors this form.
Marine Source Purity & Sourcing
No marine source is identified in the available facts, so the marine-specific purity criterion does not apply.

Dose, Safety & Label Transparency100

Each serving provides 220 mcg of iodine, and the amount is disclosed. The evaluation does not flag it for high iodine content.
Dosage Efficacy for Daily Support
The serving provides 220 mcg of iodine, an amount the evaluation favors for routine iodine intake.
Dosage Safety & Upper Limits
The amount does not trigger the evaluation’s high-iodine warning.
Elemental Iodine Transparency
The iodine amount is stated as 220 mcg per serving.

Value20

A whole-product serving costs about $1.27.
Price Per Effective Serving
A whole-product serving costs about $1.27.
A- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyF Value
Each serving provides 25 mg of niacin as niacinamide, a form generally associated with less flushing than nicotinic acid. The whole-product serving costs about $1.27.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

Niacinamide is the identified vitamin B3 form in the saved facts.
Niacin Form & Goal Alignment
Niacinamide is the identified vitamin B3 form in the saved facts.
Precursor Source Quality
The identified source is conventional niacinamide; the saved facts do not identify an NR or NMN source.

Dose, Safety & Label Transparency67

The saved facts record 25 mg of niacin per serving as niacinamide, a form generally associated with less flushing than nicotinic acid.
Clarity of Chemical Form
Niacinamide is identified as the niacin form.
Form-Specific Dosage Efficacy
The saved facts record 25 mg of niacin per serving as niacinamide.
Flush Risk & Safety Labeling
Niacinamide is generally associated with less flushing than nicotinic acid; no no-flush claim is captured in the saved facts.

Value20

The whole-product serving costs about $1.27; it includes the other ingredients in the serving.
Price Per Effective Serving
The whole-product serving costs about $1.27; it includes the other ingredients in the serving.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  2. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  3. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  4. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  5. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  6. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  7. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  8. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  9. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  10. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  11. The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
    Ju Y; Xiong W; Pang Y; Chen Z; Hou J; Zheng S; Li Z; Liu T; Xia H; Xia M; Zhong Y; Li J; Jiang X · Biological trace element research · 2026
    Scoping review18 studies pooledBone Health forCopper
  12. Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
    Chen M; Jia L; Gao R · Frontiers in nutrition · 2024
    Cohort study5,286 participantsBone Health forCopper
  13. Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
    Hu M; Wang Z; Li C; Zheng Y; Hu J · Medicine · 2025
    Cross-sectional studyBone Health forCopper
  14. The association between dietary mineral intake and bone mineral density: a cross-sectional study.
    Wei M; Wei J; Huang S · Journal of health, population, and nutrition · 2025
    Cross-sectional study11,520 participantsBone Health forCopper
  15. Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
    Cui A; Yan J; Li H; Fan Z; Wei X; Wang H; Zhuang Y · PloS one · 2024
    Cross-sectional study6,965 participantsBone Health forCopper
  16. Association between RBC folate and lumbar bone mineral density in postmenopausal women, a cross-sectional study from NHANES 2009-2018.
    Wei H; Jin Z; Zhou L; Tang G; Chai S; Che X; Tan Y; Zeng W · Frontiers in endocrinology · 2025
    Cross-sectional study1,315 participantsBone Health forFolate
  17. Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density.
    Liu CT; Karasik D; Xu H; Zhou Y; Broe K; Cupples LA; Cpgm de Groot L; Ham A; Hannan MT; Hsu YH; Jacques P; McLean RR; Paul L; Selhub J; Trajanoska K; van der Velde N; van Schoor N; Kiel DP · The American journal of clinical nutrition · 2021
    Cohort study4,310 participantsBone Health forFolate
  18. Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
    Rondanelli M; Tartara A; Fossari F; Vecchio V; Faliva MA; Naso M; Perna S; Nichetti M; Peroni G · Current aging science · 2022
    Narrative review35,298 participants29 studies pooledBone Health forFolate Bone Health forVitamin B6
  19. Relation of homocysteine, folate, and vitamin B12 to bone mineral density of postmenopausal women.
    Cagnacci A; Baldassari F; Rivolta G; Arangino S; Volpe A · Bone · 2004
    Cross-sectional study161 participantsBone Health forFolate
  20. Dietary intake of folate, but not vitamin B2 or B12, is associated with increased bone mineral density 5 years after the menopause: results from a 10-year follow-up study in early postmenopausal women.
    Rejnmark L; Vestergaard P; Hermann AP; Brot C; Eiken P; Mosekilde L · Calcified tissue international · 2008
    Cohort study1,869 participantsBone Health forFolate