$52.00 $0.57 per serving
Product analysis
The Big One with Iron supplies nutrients for normal energy use, blood formation and immune function when dietary intake falls short. Missing proportions for several mixed forms make detailed comparisons less straightforward.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality57
Several B vitamins and minerals have clearly identified forms with favorable quality characteristics. Other ingredients remain less certain, and missing proportions limit a clear judgment about the mixed forms.
Ingredient Transparency76
Ingredient amounts and most forms are disclosed. The proportions of several mixed forms are missing, making the exact composition harder to compare.
Value For Money41
Value is mixed across the nutrients, with favorable costs for vitamin K and molybdenum but weak value for several others. Uncertain value for a number of ingredients limits a confident judgment about the whole combination.
Customer Satisfaction73
The available customer ratings are very positive. The relatively small number of ratings gives a narrower satisfaction picture than a widely reviewed product.
Product Focus35
The clearest role is covering nutritional shortfalls, including nutrients involved in blood formation. Its broad ingredient list and many proposed uses make it less focused on a single need.
- Format
Capsule - Container
- 90 Capsule(s)
- Per serving
- $0.57
- Customer rating
- 4.8 · 100 ratings
Goals
Impact
Highest effect
Vitamin C · 125 mgZinc · 15 mgVitamin A · 2400 mcg RAEVitamin D · 25 mcgSelenium · 100 mcg
Zinc, vitamin D and selenium support normal immune function, while vitamin A contributes to barrier nutrition. Copper, iron, B6, B12 and folate can help restore immune-cell function when intake is low. These nutritional roles do not establish infection prevention in people with adequate intake. Vitamin E receives saved credit despite mixed, population-specific outcome evidence, and the vitamin C amount did not qualify in the saved findings.
How this product is rated for Immunity
Ingredient fit64
The nutrient mix covers several immune roles, although many other actives broaden its focus.
Goal fit
Relevant immune nutrients share the formula with numerous actives outside the assessed goal.
Dose adequacy
Many credited amounts are substantial, while vitamin C falls below the saved contribution threshold.
Pathways100
Barrier and antimicrobial defense is the strongest covered area. Barrier defense, immune regulation and oxidative balance reach substantial coverage.
Depth
Barrier and antimicrobial defense has the strongest combined coverage.
Breadth
Barrier defense, immune regulation and oxidative balance reach substantial coverage.
Evidence100
Zinc leads the saved support finding. Credited preparations meet the saved criteria, within the specific evidence limits described for their roles.
Evidence strength
Zinc provides the strongest saved support; that position does not establish a probability of protection.
Studied preparation
Credited preparations meet the saved criteria, without establishing superiority of individual nutrient forms.
Formulation logic100
Credited ingredients clear the saved amount threshold and have no assessed missing partner or conflict.
Partner coverage
Credited ingredients work alone or have their relevant partners.
Conflicts
No assessed ingredient conflict was triggered.
Effective doses
All credited ingredients clear the saved minimum amount threshold, which is not proof of clinical effectiveness.
Impact
Highest effect
Folate · 667 mcg DFEVitamin B12 · 100 mcgVitamin D · 25 mcgVitamin K · 100 mcgBoron · 1 mgSelenium · 100 mcgZinc · 15 mgVitamin C · 125 mg
B vitamins contribute to energy metabolism, while folate, vitamin B12 and iron support blood formation. Vitamin D and vitamin K add bone nutrition, with zinc and selenium contributing to normal immune and antioxidant functions. Iodine provides nutritional support when intake is low. These roles concern filling dietary gaps; the formula does not establish additional benefit when intake is adequate.
How this product is rated for Everyday Health
Ingredient fit79
B vitamins, folate, iron, iodine, vitamins D and K, zinc and selenium provide the relevant nutritional contributions within a broader formula. Nutrient amounts vary, with several reaching the comparison range.
Goal fit
B vitamins, folate, iron, iodine, vitamins D and K, zinc and selenium provide the relevant nutritional contributions within a broader formula.
Dose adequacy
Nutrient amounts vary, with several reaching the comparison range.
Pathways100
The supported coverage includes energy metabolism, blood formation, bone and mineral metabolism, and antioxidant and immune defence.
Depth
The strongest contribution centres on energy metabolism, blood formation, bone and mineral metabolism, and antioxidant and immune defence.
Breadth
The supported coverage includes energy metabolism, blood formation, bone and mineral metabolism, and antioxidant and immune defence.
Evidence82
Folate provides the strongest supported contribution at the supplied amount. The relevant preparations were accepted, without establishing superiority of a particular form.
Evidence strength
Folate provides the strongest supported contribution at the supplied amount, within the limits of its nutritional role.
Studied preparation
The relevant preparations were accepted in the supplied findings; this does not establish a special benefit from their forms.
Formulation logic100
The included nutrient contributions meet the saved amount criterion; this is not proof of additional health benefit.
Partner coverage
The included contributions do not have an unmet required ingredient partner.
Conflicts
No listed ingredient conflict was identified in the supplied findings.
Effective doses
The included nutrient contributions meet the saved amount criterion; this is not proof of additional health benefit.
Impact
High effect
Biotin · 200 mcgNiacin · 100 mg NEVitamin B12 · 100 mcgRiboflavin · 25 mgThiamin · 25 mgVitamin B5 · 100 mgVitamin B6 · 25 mgVitamin D · 25 mcgZinc · 15 mg
B vitamins help the body carry out normal energy metabolism. Taking extra amounts does not establish increased energy expenditure when nutrient intake is adequate. Iodine supports thyroid hormone production, so correcting low iodine intake can address a cause of reduced metabolic rate. Iron can help restore impaired heat production when iron-deficiency anaemia is present.
How this product is rated for Metabolism Support
Ingredient fit70
The formula contributes nutrients involved in normal metabolism. Its mix and disclosed amounts determine the saved ingredient findings.
Goal fit
The formula has counted nutritional contributions alongside ingredients serving broader purposes.
Dose adequacy
The counted amounts partly meet the saved references; unknown amounts cannot establish a contribution comparable with studied exposures.
Pathways4
The main recorded contribution concerns insulin sensitivity and metabolic hormones; this does not by itself demonstrate increased whole-body energy use.
Depth
The main recorded contribution concerns insulin sensitivity and metabolic hormones; this does not by itself demonstrate increased whole-body energy use.
Breadth
No evaluated pathway reached the coverage criterion.
Evidence100
The saved evidence comparison accepts nutrient or cellular roles, while the supplied scientific context limits claims of increased energy expenditure.
Evidence strength
Vitamin B1 (Thiamin) leads the saved evidence comparison, but its physiological role or metabolic-marker findings do not establish a routine increase in energy expenditure.
Studied preparation
The counted preparations meet the saved preparation comparison; this does not prove a particular form raises metabolic rate more effectively.
Formulation logic100
There are no unmet partner requirements or configured conflicts. The amount findings describe the counted ingredients, without establishing combined metabolic benefits.
Partner coverage
No counted ingredient has an unmet partner requirement in the supplied findings.
Conflicts
No configured ingredient conflict was triggered.
Effective doses
All counted ingredients meet the saved minimum amount criterion, which is not proof of increased metabolic rate.
Impact
High effect
Biotin · 200 mcgVitamin D · 25 mcgZinc · 15 mgIron · 10 mgVitamin C · 125 mg
Zinc can help address diffuse shedding linked to low zinc intake, while iron can serve a similar role when iron deficiency is involved. Vitamin C supports normal collagen synthesis and iron absorption, though these functions do not establish independent hair regrowth. Copper contributes to pigmentation and connective-tissue biology without proving routine regrowth. Selenium and vitamin A have normal biological roles, but excess intake of either can contribute to hair loss.
How this product is rated for Hair Health
Ingredient fit64
The formula combines hair-related nutrients with broader nutritional ingredients. Their amounts vary in how closely they meet the supplied comparison anchors.
Goal fit
Hair-related nutrients are present alongside other actives, so the formula has a broader nutritional focus.
Dose adequacy
Declared amounts provide partial support against the supplied comparison anchors, which are not proven hair-growth doses.
Pathways60
The strongest recorded contribution concerns antioxidant protection around follicles; this does not establish improved hair growth.
Depth
The strongest recorded contribution concerns antioxidant protection around follicles; this does not establish improved hair growth.
Breadth
Antioxidant protection is the only pathway reaching the supplied coverage criterion; androgen and stress effects are not established.
Evidence97
Zinc provides the strongest supported link here, particularly for shedding associated with zinc deficiency.
Evidence strength
Zinc provides the strongest supported link here, particularly for shedding associated with zinc deficiency.
Studied preparation
Most qualifying preparations match the supplied comparison; iodine does not have a matching studied preparation.
Formulation logic100
Partner requirements are met, no configured conflict is identified, and counted ingredients meet the saved minimum amount criterion.
Partner coverage
The included ingredients have no unmet partner requirement in the supplied findings; this does not establish added benefit from combining them.
Conflicts
No configured ingredient conflict was identified in the supplied findings.
Effective doses
All counted ingredients meet the saved minimum amount criterion, which is a comparison threshold rather than a proven hair-growth dose.
Impact
Moderate effect
Iodine · 100 mcgVitamin D · 25 mcgVitamin B5 · 100 mgRiboflavin · 25 mgThiamin · 25 mgVitamin B12 · 100 mcgIron · 10 mg
B vitamins and folate support normal metabolism and blood formation, while vitamin C and 10 mg of iron contribute toward nutritional needs relevant to fatigue. Iron is most relevant when intake or stores are inadequate; deficiency is not assumed. High vitamin amounts and the small vanadium declaration do not establish additional energy benefits.
How this product is rated for Energy
Ingredient fit63
The saved assessment identifies 10 goal-related ingredients alongside 11 other actives, so the formula serves a broader purpose than energy support alone. The saved amount assessment considers 10 ingredients; undisclosed individual amounts limit the contribution that can be assigned.
Goal fit
The saved assessment identifies 10 goal-related ingredients alongside 11 other actives, so the formula serves a broader purpose than energy support alone.
Dose adequacy
The saved amount assessment considers 10 ingredients; undisclosed individual amounts limit the contribution that can be assigned.
Pathways0
The saved findings identify no coverage of the listed direct energy mechanisms; the relevant contribution is nutritional. No reviewed energy mechanism reaches the saved level for substantial coverage.
Depth
The saved findings identify no coverage of the listed direct energy mechanisms; the relevant contribution is nutritional.
Breadth
No reviewed energy mechanism reaches the saved level for substantial coverage.
Evidence97
The saved evidence finding is led by Iron, among ingredients meeting the assessment’s amount requirement; this does not imply uniform energy benefit. Preparation matching is incomplete for Iodine; findings for a specific material should not be transferred automatically.
Evidence strength
The saved evidence finding is led by Iron, among ingredients meeting the assessment’s amount requirement; this does not imply uniform energy benefit.
Studied preparation
Preparation matching is incomplete for Iodine; findings for a specific material should not be transferred automatically.
Formulation logic100
The saved findings identify no missing required partner among the assessed ingredients. No configured ingredient conflict was identified in the saved assessment. 10 of 10 credited ingredients meet the saved minimum amount criterion.
Partner coverage
The saved findings identify no missing required partner among the assessed ingredients.
Conflicts
No configured ingredient conflict was identified in the saved assessment.
Effective doses
10 of 10 credited ingredients meet the saved minimum amount criterion.
Vitamin B5 Not classified
No linked studies yet.
Impact
High effect
Folate · 667 mcg DFEVitamin B12 · 100 mcgVitamin B6 · 25 mgMolybdenum · 50 mcgSelenium · 100 mcgVitamin E · 67 mgZinc · 15 mgVitamin C · 125 mgRiboflavin · 25 mg
Folate and selenium can help address low intake, with toxin-related findings limited to folic acid in arsenic-exposed populations and particular selenium preparations in small mercury studies. Those results do not establish general toxin removal, and this product's forms do not all establish equivalence to those preparations. Its broader nutrient roles support normal metabolism without proving extra clearance when intake is adequate.
How this product is rated for Liver & Detox
Ingredient fit59
Folate and selenium provide the conditional nutritional connections within a broad vitamin and mineral formula.
Goal fit
Folate and selenium provide the conditional nutritional connections within a broad vitamin and mineral formula.
Dose adequacy
The qualifying nutrients contribute to the saved amount finding; vitamin C is below the counting threshold.
Pathways64
Methyl-group supply leads the saved findings.
Depth
Methyl-group supply leads the saved findings.
Breadth
Methyl-group supply and enzyme-related processes are substantially represented.
Evidence97
Folate leads the saved evidence finding. Molybdenum, riboflavin and vitamin B6 lack the saved studied-preparation finding.
Evidence strength
Folate leads the saved evidence finding; the supplied context limits what can be concluded about routine toxin clearance.
Studied preparation
Molybdenum, riboflavin and vitamin B6 lack the saved studied-preparation finding.
Formulation logic100
All eight credited ingredients meet the saved amount threshold. No configured conflict was identified.
Partner coverage
Every credited ingredient works alone or has its required partner in the saved findings.
Conflicts
No configured ingredient conflict was identified in the saved findings.
Effective doses
All eight credited ingredients meet the saved amount threshold.
Riboflavin Not classified
No linked studies yet.
Vitamin B6 Not classified
No linked studies yet.
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
Vitamin A (Natural Mixed Carotenoids, Vitamin A Palmitate) | 2400 mcg RAE | |
Vitamin C (Ascorbic Acid, Ascorbyl Palmitate) | 125 mg | |
Vitamin D3 (Cholecalciferol) | 25 mcg | |
Vitamin E (D-Alpha-Tocopheryl Acid Succinate, Mixed Tocopherols) | 67 mg | |
Vitamin K (Vitamin K1, Vitamin K2) | 100 mcg | |
Thiamine (Thiamine Mononitrate) | 25 mg | |
Riboflavin (Riboflavin 5-Phosphate) | 25 mg | |
Niacin (Niacinamide) | 100 mg NE | |
Vitamin B6 (Pyridoxal 5-Phosphate, Pyridoxine Hydrochloride) | 25 mg | |
Folate (Calcium Salt, L-5-Methylfolate) | 667 mcg DFE | |
Vitamin B12 (Methylcobalamin) | 100 mcg | |
Biotin | 200 mcg | |
Pantothenic Acid (Calcium D-Pantothenate) | 100 mg | |
Iron (Iron Bisglycinate) | 10 mg | |
Iodine (Potassium Iodide) | 100 mcg | |
Zinc (Zinc Citrate) | 15 mg | |
Selenium (L-Selenomethionine) | 100 mcg | |
Copper (Copper Gluconate) | 1 mg | |
Manganese (Manganese Glycinate) | 5 mg | |
Chromium (Chromium Polynicotinate) | 100 mcg | |
Molybdenum (Molybdenum Glycinate) | 50 mcg | |
Betaine HCl | 25 mg | |
Boron (Boron Citrate) | 1 mg | |
Vanadium (Vanadyl Sulfate) | 50 mcg |
A serving contains 25 mg of vitamin B6, exceeding the European adult daily upper limit. The B6 is identified as Pyridoxal 5-Phosphate and Pyridoxine Hydrochloride, and B6 from food or other supplements adds to the daily total.
How this ingredient is rated
Ingredient Form & Label Quality100
The vitamin B6 source is identified as Pyridoxal 5-Phosphate and Pyridoxine Hydrochloride. The proportions of the two forms are not disclosed. The recorded check found no artificial dyes, titanium dioxide or talc.
Vitamin B6 Form Identification
The B6 source is identified as Pyridoxal 5-Phosphate and Pyridoxine Hydrochloride. The proportions of the two forms are not disclosed.
Clean Label and Excipient Purity
The recorded check found no artificial dyes, titanium dioxide or talc.
Dose, Safety & Label Transparency60
The 25 mg of B6 per serving exceeds the European adult daily upper limit; other sources also contribute to daily intake. The label identifies Pyridoxal 5-Phosphate and Pyridoxine Hydrochloride as the source.
Vitamin B6 Dose & Safety Policy
The 25 mg of B6 per serving exceeds the European adult daily upper limit; other sources also contribute to daily intake.
Label Transparency
The B6 source is disclosed as Pyridoxal 5-Phosphate and Pyridoxine Hydrochloride.
Value68
The whole-product serving costs about $0.58 for 25 mg of B6, a moderate cost per mg in the comparison.
Vitamin B6 Price Efficiency
The whole-product serving costs about $0.58 for 25 mg of B6, a moderate cost per mg in the comparison.
Manganese (Manganese Glycinate) · 5 mg OverallScore79
A serving lists 5 mg of manganese as glycinate and gluconate. The amounts supplied by each form are not known.
How this ingredient is rated
Active Ingredient Quality & Bioavailability72
Manganese glycinate and gluconate are listed, but the amount from each form is unknown.
Manganese Chemical Form
Manganese glycinate and gluconate are listed, but the amount from each form is unknown.
Dose, Safety & Label Transparency100
A serving lists 5 mg of elemental manganese.
Manganese Dosage Efficacy & Safety
The declared serving contains 5 mg of manganese.
Elemental Weight Disclosure
The elemental manganese amount is declared as 5 mg per serving.
Value50
About $0.58 per whole-product serving covers the entire product, not manganese alone.
Price per Serving vs. Median
The price comparison uses about $0.58 per whole-product serving.
Selenium (L-Selenomethionine) · 100 mcg OverallScore77
A serving provides 100 mcg of selenium as l-selenomethionine. At the listed price, the product costs about $1.16 per 200 mcg of selenium for comparison.
How this ingredient is rated
Active Ingredient Quality & Bioavailability100
The selenium is identified as L-selenomethionine, with the L form specifically named.
Selenium Chemical Form
The recorded form is L-selenomethionine, an organic form of selenium.
Form Transparency & Isomer Specificity
The name specifies the L form of selenomethionine.
Dose, Safety & Label Transparency88
The serving provides 100 mcg of selenium. It falls below the upper limit used in the evaluation, though food and other sources also contribute to total intake.
Dosage Efficacy Sweet Spot
A serving supplies 100 mcg of selenium, an amount used for selenium support.
Safety Margin & UL Adherence
The 100 mcg in a serving is below the upper limit used in the evaluation; food and other products also contribute to total selenium intake.
Value10
At the listed price, about $1.16 of the whole product corresponds to 200 mcg of selenium. The cost also covers any other ingredients.
Price per 200 mcg Serving
At the listed price, about $1.16 of the whole product corresponds to 200 mcg of selenium. The cost also covers any other ingredients.
Alternative products
Report alternatives
Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
- Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
- The relationship between boron and magnesium status and bone mineral density in the human: a review.
- Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
- Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
- The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
- Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
- Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
- The association between dietary mineral intake and bone mineral density: a cross-sectional study.
- Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
- Association between RBC folate and lumbar bone mineral density in postmenopausal women, a cross-sectional study from NHANES 2009-2018.
- Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density.
- Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
- Relation of homocysteine, folate, and vitamin B12 to bone mineral density of postmenopausal women.
- Dietary intake of folate, but not vitamin B2 or B12, is associated with increased bone mineral density 5 years after the menopause: results from a 10-year follow-up study in early postmenopausal women.
- Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES.
- The Manganese-Bone Connection: Investigating the Role of Manganese in Bone Health.
- Associations of multiple metals with bone mineral density: A population-based study in US adults.
- Sex-specific associations of urinary mixed-metal concentrations with femoral bone mineral density among older people: an NHANES (2017-2020) analysis.
- Relationship between blood manganese and bone mineral density and bone mineral content in adults: A population-based cross-sectional study.