The Big One without Iron
Goals
$48.00 $0.53 per serving
Product analysis
The Big One without Iron offers broad vitamin and mineral support for normal immune function, energy use and blood formation when intake is low. Several blend proportions are undisclosed, so the label does not show exactly how much of each form you receive.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality57
Several B vitamins, selenium, chromium and molybdenum use favorable forms. Unspecified forms and incomplete blends leave other parts of the formula harder to compare.
Ingredient Transparency76
Nutrient amounts and most forms are listed clearly. Missing proportions in several blends prevent a precise comparison of the amounts of each form.
Value For Money42
Value varies substantially between nutrients, with vitamin K and molybdenum among the more favorable parts. Selenium, chromium, boron and B5 are costly when considered at the full serving price.
Customer Satisfaction79
Customer ratings are generally positive. Several hundred customer ratings provide a useful picture of satisfaction.
Product Focus37
The formula covers broad nutritional needs rather than one narrowly defined purpose. Its clearest benefits come from correcting low intake, and larger amounts do not establish extra everyday energy.
- Format
Capsule - Container
- 90 Capsule(s)
- Per serving
- $0.53
- Customer rating
- 4.7 · 867 ratings
Goals
Impact
High effect
Biotin · 200 mcgNiacin · 100 mg NEVitamin B12 · 100 mcgRiboflavin · 25 mgThiamin · 25 mgVitamin B5 · 100 mgVitamin B6 · 25 mgVitamin D · 25 mcgZinc · 15 mg
B vitamins help the body carry out normal energy metabolism. Taking extra amounts does not establish increased energy expenditure when nutrient intake is adequate. Iodine supports thyroid hormone production, so correcting low iodine intake can address a cause of reduced metabolic rate.
How this product is rated for Metabolism Support
Ingredient fit70
The formula contributes nutrients involved in normal metabolism. Its mix and disclosed amounts determine the saved ingredient findings.
Goal fit
The formula has counted nutritional contributions alongside ingredients serving broader purposes.
Dose adequacy
The counted amounts partly meet the saved references; unknown amounts cannot establish a contribution comparable with studied exposures.
Pathways4
The main recorded contribution concerns insulin sensitivity and metabolic hormones; this does not by itself demonstrate increased whole-body energy use.
Depth
The main recorded contribution concerns insulin sensitivity and metabolic hormones; this does not by itself demonstrate increased whole-body energy use.
Breadth
No evaluated pathway reached the coverage criterion.
Evidence100
The saved evidence comparison accepts nutrient or cellular roles, while the supplied scientific context limits claims of increased energy expenditure.
Evidence strength
Vitamin B1 (Thiamin) leads the saved evidence comparison, but its physiological role or metabolic-marker findings do not establish a routine increase in energy expenditure.
Studied preparation
The counted preparations meet the saved preparation comparison; this does not prove a particular form raises metabolic rate more effectively.
Formulation logic100
There are no unmet partner requirements or configured conflicts. The amount findings describe the counted ingredients, without establishing combined metabolic benefits.
Partner coverage
No counted ingredient has an unmet partner requirement in the supplied findings.
Conflicts
No configured ingredient conflict was triggered.
Effective doses
All counted ingredients meet the saved minimum amount criterion, which is not proof of increased metabolic rate.
Impact
Highest effect
Vitamin C · 125 mgZinc · 15 mgVitamin A · 2400 mcg RAEVitamin D · 25 mcgSelenium · 100 mcg
Zinc, vitamin D and selenium contribute to normal immune function, while vitamin A supports barrier nutrition. Copper, B6, B12 and folate can help fill dietary gaps that impair immune-cell function. These roles do not establish infection prevention when intake is adequate. Vitamin E receives saved credit despite mixed findings in specific older populations, and vitamin C did not qualify at its declared amount.
How this product is rated for Immunity
Ingredient fit63
A broad nutrient mix covers several immune roles, with many other actives reducing focus.
Goal fit
The immune nutrients share the formula with numerous actives outside the assessed goal.
Dose adequacy
Most credited amounts contribute substantially, while vitamin C falls below the saved contribution threshold.
Pathways100
Barrier and antimicrobial defense is the strongest covered area. Barrier defense, immune regulation and oxidative balance reach substantial coverage.
Depth
Barrier and antimicrobial defense has the strongest combined coverage.
Breadth
Barrier defense, immune regulation and oxidative balance reach substantial coverage.
Evidence100
Zinc leads the saved support finding. Credited preparations meet the saved criteria, within the specific evidence limits described for their roles.
Evidence strength
Zinc provides the strongest saved support; that position does not establish a probability of protection.
Studied preparation
Credited preparations meet the saved criteria, without establishing superiority of individual nutrient forms.
Formulation logic100
Credited ingredients clear the saved amount threshold and have no assessed missing partner or conflict.
Partner coverage
Credited ingredients work alone or have their relevant partners.
Conflicts
No assessed ingredient conflict was triggered.
Effective doses
All credited ingredients clear the saved minimum amount threshold, which is not proof of clinical effectiveness.
Impact
Moderate effect
Iodine · 100 mcgVitamin D · 25 mcgVitamin B5 · 100 mgRiboflavin · 25 mgThiamin · 25 mgVitamin B12 · 100 mcg
Thiamin, riboflavin, niacin, B5 and B6 provide the main connection to normal energy metabolism. Folate and vitamin C also help cover nutritional needs associated with tiredness when intake is inadequate. Extra energy above adequacy is not established by the high vitamin amounts, and the small vanadium amount adds no supported routine benefit.
How this product is rated for Energy
Ingredient fit67
The saved assessment identifies 9 goal-related ingredients alongside 11 other actives, so the formula serves a broader purpose than energy support alone. The saved amount assessment considers 9 ingredients; undisclosed individual amounts limit the contribution that can be assigned.
Goal fit
The saved assessment identifies 9 goal-related ingredients alongside 11 other actives, so the formula serves a broader purpose than energy support alone.
Dose adequacy
The saved amount assessment considers 9 ingredients; undisclosed individual amounts limit the contribution that can be assigned.
Pathways0
The saved findings identify no coverage of the listed direct energy mechanisms; the relevant contribution is nutritional. No reviewed energy mechanism reaches the saved level for substantial coverage.
Depth
The saved findings identify no coverage of the listed direct energy mechanisms; the relevant contribution is nutritional.
Breadth
No reviewed energy mechanism reaches the saved level for substantial coverage.
Evidence94
The saved evidence finding is led by Vitamin D, among ingredients meeting the assessment’s amount requirement; this does not imply uniform energy benefit. Preparation matching is incomplete for Iodine; findings for a specific material should not be transferred automatically.
Evidence strength
The saved evidence finding is led by Vitamin D, among ingredients meeting the assessment’s amount requirement; this does not imply uniform energy benefit.
Studied preparation
Preparation matching is incomplete for Iodine; findings for a specific material should not be transferred automatically.
Formulation logic100
The saved findings identify no missing required partner among the assessed ingredients. No configured ingredient conflict was identified in the saved assessment. 9 of 9 credited ingredients meet the saved minimum amount criterion.
Partner coverage
The saved findings identify no missing required partner among the assessed ingredients.
Conflicts
No configured ingredient conflict was identified in the saved assessment.
Effective doses
9 of 9 credited ingredients meet the saved minimum amount criterion.
Vitamin B5 Not classified
No linked studies yet.
Impact
Highest effect
Folate · 667 mcg DFEVitamin B12 · 100 mcgVitamin D · 25 mcgVitamin K · 100 mcgBoron · 1 mgSelenium · 100 mcgZinc · 15 mgVitamin C · 125 mg
B vitamins contribute to energy metabolism, folate and vitamin B12 support blood formation, and iodine supplies nutritional support when intake is low. Vitamins D and K add bone nutrition, while zinc and selenium contribute to normal immune and antioxidant functions. The smaller vitamin C and boron amounts were not counted. These nutritional roles do not establish added benefit when intake is already adequate.
How this product is rated for Everyday Health
Ingredient fit79
B vitamins, folate, iodine, vitamins D and K, zinc and selenium provide the relevant nutritional contributions within a broader formula. Nutrient amounts vary, with several reaching the comparison range.
Goal fit
B vitamins, folate, iodine, vitamins D and K, zinc and selenium provide the relevant nutritional contributions within a broader formula.
Dose adequacy
Nutrient amounts vary, with several reaching the comparison range.
Pathways100
The supported coverage includes energy metabolism, blood formation, bone and mineral metabolism, and antioxidant and immune defence.
Depth
The strongest contribution centres on energy metabolism, blood formation, bone and mineral metabolism, and antioxidant and immune defence.
Breadth
The supported coverage includes energy metabolism, blood formation, bone and mineral metabolism, and antioxidant and immune defence.
Evidence82
Folate provides the strongest supported contribution at the supplied amount. The relevant preparations were accepted, without establishing superiority of a particular form.
Evidence strength
Folate provides the strongest supported contribution at the supplied amount, within the limits of its nutritional role.
Studied preparation
The relevant preparations were accepted in the supplied findings; this does not establish a special benefit from their forms.
Formulation logic100
The included nutrient contributions meet the saved amount criterion; this is not proof of additional health benefit.
Partner coverage
The included contributions do not have an unmet required ingredient partner.
Conflicts
No listed ingredient conflict was identified in the supplied findings.
Effective doses
The included nutrient contributions meet the saved amount criterion; this is not proof of additional health benefit.
Impact
High effect
Vitamin K · 100 mcgVitamin B12 · 100 mcgVitamin B6 · 25 mgFolate · 667 mcg DFEVitamin D · 25 mcg
Folate and related B vitamins support homocysteine metabolism, but lowering this marker has not generally prevented major cardiac events. Thiamin supports heart function when deficiency is responsible for disease; adequate intake does not imply further benefit. Selenium is relevant to deficiency-related heart disease, without established prevention benefits in adequately nourished adults.
How this product is rated for Heart Health
Ingredient fit61
Vitamin B9 (Folate), Vitamin B6, Vitamin B12, Selenium, Vitamin D, Vitamin B1 (Thiamin) provide the main connection to heart health; other active ingredients broaden the formula beyond this goal
Goal fit
Vitamin B9 (Folate), Vitamin B6, Vitamin B12, Selenium, Vitamin D, Vitamin B1 (Thiamin) provide the main connection to heart health; other active ingredients broaden the formula beyond this goal
Dose adequacy
The relevant amounts provide a partial contribution across the formula; higher amounts are not automatically more beneficial.
Pathways60
Homocysteine clearance is the strongest connection in the saved findings; this describes the ingredient roles, not a guaranteed effect.
Depth
Homocysteine clearance is the strongest connection in the saved findings; this describes the ingredient roles, not a guaranteed effect.
Breadth
The main areas represented are homocysteine clearance; other aspects have less support in this formula.
Evidence89
Vitamin B9 (Folate) provides the strongest relevant evidence here, with the population and benefit limits described above.
Evidence strength
Vitamin B9 (Folate) provides the strongest relevant evidence here, with the population and benefit limits described above.
Studied preparation
The contributing ingredient preparations match those recognized in the supplied comparison; this does not establish efficacy of the finished product.
Formulation logic100
The relevant ingredients do not depend on a missing partner in the supplied findings. No configured ingredient conflict was identified in the supplied findings.
Partner coverage
The relevant ingredients do not depend on a missing partner in the supplied findings.
Conflicts
No configured ingredient conflict was identified in the supplied findings.
Effective doses
The contributing ingredients have meaningful declared amounts for comparison, without proving a cardiovascular benefit.
Impact
High effect
Zinc · 15 mgVitamin E · 67 mgVitamin C · 125 mgCopper · 1 mgVitamin A · 2400 mcg RAE
Vitamin A supports the visual cycle and can address impaired dark adaptation caused by deficiency; extra vision benefit with adequate intake is unestablished. Riboflavin also has a deficiency-related eye role. Zinc and antioxidant vitamins have evidence tied to specific AMD combinations, while copper's role there is formulation balance rather than independent vision improvement.
How this product is rated for Eye Health
Ingredient fit54
Several nutrients receive credit within a wider formula serving other goals.
Goal fit
Several nutrients receive credit within a wider formula serving other goals.
Dose adequacy
The declared amounts contribute unevenly; reaching an amount threshold does not establish a routine visual benefit.
Pathways60
Coverage is concentrated in antioxidant support for the retina and lens; other tracked areas remain limited or uncovered.
Depth
Retinal and lens antioxidant support receives the strongest assigned coverage, without demonstrating improved vision.
Breadth
Only retinal and lens antioxidant support reaches the coverage threshold.
Evidence88
Copper carries the strongest assigned evidence weight, although its AREDS role is balancing zinc rather than independently improving vision.
Evidence strength
Copper carries the strongest assigned evidence weight, although its AREDS role is balancing zinc rather than independently improving vision.
Studied preparation
The credited preparations are recognized in the saved findings; this does not establish a complete clinical regimen or universal form equivalence.
Formulation logic100
Credited ingredients have no missing required partner, and no configured ingredient conflict was identified.
Partner coverage
Every credited ingredient works independently or has its required partner in the saved finding.
Conflicts
No configured ingredient conflict was identified.
Effective doses
Every credited ingredient meets the comparison's amount threshold; this is not proof of a clinically effective vision dose.
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
Vitamin A (Natural Mixed Carotenoids, Vitamin A Palmitate) | 2400 mcg RAE | |
Vitamin C (Ascorbic Acid, Ascorbyl Palmitate) | 125 mg | |
Vitamin D3 (Cholecalciferol) | 25 mcg | |
Vitamin E (D-Alpha-Tocopheryl Acid Succinate, Mixed Tocopherols) | 67 mg | |
Vitamin K (Vitamin K1, Vitamin K2) | 100 mcg | |
Thiamine (Thiamine Mononitrate) | 25 mg | |
Riboflavin (Riboflavin 5-Phosphate) | 25 mg | |
Niacin (Niacinamide) | 100 mg NE | |
Vitamin B6 (Pyridoxal 5-Phosphate, Pyridoxine Hydrochloride) | 25 mg | |
Folate (Calcium Salt, L-5-Methylfolate) | 667 mcg DFE | |
Vitamin B12 (Methylcobalamin) | 100 mcg | |
Biotin | 200 mcg | |
Pantothenic Acid (Calcium D-Pantothenate) | 100 mg | |
Iodine (Potassium Iodide) | 100 mcg | |
Zinc (Zinc Citrate) | 15 mg | |
Selenium (L-Selenomethionine) | 100 mcg | |
Copper (Copper Gluconate) | 1 mg | |
Manganese (Manganese Glycinate) | 5 mg | |
Chromium (Chromium Polynicotinate) | 100 mcg | |
Molybdenum (Molybdenum Glycinate) | 50 mcg | |
Betaine HCl | 25 mg | |
Boron (Boron Citrate) | 1 mg | |
Vanadium (Vanadyl Sulfate) | 50 mcg |
A serving contains 25 mg of vitamin B6, exceeding the European adult daily upper limit. The B6 is identified as Pyridoxal 5-Phosphate and Pyridoxine Hydrochloride, and B6 from food or other supplements adds to the daily total.
How this ingredient is rated
Ingredient Form & Label Quality100
The vitamin B6 source is identified as Pyridoxal 5-Phosphate and Pyridoxine Hydrochloride. The proportions of the two forms are not disclosed. The recorded check found no artificial dyes, titanium dioxide or talc.
Vitamin B6 Form Identification
The B6 source is identified as Pyridoxal 5-Phosphate and Pyridoxine Hydrochloride. The proportions of the two forms are not disclosed.
Clean Label and Excipient Purity
The recorded check found no artificial dyes, titanium dioxide or talc.
Dose, Safety & Label Transparency60
The 25 mg of B6 per serving exceeds the European adult daily upper limit; other sources also contribute to daily intake. The label identifies Pyridoxal 5-Phosphate and Pyridoxine Hydrochloride as the source.
Vitamin B6 Dose & Safety Policy
The 25 mg of B6 per serving exceeds the European adult daily upper limit; other sources also contribute to daily intake.
Label Transparency
The B6 source is disclosed as Pyridoxal 5-Phosphate and Pyridoxine Hydrochloride.
Value71
The whole-product serving costs about $0.53 for 25 mg of B6, a moderate cost per mg in the comparison.
Vitamin B6 Price Efficiency
The whole-product serving costs about $0.53 for 25 mg of B6, a moderate cost per mg in the comparison.
Manganese (Manganese Glycinate) · 5 mg OverallScore79
A serving lists 5 mg of manganese as glycinate and gluconate. The amounts supplied by each form are not known.
How this ingredient is rated
Active Ingredient Quality & Bioavailability72
Manganese glycinate and gluconate are listed, but the amount from each form is unknown.
Manganese Chemical Form
Manganese glycinate and gluconate are listed, but the amount from each form is unknown.
Dose, Safety & Label Transparency100
A serving lists 5 mg of elemental manganese.
Manganese Dosage Efficacy & Safety
The declared serving contains 5 mg of manganese.
Elemental Weight Disclosure
The elemental manganese amount is declared as 5 mg per serving.
Value50
About $0.53 per whole-product serving covers the entire product, not manganese alone.
Price per Serving vs. Median
The price comparison uses about $0.53 per whole-product serving.
Selenium (L-Selenomethionine) · 100 mcg OverallScore77
A serving provides 100 mcg of selenium as l-selenomethionine. At the listed price, the product costs about $1.07 per 200 mcg of selenium for comparison.
How this ingredient is rated
Active Ingredient Quality & Bioavailability100
The selenium is identified as L-selenomethionine, with the L form specifically named.
Selenium Chemical Form
The recorded form is L-selenomethionine, an organic form of selenium.
Form Transparency & Isomer Specificity
The name specifies the L form of selenomethionine.
Dose, Safety & Label Transparency88
The serving provides 100 mcg of selenium. It falls below the upper limit used in the evaluation, though food and other sources also contribute to total intake.
Dosage Efficacy Sweet Spot
A serving supplies 100 mcg of selenium, an amount used for selenium support.
Safety Margin & UL Adherence
The 100 mcg in a serving is below the upper limit used in the evaluation; food and other products also contribute to total selenium intake.
Value10
At the listed price, about $1.07 of the whole product corresponds to 200 mcg of selenium. The cost also covers any other ingredients.
Price per 200 mcg Serving
At the listed price, about $1.07 of the whole product corresponds to 200 mcg of selenium. The cost also covers any other ingredients.
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Report alternatives
Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
- Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
- The relationship between boron and magnesium status and bone mineral density in the human: a review.
- Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
- Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
- The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
- Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
- Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
- The association between dietary mineral intake and bone mineral density: a cross-sectional study.
- Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
- Association between RBC folate and lumbar bone mineral density in postmenopausal women, a cross-sectional study from NHANES 2009-2018.
- Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density.
- Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
- Relation of homocysteine, folate, and vitamin B12 to bone mineral density of postmenopausal women.
- Dietary intake of folate, but not vitamin B2 or B12, is associated with increased bone mineral density 5 years after the menopause: results from a 10-year follow-up study in early postmenopausal women.
- Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES.
- The Manganese-Bone Connection: Investigating the Role of Manganese in Bone Health.
- Associations of multiple metals with bone mineral density: A population-based study in US adults.
- Sex-specific associations of urinary mixed-metal concentrations with femoral bone mineral density among older people: an NHANES (2017-2020) analysis.
- Relationship between blood manganese and bone mineral density and bone mineral content in adults: A population-based cross-sectional study.