Special Two

Special Two

NOW4.7 (1,719 ratings)
Format:Capsule Quantity: 240 Capsule(s) · 60 servings
Goals
$16.96 $0.28 per serving

Product analysis

55 out of 100

Special Two combines broad vitamin and mineral coverage with botanicals and enzymes. Several well-identified mineral sources work in its favor, but the large mixture and incomplete combination breakdowns make the extras harder to judge.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality52

Several mineral forms are clearly identified, including zinc picolinate and copper and manganese chelates. Other preparations are less favored or unresolved, so quality is uneven across the large mixture.

Ingredient Transparency71

Ingredient amounts are disclosed. Incomplete preparation details limit like-for-like comparisons.

Value For Money51

Value is favorable for several vitamin and mineral contributions, including vitamin E, B6 and iodine. Other ingredients compare less favorably or have no dependable value comparison, so the full mixture has mixed value.

Customer Satisfaction84

Customer ratings are strongly favorable. A large rating pool provides a broader view of customer satisfaction.

Product Focus13

The formula serves broad nutritional needs rather than a narrowly targeted purpose. Its many botanicals and enzymes make their individual contributions harder to distinguish.

Format
Capsule
Container
240 Capsule(s)
Per serving
$0.28
Customer rating
4.7 · 1,719 ratings
Report analysis

Goals

Impact
Moderate effect
D Ingredient FitF PathwaysA+ EvidenceA Formulation Logic
Zinc · 15 mgVitamin C · 500 mgCopper · 1 mgSelenium · 50 mcgLycopene · 250 mcgGreen Tea · 50 mgVitamin E · 200 IU
Study evidence
Biotin Supportive 10 studies
Copper Supportive 16 studies
Green Tea Supportive 37 studies
Lycopene Supportive 20 studies
Niacin Supportive 61 studies
Selenium Supportive 22 studies
Vitamin A Supportive 106 studies
Vitamin C Supportive 53 studies
Vitamin E Supportive 38 studies
Zinc Supportive 66 studies
Impact
Moderate effect
F Ingredient FitC PathwaysA- EvidenceA Formulation Logic
Zinc · 15 mgVitamin E · 200 IUVitamin C · 500 mgCopper · 1 mgVitamin A · 10000 IU
Study evidence
Copper Supportive 7 studies
Lycopene Supportive 5 studies
Riboflavin Supportive 69 studies
Rutin Not classified 1 study
Selenium Supportive 15 studies
Vitamin A Supportive 65 studies
Vitamin C Disputed 24 studies
Vitamin D Disputed 35 studies
Vitamin E Disputed 35 studies
Zinc Supportive 39 studies
Impact
High effect
C Ingredient FitA+ PathwaysB+ EvidenceA+ Formulation Logic
Folate · 400 mcgVitamin B12 · 100 mcgVitamin D · 400 IUMagnesium · 50 mgSelenium · 50 mcgZinc · 15 mgVitamin C · 500 mg
Study evidence
Bromelain Supportive 11 studies
Folate Supportive 80 studies
Magnesium Supportive 114 studies
Selenium Supportive 70 studies
Vitamin C Supportive 56 studies
Vitamin D Supportive 115 studies
Zinc Supportive 60 studies
Impact
Moderate effect
C- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Iodine · 150 mcgVitamin D · 400 IUVitamin B5 · 50 mgMagnesium · 50 mgRiboflavin · 50 mgThiamin · 50 mgVitamin B12 · 100 mcgIron · 10 mgPotassium · 50 mg
Study evidence
Iodine Adverse 3 studies
Iron Supportive 74 studies
Magnesium Supportive 4 studies
Potassium Supportive 2 studies
Thiamin Disputed 12 studies
Vitamin D Supportive 32 studies
Immunity
Impact
High effect
D- Ingredient FitC+ PathwaysA+ EvidenceA+ Formulation Logic
Magnesium · 50 mgVitamin C · 500 mgZinc · 15 mgVitamin A · 10000 IUVitamin D · 400 IUSelenium · 50 mcg
Study evidence
Bromelain Not classified 1 study
Green Tea Not classified 2 studies
Iron Supportive 23 studies
Magnesium Supportive 8 studies
Selenium Mixed 37 studies
Vitamin A Supportive 107 studies
Vitamin C Supportive 53 studies
Vitamin D Supportive 85 studies
Vitamin E Supportive 21 studies
Zinc Supportive 73 studies
Impact
Moderate effect
F Ingredient FitD- PathwaysA- EvidenceA Formulation Logic
Vitamin D · 400 IUVitamin E · 200 IUVitamin C · 500 mgBlue-Green Algae · 400 mgGreen Tea · 50 mg
Study evidence
Bromelain Supportive 12 studies
Lycopene Supportive 15 studies
Magnesium Supportive 41 studies
Papain Not classified

No linked studies yet.

Rutin Supportive 6 studies
Selenium Supportive 34 studies
Vitamin C Supportive 50 studies
Vitamin D Supportive 101 studies
Vitamin E Supportive 20 studies
Zinc Supportive 64 studies

Ingredients

IngredientAmount per servingScore
Vitamin A (Beta-Carotene)
10000 IU 73
Vitamin C (Ascorbic Acid, Calcium Ascorbate)
500 mg 73
Vitamin D (Ergocalciferol)
400 IU 35
Vitamin E (D-Alpha-Tocopheryl Succinate)
200 IU 72
Thiamine (Thiamine Hydrochloride)
50 mg 76
Riboflavin
50 mg 68
Niacin (Niacinamide)
50 mg 65
Vitamin B6 (Pyridoxine Hydrochloride)
50 mg 75
Folate (Folic Acid)
400 mcg 14
Vitamin B12 (Cyanocobalamin)
100 mcg 21
Biotin
100 mcg
Pantothenic Acid (Calcium Pantothenate)
50 mg 70
Calcium (Calcium Ascorbate, Calcium Carbonate)
100 mg
Iron (Ferrochel Iron Bisglycinate)
10 mg 69
Iodine (Potassium Iodide)
150 mcg 96
Magnesium (Magnesium Oxide)
50 mg
Zinc (Zinc Picolinate)
15 mg 88
Selenium (L-Selenomethionine)
50 mcg
Copper (Copper Bisglycinate)
1 mg 90
Manganese (Manganese Bisglycinate)
5 mg 96
Chromium (Chromium Picolinate)
100 mcg 53
Molybdenum (Sodium Molybdate)
50 mcg 64
Potassium (Potassium Chloride)
50 mg
Choline (Choline Bitartrate)
50 mg 55
Inositol
50 mg
PABA
30 mg 78
organic Spirulina
400 mg 53
Chlorella
50 mg
Alfalfa juice concentrate
50 mg
Alpha Lipoic Acid
50 mg
Green Tea extract
50 mg 8
Milk Thistle extract (Silymarin)
50 mg 16
Rutin powder (Sophora japonica)
25 mg 83
Alfalfa
4 mg
organic Rose Hip powder
4 mg
Lutein (Marigold flowers extract)
250 mcg
Lycopene (natural Tomato extract)
250 mcg
Amylase
10 mg
Lipase
10 mg
Bromelain (Pineapple)
20 mg 47
Papain
25 mg 96
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value
Each serving provides 5 mg of manganese at a moderate cost per serving. The amount falls within the stated range for bone and joint support. The manganese comes as manganese bisglycinate, an amino acid chelate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

The manganese comes as manganese bisglycinate, an amino acid chelate.
Manganese Chemical Form
The manganese comes as manganese bisglycinate, an amino acid chelate.

Dose, Safety & Label Transparency100

5 mg falls within the stated range for bone and joint support. The label states both the manganese amount and its source.
Manganese Dosage Efficacy & Safety
5 mg falls within the stated range for bone and joint support.
Elemental Weight Disclosure
The label states both the manganese amount and its source.

Value80

The cost per serving is moderate.
Price per Serving vs. Median
The cost per serving is moderate.
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value
The serving supplies 150 mcg iodine. The cost per serving is relatively low. The iodine comes from potassium iodide. The amount is clearly stated.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

The iodine comes from potassium iodide. No marine source is indicated, so seaweed purity markers do not apply.
Iodine Form & Bioavailability
The iodine comes from potassium iodide.
Marine Source Purity & Sourcing
No marine source is indicated, so seaweed purity markers do not apply.

Dose, Safety & Label Transparency100

The serving supplies 150 mcg iodine. The iodine amount and source are stated.
Dosage Efficacy for Daily Support
The serving supplies 150 mcg iodine.
Dosage Safety & Upper Limits
The 150 mcg serving is below the adult upper intake limit.
Elemental Iodine Transparency
The iodine amount and source are stated.

Value80

The cost per serving is relatively low.
Price Per Effective Serving
The cost per serving is relatively low.
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB+ Value
The serving provides 1 mg of copper at a moderate cost per serving. The amount is clearly stated. It uses Copper Bisglycinate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

Copper Bisglycinate is the named source, and the label states the elemental copper amount.
Copper Form Bioavailability
The label names Copper Bisglycinate as the copper source.
Elemental Copper Labeling Clarity
The label identifies Copper Bisglycinate and states 1 mg of elemental copper.

Dose, Safety & Label Transparency86

The serving provides 1 mg of copper. The serving also contains 15 mg of zinc, a zinc-to-copper ratio of about 15:1.
Copper Dosage Safety & Efficacy
The serving provides 1 mg of copper.
Zinc-to-Copper Balance
The serving also contains 15 mg of zinc, a zinc-to-copper ratio of about 15:1.

Value80

The cost per serving is moderate.
Price Per Serving Efficiency
The cost per serving is moderate.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  2. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  3. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  4. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  5. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  6. The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
    Ju Y; Xiong W; Pang Y; Chen Z; Hou J; Zheng S; Li Z; Liu T; Xia H; Xia M; Zhong Y; Li J; Jiang X · Biological trace element research · 2026
    Scoping review18 studies pooledBone Health forCopper
  7. Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
    Chen M; Jia L; Gao R · Frontiers in nutrition · 2024
    Cohort study5,286 participantsBone Health forCopper
  8. Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
    Hu M; Wang Z; Li C; Zheng Y; Hu J · Medicine · 2025
    Cross-sectional studyBone Health forCopper
  9. The association between dietary mineral intake and bone mineral density: a cross-sectional study.
    Wei M; Wei J; Huang S · Journal of health, population, and nutrition · 2025
    Cross-sectional study11,520 participantsBone Health forCopper
  10. Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
    Cui A; Yan J; Li H; Fan Z; Wei X; Wang H; Zhuang Y · PloS one · 2024
    Cross-sectional study6,965 participantsBone Health forCopper
  11. Association between RBC folate and lumbar bone mineral density in postmenopausal women, a cross-sectional study from NHANES 2009-2018.
    Wei H; Jin Z; Zhou L; Tang G; Chai S; Che X; Tan Y; Zeng W · Frontiers in endocrinology · 2025
    Cross-sectional study1,315 participantsBone Health forFolate
  12. Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density.
    Liu CT; Karasik D; Xu H; Zhou Y; Broe K; Cupples LA; Cpgm de Groot L; Ham A; Hannan MT; Hsu YH; Jacques P; McLean RR; Paul L; Selhub J; Trajanoska K; van der Velde N; van Schoor N; Kiel DP · The American journal of clinical nutrition · 2021
    Cohort study4,310 participantsBone Health forFolate
  13. Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
    Rondanelli M; Tartara A; Fossari F; Vecchio V; Faliva MA; Naso M; Perna S; Nichetti M; Peroni G · Current aging science · 2022
    Narrative review35,298 participants29 studies pooledBone Health forFolate Bone Health forVitamin B6
  14. Relation of homocysteine, folate, and vitamin B12 to bone mineral density of postmenopausal women.
    Cagnacci A; Baldassari F; Rivolta G; Arangino S; Volpe A · Bone · 2004
    Cross-sectional study161 participantsBone Health forFolate
  15. Dietary intake of folate, but not vitamin B2 or B12, is associated with increased bone mineral density 5 years after the menopause: results from a 10-year follow-up study in early postmenopausal women.
    Rejnmark L; Vestergaard P; Hermann AP; Brot C; Eiken P; Mosekilde L · Calcified tissue international · 2008
    Cohort study1,869 participantsBone Health forFolate
  16. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  17. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  18. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  19. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  20. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium